Gateway on Pesticide Hazards and Safe Pest Management

Beyond Pesticides offers resources below to evaluate the health and ecological effects of specific chemical exposure from ACTIVE INGREDIENTS in pesticide products, as well as regulatory information and supporting scientific documents. Because various pesticide products can contain more than one active ingredient, it is important to READ the LABEL to determine chemical components.

With 192 different active ingredients and counting, it is essential to establish the connection between the use of these chemicals and their respective hazards.

View the step-by-step guide on how to search for the active ingredient(s) in pesticide products below:

1. Go to U.S. EPA's Pesticide Product and Label System and enter the product name. The generic product name may vary.
   
2. After searching, click on the chemical ingredients tab or the link for the most recent label to find Active Ingredients.
                Chemical List                                            Label List 
   
   If one selects the chemical ingredients tab, skip to Step 4 . If not, proceed to step number 3
   
   
3. To find the active ingredient(s) on the label, search for the page in the document containing the date of registration. Usually, the active ingredients section occurs within the first few pages of the label document.
   
   
4. Return to the Beyond Pesticides Gateway and search for the active ingredient name in the yellow box to the right or from the list below. 
   
   

Fludioxonil

General Information

• Product Names:

  Cannonball (Syngenta)
  Graduate (Syngenta)
  Hurricane (Syngenta) formulated with Metalaxyl-M
  Maixm (Syngenta)
  Medallion (Syngenta)
  Scholar (Syngenta)
  Sporgard (Lanxess)
  Tc 281 (Whitmire)
  EFOG-80 (Pace)
  Shield-brite (Pace)

• Chemical Class: Unclassified
• Uses: Fungicide
• Alternatives: Organic agriculture
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Possible (1, 2)
• Endocrine Disruption: Likely (1, 3)
• Reproductive Effects: Possible (3)
• Neurotoxicity: Possible (4, 5)
• Kidney/Liver Damage: Yes (6)
• Sensitizer/ Irritant: Yes (6)
• Birth/Developmental: Possible (7, 8)
• Detected in Groundwater: Possible (9)
• Potential Leacher: Low (6)
• Toxic to Birds: Possible (10)
• Toxic to Fish/Aquatic Organisms: Yes (6)
• Toxic to Bees: Yes (6)

Additional Information

• Supporting information:
  • PAN Pesticides Database:Fludioxonil (Pesticide Action Network)
• Studies [compiled from the Pesticide-Induced Diseases Database]
  • Effect of nonpersistent pesticides on estrogen receptor, androgen receptor, and aryl hydrocarbon receptor.. Medjakovic S, Zoechling A, Gerster P, et al. 2014. Environ Toxicol. 29(10):1201-16
  • A Th2-type immune response and low-grade systemic inflammatory reaction as potential immunotoxic effects in intensive agriculture farmers exposed to pesticides . Lozano-Paniagua, D. et al. (2024) ‘A th2-type immune response and low-grade systemic inflammatory reaction as potential immunotoxic effects in intensive agriculture farmers exposed to pesticides’, Science of The Total Environment, 938, p. 173545. doi:10.1016/j.scitotenv.2024.173545.
  • Toxic and Behavioral Effects to Carabidae of Seed Treatments Used on Cry3Bb1- and Cry1Ab/c-Protected Corn. Christopher A. Mullin, Michael C. Saunders, Timothy W. Leslie, David J. Biddinger, Shelby J. Fleischer, Toxic and Behavioral Effects to Carabidae of Seed Treatments Used on Cry3Bb1- and Cry1Ab/c-Protected Corn, Environmental Entomology, Volume 34, Issue 6, 1 December 2005, Pages 1626–1636, https://doi.org/10.1603/0046-225X-34.6.1626
  • A cumulative dietary pesticide exposure score based on produce consumption is associated with urinary pesticide biomarkers in a U.S. biomonitoring cohort. Temkin, A. et al. (2025) A cumulative dietary pesticide exposure score based on produce consumption is associated with urinary pesticide biomarkers in a U.S. biomonitoring cohort, International Journal of Hygiene and Environmental Health. Available at: https://www.sciencedirect.com/science/article/pii/S1438463925001361.