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Allethrin

(includes all allethrin stereoisomers: d-trans allethrin, bioallethrin, S-bioallethrin, d-cis/trans allethrin)

General Information

• Product Names:

  Snake (S.C. Johnson)
  Konk (AMREP) formulated with Permethrin
  Unicorn (Phaeton) formulated with Permethrin
  Spira (Zobele)
  House & Garden Bug Killer (Celex) formulated with Permentrin
  Family Mosquito (Family Products)
  Buzz Buster (Multinational Resources)

• Chemical Class: Pyrethroid
• Uses: Wasps and hornets, roaches, ants, fleas, and mosquitos, approved for residential, horticultural non food plants, commercial animal premise (indoor) misting systems
• Alternatives: Least-Toxic Insecticide
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Not documented
• Endocrine Disruption: Yes (1)
• Reproductive Effects: Not documented
• Neurotoxicity: Yes (2, 3, 4)
• Kidney/Liver Damage: Yes (2)
• Sensitizer/ Irritant: Yes (2)
• Birth/Developmental: Not documented
• Detected in Groundwater: Not documented
• Potential Leacher: No (5)
• Toxic to Birds: No (2)
• Toxic to Fish/Aquatic Organisms: Yes (2)
• Toxic to Bees: Yes (2)

Residential Uses as Found in the ManageSafe™ Database

• Cockroaches
• Bed Bugs
• Mosquitoes
• Spiders

Additional Information

• Regulatory Status:
  • EPA Reregistration Eligibility Decision (RED) signed (6/2007)
  • EPA Amended RED (05/2009)
• Supporting information:
  • Extoxnet Pesticide Factsheet (Extension Toxicology Network)
  • PAN Pesticides Database: (Pesticide Action Network)
• Studies [compiled from the Pesticide-Induced Diseases Database]
  • Mosquito repellent (pyrethroid-based) induced dysfunction of blood–brain barrier permeability in developing brain.Sinha, C et al. 2004. International Journal of Developmental Neuroscience
  • Morphological changes in the respiratory system of mice after inhalation of mosquito-coil smoke. Cheng V, et al. 1992. Toxicology letters
  • The action of allethrin on the peripheral nervous system of the frog. Joep Van Den Bercken. 1976. Pest Management Science
  • Allethrin toxicity causes reproductive dysfunction in male rats. Madhubabu G, Yenugu S. 2017. Environ Toxicol. 32(6):1701-1710.
  • The effect of follicullar fluid pesticides and polychlorinated biphenyls concentrations on intracytoplasmic sperm injection (ICSI) embryological and clinical outcome. Al-Hussaini, T. K., Abdelaleem, A. A., Elnashar, I., Shabaan, O. M., Mostafa, R., El-Baz, M. A. H., El-Deek, S. E. M., & Farghaly, T. A. (2018). The effect of follicullar fluid pesticides and polychlorinated biphenyls concentrations on intracytoplasmic sperm injection (ICSI) embryological and clinical outcome. European journal of obstetrics, gynecology, and reproductive biology, 220, 39–43. https://doi.org/10.1016/j.ejogrb.2017.11.003
  • Acute Toxicity Study Of D-trans Allethrin And D-phenothrin To Zebrafish, Danio Rerio And Its Human Relevance. Hamid, Alif & Muhammad, Hussin & Lee, Siew Pien & Nik Hassan, Nik F. & Lokman, Isa. (2024). Acute Toxicity Study Of D-trans Allethrin And D-phenothrin To Zebrafish, Danio Rerio And Its Human Relevance. Community practitioner: the journal of the Community Practitioners' & Health Visitors' Association. 21. 243-250.