Gateway on Pesticide Hazards and Safe Pest Management

Pyriproxyfen

General Information

• Product Names:

  Archer Insct Growth Regulator (Sygenta)
  Country Vet Roach Embargo with Growth Inhibitor (FMC) formulated with Esfenvalerate
  Nylar (McGlaughin Gomrly King)
  Seper Nylar E.C. (Wellmark)
  Sumilarv (Sumitomo)
  Unicorn IGR (Phaeton)
  I.G. Regulator (Control Solutions)
  Knack (Valent)
  Distance Insect Growth Regulator (Valent)
  Esteem Insect Growth Regulator (Valent)
   Proxy (Makhteshim)

• Chemical Class: Unclassified
• Uses: Agriculture, structural pest control
• Alternatives: Organic agriculture, Organic lawn care
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Insufficiently Studied
• Endocrine Disruption: Likely (194, 195)
• Reproductive Effects: Likely (196, 200)
• Neurotoxicity: Possible (201)
• Kidney/Liver Damage: Yes (MSDS)
• Sensitizer/ Irritant: Not Likely
• Birth/Developmental: Likely (200, 201)
• Detected in Groundwater: Low (203)
• Potential Leacher: Parent = Slight; Metabolite = Yes (204)
• Toxic to Birds: Possible (202)
• Toxic to Fish/Aquatic Organisms: Yes (43, 195)
• Toxic to Bees: Yes (197, 198, 199)

Residential Uses as Found in the ManageSafe™ Database

• Fleas
• Ants
• Cockroaches
• Carpet Beetle
• Fire Ants

Additional Information

• Supporting information:
  • PAN Pesticides Database: Pyriproxyfen
• Studies:
  • Fate of pyriproxyfen in soils and plants. Devillers, J., 2020. Toxics, 8(1), p.20.
  • Determination by chromatography and cytotoxotoxic and oxidative effects of pyriproxyfen and pyridalyl. de Oliveira, M.D.D.A., de Almeida, P.M., Martins, F.A., Cavalcante, A.A.D.C.M., dos Santos, T.D.J.A., Feitosa, C.M., Rai, M., dos Reis, A.C. and da Costa Júnior, J.S., 2019. Chemosphere, 224, pp.398-406.
  • The enantioselective environmental behavior and toxicological effects of pyriproxyfen in soil. Liu, H., Yi, X., Bi, J., Wang, P., Liu, D. and Zhou, Z., 2019. Journal of hazardous materials, 365, pp.97-106.