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Updates from the Daily News Blog

Pervasive Pesticide Contamination of Beehives Across Europe, the First EU-Wide Study of Its Kind
January 28, 2026

Dietary Pesticide Exposure Study Stresses Need for More Accurate Assessment
October 21, 2025

Study of Biological Diversity Effects of Pesticide Mixtures Highlights Underestimated Risks to Ecosystems
September 17, 2025

Eighty Pesticides Detected in the Air of Rural Agricultural Area
August 8, 2025

Widely Used Fungicide Mixed with Natural Mycotoxins Increases Toxicity of Treated Food Crops
April 18, 2025

Microplastics Interact with Pesticides, Exacerbating Environmental Health Threats, Studies Find
February 25, 2025

Studies Cite Risk Assessment and Regulatory Deficiencies in Protecting Ground-Nesting Bees
December 3, 2024

Study Highlights Correlation Between Pesticide Exposure and Prostate Cancer in Men in the U.S.
November 19, 2024

Flooding Transports Pesticides from Streams to Soil and Plants, Threatens Terrestrial Food Webs
October 22, 2024

Over 60 Biomarkers of Pollutants and Pesticides Found in Hair Analyses of French Children
August 7, 2024

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Azoxystrobin

General Information

• Product Names:

  Abound (Syngenta)
   Amistar (Syngenta)
  Dynasty (Syngenta)
  Heritage (Syngenta)
  Quadris (Syngenta)
  Protégé (Bayer)
  Sporgard (Lanxess)
  Quilt (Syngenta) formulated with Propiconazole
  Uniform (Syngenta) formulated with Metalaxyl

• Chemical Class: beta-methoxyacrylate fungicide/antimicrobial; systemic
• Uses: Various agriculture and non-agricultural uses: fruits, vegetables, nuts, feed crops, turf, ornamentals, residential sites; additive treatment for paint, plastic, rubber, paper (textiles and adhesives); commercial/industrial sites.
• Alternatives: Organic agriculture, Organic lawn care
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Not documented
• Endocrine Disruption: Not documented
• Reproductive Effects: Not documented
• Neurotoxicity: Not documented
• Kidney/Liver Damage: Not documented
• Sensitizer/ Irritant: Yes: eye (1)
• Birth/Developmental: Not documented
• Detected in Groundwater: Yes (2)
• Potential Leacher: Yes (1, 2)
• Toxic to Birds: Not documented
• Toxic to Fish/Aquatic Organisms: Yes (1, 2)
• Toxic to Bees: Not documented

Additional Information

• Regulatory Status:
  • EPA Regulatory Documents
• Supporting information:
  • Extoxnet Pesticide Factsheet (Extension Toxicology Network)
  • PAN Pesticides Database: (Pesticide Action Network)
• Studies [compiled from the Pesticide-Induced Diseases Database]
  • Occurrence of Azoxystrobin, Propiconazole, and Selected Other Fungicides in US Streams, 2005–2006. [Battaglin, W, Sandstrom, M et al. 2010. Water Air Soil Pollution. 218 (1-4):307-322 ]
  • Occurrence, fate and effects of azoxystrobin in aquatic ecosystems: A review. [Rodrigues, ET, Lopes, I et al. 2013. Environment International 53:18–28]
  • Direct pesticide exposure of insects in nature conservation areas in Germany. Brühl, C.A., Bakanov, N., Köthe, S., Eichler, L., Sorg, M., Hörren, T., Mühlethaler, R., Meinel, G. and Lehmann, G.U. Scientific reports, 11(1), pp.1-10.
  • Bees under interactive stressors: the novel insecticides flupyradifurone and sulfoxaflor along with the fungicide azoxystrobin disrupt the gut microbiota of honey bees and increase opportunistic bacterial pathogens. Al Naggar, Y., Singavarapu, B., Paxton, R.J. and Wubet, T., 2022. Science of The Total Environment, 849, p.157941.
  • Single and combined exposure to ‘bee safe’ pesticides alter behaviour and offspring production in a ground-nesting solitary bee (Xenoglossa pruinosa). Rondeau, S. and Raine, N. (2024) Single and combined exposure to ‘bee safe’ pesticides alter behaviour and offspring production in a ground-nesting solitary bee (Xenoglossa pruinosa), Proceedings of the Royal Society Biological Sciences. Available at: https://royalsocietypublishing.org/doi/10.1098/rspb.2023.2939.
  • Exposure to pesticides, persistent and non − persistent pollutants in French 3.5-year-old children: Findings from comprehensive hair analysis in the ELFE national birth cohort. Macheka, L. et al. (2024) Exposure to pesticides, persistent and non − persistent pollutants in French 3.5-year-old children: Findings from comprehensive hair analysis in the ELFE national birth cohort, Environment International. Available at: https://www.sciencedirect.com/science/article/pii/S0160412024004677.
  • Flooding as a Vector for the Transport of Pesticides from Streams to Riparian Plants. Fiolka, F. et al. (2024) Flooding as a Vector for the Transport of Pesticides from Streams to Riparian Plants, American Chemical Society ES&T Water. Available at: https://pubs.acs.org/doi/abs/10.1021/acsestwater.4c00571.
  • Pesticides and prostate cancer incidence and mortality: An environment-wide association study. Soerensen, S. et al. (2024) Pesticides and prostate cancer incidence and mortality: An environment-wide association study, Cancer. Available at: https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.35572.
  • Immune response of Brazilian farmers exposed to multiple pesticides . Jacobsen-Pereira, C.H. et al. (2020) ‘Immune response of Brazilian farmers exposed to multiple pesticides’, Ecotoxicology and Environmental Safety, 202, p. 110912. doi:10.1016/j.ecoenv.2020.110912.
  • A Th2-type immune response and low-grade systemic inflammatory reaction as potential immunotoxic effects in intensive agriculture farmers exposed to pesticides . Lozano-Paniagua, D. et al. (2024) ‘A th2-type immune response and low-grade systemic inflammatory reaction as potential immunotoxic effects in intensive agriculture farmers exposed to pesticides’, Science of The Total Environment, 938, p. 173545. doi:10.1016/j.scitotenv.2024.173545.
  • Assessing the Presence of Current-Use Pesticides in Mid-Elevation Sierra Nevada Streams Using Passive Samplers, California, 2018–19. De Parsia, M.D., Orlando, J.L., and Hladik, M.L., 2023, Assessing the presence of current-use pesticides in mid-elevation Sierra Nevada streams using passive samplers, California, 2018–19: U.S. Geological Survey Scientific Investigations Report 2022–5129, 31 p., https://doi.org/10.3133/sir20225129.
  • Effects of Microplastics on the Adsorption and Bioavailability of Three Strobilurin Fungicides. Hai, N., Liu, X., Li, Y., Kong, F., Zhang, Y., & Fang, S. (2020). Effects of Microplastics on the Adsorption and Bioavailability of Three Strobilurin Fungicides. ACS omega, 5(47), 30679–30686. https://doi.org/10.1021/acsomega.0c04787
  • Different effects of polyethylene microplastics on bioaccumulation of three fungicides in maize (Zea mays L.). Qiu, S., Shen, H., Song, J. et al. Different effects of polyethylene microplastics on bioaccumulation of three fungicides in maize (Zea mays L.). Crop Health 2, 7 (2024). https://doi.org/10.1007/s44297-024-00028-x
  • The influence of polyethylene microplastics on pesticide residue and degradation in the aquatic environment. Wang, F., Gao, J., Zhai, W., Liu, D., Zhou, Z., & Wang, P. (2020). The influence of polyethylene microplastics on pesticide residue and degradation in the aquatic environment. Journal of hazardous materials, 394, 122517. https://doi.org/10.1016/j.jhazmat.2020.122517
  • Intensive vegetable production under plastic mulch: A field study on soil plastic and pesticide residues and their effects on the soil microbiome. Beriot, N., Zornoza, R., Lwanga, E. H., Zomer, P., van Schothorst, B., Ozbolat, O., Lloret, E., Ortega, R., Miralles, I., Harkes, P., van Steenbrugge, J., & Geissen, V. (2023). Intensive vegetable production under plastic mulch: A field study on soil plastic and pesticide residues and their effects on the soil microbiome. The Science of the total environment, 900, 165179. https://doi.org/10.1016/j.scitotenv.2023.165179
  • Pesticide effects on nitrogen cycle related microbial functions and community composition. Sim, J. X. F., Doolette, C. L., Vasileiadis, S., Drigo, B., Wyrsch, E. R., Djordjevic, S. P., Donner, E., Karpouzas, D. G., & Lombi, E. (2022). Pesticide effects on nitrogen cycle related microbial functions and community composition. The Science of the total environment, 807(Pt 1), 150734. https://doi.org/10.1016/j.scitotenv.2021.150734
  • Fate of pesticide residues in beer and its by-products. Hakme, E., Kallehauge Nielsen, I., Fermina Madsen, J., Storkehave, L. M., Skjold Elmelund Pedersen, M., Schulz, B. L., … Duedahl-Olesen, L. (2023). Fate of pesticide residues in beer and its by-products. Food Additives & Contaminants: Part A, 41(1), 45–59. https://doi.org/10.1080/19440049.2023.2282557
  • Combined Cytotoxic Effects of the Fungicide Azoxystrobin and Common Food-Contaminating Mycotoxins. Fuentes, C. et al. (2025) Combined Cytotoxic Effects of the Fungicide Azoxystrobin and Common Food-Contaminating Mycotoxins, Foods. Available at: https://www.mdpi.com/2304-8158/14/7/1226.
  • Azoxystrobin Induces Apoptosis of Human Esophageal Squamous Cell Carcinoma KYSE-150 Cells through Triggering of the Mitochondrial Pathway. Shi, X. K., Bian, X. B., Huang, T., Wen, B., Zhao, L., Mu, H. X., Fatima, S., Fan, B. M., Bian, Z. X., Huang, L. F., & Lin, C. Y. (2017). Azoxystrobin Induces Apoptosis of Human Esophageal Squamous Cell Carcinoma KYSE-150 Cells through Triggering of the Mitochondrial Pathway. Frontiers in pharmacology, 8, 277. https://doi.org/10.3389/fphar.2017.00277
  • Fungicide and insecticide exposure adversely impacts bumblebees and pollination services under semi-field conditions. Tamburini, G., Pereira-Peixoto, M. H., Borth, J., Lotz, S., Wintermantel, D., Allan, M. J., Dean, R., Schwarz, J. M., Knauer, A., Albrecht, M., & Klein, A. M. (2021). Fungicide and insecticide exposure adversely impacts bumblebees and pollination services under semi-field conditions. Environment international, 157, 106813. https://doi.org/10.1016/j.envint.2021.106813
  • Pesticide residues in fresh fruits imported into the United Arab Emirates. Osaili, Tareq & Sallagi, Maryam & Kumar, Dinesh & Odeh, Wael & Ali, Hajer & Ali, Ahmed & Cheikh Ismail, Leila & Mehri, Khadija & Pisharath, Vijayan & Holley, Richard & Shaker Obaid, Reyad. (2022). Pesticide residues in fresh fruits imported into the United Arab Emirates. Heliyon. 8. e11946. 10.1016/j.heliyon.2022.e11946.
  • Monitoring of Non-Maximum-Residue-Level Pesticides in Animal Feed: A Study from 2019 to 2023. Giugliano, R., Armenio, V., Savio, V., Vaccaro, E., Ciccotelli, V., & Vivaldi, B. (2024). Monitoring of Non-Maximum-Residue-Level Pesticides in Animal Feed: A Study from 2019 to 2023. Toxics, 12(9), 680. https://doi.org/10.3390/toxics12090680
  • Occurrence of Current-Use Pesticides in Paired Indoor Dust, Drinking Water, and Urine Samples from the United States: Risk Prioritization and Health Implications. Xie, Y., Li, J., Salamova, A., & Zheng, G. (2025). Occurrence of Current-Use Pesticides in Paired Indoor Dust, Drinking Water, and Urine Samples from the United States: Risk Prioritization and Health Implications. Environmental science & technology, 59(25), 12507–12519. https://doi.org/10.1021/acs.est.5c00961
  • Pesticides in surface water of the Ondas river watershed, western Bahia, Brazil: Spatial-seasonal distribution and risk assessment. do Rego EL, de Souza JR, Nakamura TC, Portela JF, Diniz PHGD, da Silva JDS. Pesticides in surface water of the Ondas river watershed, western Bahia, Brazil: Spatial-seasonal distribution and risk assessment. Chemosphere. 2024 Apr;354:141659. doi: 10.1016/j.chemosphere.2024.141659. Epub 2024 Mar 13. PMID: 38490616.
  • Synergistic Pesticide Effects on Complex Arthropod Trophic Interactions in Arable Systems. Woodcock, B. et al. (2025) Synergistic Pesticide Effects on Complex Arthropod Trophic Interactions in Arable Systems, Environmental Science & Technology. Available at: https://pubs.acs.org/doi/abs/10.1021/acs.est.5c04611.
  • Characterization of aggregated exposure to multiple pesticides near agricultural fields: an application of silicone wristbands. Ottenbros, Ilse & Vermeulen, R & Krop, E & Beeltje, Henry & Fuhrimann, Samuel & Figueiredo, Daniel. (2025). Characterization of aggregated exposure to multiple pesticides near agricultural fields: an application of silicone wristbands. Environmental Research Communications. 7. 10.1088/2515-7620/adc547.
  • Pesticides detected in two urban areas have implications for local butterfly conservation. Dittemore, C. et al. (2025) Pesticides detected in two urban areas have implications for local butterfly conservation, Environmental Toxicology and Chemistry. Available at: https://academic.oup.com/etc/advance-article-abstract/doi/10.1093/etojnl/vgaf218/8245823.
  • Combined pesticide pollution enhances the dissemination of the phage-encoded antibiotic resistome in the soil under nitrogen deposition. Shen, Luo-Qin et al. “Combined pesticide pollution enhances the dissemination of the phage-encoded antibiotic resistome in the soil under nitrogen deposition.” Proceedings of the National Academy of Sciences of the United States of America vol. 122,40 (2025): e2516722122. doi:10.1073/pnas.2516722122
  • A cumulative dietary pesticide exposure score based on produce consumption is associated with urinary pesticide biomarkers in a U.S. biomonitoring cohort. Temkin, A. et al. (2025) A cumulative dietary pesticide exposure score based on produce consumption is associated with urinary pesticide biomarkers in a U.S. biomonitoring cohort, International Journal of Hygiene and Environmental Health. Available at: https://www.sciencedirect.com/science/article/pii/S1438463925001361.
  • Mechanisms and histopathological impacts of acetamiprid and azoxystrobin in male rats. EL-Hak, H.N.G., Al-Eisa, R.A., Ryad, L. et al. Mechanisms and histopathological impacts of acetamiprid and azoxystrobin in male rats. Environ Sci Pollut Res 29, 43114–43125 (2022). https://doi.org/10.1007/s11356-021-18331-3
  • Honey bee hives as biomonitors of pesticide environmental pollution. The INSIGNIA-EU monitoring action. Fernández-Alba, A. et al. (2025) Honey bee hives as biomonitors of pesticide environmental pollution. The INSIGNIA-EU monitoring action, Science of The Total Environment. Available at: https://www.sciencedirect.com/science/article/pii/S0048969725019254.