Gateway test
Formetanate hydrochloride
General Information
- Product Names:
- Chemical Class: Carbamate insecticide/ miticide
- Uses: Alfalfa grown for seed, apples, pears, nectarines, peaches, grapefruit, lemon, lime, orange, tangelo, and tangerine
- Alternatives: Organic agriculture
- Beyond Pesticides rating: Toxic
Health and Environmental Effects
- Cancer: Not documented
- Endocrine Disruption: Not documented
- Reproductive Effects: Not documented
- Neurotoxicity: Yes (1)
- Kidney/Liver Damage: Not documented
- Sensitizer/ Irritant: Yes (1)
- Birth/Developmental: Not documented
- Detected in Groundwater: Not documented
- Potential Leacher: Not documented
- Toxic to Birds: Yes (1)
- Toxic to Fish/Aquatic Organisms: Yes (1)
- Toxic to Bees: Not documented
Additional Information
- Regulatory Status:
- Reregistration Eligibility Decision (RED) signed 9/2007
- Supporting information:
- PAN Pesticides Database: (Pesticide Action Network)
- Studies [compiled from the Pesticide-Induced Diseases Database]
- Pre-Conception And First Trimester Exposure To Pesticides And Associations With Stillbirth. Furlong, M. et al. (2024) Pre-conception and first trimester exposure to pesticides and associations with stillbirth, American Journal of Epidemiology. Available at: https://academic.oup.com/aje/advance-article-abstract/doi/10.1093/aje/kwae198/7714541.
- Residential proximity to agricultural pesticide exposures during preconception and pregnancy and associations with Apgar scores in the Az-PEAR study (2006–2020). Yang, A. et al. (2026) Residential proximity to agricultural pesticide exposures during preconception and pregnancy and associations with Apgar scores in the Az-PEAR study (2006–2020), Journal of Exposure Science & Environmental Epidemiology. Available at: https://www.nature.com/articles/s41370-026-00849-8.
- Preconception and first trimester exposure to pesticides and associations with stillbirth. Furlong, M. A., Paul, K. C., Parra, K. L., Fournier, A. J., Ellsworth, P. C., Cockburn, M. G., Arellano, A. F., Bedrick, E. J., Beamer, P. I., & Ritz, B. (2025). Preconception and first trimester exposure to pesticides and associations with stillbirth. American journal of epidemiology, 194(1), 44–55. https://doi.org/10.1093/aje/kwae198
Gateway Health and Environmental Effects Citations
1. US EPA, Office of Prevention, Pesticides and Toxic Substances, Reregistration Eligibility Decisions (REDs), Interim REDS (iREDs) and RED Factsheets. https://archive.epa.gov/pesticides/reregistration/web/html/status.html.








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