Gateway on Pesticide Hazards and Safe Pest Management

Beyond Pesticides offers resources below to evaluate the health and ecological effects of specific chemical exposure from ACTIVE INGREDIENTS in pesticide products, as well as regulatory information and supporting scientific documents. Because various pesticide products can contain more than one active ingredient, it is important to READ the LABEL to determine chemical components.

With 192 different active ingredients and counting, it is essential to establish the connection between the use of these chemicals and their respective hazards.

View the step-by-step guide on how to search for the active ingredient(s) in pesticide products below:

1. Go to U.S. EPA's Pesticide Product and Label System and enter the product name. The generic product name may vary.
   
2. After searching, click on the chemical ingredients tab or the link for the most recent label to find Active Ingredients.
                Chemical List                                            Label List 
   
   If one selects the chemical ingredients tab, skip to Step 4 . If not, proceed to step number 3
   
   
3. To find the active ingredient(s) on the label, search for the page in the document containing the date of registration. Usually, the active ingredients section occurs within the first few pages of the label document.
   
   
4. Return to the Beyond Pesticides Gateway and search for the active ingredient name in the yellow box to the right or from the list below. 
   
   

Metconazole

General Information

• Product Names:
  Cramba (BASF)
  NIP Suite Cereals of Seed Protectant (Valent) formulated with Clothianidin, and  Metalaxyl

  Multiva (BASF) formulated with Pyraclostrobin

  BAS 556 (BASF) formulated with Pyraclostrobin

• Chemical Class: Triazole
• Uses: Fungicide proposed for control of Black Sigatoka disease (Mycosphaerella fijiensis) on bananas grown outside the US.
• Alternatives: Organic agriculture

Health and Environmental Effects

• Cancer: Not likely (39)
• Endocrine Disruption: Not documented
• Reproductive Effects: Not documented
• Neurotoxicity: Not documented
• Kidney/Liver Damage: Yes (39)
• Sensitizer/ Irritant: Slightly (39)
• Birth/Developmental: Not documented
• Detected in Groundwater: Not documented
• Potential Leacher: Not documented
• Toxic to Birds: Not documented
• Toxic to Fish/Aquatic Organisms: Yes (MSDS)
• Toxic to Bees: Not documented

Additional Information

• Regulatory Status:
  • Not registered, Import Tolerances Established (8/2006)
• Supporting information:
  • PAN Pesticides Database - Metconazole (Pesticide Action Network)
• Studies:
• Triazole pesticides exposure impaired steroidogenesis associated to an increase in AHR and CAR expression in testis and altered sperm parameters in chicken. Serra, L., Bourdon, G., Estienne, A., Fréville, M., Ramé, C., Chevaleyre, C., Didier, P., Chahnamian, M., Ganier, P., Pinault, F., Froment, P., & Dupont, J. (2023). Triazole pesticides exposure impaired steroidogenesis associated to an increase in AHR and CAR expression in testis and altered sperm parameters in chicken. Toxicology reports, 10, 409–427. https://doi.org/10.1016/j.toxrep.2023.03.005
• Evaluation of the Aquatic Toxicity of Several Triazole Fungicides. Boros, B.-V., Roman, D.-L., & Isvoran, A. (2024). Evaluation of the Aquatic Toxicity of Several Triazole Fungicides. Metabolites, 14(4), 197. https://doi.org/10.3390/metabo14040197