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Fenvalerate

General Information

• Fact Sheet: Fenvalerate.pdf
• Product Names:

  Ortho Roach, Ant and Spider Killer (Monsanto), formulated with Petroleum distillates
  Champion SprayOn Indoor Insect Fogger Formula 4 (Chase Products), formulated with N-Octyl bicycloheptene dicarboximide, Tetramethrin
  Outdoor Ornamental Spray (Whitmere Micro-Gen Research Labs), formulated with Piperonyl Butoxide,Tetramethrin
  Insect House Spray (Scotts Company) 
  Cinch Bug Control (Scotts Company) 

• Chemical Class: Synthetic pyrethroid insecticide
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Not documented
• Endocrine Disruption: Yes (1)
• Reproductive Effects: Not documented
• Neurotoxicity: Yes (2)
• Kidney/Liver Damage: Yes (2)
• Sensitizer/ Irritant: Yes (3)
• Birth/Developmental: Not documented
• Detected in Groundwater: Not documented
• Potential Leacher: Not documented
• Toxic to Birds: Not documented
• Toxic to Fish/Aquatic Organisms: Yes (4)
• Toxic to Bees: Yes (4)

Residential Uses as Found in the ManageSafe™ Database

• Bed Bugs

Additional Information

• Regulatory Status:
  • All registrations voluntarily cancelled (effective 7/2008)
  • import tolerances remain
• Supporting information:
  • Asthma, Children and Pesticides (Beyond Pesticides)
  • PAN Pesticides Database:Fenvalerate (Pesticide Action Network)
  • Scorecard Fenvalerate Factsheet (Environmental Defense Fund)
• Studies [compiled from the Pesticide-Induced Diseases Database]

  Health Effects of Pesticides Used for Mosquito Control Citizens Campaign for the Environment (CCE) and Citizens
  Environmental Research Institute (CERI) 2002.

  • An endocrine-disrupting chemical, fenvalerate, induces cell cycle progression and collagen type I expression in human uterine leiomyoma and myometrial cells.. Gao X, Yu L, Castro L, Moore AB, et al. 2010. Toxicol Lett. 196(3):133-41
  • Pesticide contamination of bird species from Doñana National Park (southwestern Spain): Temporal trends (1999-2021) and reproductive impacts. Peris, A., Baos, R., Martínez, A., Sergio, F., Hiraldo, F. and Eljarrat, E., Available at SSRN 4312955.
  • Behavioral and endocrine changes induced by perinatal fenvalerate exposure in female rats. Moniz, A. C., Cruz-Casallas, P. E., Salzgeber, S. A., Varoli, F. M., Spinosa, H. S., & Bernardi, M. M. (2005). Behavioral and endocrine changes induced by perinatal fenvalerate exposure in female rats. Neurotoxicology and teratology, 27(4), 609–614. https://doi.org/10.1016/j.ntt.2005.05.005
  • In utero and lactational exposure to fenvalerate disrupts reproductive function in female rats. Guerra, M. T., de Toledo, F. C., & Kempinas, W.deG. (2011). In utero and lactational exposure to fenvalerate disrupts reproductive function in female rats. Reproductive toxicology (Elmsford, N.Y.), 32(3), 298–303. https://doi.org/10.1016/j.reprotox.2011.08.002
  • Adverse Effects of Pesticides on the Ovary: Evidence from Epidemiological and Toxicological Studies. Wang, L., Ma, X. and Liu, J. (2025) Adverse Effects of Pesticides on the Ovary: Evidence from Epidemiological and Toxicological Studies, Environment & Health. Available at: https://pubs.acs.org/doi/full/10.1021/envhealth.4c00243.
  • Occurrence of pyrethroids in the atmosphere of urban areas of Southeastern Brazil: Inhalation exposure and health risk assessment. Guida, Y., Pozo, K., Carvalho, G. O., Capella, R., Targino, A. C., Torres, J. P. M., & Meire, R. O. (2021). Occurrence of pyrethroids in the atmosphere of urban areas of Southeastern Brazil: Inhalation exposure and health risk assessment. Environmental pollution (Barking, Essex : 1987), 290, 118020. https://doi.org/10.1016/j.envpol.2021.118020
  • Pyrethroids cypermethrin, deltamethrin and fenvalerate have different effects on in vitro maturation of pig oocytes at different stages of growth. Petr, Jaroslav & Chmelíková, Eva & Žalmanová, Tereza & Tumova, Lenka & Kheilova, Katerina & Kučerová-Chrpová, V & Jílek, F. (2012). Pyrethroids cypermethrin, deltamethrin and fenvalerate have different effects on in vitro maturation of pig oocytes at different stages of growth. Animal : an international journal of animal bioscience. 7. 1-9. 10.1017/S1751731112001140.