Gateway on Pesticide Hazards and Safe Pest Management
Glyphosate
Updated March 2019
General Information
- Fact Sheet: bp-fact-glyosphate.082017.pdf
- Product Names:
- Chemical Class: Phosphanoglycine herbicide
- Uses: Non selective herbicide, or at low rates a plant growth regulator
- Alternatives: Organic agriculture, Organic land managment
- Beyond Pesticides rating: Toxic
Health and Environmental Effects
- Cancer: Yes (6, 70)
- Endocrine Disruption: Yes (7)
- Reproductive Effects: Yes (13, 8)
- Neurotoxicity: Not documented
- Kidney/Liver Damage: Yes (7)
- Sensitizer/ Irritant: Yes (8)
- Birth/Developmental: Not documented
- Detected in Groundwater: Not documented
- Potential Leacher: Not documented
- Toxic to Birds: Not documented
- Toxic to Fish/Aquatic Organisms: Yes (4)
- Toxic to Bees: Not documented
Residential Uses as Found in the ManageSafe™ Database
Additional Information
- Regulatory Status:
- Beyond Pesticides' Draft Human Health and Ecological Risk Assessments for Glyphosate comments (04/2018)
- Draft Human Health and Ecological Risk Assessments for Glyphosate (2017)
- Revised Glyphosate Issue Paper: Evaluation of Carcinogenic Potential (2017)
- Beyond Pesticides' Evaluation of the Carcinogenic Potential comments (10/2016)
- Glyphosate Listed Effective July 7, 2017, as Known to the State of California to Cause Cancer (OEHHA, 2017)
- Beyond Pesticides' Notice of Intent to List (California) comments (10/2015)
- Beyond Pesticides' Enlist Duo registration comments (12/2016)
- EPA Meeting Materials for the December 13-16, 2016 Scientific Advisory Panel on the Carcinogenic Potenial of Glyphosate.
- Registration of Enlist Duo (EPA, 2014)
- FInal work plan for Glyphosate Registration review (2009)
- EPA Reregistration Eligibility Decision (RED) signed (9/1993)
- Supporting information:
- Daily News Blog
- Report- Glyphosate: Unsafe on Any Plate
- Beyond Pesticides' letter to EPA calling for residue testing (12/2015)
- Agricultural Uses of Antibiotics Escalate Bacterial Resistance (Pesticides and You, Winter 2016-2017)
- Asthma, Children and Pesticides (Beyond Pesticides)
- Children & Lawn Chemicals Don't Mix (Beyond Pesticides)
- GMO Factsheet (Beyond Pesticides)
- NCAP Glyphosate Factsheet (Northwest Coalition for Alternatives to Pesticides)
- PAN Pesticides Database:Glyphosate (Pesticide Action Network)
- Scorecard Glyphosate Factsheet (Environmental Defense Fund)
- PAN UK Glyphosate Factsheet (Pesticide Action Network UK)
- CHEJ Glyphosate Factsheet (Children's Health Environmental Coalition)
- EPA Technical Factsheet
- Studies:
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- Exposure to Glyphosate-Based Herbicides and Risk for Non-Hodgkin Lymphoma: A Meta-Analysis and Supporting Evidence. Zhang, L., Rana, I., Taioli, E., Shaffer, R.M. and Sheppard, L., 2019. Mutation Research/Reviews in Mutation Research.
- Multiomics reveal non-alcoholic fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide. Mesnage, R, Renney, G, Seralini, GE, et al. 2017. Scientific Reports 7, Article number: 39328
- Glyphosate pathways to modern diseases V: Amino acid analogue of glycine in diverse proteins. Samsel, A, Seneff, S. 2016. J Biological Physics and Chemistry.16:9-46
- IARC Classification of Glyphosate as a "probable" carcinogen (2015).
Read the Daily News Blog - Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure. Mesnage, R, Arno, M, Contanzo, M et al., 2015. Environmental Health 14:70.
- Glyphosate Formulations Induce Apoptosis and Necrosis in Human Umbilical, Embryonic, and Placental Cells. Benachour, et al. 2009. Chem. Res. Toxicol. 22 (1), pp 97–105.
- Do Pesticides Affect Learning Behavior? The neuro-endocrine-immune connection. Porter, Warren. 2004. Pesticides and You (Beyond Pesticides)
- A Case–Control Study of Non-Hodgkin Lymphoma and Exposure to Pesticides Journal of the American Cancer Society, 1999.
- Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells. Benachour N, Séralini GE. Chemical Research in Toxicology. 2009 Jan;22(1):97-105
- Top 15 Farmworker Poison
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