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Updates from the Daily News Blog

Pervasive Pesticide Contamination of Beehives Across Europe, the First EU-Wide Study of Its Kind
January 28, 2026

Tis the Season for Family and Friends To Think About Going Organic for Safety Reasons—Christmas Trees in Focus
December 19, 2025

Study Highlights Correlation Between Pesticide Exposure and Prostate Cancer in Men in the U.S.
November 19, 2024

Flooding Transports Pesticides from Streams to Soil and Plants, Threatens Terrestrial Food Webs
October 22, 2024

Acute Pesticide Incidents May Lead to Loss of Smell
January 23, 2019

Settlement Will Safeguard Endangered California Frog from Harmful Pesticides
November 6, 2013

Fisheries Service Tells EPA to Better Protect Endangered Species from Pesticides
April 16, 2012

Unprecedented Pesticide Contamination Found in Beehives
March 30, 2010

Herbicide Exposure Linked to Pancreatic Cancer
May 28, 2009

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Pendimethalin

General Information

• Fact Sheet: pendimethalin.pdf
• Product Names:

  Squadron (BASF) formulated with Imazaquin
  Pursuit (BASF) formulated with Imazethapyr
  Prowl (BASF)
  Pendulum (BASF)
  Pre-M (BASF)
  Steel (BASF) formulated with Imazaquin, formulated with Imazethapyr
  Turf Builder (Scotts)
  Scotts Halts (Scotts)
  Crabgrass Preventer (Scotts)
  Freehand (BASF) formulated with dimethenamide-P

  Cando (BASF) formulated with dimethenamide-P
  Aquapen (Drexel Chemical)
  Southern Weedgrass control (Everris)

• Chemical Class: Dinitroaniline herbicide
• Uses: Selective herbicide, controls broadleaf weeds and grassy weed species in agriculture and lawns.
• Alternatives: Organic agriculture, Organic lawn care
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Possible (1)
• Endocrine Disruption: Yes (2)
• Reproductive Effects: Yes (3)
• Neurotoxicity: Not documented
• Kidney/Liver Damage: Yes (4)
• Sensitizer/ Irritant: Yes (5)
• Birth/Developmental: Not documented
• Detected in Groundwater: Yes (3)
• Potential Leacher: Not documented
• Toxic to Birds: Not documented
• Toxic to Fish/Aquatic Organisms: Yes (3, 6)
• Toxic to Bees: Not documented

Residential Uses as Found in the ManageSafe™ Database

• Dandelions
• Crabgrass
• Knotweed

Additional Information

• Regulatory Status:
  • EPA Reregistration Eligibility Decision (RED) signed (4/1997)
• Supporting information:
  • Extoxnet Pendimethalin Factsheet (Extension Toxicology Network)
  • PAN Pesticides Database:Pendimethalin (Pesticide Action Network)
  • Scorecard Pendimethalin Factsheet (The Pollution Information Site)
• Studies [compiled from the Pesticide-Induced Diseases Database]
  • Agricultural pesticide use and pancreatic cancer risk in the Agricultural Health Study Cohort.. Andreotti G, Freeman LE, Hou L, Coble J, Rusiecki J, et al. 2009. Int J Cancer. 124(10):2495-500.
  • Autism: Transient in utero hypothyroxinemia related to maternal flavonoid ingestion during pregnancy and to other environmental antithyroid agents. Román, G, C. 2007. Journal of the Neurological Sciences; 262(1-2), pp 15-26
  • Exacerbation of symptoms in agricultural pesticide applicators with asthma.. Henneberger PK, Liang X, London SJ, et al.2014. Int Arch Occup Environ Health. 87(4):423-32.
  • Human exposure and risk assessment to airborne pesticides in a rural French community.. Coscollà C, López A, Yahyaoui A, Colin P, et al. 2017. Sci Total Environ. 584-585:856-868
  • In vitro genotoxicity assessment of dinitroaniline herbicides pendimethalin and trifluralin.. Kılıç, Z.S., Aydın, S., Bucurgat, Ü.Ü. and Başaran, N., 2018. Food and chemical toxicology, 113, pp.90-98.
  • Flooding as a Vector for the Transport of Pesticides from Streams to Riparian Plants. Fiolka, F. et al. (2024) Flooding as a Vector for the Transport of Pesticides from Streams to Riparian Plants, American Chemical Society ES&T Water. Available at: https://pubs.acs.org/doi/abs/10.1021/acsestwater.4c00571.
  • Pesticides and prostate cancer incidence and mortality: An environment-wide association study. Soerensen, S. et al. (2024) Pesticides and prostate cancer incidence and mortality: An environment-wide association study, Cancer. Available at: https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.35572.
  • Pesticide-Induced Inflammation at a Glance. Lopes-Ferreira, M. et al. (2023) ‘Pesticide-induced inflammation at a glance’, Toxics, 11(11), p. 896. doi:10.3390/toxics11110896.
  • Pesticide exposure and risk of cardiovascular disease: A systematic review. Zago, A. M., Faria, N. M. X., Fávero, J. L., Meucci, R. D., Woskie, S., & Fassa, A. G. (2022). Pesticide exposure and risk of cardiovascular disease: A systematic review. Global public health, 17(12), 3944–3966. https://doi.org/10.1080/17441692.2020.1808693
  • Physiological and oxidative stress biomarkers in the freshwater monosex Nile tilapia, Oreochromis niloticus L., exposed to pendimethalin-based herbicide. El-Sayed, Y.S., Samak, D.H., Abou-Ghanema, I.Y. and Soliman, M.K. (2015), Physiological and oxidative stress biomarkers in the freshwater monosex Nile tilapia, Oreochromis niloticus L., exposed to pendimethalin-based herbicide. Environ. Toxicol., 30: 430-438. https://doi.org/10.1002/tox.21919
  • Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review. Matich, E. K., Laryea, J. A., Seely, K. A., Stahr, S., Su, L. J., & Hsu, P. C. (2021). Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review. Ecotoxicology and environmental safety, 219, 112327. https://doi.org/10.1016/j.ecoenv.2021.112327