Gateway on Pesticide Hazards and Safe Pest Management

Vinclozolin

General Information

• Product Names:
  Ronilan (BASF)
  Curalan (BASF)

• Chemical Class: Morpholine fungicide
• Uses: Canola and imported grapes
• Alternatives: Organic agriculture
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Possible (8)
• Endocrine Disruption: Yes (30, 36)
• Reproductive Effects: Yes (8)
• Neurotoxicity: Not documented
• Kidney/Liver Damage: Not documented
• Sensitizer/ Irritant: Yes (8)
• Birth/Developmental: Not documented
• Detected in Groundwater: Not documented
• Potential Leacher: Not documented
• Toxic to Birds: Not documented
• Toxic to Fish/Aquatic Organisms: Yes (8)
• Toxic to Bees: Not documented

Residential Uses as Found in the ManageSafe™ Database

• Mold

Additional Information

• Regulatory Status:
  • RED signed 10/2000
• Supporting information:
  • PAN Pesticides Database: Vinclozolin (Pesticide Action Network)
• Studies:
• Effects of processing on pesticide residues in peaches intended for baby food.. Balinova AM, Mladenova RI, Shtereva DD. 2006. Food Addit Contam.23(9):895-901
• Environmental antiandrogens: low doses of the fungicide vinclozolin alter sexual differentiation of the male rat.. Gray LE, et al. 1999. Toxicol Ind Health;15(1-2):48-64
• Effects of the endocrine disruptor vinclozolin in male reproduction: a systematic review and meta-analysis. Feijó, M., Martins, R.V., Socorro, S., Pereira, L. and Correia, S., 2021. Biology of Reproduction.
• Environmentally induced epigenetic transgenerational inheritance of altered Sertoli cell transcriptome and epigenome: molecular etiology of male infertility.. Guerrero-Bosagna C, Savenkova M, Haque MM, et al. 2013. PLoS One. 8(3):e59922
• Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility. Anway, M.D. et al. 2005. Science: 308(5727) pp. 1466 - 1469