Gateway on Pesticide Hazards and Safe Pest Management

Updates from the Daily News Blog

Acute Pesticide Incidents May Lead to Loss of Smell
January 23, 2019

USDA Capitulates to the Agrichemical Industry with Final GE Labeling Rule
January 8, 2019

Study of Rural New York State Homes Finds Pesticides in Every Sample Tested
October 18, 2018

Weeds on Missouri Cropland Found To Be Resistant to Six Different Herbicides
August 2, 2018

Tell U.S. Fish and Wildlife Service to Eliminate Pesticide Use on Refuges
May 21, 2018

National Wildlife Refuges Contaminated with Thousands of Pounds of Toxic Pesticides
May 15, 2018

State Proposes Rule to Restrict Sale of Dicamba and 2,4-D, Herbicides that Damage Crops
April 4, 2018

Take Action: Don’t Allow Dow Chemical to Poison Farms and Communities
December 4, 2017

Herbicide Caused Antibiotic Resistance Not Regulated
November 21, 2017

Veterans' Coverage of Agent Orange-Related Diseases Delayed
November 9, 2017

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2,4-D

General Information

• Fact Sheet: 2-4-D.pdf
• Product Names:

  Crossbow (Dow), formulated with Triclopyr, Petroleum distillates
  GlyMIX MT (Dow), formulated with Glyphosate
  Grazon P+D (Dow)
  Pathway (Dow)
  Aqua-Kleen (Nufarm America)
  Barrage (Helena Chemical)
  Malerbane (Aventis)
  Weedone (Nufarm America)
  Weedtrine- II (Nufarm America)

• Chemical Class: Phenoxy herbicide
• Uses: Registered for field, fruit, and vegetable crops, turf, lawns, rights-of-way, aquatic sites, forestry applications, post-emergence broadleaf weeds, plant growth regulator in citrus
• Alternatives: Organic agriculture,  Organic Lawn care
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Yes (4)
• Endocrine Disruption: Probable (5)
• Reproductive Effects: Yes (6)
• Neurotoxicity: Yes (7)
• Kidney/Liver Damage: Yes (7)
• Sensitizer/ Irritant: Yes (4)
• Birth/Developmental: Yes (4)
• Detected in Groundwater: Yes (4)
• Potential Leacher: Yes (7)
• Toxic to Birds: Yes (4)
• Toxic to Fish/Aquatic Organisms: Yes (8)
• Toxic to Bees: Yes (4)

Residential Uses as Found in the ManageSafe™ Database

• Dandelions
• Clover
• Ground Ivy
• Plantains
• Japanese Knotweed

Additional Information

• Regulatory Status:
  • Beyond Pesticides' comments on Preliminary Ecological Risk Assessment for Registration review (7/2017)
  • EPA Registration Review (2017)
  • Beyond Pestides' comments on registration of Enlist Duo (12/2016)
  • Registration of Enlist Duo (2014)
  • EPA Reregistration Eligibility Document (RED) signed (6/2005)
  • Beyond Pesticides' RED comments (8/2004)
• Supporting information:
  • Daily News Blog entries (Beyond Pesticides)
  • Asthma, Children and Pesticides (Beyond Pesticides)
  • Children & Lawn Chemicals Don't Mix (Beyond Pesticides)
  • The Safer Choice (Beyond Pesticides)
  • NCAP 2,4-D Factsheet (Northwest Coalition for Alternatives to Pesticides)
  • PAN Pesticides Database: 2,4-D (Pesticide Action Network)
• Studies:
  • IARC Monographs evaluate DDT, lindane, and 2,4-D. (2015) 
  • 2,4-Dichlorophenoxyacetic acid (2,4-D)-resistant crops and the potential for evolution of 2,4-D-resistant weeds. Egan JF, Maxwell BD, Mortensen DA, et al. 2011. Proc Natl Acad Sci. 108(11): E37.
  • Cancer and pesticides: an overview and some results of the Italian multicenter case-control study on hematolymphopoietic malignancies
    Miligi, L., et al. 2006. Annals of the New York Academy of Sciences.
  • Breast cancer risk in Hispanic agricultural workers in California
    Mills, P.K. and Yang, R. 2005. International Journal of Occupational and Environmental Health.
  • Lymphohematopoietic cancers in the United Farm Workers of America (UFW), 1988-2001.  Mills PK, Yang R, Riordan D. 2005. Cancer Causes Control.
  • Herbicide exposure and the risk of transitional cell carcinoma of the urinary bladder in Scottish terriers, Glickman, et. al. 2004. Journal of the American Medical Association.
  • Biomarker correlations of urinary 2,4-D levels in foresters: genomic instability and encodrine disruption. Garry, V.F., et al. 2001. Environ Health Pers.
  • A Case–Control Study of Non-Hodgkin Lymphoma and Exposure to Pesticides Journal of the American Cancer Society, 1999.
  • Pesticides in Household Dust and Soil: Exposure Pathways for Children of Agricultural Families, Simcox, et. al. 1995.Environmental Health Perspectives.
  • Pesticides and non-Hodgkin's lymphoma. Zahm SH and Blair A. 1992. Cancer Res.