Gateway on Pesticide Hazards and Safe Pest Management

Beyond Pesticides offers resources below to evaluate the health and ecological effects of specific chemical exposure from ACTIVE INGREDIENTS in pesticide products, as well as regulatory information and supporting scientific documents. Because various pesticide products can contain more than one active ingredient, it is important to READ the LABEL to determine chemical components.

With 192 different active ingredients and counting, it is essential to establish the connection between the use of these chemicals and their respective hazards.

View the step-by-step guide on how to search for the active ingredient(s) in pesticide products below:

1. Go to U.S. EPA's Pesticide Product and Label System and enter the product name. The generic product name may vary.
   
2. After searching, click on the chemical ingredients tab or the link for the most recent label to find Active Ingredients.
                Chemical List                                            Label List 
   
   If one selects the chemical ingredients tab, skip to Step 4 . If not, proceed to step number 3
   
   
3. To find the active ingredient(s) on the label, search for the page in the document containing the date of registration. Usually, the active ingredients section occurs within the first few pages of the label document.
   
   
4. Return to the Beyond Pesticides Gateway and search for the active ingredient name in the yellow box to the right or from the list below. 
   
   

Florpyrauxifen-benzyl

Updated June 2019

General Information

• Product Names:

  ProcellaCOR (SePRO)

• Chemical Class: Arylpicolinate class of herbicides; Synthetic auxin
• Uses: Systemic herbicide used on rice, post-emergence grass, sedge, and broadleaf weed control in several states and for national use to control invasive species such as hydrilla, watermilfoil, crested floating heart in freshwater aquatic sites.
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Suggestive Evidence (71)
• Endocrine Disruption: Suggestive Evidence (71)
• Reproductive Effects: Not documented
• Neurotoxicity: Not documented
• Kidney/Liver Damage: Suggestive Evidence (71)
• Sensitizer/ Irritant: Not documented
• Birth/Developmental: Not documented
• Detected in Groundwater: Not documented
• Potential Leacher: Not documented
• Toxic to Birds: Not documented
• Toxic to Fish/Aquatic Organisms: Not documented
• Toxic to Bees: Not documented

Additional Information

• Regulatory Status:
  • EPA Registration (2017)
• Supporting information:
  • EFSA Risk Assessment (2018)
• Studies:
• Enhanced Herbicide Metabolism and Target Site Mutation Enabled the Multiple Resistance to Cyhalofop-butyl, Florpyrauxifen-benzyl, and Penoxsulam in Echinochloa crus-galli. Yu, X. et al. (2024) Enhanced Herbicide Metabolism and Target Site Mutation Enabled the Multiple Resistance to Cyhalofop-butyl, Florpyrauxifen-benzyl, and Penoxsulam in Echinochloa crus-galli, Journal of Agricultural and Food Chemistry. Available at: https://pubs.acs.org/doi/abs/10.1021/acs.jafc.4c02450.
• Short-term immunotoxicity induced by florpyrauxifen-benzyl herbicide exposure in the spleen of male albino mice. Morsi, D. S., Abu Quora, H. A., AboShabaan, H. S., El-Garawani, I. M., Abdel Moneim, A. E., & Hathout, H. M. R. (2024). Short-term immunotoxicity induced by florpyrauxifen-benzyl herbicide exposure in the spleen of male albino mice. Journal of experimental zoology. Part A, Ecological and integrative physiology, 341(6), 658–671. https://doi.org/10.1002/jez.2814
• The induced hepatotoxicity and genotoxicity in Oreochromis niloticus exposed to a newly released florpyrauxifen-benzyl herbicide. Nabet, N. et al. (2025) The induced hepatotoxicity and genotoxicity in Oreochromis niloticus exposed to a newly released florpyrauxifen-benzyl herbicide, Ecotoxicology. Available at: https://link.springer.com/article/10.1007/s10646-025-02864-1.