Gateway test
Chlorfenapyr
General Information
- Product Names:
- Chemical Class: Pyrrole Insecticide, Miticide
- Uses: Ornamental crops: to control mites, caterpillar pests, thrips, and fungus gnats in greenhouses
Fruits, vegetables, grains, herbs, spices, and tea: as an insecticide-miticide - Alternatives: Organic Agriculture, Organic lawn care
- Beyond Pesticides rating: Toxic
Health and Environmental Effects
- Cancer: Potential (1)
- Endocrine Disruption: Potential (1)
- Reproductive Effects: Not documented
- Neurotoxicity: Not documented
- Kidney/Liver Damage: Yes (2)
- Sensitizer/ Irritant: Not documented
- Birth/Developmental: Not documented
- Detected in Groundwater: Not documented
- Potential Leacher: Not documented
- Toxic to Birds: Yes (2)
- Toxic to Fish/Aquatic Organisms: Yes (2)
- Toxic to Bees: Yes (3)
Residential Uses as Found in the ManageSafe™ Database
Additional Information
- Regulatory Status:
- EPA Factsheet (1/2001)
- Supporting information:
- PAN Pesticides Database: (Pesticide Action Network)
- Studies [compiled from the Pesticide-Induced Diseases Database]
- Evaluation of estrogenic activities of pesticides using an in vitro reporter gene assay. Kojima M, et al 2005. Int J Environ Health Res.
- A patient fatality following the ingestion of a small amount of chlorfenapyr. Kang, C. et al. (2014) A patient fatality following the ingestion of a small amount of Chlorfenapyr, Journal of Emergencies, Trauma, and Shock. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126128/.
- Bioaccumulation, Metabolism and the Toxic Effects of Chlorfenapyr in Zebrafish (Danio rerio). Chen, X. et al. (2021) Bioaccumulation, Metabolism and the Toxic Effects of Chlorfenapyr in Zebrafish (Danio rerio), J. Agric. Food Chem. Available at: https://pubs.acs.org/doi/10.1021/acs.jafc.1c02301.
- Clinical and radiological findings in chlorfenapyr poisoning. Tharaknath, V.R. et al. (2013) Clinical and radiological findings in chlorfenapyr poisoning, Annals of Indian Academy of Neurology. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724086/.
- Chlorfenapyr poisoning: mechanisms, clinical presentations, and treatment strategies. Cheng, J. et al. (2024) Chlorfenapyr poisoning: Mechanisms, clinical presentations, and treatment strategies, World Journal of Emergency Medicine. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11153369/.
- Pesticide-Induced Inflammation at a Glance. Lopes-Ferreira, M. et al. (2023) ‘Pesticide-induced inflammation at a glance’, Toxics, 11(11), p. 896. doi:10.3390/toxics11110896.
- Assessment of genetic damage levels in agricultural workers exposed to pesticides in Paraíba, Brazil. Carvalho-Gonçalves, L. et al. (2025) Assessment of genetic damage levels in agricultural workers exposed to pesticides in Paraíba, Brazil, Environmental Toxicology and Pharmacology. Available at: https://www.sciencedirect.com/science/article/abs/pii/S1382668925000900.
- Effect of Pesticides on Adult Rove Beetle Atheta coriaria (Coleoptera: Staphylinidae) Survival in Growing Medium. Raymond A. Cloyd, Nicholas R. Timmons, Jessica M. Goebel, Kenneth E. Kemp, Effect of Pesticides on Adult Rove Beetle Atheta coriaria (Coleoptera: Staphylinidae) Survival in Growing Medium, Journal of Economic Entomology, Volume 102, Issue 5, 1 October 2009, Pages 1750–1758, https://doi.org/10.1603/029.102.0504
Gateway Health and Environmental Effects Citations
1. Hazardous Substances Data Bank (HSDB). National Center for Biotechnology Information. PubChem Compound Database. Available at: https://pubchem.ncbi.nlm.nih.gov/source/hsdb/7464.
2. U.S. EPA, Office of Prevention, Pesticides and Toxic Substances, New Active Ingredients Factsheets:
http://web.archive.org/web/20120107215849/http://www.epa.gov/opprd001/factsheets/index.htm
3. Yueh, MF et al. 2014. The commonly used antimicrobial additive triclosan is a liver tumor promoter. PNAS doi: 10.1073/pnas.141911911. Triclosan promotes liver cancer cell development and proliferation in mice through pathways common to humans.








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