Gateway on Pesticide Hazards and Safe Pest Management

Prallethrin

General Information

• Fact Sheet: Synthetic Pyrethroids.pdf
• Product Names:

  Cirrus™ Fogging Concentrate (MGK®)

  Duet® Dual Action Adulticide (Clarke)

  Multicide® Fogging Concentrate (McLaughlin Gormley King Company)

  Prallethrin Technical (Sumitomo Chemical Australia Pty Ltd) 

  Raid® Multi Insect Killer 7 (S.C. Johnson) 

  Repel-X^®(Farnam Companies, Inc)

  SSS Flying Insect spray (Triple S)

• Chemical Class: (Type I) Synthetic Pyrethroid Insecticide
• Uses: Agriculture, Residential / household, animal health (pet-cleaning products, pet-flea collar treatments), and against various insects (mosquitoes, ants, houseflies, fleas, ticks and cockroaches)
• Alternatives: ManageSafe™, Organic Agriculture, Least-toxic mosquito control
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Possible (104)
• Endocrine Disruption: Likely (103, 104, 105, 108)
• Reproductive Effects: Not documented
• Neurotoxicity: Yes (105, 106)
• Kidney/Liver Damage: Yes (109)
• Sensitizer/ Irritant: Yes (107)
• Birth/Developmental: Not documented
• Detected in Groundwater: Not documented
• Potential Leacher: Not documented
• Toxic to Birds: Not documented
• Toxic to Fish/Aquatic Organisms: Yes (103)
• Toxic to Bees: Yes (103)

Residential Uses as Found in the ManageSafe™ Database

• Fleas
• Mosquitoes
• Ticks
• Cockroaches
• Carpenter Ants
• Fire Ants
• Ants

Additional Information

• Regulatory Status:
  • Pesticide Registration Review: Proposed Interim Decisions for Several Pesticides (05/05/2020)
  • NOTICE OF PESTICIDE: Registration (under FIFRA) of Duet HD Dual-Action Adulticide (01/29/16)
    
  • Prallethrin; Pesticide Tolerances a Rule by the Environmental Protection Agency (10/29/2014)
  • Registration Review; Pesticide Dockets Opened for Review and Comment and Other Action (07/06/2012)
  • Prallethrin Summary Document / and Preliminary Work Plan (06/08/2012)
  • Prallethrin: Human Health Risk Assessment for the Public Health Use of Mosquito Adulticides Containing Prallethrin.(11/21/2003)
  • Label Change: WHITMIRE TC 161 INJECTION SYSTEM (09/23/2002)
    
  • Registration of EVERCIDE® Residual And & Roach Spray (EPA Reg. No. 1021-1601), Containing the New Active Ingredient Prallethrin (ETOC) (07/11/1997)
  • NOTICE OF PESTICIDE: Registration (under FIFRA) of WHITMIRE TC 161 INJECTION SYSTEM (04/09/1997)
• Supporting information:
  • Appendix D Pesticide Technical Background Information (Blankinship & Associates, Inc)
  • Pesticide Database: Prallethrin (Pesticide Action Network)
  • Pesticide Properties DataBase (PPDB): Prallethrin (University of Hertforshire, UNited Kingdom)
  • Specifications and Evaluations or Public Health Pesticides: PRALLETHRIN (World Health Organization) 
• Studies:
  • Allethrin and prallethrin stimulates MUC5AC expression through oxidative stress in human airway epithelial cells Na, H.G., Kim, Y.D., Choi, Y.S., Bae, C.H. and Song, S.Y., 2018. Biochemical and biophysical research communications, 503(1), pp.316-322.
  • Cardiac Conduction Disturbance Due To Prallethrin (Pyrethroid) Poisoning Bhaskar, E.M., Moorthy, S., Ganeshwala, G. and Abraham, G., 2010. Journal of Medical Toxicology, 6(1), pp.27-30.