Gateway test
Dicamba
General Information
- Fact Sheet: Dicamba.pdf
- Product Names:
- Chemical Class: Benzoic acid herbicide
- Uses: Agricultural, industrial, and residential settings. Different forms of dicamba (acid and salts) have registered uses on rights-of-way areas, asparagus, barley, corn , grasses grown in pasture and rangeland, oats, proso millet, rye, sorghum, soybeans, sugarcane, and wheat, golf courses
and lawns. - Alternatives: Organic agriculture, Organic lawns care
- Beyond Pesticides rating: Toxic
Health and Environmental Effects
- Cancer: Suggestive (1, 2)
- Endocrine Disruption: Not documented
- Reproductive Effects: Yes (3)
- Neurotoxicity: Yes (3)
- Kidney/Liver Damage: Yes (4)
- Sensitizer/ Irritant: Yes (4)
- Birth/Developmental: Yes (5)
- Detected in Groundwater: Yes (3)
- Potential Leacher: Yes (6)
- Toxic to Birds: Yes (7, 8)
- Toxic to Fish/Aquatic Organisms: Yes (3)
- Toxic to Bees: Not documented
Residential Uses as Found in the ManageSafe™ Database
Additional Information
- Regulatory Status:
- EPA's Dicamba Background and Updates
- Beyond Pesticides Comments (September 2025)
- Registration of Dicamba for Use on Dicamba-Tolerant Crops (July 2025)
- EPA Announces Proposed Decision to Approve Registration for New Uses of Dicamba, Outlines New Measures to Protect Human Health, Environment (July 2025)
- Beyond Pesticides Comments (July 2024)
- Beyond Pesticides Comments (June 2024)
- Registration of Dicamba for Use on GE Crops
- Monsanto Petitions for Determinations of Nonregulated Status for Dicamba-Resistant Soybean and Cotton Varieties: Final Environmental Impact Statement (December 2014)
- EPA Reregistration Eligibility Decision (RED) signed (6/2006)
- Supporting information:
- Daily News Blog entries (Beyond Pesticides)
- Asthma, Children and Pesticides (Beyond Pesticides)
- NCAP Pesticide Factsheet (Northwest Coalition for Alternatives to Pesticides)
- PAN Pesticides Database:Dicamba (Pesticide Action Network)
- NPIC Dicamba Factsheet (National Pesticide Information Center)
- Studies [compiled from the Pesticide-Induced Diseases Database]
- Dicamba drift affects non-target plants and pollinators (Penn State, 2015)
- Comparison of pesticide levels in carpet dust and self-reported pest treatment practices in four US sites. Colt, Joanne et. al.2004. Journal of Exposure Analysis and Environmental Epidemiology 14, 74–83.
- Do Pesticides Affect Learning Behavior? Porter, Warren. 2004. Pesticides and You (Beyond Pesticides).
- Dicamba use and cancer incidence in the agricultural health study: an updated analysis. Lerro, C.C., Hofmann, J.N., Andreotti, G., Koutros, S., Parks, C.G., Blair, A., Albert, P.S., Lubin, J.H., Sandler, D.P. and Beane Freeman, L.E., 2020. International Journal of Epidemiology.
- Cancer incidence among pesticide applicators exposed to dicamba in the Agricultural Health Study. Samanic, C., et al. 2006. Environ Health Perspect 114(10):1521-1526.
- Developmental Toxicity of a Commercial Herbicide Mixture in Mice: I. Effects on Embryo Implantation and Litter Size. Cavieres, M., et al. 2002. Environ Health Perspect 110:1081-1085
- Amine Volatilization from Herbicide Salts: Implications for Herbicide Formulations and Atmospheric Chemistry. Sharkey, S.M., Hartig, A.M., Dang, A.J., Chatterjee, A., Williams, B.J. and Parker, K.M., 2022. Environmental Science & Technology.
- Exposure to pesticides and risk of Hodgkin lymphoma in an international consortium of agricultural cohorts (AGRICOH). Kim, J., Leon, M.E., Schinasi, L.H., Baldi, I., Lebailly, P., Freeman, L.E.B., Nordby, K.C., Ferro, G., Monnereau, A., Brouwer, M. and Kjaerheim, K., 2023. Cancer Causes & Control, pp.1-9.
- Dicamba and 2,4-D in the Urine of Pregnant Women in the Midwest: Comparison of Two Cohorts (2010–2012 vs. 2020–2022). Daggy, J.K. et al. (2024) Dicamba and 2,4-D in the urine of pregnant women in the Midwest: Comparison of two cohorts (2010–2012 vs. 2020–2022), Agrochemicals. Available at: https://www.mdpi.com/2813-3145/3/1/5.
- Proximity to residential and workplace pesticides application and the risk of progression of Parkinson's diseases in Central California. Li, S. et al. (2022) Proximity to residential and workplace pesticides application and the risk of progression of parkinson’s diseases in Central California, Science of The Total Environment. Available at: https://www.sciencedirect.com/science/article/pii/S0048969722079542.
- Persistence of triclopyr, dicamba, and picloram in the environment following aerial spraying for control of dense pine invasion. Rolando, C.A. et al. (2023) Persistence of Triclopyr, dicamba, and Picloram in the environment following aerial spraying for control of dense pine invasion, Invasive Plant Science and Management. Available at: https://www.cambridge.org/core/journals/invasive-plant-science-and-management/article/persistence-of-triclopyr-dicamba-and-picloram-in-the-environment-following-aerial-spraying-for-control-of-dense-pine-invasion/EC888894C5B7A927AD5E5A3E0C06CD8D.
- Impact of Endocrine Disrupting Pesticide Use on Obesity: A Systematic Review. Pérez-Bermejo, M. et al. (2024) Impact of Endocrine Disrupting Pesticide Use on Obesity: A Systematic Review, Biomedicines. Available at: https://www.mdpi.com/2227-9059/12/12/2677.
- Beyond the field: How pesticide drift endangers biodiversity. Albaseer, S. et al. (2024) Beyond the field: How pesticide drift endangers biodiversity, Environmental Pollution. Available at: https://www.sciencedirect.com/science/article/pii/S0269749124022437.
- Response of Wine Grape Cultivars to Simulated Drift Rates of 2,4-D, Dicamba, and Glyphosate, and 2,4-D or Dicamba Plus Glyphosate. Mohseni-Moghadam, M. et al. (2017) Response of Wine Grape Cultivars to Simulated Drift Rates of 2,4-D, Dicamba, and Glyphosate, and 2,4-D or Dicamba Plus Glyphosate, Weed Technology. Available at: https://www.cambridge.org/core/journals/weed-technology/article/response-of-wine-grape-cultivars-to-simulated-drift-rates-of-24d-dicamba-and-glyphosate-and-24d-or-dicamba-plus-glyphosate/1BAD9A48DD98F8896E56C6823A2EE4A4.
- Genotoxicity evaluation of 2,4-D, dicamba and glyphosate alone or in combination with cell reporter assays for DNA damage, oxidative stress and unfolded protein response . Mesnage, R. et al. (2021) ‘Genotoxicity evaluation of 2,4-D, dicamba and glyphosate alone or in combination with cell reporter assays for DNA damage, oxidative stress and unfolded protein response’, Food and Chemical Toxicology, 157, p. 112601. doi:10.1016/j.fct.2021.112601.
- Toxic and histopathological effects induced by exposure to the pesticide dicamba in carp Cyprinus carpio L. Korkmaz, N. Toxic and histopathological effects induced by exposure to the pesticide dicamba in carp Cyprinus carpio L. Environ Sci Pollut Res 31, 65790–65803 (2024). https://doi.org/10.1007/s11356-024-35674-9
- Exploring the Joint Association Between Agrichemical Mixtures and Pediatric Cancer. Taiba, J. et al. (2025) Exploring the Joint Association Between Agrichemical Mixtures and Pediatric Cancer, GeoHealth. Available at: https://agupubs.onlinelibrary.wiley.com/doi/10.1029/2024GH001236.
- Off-target pesticide movement: a review of our current understanding of drift due to inversions and secondary movement. Bish M, Oseland E, Bradley K. Off-target pesticide movement: a review of our current understanding of drift due to inversions and secondary movement. Weed Technology. 2021;35(3):345-356. doi:10.1017/wet.2020.138
- Investigations of the Sensitivity of Ornamental, Fruit, and Nut Plant Species to Driftable Rates of 2,4-D and Dicamba. Dintelmann, Brian & Warmund, Michele & Bish, Mandy & Bradley, Kevin. (2019). Investigations of the Sensitivity of Ornamental, Fruit, and Nut Plant Species to Driftable Rates of 2,4-D and Dicamba. Weed Technology. 34. 1-35. 10.1017/wet.2019.118.
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review. Matich, E. K., Laryea, J. A., Seely, K. A., Stahr, S., Su, L. J., & Hsu, P. C. (2021). Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review. Ecotoxicology and environmental safety, 219, 112327. https://doi.org/10.1016/j.ecoenv.2021.112327
Gateway Health and Environmental Effects Citations
1. Lerro, C.C., Hofmann, J.N., Andreotti, G., Koutros, S., Parks, C.G., Blair, A., Albert, P.S., Lubin, J.H., Sandler, D.P. and Beane Freeman, L.E., 2020. Dicamba use and cancer incidence in the agricultural health study: an updated analysis. International Journal of Epidemiology.https://doi.org/10.1093/ije/dyaa066
2. Cantor, K.P. 1992. Pesticides and other agricultural risk factors for non-Hodgkin’s lymphoma among men in Iowa and Minnesota. Cancer Res. 52:2447-2455. https://cancerres.aacrjournals.org/content/canres/52/9/2447.full.pdf
3. Northwest Coalition for Alternatives to Pesticides (NCAP), Pesticide Factsheets. http://www.pesticide.org/pesticide-factsheets.
4. Extension Toxicology Network (EXTOXNET) Pesticide Information Profiles. http://extoxnet.orst.edu/pips/ghindex.html
5. US EPA, 2000. Table 1: Toxicity Data by Category for Chemicals Listed under EPCRA Section 313. Toxic Release Inventory (TRI) Program. https://www.epa.gov/sites/production/files/documents/hazard_categories.pdf
6. Beyond Pesticides ChemWatch Factsheets. (Cited under factsheets on Beyond Pesticides Gateway; see top of individual chemical page)
7. Briggs, S.A. 1992. Basic Guide to Pesticides: Their Characteristics and Hazards. Washington, DC: The Rachel Carson Council, 98. https://www.cabdirect.org/cabdirect/abstract/19932334845
8. Mineau, P., A. Baril, B.T. Collins , J. Duffe, G. Joerman, R. Luttik. 2001. Reference values for comparing the acute toxicity of pesticides to birds. Reviews of Environmental Contamination and Toxicology 170:13-74. http://web.archive.org/web/20081006213641/http://www.abcbirds.org/abcprograms/policy/pesticides/aims/aims/toxicitytable.cfm








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