Gateway test
Spiroxamine
General Information
- Product Names:
- Chemical Class: Fungicide
- Beyond Pesticides rating: Toxic
Health and Environmental Effects
- Cancer: Not documented
- Endocrine Disruption: Not documented
- Reproductive Effects: Yes (1)
- Neurotoxicity: Not documented
- Kidney/Liver Damage: Not documented
- Sensitizer/ Irritant: Yes (1)
- Birth/Developmental: Not documented
- Detected in Groundwater: Not documented
- Potential Leacher: Not documented
- Toxic to Birds: Yes (1)
- Toxic to Fish/Aquatic Organisms: Yes (1)
- Toxic to Bees: Yes (1)
Additional Information
- Regulatory Status:
- EPA Registration Eligibility Decision signed (Jan/2004)
- Supporting information:
- PAN Pesticides Database: Spiroxamine (Pesticide Action Network)
- Studies [compiled from the Pesticide-Induced Diseases Database]
- Flooding as a Vector for the Transport of Pesticides from Streams to Riparian Plants. Fiolka, F. et al. (2024) Flooding as a Vector for the Transport of Pesticides from Streams to Riparian Plants, American Chemical Society ES&T Water. Available at: https://pubs.acs.org/doi/abs/10.1021/acsestwater.4c00571.
- Current-use pesticides in vegetation, topsoil and water reveal contaminated landscapes of the Upper Rhine Valley, Germany. Mauser, K.M., Wolfram, J., Spaak, J.W. et al. Current-use pesticides in vegetation, topsoil and water reveal contaminated landscapes of the Upper Rhine Valley, Germany. Commun Earth Environ 6, 166 (2025). https://doi.org/10.1038/s43247-025-02118-2
- Assessing pesticide residue occurrence and risks in the environment across Europe and Argentina. Alaoui, A., Christ, F., Abrantes, N., Silva, V., González, N., Gai, L., Harkes, P., Navarro, I., Torre, A., Martínez, M. Á., Norgaard, T., Vested, A., Schlünssen, V., Aparicio, V. C., Campos, I., Pasković, I., Pasković, M. P., Glavan, M., Ritsema, C., & Geissen, V. (2024). Assessing pesticide residue occurrence and risks in the environment across Europe and Argentina. Environmental pollution (Barking, Essex : 1987), 363(Pt 1), 125056. https://doi.org/10.1016/j.envpol.2024.125056
- Fate of pesticide residues in beer and its by-products. Hakme, E., Kallehauge Nielsen, I., Fermina Madsen, J., Storkehave, L. M., Skjold Elmelund Pedersen, M., Schulz, B. L., … Duedahl-Olesen, L. (2023). Fate of pesticide residues in beer and its by-products. Food Additives & Contaminants: Part A, 41(1), 45–59. https://doi.org/10.1080/19440049.2023.2282557
- Widespread Pesticide Distribution in the European Atmosphere Questions their Degradability in Air. Mayer, L., Degrendele, C., Šenk, P., Kohoutek, J., Přibylová, P., Kukučka, P., Melymuk, L., Durand, A., Ravier, S., Alastuey, A., Baker, A. R., Baltensperger, U., Baumann-Stanzer, K., Biermann, T., Bohlin-Nizzetto, P., Ceburnis, D., Conil, S., Couret, C., Degórska, A., Diapouli, E., … Lammel, G. (2024). Widespread Pesticide Distribution in the European Atmosphere Questions their Degradability in Air. Environmental science & technology, 58(7), 3342–3352. Advance online publication. https://doi.org/10.1021/acs.est.3c08488
Gateway Health and Environmental Effects Citations
1. US EPA, Office of Prevention, Pesticides and Toxic Substances, Reregistration Eligibility Decisions (REDs), Interim REDS (iREDs) and RED Factsheets. https://archive.epa.gov/pesticides/reregistration/web/html/status.html.








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