Gateway test
Dicofol
General Information
- Product Names:
- Chemical Class: organochlorine insecticide (miticide)
- Uses: Agriculture, Lawns/Ornamentals (non-residential)
- Alternatives: Organic Agriculture
- Beyond Pesticides rating: Toxic
Health and Environmental Effects
- Cancer: Possible (1)
- Endocrine Disruption: Potential (1), Yes (2)
- Reproductive Effects: Yes (1, 3)
- Neurotoxicity: Yes (1)
- Kidney/Liver Damage: Yes (1)
- Sensitizer/ Irritant: Yes (1)
- Birth/Developmental: Not documented
- Detected in Groundwater: Not documented
- Potential Leacher: Not documented
- Toxic to Birds: Yes (4)
- Toxic to Fish/Aquatic Organisms: Not documented
- Toxic to Bees: Not documented
Additional Information
- Regulatory Status:
- EPA Reregistration Eligibility Decision (RED) signed (9/1998)
- Supporting information:
- Extoxnet Pesticide Factsheet (Extension Toxicology Network)
- PAN Pesticides Database: (Pesticide Action Network)
- Studies [compiled from the Pesticide-Induced Diseases Database]
- Effects of a mixture of pesticides on the adult female reproductive system of Sprague-Dawley, Wistar, and Lewis rats. Pascotto VM, Guerra MT, Franci JA, et al. 2015. J Toxicol Environ Health A. 78(9):602-16
- A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides. Paul, K.C., Krolewski, R.C., Lucumi Moreno, E., Blank, J., Holton, K.M., Ahfeldt, T., Furlong, M., Yu, Y., Cockburn, M., Thompson, L.K. and Kreymerman, A., 2023. Nature Communications, 14(1), p.2803.
Gateway Health and Environmental Effects Citations
1. US EPA, Office of Prevention, Pesticides and Toxic Substances, Reregistration Eligibility Decisions (REDs), Interim REDS (iREDs) and RED Factsheets. https://archive.epa.gov/pesticides/reregistration/web/html/status.html.
2. European Commission. Endocrine Disruptors: Study on Gathering Information on 435 Substances with Insufficient Data. Final Report. EU DG Environment: B4-3040/2001/325850/MAR/C2. BKH Consulting Engineers: M0355037. November 2002. http://ec.europa.eu/environment/chemicals/endocrine/pdf/bkh_report.pdf#page=76.
3. Extension Toxicology Network (EXTOXNET) Pesticide Information Profiles. http://extoxnet.orst.edu/pips/ghindex.html
4. Mineau, P., A. Baril, B.T. Collins , J. Duffe, G. Joerman, R. Luttik. 2001. Reference values for comparing the acute toxicity of pesticides to birds. Reviews of Environmental Contamination and Toxicology 170:13-74. http://web.archive.org/web/20081006213641/http://www.abcbirds.org/abcprograms/policy/pesticides/aims/aims/toxicitytable.cfm








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