Gateway on Pesticide Hazards and Safe Pest Management
Beyond Pesticides offers resources below to evaluate the health and ecological effects of specific chemical exposure from ACTIVE INGREDIENTS in pesticide products, as well as regulatory information and supporting scientific documents. Because various pesticide products can contain more than one active ingredient, it is important to READ the LABEL to determine chemical components.
With 192 different active ingredients and counting, it is essential to establish the connection between the use of these chemicals and their respective hazards.
View the step-by-step guide on how to search for the active ingredient(s) in pesticide products below:
- Go to U.S. EPA's Pesticide Product and Label System and enter the product name. The generic product name may vary.
- After searching, click on the chemical ingredients tab or the link for the most recent label to find Active Ingredients.
Chemical List Label List
If one selects the chemical ingredients tab, skip to Step 4 . If not, proceed to step number 3
- To find the active ingredient(s) on the label, search for the page in the document containing the date of registration. Usually, the active ingredients section occurs within the first few pages of the label document.
- Return to the Beyond Pesticides Gateway and search for the active ingredient name in the yellow box to the right or from the list below.
- Fact Sheet: Rotenone.pdf
- Product Names:
- Chemical Class: Botanical insecticde
- Uses: Applied directly to water to manage fish populations in lakes, ponds, reservoirs, rivers, streams, and in aquaculture.
- Beyond Pesticides rating: Toxic
Health and Environmental Effects
- Cancer: Not documented
- Endocrine Disruption: Not documented
- Reproductive Effects: Not documented
- Neurotoxicity: Not documented
- Kidney/Liver Damage: Yes (4)
- Sensitizer/ Irritant: Yes (4)
- Birth/Developmental: Not documented
- Detected in Groundwater: Not documented
- Potential Leacher: Not documented
- Toxic to Birds: Not documented
- Toxic to Fish/Aquatic Organisms: Yes (4)
- Toxic to Bees: Yes (57)
- Regulatory Status:
- Supporting information:
- Rotenone Linked to Parkinson's Disease (Beyond Pesticides Daily News Archive)
- Cerebellar neurochemical and histopathological changes in rat model of Parkinson's disease induced by intrastriatal injection of rotenone.. Khadrawy YA, Mourad IM, Mohammed HS, et al. 2017. Gen Physiol Biophys. 36(1):99-108.
- Chronic exposure to rotenone, a dopaminergic toxin, results in peripheral neuropathy associated with dopaminergic damage.. Binienda ZK, Sarkar S, et al. 2013. Neurosci Lett. 541:233-7
- Environment-contact administration of rotenone: A new rodent model of Parkinson's disease.. Liu Y, Sun JD, Song LK, et al. 2015. Behav Brain Res.294:149-161
- Environmental Exposures and Parkinson's Disease.. Nandipati S, Litvan I. 2016. Int J Environ Res Public Health. 13(9).
- Environmental Neurotoxic Pesticide Exposure Induces Gut Inflammation and Enteric Neuronal Degeneration by Impairing Enteric Glial Mitochondrial Function in Pesticide Models of Parkinson’s Disease: Potential Relevance to Gut-Brain Axis Inflammation in Parki. Palanisamy, B.N., Sarkar, S., Malovic, E., Samidurai, M., Charli, A., Zenitsky, G., Jin, H., Anantharam, V., Kanthasamy, A. and Kanthasamy, A. The International Journal of Biochemistry & Cell Biology, p.106225.