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Florpyrauxifen-benzyl

Updated June 2019

General Information

• Product Names:

  ProcellaCOR (SePRO)

• Chemical Class: Arylpicolinate class of herbicides; Synthetic auxin
• Uses: Systemic herbicide used on rice, post-emergence grass, sedge, and broadleaf weed control in several states and for national use to control invasive species such as hydrilla, watermilfoil, crested floating heart in freshwater aquatic sites.
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Suggestive Evidence (1)
• Endocrine Disruption: Suggestive Evidence (1)
• Reproductive Effects: Not documented
• Neurotoxicity: Not documented
• Kidney/Liver Damage: Suggestive Evidence (1)
• Sensitizer/ Irritant: Not documented
• Birth/Developmental: Not documented
• Detected in Groundwater: Not documented
• Potential Leacher: Not documented
• Toxic to Birds: Not documented
• Toxic to Fish/Aquatic Organisms: Not documented
• Toxic to Bees: Not documented

Additional Information

• Regulatory Status:
  • EPA Registration (2017)
• Supporting information:
  • EFSA Risk Assessment (2018)
• Studies [compiled from the Pesticide-Induced Diseases Database]
  • Enhanced Herbicide Metabolism and Target Site Mutation Enabled the Multiple Resistance to Cyhalofop-butyl, Florpyrauxifen-benzyl, and Penoxsulam in Echinochloa crus-galli. Yu, X. et al. (2024) Enhanced Herbicide Metabolism and Target Site Mutation Enabled the Multiple Resistance to Cyhalofop-butyl, Florpyrauxifen-benzyl, and Penoxsulam in Echinochloa crus-galli, Journal of Agricultural and Food Chemistry. Available at: https://pubs.acs.org/doi/abs/10.1021/acs.jafc.4c02450.
  • Short-term immunotoxicity induced by florpyrauxifen-benzyl herbicide exposure in the spleen of male albino mice. Morsi, D. S., Abu Quora, H. A., AboShabaan, H. S., El-Garawani, I. M., Abdel Moneim, A. E., & Hathout, H. M. R. (2024). Short-term immunotoxicity induced by florpyrauxifen-benzyl herbicide exposure in the spleen of male albino mice. Journal of experimental zoology. Part A, Ecological and integrative physiology, 341(6), 658–671. https://doi.org/10.1002/jez.2814
  • The induced hepatotoxicity and genotoxicity in Oreochromis niloticus exposed to a newly released florpyrauxifen-benzyl herbicide. Nabet, N. et al. (2025) The induced hepatotoxicity and genotoxicity in Oreochromis niloticus exposed to a newly released florpyrauxifen-benzyl herbicide, Ecotoxicology. Available at: https://link.springer.com/article/10.1007/s10646-025-02864-1.