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Pymetrozine

General Information

• Product Names:

  Fulfill (Syngenta)
  Endeavor (Syngenta)

• Chemical Class: Pyridine azomethines
• Uses: Control whiteflies and aphids
• Alternatives: Organic agriculture
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Likely (1)
• Endocrine Disruption: No
• Reproductive Effects: Yes (1)
• Neurotoxicity: Yes (1)
• Kidney/Liver Damage: Yes (1)
• Sensitizer/ Irritant: Yes (1)
• Birth/Developmental: Yes (1)
• Detected in Groundwater: Not documented
• Potential Leacher: Not documented
• Toxic to Birds: Not documented
• Toxic to Fish/Aquatic Organisms: Not documented
• Toxic to Bees: Not documented

Additional Information

• Regulatory Status:
  • EPA Factsheet (2000)
• Supporting information:
  • PAN Pesticides Database: Pymetrozine
• Studies [compiled from the Pesticide-Induced Diseases Database]
  • Immune response of Brazilian farmers exposed to multiple pesticides . Jacobsen-Pereira, C.H. et al. (2020) ‘Immune response of Brazilian farmers exposed to multiple pesticides’, Ecotoxicology and Environmental Safety, 202, p. 110912. doi:10.1016/j.ecoenv.2020.110912.
  • Lethal, sublethal, and combined effects of pesticides on bees: A meta-analysis and new risk assessment tools. Tosi, S., Sfeir, C., Carnesecchi, E., vanEngelsdorp, D., & Chauzat, M. P. (2022). Lethal, sublethal, and combined effects of pesticides on bees: A meta-analysis and new risk assessment tools. The Science of the total environment, 844, 156857. https://doi.org/10.1016/j.scitotenv.2022.156857
  • Characterization of aggregated exposure to multiple pesticides near agricultural fields: an application of silicone wristbands. Ottenbros, Ilse & Vermeulen, R & Krop, E & Beeltje, Henry & Fuhrimann, Samuel & Figueiredo, Daniel. (2025). Characterization of aggregated exposure to multiple pesticides near agricultural fields: an application of silicone wristbands. Environmental Research Communications. 7. 10.1088/2515-7620/adc547.