(Beyond Pesticides, March 10, 2025) Following International Women’s Day, celebrated on March 8, 2025, the poignant findings on women, gender, and hazardous substances in a United Nations report raise critical issues of concern and cause for urgent action to phase out petrochemicals. The Report of the Special Rapporteur on the implications for human rights of the environmentally sound management and disposal of hazardous substances and wastes, by Marcos Orellana, was delivered to the 79th Session of the United Nations General Assembly in July 2024. Excerpts from the report follow: “Women make up roughly 60 to 70 per cent of the agricultural labour force in developing countries where pesticides and pesticide handling are especially poorly regulated. In Zambia, for example, two thirds of the labour force is engaged in agriculture, and 78 per cent are women farmers and peasants. Women there play a significant role in pesticide application, often without any or adequate personal protective equipment, especially during activities such as weeding, harvesting, and washing pesticide-laden clothes.” “In higher-income countries, women who do agricultural work are often poor and/or migrants; pesticides are one of many dimensions of marginalization and damage to their well-being. The European agriculture sector uses many seasonal and […]

(Beyond Pesticides, February 28, 2025) It is well established that children are more vulnerable than adults to environmental insults such as pesticides, from conception onward. Children living in agricultural areas are exposed differently from those in urban areas. A study of rural children by researchers at Mexico’s Universidad Atónoma de Nayarit compared two communities located less than a quarter of a mile from agricultural fields with one control community located more than a mile away. The study shows that children in the field-adjacent towns are clearly exposed to pesticides and are experiencing cellular distress as a result. The state of Nayarit is on the west coast of Mexico near Mazatlan. Rural children encounter aerial application, spray drift, and erosion. If their parents are agricultural workers and especially if they apply pesticides, they bring home residues on their clothes. Residential storage of pesticides and small children’s propensity to play in the dirt and put things in their mouths exacerbate their exposure. Urban children get hit by pesticides in their homes, schools, and parks. The researchers took blood and urine samples from 431 children aged six to 12 and collected questionnaires as to pesticide exposures from the parents or guardians. They assayed the […]

(Beyond Pesticides, February 20, 2025) Researchers at the University of Oregon found that the rollout of genetically engineered corn in the early 2000s, followed by exponential increases in glyphosate-based herbicides, “caused previously undocumented and unequal health costs for rural U.S. communities over the last 20 years.” Their results “suggest the introduction of GM [genetically modified] seeds and glyphosate significantly reduced average birthweight and gestational length.” The conclusions of this study emerge as fossil fuel advocates, including President Donald Trump, are mobilizing to pioneer “energy dominance” despite the market movement toward renewable energy. Just as chemical-intensive farmers and land managers continue to spray synthetic fertilizers and pesticides, a successful rollout of alternatives must rely on feeding the soil rather than the plant. Advocates continue to demand that elected officials and regulators embody the precautionary principle and scientific integrity in decision-making. Given the hostile federal climate on anything relating to holistic solutions, communities are coming together to move beyond input-dependent land management systems and adopt organic criteria of allowed and prohibited substances, mandatory public comment process, independent third-party certification, and a federal advisory board (National Organic Standards Board) consisting of farmers, environmentalists, consumers, scientists, economists, researchers, and other stakeholders, with binding recommendations […]

(Beyond Pesticides, February 7, 2025) With the strong associations established in epidemiologic studies and a dearth of evidence on the actual mechanisms by which pesticides inflict their damage on the brain, a new meta-analysis identifies studies that pesticides can overwhelm cells’ defenses against them, interfere with cell communication in the brain, and disrupt the epigenetic (gene function) regulation of gene expression. In the journal Nucleus, Bilal Ahmad Mir, PhD and colleagues at the University of Kashmir in Srinagar, India, review what is known at the molecular level about pesticides’ role in brain cancer. Brain cancer is a heavy burden for its victims and their families, and attributing a cause is, as with many diseases, fraught with difficulty. But there are strong clues: For example, farming is a known risk factor. In a 2021 meta-analysis of epidemiologic studies between 1998 and 2019, analyzed here by Beyond Pesticides, farming was associated with a 13% increase in the risk of brain cancer. For farmers whose specific exposure to pesticides was documented in the studies, the increase jumped to 20 percent. So there is some reason to point a finger at synthetic chemicals. But agricultural workers are not the only ones at risk. According […]

(Beyond Pesticides, February 4, 2025) Adopting a fully organic diet can reduce pesticide levels in urine within just two weeks “by an average of 98.6%” and facilitate faster DNA damage repair relative to a diet of food grown with chemical-intensive practices, according to findings from a randomized clinical trial published in Nutrire. The authors explain that their finding “is likely due to two main factors: the presence of compounds characteristic of [an organic] diet, which may have high levels of antioxidants that can protect DNA and also induce DNA repair [], and the absence or decrease in the incidence of pesticides in this type of diet, which are recognized for their genotoxic effects and have the ability to affect the genetic repair system of organisms [].” Public health professionals and affected families continue to sound the alarm on the unprecedented rates of chronic illnesses, many linked to pesticide exposure, as well as the urgency in developing solutions that acknowledge the connection to policies governing agriculture, nutrition policies, and public health. Background and Methodology The purpose of this study is to identify any relationships in health effects of chemical-intensive versus organic diets in a two week-period. More specifically, the authors say […]

(Beyond Pesticides, January 31, 2025) A recent cross-sectional study in Heliyon highlights the link between sleep disorders in Thai farmers and pesticide exposure. The authors find pesticide exposure as an important risk factor for sleep disorders after surveying 27,334 farmers over the age of 20 who had work experience for at least five years. The importance of sleep health is reflected both physically and mentally, as studies find “sleep deficiency increase[s] mortality and various health complications, including hypertension, obesity and type 2 diabetes, cardiovascular diseases, mood disorders, and neurodegenerative disorder.” Additional studies find that these issues are compounded when sleep health is affected by environmental factors such as pesticide exposure. (See previous Beyond Pesticides’ coverage here and here.) The researchers report: “The study found a positive association of 19 individual pesticides (twelve insecticides, two herbicides, and five fungicides). Some associations demonstrated a dose-response pattern. Additionally, the study revealed that women are at a higher risk of sleep-related issues with pesticide exposure compared to males. These results not only substantiate existing literature but also unveil several new individual pesticides that may impact sleep health.” Focusing on study participants in Thailand, which is “characterized by heavy pesticide use and minimal protective measures, […]

(Beyond Pesticides, January 10, 2025) [Beyond Pesticides grieves for those tragically harmed by the Los Angeles fires.] As the new year begins with the bleak and devastating reminder brought on by the Los Angeles fires, the nation and world are reminded once again that dramatic land management changes are necessary to address the erratic weather conditions contributing to the force and effect of the fires and the length of the fire season. This is only the most recent reminder, as Beyond Pesticides and many organizations call for an urgent end to land management practices and inputs that rely on the production and use of petrochemical pesticides and fertilizers, which contribute to the global climate crisis. Often incorrectly referred to as natural disasters, environmental disasters, including fires, floods, and severe weather events, are brought on or exacerbated by widespread reliance on disruptive chemicals, which played a role in a delayed start to the southern California rainy season, hurricane-force winds, and low humidity levels—all elevated by climate change. As organic is increasingly understood to be a climate solution, OrganicClimateNet last year launched an aggressive effort to build the base of organic farmers in the European Union (EU).   As the climate crisis […]

(Beyond Pesticides, December 19, 2024) As The New York Times reported last month, the government in South Africa declared a national emergency—23 children died and nearly 900 people were sickened from pesticide poisoning in Johannesburg’s Soweto township. The illnesses and fatalities have been traced to small amounts of highly neurotoxic pesticides, including the insecticides terbufos and aldicarb, found in local food items. These chemicals, described by South African President Cyril Ramaphosa as “street pesticides,” are being increasingly used (legally and illegally) for pest infestations in the townships and informal settlements of South Africa’s poorest communities, where poverty and inadequate waste collection exacerbates the pest management challenges. Without formal electricity, running water, or municipal garbage collection, many residents rely on highly toxic pesticides for pest infestations in their homes and makeshift markets, resulting in food inadvertently being contaminated with pesticides.  The announcement highlights the dangers of allowing these highly toxic agricultural chemicals to be used in farming, with tragic consequences for vulnerable communities when they are diverted for use in urban settings. This tragic situation also draws attention to the elevated threat that pesticides pose when stringent enforcement mechanisms are not in place to ensure compliance with pesticide restrictions, even with […]

(Beyond Pesticides, December 17, 2024) A systematic review of studies on pesticides as endocrine-disrupting chemicals (EDCs) on body weight, published in Biomedicines, evaluates 36 clinical and preclinical studies and links their agricultural use to obesity. The authors, with the lead researchers from the School of Medicine and Health Sciences at Catholic University of Valencia San Vincente, Valencia, Spain, assess studies on a range of pesticides, including organophosphates, pyrethroids, neonicotinoids, and others. In addition to concluding that the EDCs promote obesity, they report that the chemicals cause “other anthropometric changes by altering lipid and glucose metabolism, modifying genes, or altering hormone levels such as leptin.” Endocrine disruption and obesity are public health concerns, and there is a wide body of science linking pesticide exposure to these effects (see more here). “Obesity is considered to be a worldwide pandemic that leads to an increase in medical costs and thus becomes a public health problem,” the researchers share. They continue, “[Obesity] is also associated with the increased production of environmental chemicals, also called environmental obesogens, used mainly in agriculture, as disease vector control, helping to prevent harmful effects caused by fungi, bacteria, or even pests, using pesticides, insecticides, and herbicides, or endocrine disruptors […]

(Beyond Pesticides, December 12, 2024) A literature review of 161 articles in Discover Toxicology finds that pesticides with different mechanisms of action cause memory and learning impairments. These effects are noted in nontarget species including humans. Pesticide “[e]xposure during development, as well as chronic environmental and occupational exposure, can contribute to decreased cognitive performance,” the researchers say. With a focus on organophosphate pesticides, synthetic pyrethroids, and neonicotinoid insecticides, the authors highlight neurological impacts. Both learning and memory are crucial for the survival of many species. “Considering the importance of learning and memory for human and non-human animal behavior and the growing association between pesticide exposure and cognitive impairment, the aim of this review was to describe the studies showing the impact of pesticide exposure on memory and learning abilities in nontarget species, providing evidence of the impact of pesticides in central nervous system function,” the researchers state. The 161 articles included in the review were identified through database searches in PubMed/Medline and Scielo. The authors note, “Inclusion criteria for article selection included all articles published in English between 2015 and 2024 containing original studies in animals or humans with single or multiple pesticides exposure.” The articles consist of 132 preclinical […]

(Beyond Pesticides, November 26, 2024) A study in Environment International finds that young children who exhibit higher levels of pesticide metabolites in their urine show more pronounced neurobehavioral problems at the age of ten. Researchers in China document how exposure during early childhood, especially during the sensitive window before the age of two, is linked to hyperactivity/inattention problems such as attention deficit hyperactivity disorder (ADHD). While adding to the body of science connecting pesticide exposure to learning and developmental disorders, this study offers a “novel perspective on characterizing the fluctuation in repeated measurements of multiple environmental chemicals and identifying the potential critical windows,” the authors share. (See previous Daily News coverage here, here, and here.) The researchers analyze data from questionnaires and urine samples through the ongoing Sheyang Mini Birth Cohort Study (SMBCS), which is a long-term prospective cohort study that associates environmental chemical exposure during pregnancy and childhood to negative health effects. This data addresses combined pesticide exposures in young children with neurobehavior analyses at the age of ten to determine any correlation. Within the SMBCS, a total of 1303 pregnant women are enrolled. When the children reached ages one, two, three, six, seven, eight, nine, and ten years […]

(Beyond Pesticides, October 8, 2024) A comprehensive literature review in Endocrines, published in September, amasses hundreds of studies on endocrine-disrupting chemicals (EDCs) that showcase adverse effects on growth, development, reproduction, and metabolism. The authors, a team of scientists and academics from Brazil, shed light on the link between EDC use and thyroid dysfunction, leading to increasingly prevalent illnesses and deadly diseases.     EDCs are any synthetic or natural compounds that hinder endocrine system functions and create harmful effects on organisms. These chemicals can impact the thyroid gland, which is vital in producing hormones and plays a role in several body functions. As the researchers state, “Several EDCs have been classified as thyroid disruptors, impairing thyroid hormone [TH] production, synthesis, metabolism, transport, and/or actions. Notably, thyroid disorders are the second most prevalent endocrine disease worldwide, with incidence increasing significantly in recent years.” The authors continue, “[S]tudies have correlated this rise in thyroid dysfunctions and cancers with increased exposure to EDCs. Although many EDCs are linked to thyroid dysfunction, this review focuses on the deleterious effects of plasticizers, organochlorine pesticides, and per- and poly-fluoroalkyl substances on thyroid function. These contaminants are commonly found in food, water, and everyday products.” This review helps […]

(Beyond Pesticides, October 2, 2024) A comprehensive literature review in Ecotoxicology and Environmental Safety links a heightened risk of spontaneous abortion (SAB) with pesticide exposure. “The strengths of our study include being the first systematic review and meta-analysis to explore the association between exposure to pesticides and the risk of SAB,” the authors say. This novel approach includes analyzing 18 studies, totaling 439,097 pregnant participants, that allows the researchers to highlight an important public health issue and raise concerns for maternal contact with the harmful chemicals in pesticide products. SAB, also known as spontaneous miscarriage, is defined as the loss of pregnancy occurring prior to 20 weeks of gestation. “It has been observed that approximately 10–15% of pregnancies end up terminating spontaneously,” the researchers report. According to the authors, these negative birth outcomes can be attributed to many factors such as advanced maternal age, anatomical, immunological, and endocrinological disorders, infections, tobacco use, alcohol intake, abnormalities of the placenta, and exposure to heavy metals, radiation, and pesticides. To connect SAB specifically to pesticide exposure in mothers, a literature search was conducted for peer-reviewed studies that include pregnant study participants, ages 16 and above, who report “exposure to one or more pesticides […]

(Beyond Pesticides, September 19, 2024) An article published in the journal Science of the Total Environment finds that the European Union’s (EU) risk assessment process, required for registration, fails to accurately or reliably predict pesticide exposure rates, sometimes by several orders of magnitude. Pesticide registration in the EU leverages the Agricultural Operator Exposure Model (AOEM)—a predictive model developed in 2014 to estimate expected non-dietary pesticide exposure levels for operators [pest control operators in the U.S.] based on a very limited set of data generated by the pesticide industry. Models that predict real-world exposure and underestimate field data raise critical questions about the efficacy of risk assessment reviews that determine product labels and allowed level of harm. By comparing the dermal exposure measured during a field study conducted in a nonagricultural area with the corresponding values estimated by AOEM, researchers in France add to the body of scientific literature indicating that the fossil fuel and petrochemical pesticide industry data cannot be relied upon as a benchmark to ensure public health and safety. The study describes the difficulty and complexity of calculating the ability of protective equipment to provide protection. According to the authors, “[AOEM] underestimated hand exposure by 42 times and […]

(Beyond Pesticides, September 16, 2024) After the release of a hard-hitting study last week published in Science that pinpoints the cycle of increasing pesticide use with ecosystem and bat decline, resulting in higher infant mortality, Beyond Pesticides is calling for state and local action to transition public land to organic practices. Without a healthy ecosystem, the study documents increased pesticide use with dramatic adverse health effects. To take corrective action, Beyond Pesticides’ action asks governors and mayors to do the following: Eliminate the use of pesticides that imperil bats by adopting biodiversity conservation goals including— (1) ecological mosquito management with measures that recognize the benefit of preventive strategies, establish source reduction programs to manage breeding sites on public lands, educate on the management of private lands, employ programs for larval management with biological controls, and eliminate the use of toxic pesticides; (2) prohibition of systemic insecticides and treated seeds, including neonicotinoids; and (3) land management on public lands—including hospitals, higher education institutions, schools, and parks—using regenerative organic principles and organic certified practices and products, to transition to a viable organic system that prioritizes long-term health of the public, ecology, and economy. The new research connects declines in bat populations with increased […]

Image: Art Page submission from Sara Grantham, “Sunflower Pollinators”  (Beyond Pesticides, August 23, 2024) A study in Science of The Total Environment calculates and compares pesticide risk in 594 wild bee species associated with crops in North America. Current pesticide risk assessments that analyze effects on bees primarily focus on a limited subset of species and do not provide comprehensive protection of all wild bees. “Species commonly proposed as models for pesticide risk assessments may not accurately represent risk for those bee species facing the highest potential risk in agricultural contexts,” the authors postulate. The researchers continue, “This study presents a novel approach to characterize and compare the relative potential pesticide risk among wild bee species of their association with crops in North America using suites of intrinsic bee traits to quantify species’ vulnerability and extrinsic factors based on the toxic load of crops for bees and the strength of each species’ association with those crops.” In considering multiple factors that vary by species and determining potential harm to each from pesticide exposure, this study highlights the inadequacies of the current risk assessment process used by the U.S. Environmental Protection Agency (EPA).    The system for risk assessment for pesticides that […]

(Beyond Pesticides, August 22, 2024) A screening and analysis of 36 pesticides finds traces of these chemicals in patients with “unexplained chronic kidney disease” from agricultural communities in the Indian province of Uttar Pradesh. Researchers conducting this study, published in the Journal of Toxicology and Environmental Health Sciences, identify organophosphates, organochlorines, and pyrethroids as the main culprits, building on years of existing research pointing to adverse health impacts originating from bioaccumulation of pesticides after acute and chronic exposure. Chronic kidney disease (CKD) is a condition that afflicts one in ten adults internationally, based on a peer-reviewed analysis from The Lancet. The Centers for Disease Control and Prevention (CDC) estimate that one in seven U.S. adults (or roughly 35.5 million people) have CKD, with as many as nine in ten adults with the disease undiagnosed, based on 2023 data. The correlation between high rates of CKD and multigenerational use of and reliance on pesticides for food production, lawn care, and general land management reinforces the calls of advocates, farmers, and health professionals to adopt a new approach rooted in organic principles. Methodology This study was conducted by a group of researchers from the Department of Chemistry at Babu Banarasi Das University […]

(Beyond Pesticides, August 21, 2024) A literature review, published this month in the Journal of Agricultural and Food Chemistry, explores levels of pesticide residues found in samples of human urine with environmental exposure and dietary intake and confirms prior findings about the benefits of an organic diet. Similar to past findings, lower concentrations of chemicals are detected in the urine of participants who report eating an organic diet. By analyzing 72 scientific research studies published between 2001 to 2023, the review assesses routes of exposure and “explores urinary concentrations and detection frequency of metabolites of organophosphates and pyrethroids, as well as herbicides such as 2,4-D and glyphosate,” the authors say. While “exposure to pesticide residues is influenced by a variety of demographic factors, including occupation, agricultural practices, seasonal variations, residence, diet, age, and gender,” the authors say, the concentrations of pesticides and their metabolites in human urine highlights the disproportionate risk to certain groups as well as the overall threat to the health of humans and the environment. Pesticide exposure can occur from dermal/skin contact or inhalation, through residence or work, and with dietary intake. “Pesticides in urine can be detected as parent compounds, specific metabolites corresponding to a specific […]

(Beyond Pesticides, August 14, 2024) Pesticide exposure is linked to negative birth outcomes in a recent study in the American Journal of Epidemiology. This study adds to that body of science, but is novel research since, “Epidemiological studies of pesticide exposures and stillbirth in the United States have not been published in the past two decades, a time period that has seen dramatic changes in pesticide use compared to the 20th century,” the authors state. The study analyzes Arizona pesticide use records and birth certificates from 2006-2020. Researchers correlate mothers living within 500 meters of any pyrethroid, organophosphate (OP), or carbamate insecticide applications during specific windows before and during pregnancy with stillbirth. The authors focus on exposure during the prenatal period, as it is a susceptible time frame in which any contact with pesticides can negatively impact health. Numerous studies report several adverse birth and childhood outcomes with prenatal exposure. To link pesticide exposure and negative birth outcomes, Arizona records that encompass 1,237,750 births, 2,290 stillbirths, and 27 pesticides were analyzed. The authors “evaluate associations of pyrethroids, OPs, and carbamate insecticides with stillbirth by using data from the Arizona Pregnant women’s Environment and Reproductive outcomes Study (Az-PEARS), a project that […]

(Beyond Pesticides, July 16, 2024) Yet another study in the August 2024 journal Ecotoxicology and Environmental Safety has found that exposure to organophosphorus pesticides (OPPs) is correlated with increased suicidal thoughts in some people. This study is just the latest in a long line of studies from around the world that have linked pesticide exposure to mental health conditions, including sleep disorders, depression, and suicidal ideation (SI). As the rate of suicide increased by 30% between 2000 and 2020, there is an urgent public health need to investigate and address all potential contributing factors. A 2019 study, covered in Daily News, found that teens and adolescents living in agricultural areas and exposed to organophosphate (OP) insecticides are at higher risk of depression, In July and January this year, other studies link farmer psychiatric episodes to pesticide exposure, adding to the body of science. Exposure to household pesticides is also linked to depression in a 2020 study.   Study and Methodology  The study entitled “Association between exposure to organophosphorus pesticide and suicidal ideation among U.S. adults: A population-based study,” analyzes information on the mental and physical health of over 5,000 individuals aged 20 and up in the United States. The study aims […]

(Beyond Pesticides, July 9, 2024) Last month, California cannabis regulators recalled a pesticide-tainted vape, one of the contaminated products identified in a Los Angeles Times investigation. The report reveals that the California Department of Cannabis Control (DCC) has for months been aware of the presence of dangerous chemicals in legal cannabis sold to the public. Conducted by Los Angeles Times and WeedWeek, a cannabis industry newsletter, the investigation has uncovered alarming levels of the insecticide chlorfenapyr in legal cannabis products sold in state dispensaries. According to an article via the National Institutes of Health, “Although [chlorfenapyr] has been identified as a moderately toxic pesticide by the World Health Organization (WHO), the mortality rate of poisoned patients is extremely high. There is no specific antidote for chlorfenapyr poisoning.” The chemical is associated with adverse liver effects and is toxic to bees, birds, and aquatic organisms. Despite claims that the state’s cannabis is safe and regulated, many popular brands of vapes and pre-rolled joints were found to contain dangerous pesticides at levels exceeding state limits and federal standards for tobacco. This investigation comes on the heels of the discovery of large amounts of illegal Chinese pesticides at cannabis grow operations around the state. […]

(Beyond Pesticides, July 8, 2024) Please submit comments by Wednesday, July 31, 2024. Acephate, an insecticide and member of the highly toxic organophosphate (OP) family, is so toxic that EPA is proposing to ban all uses except the systemic injection into trees. A comment period is open, and EPA is accepting comments through Wednesday, July 31, after extending the earlier July deadline. With this remaining use, EPA is still not recognizing that systemic neonicotinoid pesticides can cause serious environmental harm to the ecosystem through indiscriminate poisoning of organisms. >> Submit a comment on acephate and tell EPA that no pesticide should be allowed to be used if the crop can be produced organically.  EPA proposes to cancel all uses of acephate other than tree injection to eliminate all risks of concern it has identified that exceed its level of concern for dietary/drinking water risk, residential and occupational risks, and risks to non-target organisms. As Beyond Pesticides points out, although the tree injection method does not pose excessive dietary or aggregate health risk and does not pose any untoward occupational or post-application human health risks of concern, there are significant ecological risks posed that the agency has neglected. Rather than assessing the ecological risks of tree […]

(Beyond Pesticides, July 5, 2024) After years of advocacy against corporate interference in global pesticide policy, the United Nations Food & Agriculture Organization (FAO) has ended its “strategic partnership” with petrochemical pesticide and fertilizer trade association CropLife International. This decision, which allows the expiration of a 2020 Letter of Intent (LoI), was announced in a June press release by a coalition of international public interest, environmental, and trade groups. The organizations objected to the partnership from the inception of the agreement and has issued objections, including in 2022 and covered by Daily News. The signatories to the release last month believe that this severing of ties with the chemical industry will contribute to building momentum from frontline communities for “sustainable, resilient and equitable production systems under the agroecological paradigm.” The groups say, however, “We remain concerned about the FAO’s continuing informal engagements with CropLife and call for greater transparency and accountability in this regard.” Beyond Pesticides has urged that models for change, whether advanced by FAO or other international or national institutions, must embrace clear definitions and standards that are certified and enforceable in order to reverse the existential threats to health, biodiversity, and climate from petrochemical pesticides and fertilizers. […]