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Gateway test
Methidathion
General Information
- Product Names:
- Chemical Class: Organophosphate insecticide
- Uses: Almonds, apples, apricots, artichokes, carambola, cherries, cotton, grapefruit, kiwifruit, lemons, longan, mandarin, mango, nectarines, olives, oranges, peaches, pears, pecans, plums and prunes, safflower, sugar apple, sunflower and walnuts, alfalfa and clover seed, grass hay, tobacco, and ornamental plants and shrubs for broad control of insects.
- Alternatives: Organic agriculture
- Beyond Pesticides rating: Toxic
Health and Environmental Effects
- Cancer: Possible (1)
- Endocrine Disruption: Not documented
- Reproductive Effects: Not documented
- Neurotoxicity: Yes (1)
- Kidney/Liver Damage: Not documented
- Sensitizer/ Irritant: Yes (2)
- Birth/Developmental: Not documented
- Detected in Groundwater: Not documented
- Potential Leacher: Not documented
- Toxic to Birds: Yes (1)
- Toxic to Fish/Aquatic Organisms: Yes (1)
- Toxic to Bees: Yes (1)
Additional Information
- Regulatory Status:
- Cancellation Order for Pesticide Registrations: Methidathion (6/2010)
- EPA Reregistration Eligibility Decision (RED) signed (7/2006)
- Supporting information:
- Extoxnet Methidathion Factsheet (Extension Toxicology Network)
- PAN Pesticides Database - Methidation (Pesticide Action Network)
- Studies [compiled from the Pesticide-Induced Diseases Database]
- Temporal trends of agricultural organophosphate pesticide use in California and proximity to pregnant people in 2021. Rotkin-Ellman, M., Carpenter, C., Richardson, M.J. et al. Temporal trends of agricultural organophosphate pesticide use in California and proximity to pregnant people in 2021. BMC Public Health 25, 3121 (2025). https://doi.org/10.1186/s12889-025-23939-y
Gateway Health and Environmental Effects Citations
1. US EPA, Office of Prevention, Pesticides and Toxic Substances, Reregistration Eligibility Decisions (REDs), Interim REDS (iREDs) and RED Factsheets. https://archive.epa.gov/pesticides/reregistration/web/html/status.html.
2. Extension Toxicology Network (EXTOXNET) Pesticide Information Profiles. http://extoxnet.orst.edu/pips/ghindex.html