Gateway test
Fluvalinate
General Information
- Fact Sheet: Fluvalinate.pdf
- Product Names:
- Chemical Class: Synthetic pyrethroid insecticide
- Uses: Non-food agriculture, ornamentals
- Alternatives: Organic agriculture, Organic lawn care
- Beyond Pesticides rating: Toxic
Health and Environmental Effects
- Cancer: Not documented
- Endocrine Disruption: Not documented
- Reproductive Effects: Yes (1)
- Neurotoxicity: Not documented
- Kidney/Liver Damage: Yes (2)
- Sensitizer/ Irritant: Yes (2)
- Birth/Developmental: Yes (3)
- Detected in Groundwater: Not documented
- Potential Leacher: Not documented
- Toxic to Birds: Not documented
- Toxic to Fish/Aquatic Organisms: Yes (2)
- Toxic to Bees: Yes (4)
Residential Uses as Found in the ManageSafe™ Database
Additional Information
- Regulatory Status:
- Supporting information:
- Daily News Blog entries (Beyond Pesticides)
- Asthma, Children and Pesticides (Beyond Pesticides)
- Children & Lawn Chemicals Don't Mix (Beyond Pesticides)
- The Safer Choice (Beyond Pesticides)
- Extoxnet Fluvalinate Factsheet (Extension Toxicology Network)
- PAN Pesticides Database:Fluvalinate (Pesticide Action Network)
- Scorecard Fluvalinate Factsheet (Environmental Defense Fund)
- FAN Fluvalinate Factsheet (Flouride Action Network)
- Studies [compiled from the Pesticide-Induced Diseases Database]
- The molecular determinants of pesticide sensitivity in bee pollinators. Bass, C. et al (2024) The molecular determinants of pesticide sensitivity in bee pollinators, Science of The Total Environment. Available at: https://www.sciencedirect.com/science/article/pii/S0048969724003097.
- Lethal, sublethal, and combined effects of pesticides on bees: A meta-analysis and new risk assessment tools. Tosi, S., Sfeir, C., Carnesecchi, E., vanEngelsdorp, D., & Chauzat, M. P. (2022). Lethal, sublethal, and combined effects of pesticides on bees: A meta-analysis and new risk assessment tools. The Science of the total environment, 844, 156857. https://doi.org/10.1016/j.scitotenv.2022.156857
- Honey bee (Apis mellifera) gut microbiota promotes host endogenous detoxification capability via regulation of P450 gene expression in the digestive tract. Wu, Y., Zheng, Y., Chen, Y., Wang, S., Chen, Y., Hu, F., & Zheng, H. (2020). Honey bee (Apis mellifera) gut microbiota promotes host endogenous detoxification capability via regulation of P450 gene expression in the digestive tract. Microbial biotechnology, 13(4), 1201–1212. https://doi.org/10.1111/1751-7915.13579
- Chronic oral lethal and sub-lethal toxicities of different binary mixtures of pesticides and contaminants in bees (Apis mellifera, Osmia bicornis and Bombus terrestris). Spurgeon, David & Hesketh, Helen & Lahive, Elma & Svendsen, Claus & Baas, Jan & Robinson, Alex & Horton, Alice & Heard, Matthew. (2016). Chronic oral lethal and sub‐lethal toxicities of different binary mixtures of pesticides and contaminants in bees (Apis mellifera, Osmia bicornis and Bombus terrestris). EFSA Supporting Publications. 13. 10.2903/sp.efsa.2016.EN-1076.
Gateway Health and Environmental Effects Citations
1. US EPA, 2000. Table 1: Toxicity Data by Category for Chemicals Listed under EPCRA Section 313. Toxic Release Inventory (TRI) Program. https://www.epa.gov/sites/production/files/documents/hazard_categories.pdf
2. Extension Toxicology Network (EXTOXNET) Pesticide Information Profiles. http://extoxnet.orst.edu/pips/ghindex.html
3. California Environmental Protection Agency. Proposition 65: Chemicals Known to the State to Cause Cancer or Reproductive Toxicity. Office of Environmental Health Hazard Assessment. February 25, 2022.https://oehha.ca.gov/media/downloads/proposition-65//p65chemicalslistsinglelisttable2021p.pdf
4. Yueh, MF et al. 2014. The commonly used antimicrobial additive triclosan is a liver tumor promoter. PNAS doi: 10.1073/pnas.141911911. Triclosan promotes liver cancer cell development and proliferation in mice through pathways common to humans.








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