Gateway on Pesticide Hazards and Safe Pest Management

Updates from the Daily News Blog

Glyphosate, When Combined with Other Stressors, Results in Breast Cancer Development
October 9, 2019

Herbicide Drift from Agricultural Use Found to Harm Bird Habitat
September 13, 2019

Germany Moves to Phase-Out Glyphosate/Roundup; EPA Unmoved
September 11, 2019

Health and Environmental Groups Call on EPA to Revoke Glyphosate’s Registration
September 4, 2019

EPA Refuses to Approve Labeling that Discloses Roundup (Glyphosate) as a Carcinogen
August 12, 2019

Dicamba Herbicide Poses Greater Threat of Drift when Mixed with Glyphosate
July 18, 2019

Responding to Pressure from Advocates, USDA’s National Organic Program Announces Stricter Enforcement for Organic Container Systems
June 5, 2019

University of California Suspends Use of Weed Killer, Glyphosate, as Bans Mount Across the U.S.
May 24, 2019

Glyphosate Exposure Linked to Fatty Liver Disease in Humans, Adding Weight to Earlier Animal Studies
May 22, 2019

Jury Awards $2 Billion for Damages in Third Federal Roundup Cancer Case
May 15, 2019

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Glyphosate

Updated March 2019

General Information

• Fact Sheet: bp-fact-glyosphate.082017.pdf
• Product Names:

  Roundup (Monnsanto)
  Polado (Monsanto)
  Accord (Monsanto)
  Clearout (Albaugh)
  Departure (Syngenta)
  Extreme (BASF) formulated with Imazethapyr
  Backdraft (BASF) formulated with Imazaquin
  Rage (FMC) formulated with Carentrazone-ethyl
  Ortho Season-Long Grass & Weed Killer (Scotts)
  Knockout (Libertas)
  Cornerstone (Winfield)
  Rodeo (Monsanto)

• Chemical Class: Phosphanoglycine herbicide
• Uses: Non selective herbicide, or at low rates a plant growth regulator
• Alternatives: Organic agriculture, Organic land managment
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Yes (6, 70)
• Endocrine Disruption: Yes (7)
• Reproductive Effects: Yes (13, 8)
• Neurotoxicity: Not documented
• Kidney/Liver Damage: Yes (7)
• Sensitizer/ Irritant: Yes (8)
• Birth/Developmental: Not documented
• Detected in Groundwater: Not documented
• Potential Leacher: Not documented
• Toxic to Birds: Not documented
• Toxic to Fish/Aquatic Organisms: Yes (4)
• Toxic to Bees: Not documented

Residential Uses as Found in the ManageSafe™ Database

• Dandelions
• Annual Bluegrass
• Clover
• Ground Ivy
• Japanese Knotweed
• Chickweed

Additional Information

• Regulatory Status:
  • Beyond Pesticides' Draft Human Health and Ecological Risk Assessments for Glyphosate comments (04/2018)
  • Draft Human Health and Ecological Risk Assessments for Glyphosate (2017)
  • Revised Glyphosate Issue Paper: Evaluation of Carcinogenic Potential (2017)
  • Beyond Pesticides' Evaluation of the Carcinogenic Potential comments (10/2016)
  • Glyphosate Listed Effective July 7, 2017, as Known to the State of California to Cause Cancer (OEHHA, 2017)
  • Beyond Pesticides' Notice of Intent to List (California) comments (10/2015)
  • Beyond Pesticides' Enlist Duo registration comments (12/2016)
  • EPA Meeting Materials for the December 13-16, 2016 Scientific Advisory Panel on the Carcinogenic Potenial of Glyphosate.
  • Registration of Enlist Duo (EPA, 2014)
  • FInal work plan for Glyphosate Registration review (2009)
  • EPA Reregistration Eligibility Decision (RED) signed (9/1993)
• Supporting information:
  • Daily News Blog
  • Report- Glyphosate: Unsafe on Any Plate
  • Beyond Pesticides' letter to EPA  calling for residue testing (12/2015)
  • Agricultural Uses of Antibiotics Escalate Bacterial Resistance (Pesticides and You, Winter 2016-2017)
  • Asthma, Children and Pesticides (Beyond Pesticides)
  • Children & Lawn Chemicals Don't Mix (Beyond Pesticides)
  • GMO Factsheet (Beyond Pesticides)
  • NCAP Glyphosate Factsheet (Northwest Coalition for Alternatives to Pesticides)
  • PAN Pesticides Database:Glyphosate (Pesticide Action Network)
  • Scorecard Glyphosate Factsheet (Environmental Defense Fund)
  • PAN UK Glyphosate Factsheet (Pesticide Action Network UK)
  • CHEJ Glyphosate Factsheet (Children's Health Environmental Coalition)
  • EPA Technical Factsheet
• Studies:
  • • Exposure to Glyphosate-Based Herbicides and Risk for Non-Hodgkin Lymphoma: A Meta-Analysis and Supporting Evidence. Zhang, L., Rana, I., Taioli, E., Shaffer, R.M. and Sheppard, L., 2019. Mutation Research/Reviews in Mutation Research.
  • Multiomics reveal non-alcoholic fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide. Mesnage, R, Renney, G, Seralini, GE, et al. 2017. Scientific Reports 7, Article number: 39328 
  • Glyphosate pathways to modern diseases V: Amino acid analogue of glycine in diverse proteins. Samsel, A, Seneff, S. 2016. J Biological Physics and Chemistry.16:9-46
  • IARC Classification of Glyphosate as a "probable" carcinogen (2015).
    Read the Daily News Blog
  • Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure. Mesnage, R, Arno, M, Contanzo, M et al., 2015. Environmental Health 14:70.
  • Glyphosate Formulations Induce Apoptosis and Necrosis in Human Umbilical, Embryonic, and Placental Cells. Benachour, et al. 2009. Chem. Res. Toxicol. 22 (1), pp 97–105.
  • Do Pesticides Affect Learning Behavior? The neuro-endocrine-immune connection. Porter, Warren. 2004. Pesticides and You (Beyond Pesticides)
  • A Case–Control Study of Non-Hodgkin Lymphoma and Exposure to Pesticides Journal of the American Cancer Society, 1999.
  • Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells. Benachour N, Séralini GE. Chemical Research in Toxicology. 2009 Jan;22(1):97-105
  • Top 15 Farmworker Poison