Gateway test
Tetrachlorvinphos (TCVP)
General Information
- Product Names:
- Chemical Class: Organophosphate insecticide
- Uses: Fleas, ticks, various flies, lice, and insect larvae on livestock and pets and their premises. Also applied as a perimeter treatment.
- Beyond Pesticides rating: Toxic
Health and Environmental Effects
- Cancer: Yes (1, 2)
- Endocrine Disruption: Not documented
- Reproductive Effects: Not documented
- Neurotoxicity: Yes (1)
- Kidney/Liver Damage: Yes (1)
- Sensitizer/ Irritant: Not documented
- Birth/Developmental: Not documented
- Detected in Groundwater: Not documented
- Potential Leacher: Not documented
- Toxic to Birds: Not documented
- Toxic to Fish/Aquatic Organisms: Yes (1)
- Toxic to Bees: Yes (1)
Additional Information
- Regulatory Status:
- Supporting information:
- Studies [compiled from the Pesticide-Induced Diseases Database]
- Temporal trends of agricultural organophosphate pesticide use in California and proximity to pregnant people in 2021. Rotkin-Ellman, M., Carpenter, C., Richardson, M.J. et al. Temporal trends of agricultural organophosphate pesticide use in California and proximity to pregnant people in 2021. BMC Public Health 25, 3121 (2025). https://doi.org/10.1186/s12889-025-23939-y
- Pre-conceptional and prenatal exposure to pesticides and pediatric neuroblastoma. A meta-analysis of nine studies. Khan, A., Feulefack, J., & Sergi, C. M. (2022). Pre-conceptional and prenatal exposure to pesticides and pediatric neuroblastoma. A meta-analysis of nine studies. Environmental toxicology and pharmacology, 90, 103790. https://doi.org/10.1016/j.etap.2021.103790
- Parental Pesticide Exposure and Childhood Brain Cancer: A Systematic Review and Meta-Analysis Confirming the IARC/WHO Monographs on Some Organophosphate Insecticides and Herbicides. Feulefack, J., Khan, A., Forastiere, F., & Sergi, C. M. (2021). Parental Pesticide Exposure and Childhood Brain Cancer: A Systematic Review and Meta-Analysis Confirming the IARC/WHO Monographs on Some Organophosphate Insecticides and Herbicides. Children (Basel, Switzerland), 8(12), 1096. https://doi.org/10.3390/children8121096
Gateway Health and Environmental Effects Citations
1. US EPA, Office of Prevention, Pesticides and Toxic Substances, Reregistration Eligibility Decisions (REDs), Interim REDS (iREDs) and RED Factsheets. https://archive.epa.gov/pesticides/reregistration/web/html/status.html.
2. California Environmental Protection Agency. Proposition 65: Chemicals Known to the State to Cause Cancer or Reproductive Toxicity. Office of Environmental Health Hazard Assessment. February 25, 2022.https://oehha.ca.gov/media/downloads/proposition-65//p65chemicalslistsinglelisttable2021p.pdf








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