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Findings Show Endocrine-Disrupting Glyphosate Weed Killer Threatens Women’s Reproductive Health

Thursday, April 17th, 2025

(Beyond Pesticides, April 17, 2025) A literature review in Reproductive Sciences finds glyphosate (GLY) and glyphosate-based herbicides (GBH) impact women’s reproductive health, adding to the long list of documented harm from this widely used weed killer. The authors note, “Considering the widespread use of GLY, the controversy regarding its endocrine-disrupting potential and reproductive toxicity, and the innumerable lawsuits filed against Bayer and Monsanto by consumers for morbidities related to Roundup™ exposure, the purpose of this review is to summarize the current literature on the potential adverse effects of GLY and GBHs on the female reproductive tract and discuss possible clinical implications on reproductive health outcomes, including polycystic ovarian syndrome (PCOS), endometriosis, and female fertility.”  Glyphosate and aminomethylphosphonic acid (AMPA), the primary metabolite (breakdown product) of GLY, are found throughout the environment in soil and water, as well as in samples of blood, urine, seminal plasma, and breast milk. Studies have detected residues in farmworkers, as well as “in the urine of 60–80% of the general public in the USA, including pregnant women and children.” (See studies here, here, and here.) The ubiquitous use of GLY and GBH, and subsequent persistence, threatens the health and well-being of all.  Previous studies have […]

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Literature Review of Over 200 Studies Highlights Pesticide Threats to Women’s Reproductive Health

Tuesday, April 8th, 2025

(Beyond Pesticides, April 8, 2025) A comprehensive literature review in Environment & Health analyzes evidence from human biomonitoring, epidemiological studies, and toxicological studies that link adverse effects on women’s reproductive health, specifically impacting the ovary, to pesticide exposure. In examining the scientific literature, consisting of over 200 studies performed in the last 25 years, the authors find pesticide exposure threatens women’s health through ovarian dysfunction. “Epidemiological studies have shown that pesticide exposures are associated with early/delayed menarche [first occurrence of menstruation], menstrual cycle disorders, early menopause, long time to pregnancy, polycystic ovary syndrome, primary ovarian insufficiency, infertility, and implantation failure in women,” the researchers state. They continue, “Both in vivo [in animals] and in vitro [in cells] studies have shown that exposure to pesticides disrupts the estrous cycle, reduces the follicle pool, alters hormone levels, and impairs oocyte [egg] maturation.” These reproductive implications are noted with many different classes of pesticides, such as insecticides, including organochlorine pesticides (OCPs), organophosphates (OPs), pyrethroids, and neonicotinoids, as well as herbicides and fungicides. The authors, however, comment on present research gaps: “Much of the available epidemiological evidence focuses on legacy insecticides, such as OCPs, and a subset of insecticides that are still in use […]

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Landmark Agricultural Pesticide Use Notification Takes Form, as Efforts to Eliminate Pesticides Gain Traction

Friday, April 4th, 2025

(Beyond Pesticides, April 4, 2025) In March, the California Department of Pesticide Regulation (DPR) announced the launch of SprayDays California, “a first-of-its-kind statewide system designed to provide transparent, accessible and timely notifications and information about the use of specific pesticides[,]“ according to the agency’s press release. The state says that notification will occur in “advance of the scheduled use of California restricted material pesticides in production agriculture.” Growing out of the passage of AB 617 Community Emissions Reduction Act in California, passed in 2017, farmworker safety advocates have long been urging an implementation strategy that provides notification of pesticide spraying. In late 2017, the California Air Resources Board (CARB) began implementation of AB 617, a bill enacted with the stated intent of addressing the air quality crisis in many communities of predominantly people of color who are disproportionately harmed by toxic chemicals. While the overall goal of the law is to reduce air pollution in these communities, farmworker advocates have sought to operationalize a pesticide spraying notification system to warn communities when nearby spraying is scheduled to take place. The idea behind notification programs and transparency in government is that it enables those potentially exposed to take precautionary measures to […]

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Research Spotlights New Hazard Severity of Chlorpyrifos, Ag Insecticide Widely Found in Food Supply

Thursday, April 3rd, 2025

(Beyond Pesticides, April 3, 2025) As highlighted by Beyond Pesticides in recent comments to the U.S. Environmental Protection Agency (EPA), chlorpyrifos (CPF) has been under scrutiny for decades due to associated adverse health effects, noted particularly in the extensive and consistent scientific evidence of neurotoxic dangers to children’s health. The latest research on CPF, published in Environmental Toxicology and Genes & Diseases, reveals additional threats to the immune system and male reproduction that are not captured in current EPA risk assessments of chlorpyrifos and raises serious health questions, given that residues are found throughout the food supply. CPF, a widely used organophosphate insecticide in agriculture, is a cholinesterase inhibitor that binds irreversibly to the active site of an essential enzyme for normal nerve impulse transmission, acetylcholine esterase (AChE), inactivating the enzyme. Many insecticides, including organophosphates and carbamates, target AChE, causing them to be highly toxic to both insects and mammals that have this enzyme as a crucial part of their nervous systems. The history of chlorpyrifos exemplifies the failure of pesticide law and policy, as this chemical, among many others, not only has direct adverse health effects but is contributing to the climate crisis, biodiversity collapse, and disproportionate levels of […]

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Study Finds Reproductive System Effects in Adolescents with Prenatal Pesticide Exposure

Wednesday, April 2nd, 2025

(Beyond Pesticides, April 2, 2025) In examining prenatal residential proximity of documented pesticide spraying in California to the menstrual cycle characteristics of 273 Latina adolescents, researchers report in the American Journal of Epidemiology a positive association between exposure to the insecticide methomyl and heavy bleeding. Other pesticides appear to influence menstrual symptoms as well. “Adolescents’ menstrual cycle characteristics can be ‘vital signs’ of health and impact quality of life,” the authors share. They continue, “To our knowledge, this is the first study to examine the association between prenatal pesticide exposure and menstrual outcomes in adolescents of any demographic group.” Menstrual cycle characteristics, such as dysmenorrhea (painful or uncomfortable menstrual cramps), irregularity, and heavy menstrual bleeding, can also be indicators of underlying health conditions, including endometriosis, polycystic ovary syndrome (PCOS), thyroid dysfunction, and bleeding disorders. By associating the pesticide exposure of mothers during pregnancy to impacts on their children, the researchers highlight important health risks for women and young girls that are often disregarded. “The prenatal period is a critical period of reproductive development that may be particularly sensitive to endocrine disruption,” the researchers share. As previously reported by Beyond Pesticides, endocrine-disrupting chemicals are any synthetic or natural compounds that hinder […]

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Study Finds Spermiotoxicity and Impacts on Male Mammal Fertility with Ipconazole Fungicide Exposure

Tuesday, March 11th, 2025

(Beyond Pesticides, March 11, 2025) A study in Toxics analyzes ipconazole, a triazole fungicide often used as a coating on treated seeds and as a foliar treatment on the leaves of plants. “Triazole pesticides are widely used throughout the world, but their abuse causes toxic effects in non-targeted organisms,” the researchers state. In the current study, unintended reproductive effects are noted in male sheep (ram) and pigs (also known as porcine or swine). This research focuses on the impact of ipconazole exposure on spermatozoa (sperm) in two mammal species and finds spermiotoxicity through significantly reduced sperm viability, as well as alterations in enzyme and gene expression related to fertility.  “To our knowledge, this is the first study to evaluate the cytotoxic effect of the triazole ipconazole on mammalian spermatozoa,” the authors share. This analysis utilizes semen samples from the Reproductive Biotechnology Laboratory of the Major National University of San Marcos in Lima, Peru, the university where six of the nine researchers are Faculty of Veterinary Medicine.   “The sperm were exposed to ipconazole concentrations of 1, 5, 10, 50 and 100 ÂľM, and to a control without ipconazole,” they say. Similar concentrations have been used in previous cytotoxicity studies with ipconazole. […]

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Catastrophic Harm to Women from Pesticides Drives Call for Their Elimination

Monday, March 10th, 2025

(Beyond Pesticides, March 10, 2025) Following International Women’s Day, celebrated on March 8, 2025, the poignant findings on women, gender, and hazardous substances in a United Nations report raise critical issues of concern and cause for urgent action to phase out petrochemicals. The Report of the Special Rapporteur on the implications for human rights of the environmentally sound management and disposal of hazardous substances and wastes, by Marcos Orellana, was delivered to the 79th Session of the United Nations General Assembly in July 2024. Excerpts from the report follow: “Women make up roughly 60 to 70 per cent of the agricultural labour force in developing countries where pesticides and pesticide handling are especially poorly regulated. In Zambia, for example, two thirds of the labour force is engaged in agriculture, and 78 per cent are women farmers and peasants. Women there play a significant role in pesticide application, often without any or adequate personal protective equipment, especially during activities such as weeding, harvesting, and washing pesticide-laden clothes.” “In higher-income countries, women who do agricultural work are often poor and/or migrants; pesticides are one of many dimensions of marginalization and damage to their well-being. The European agriculture sector uses many seasonal and […]

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On International Women’s Day, Pesticide Risks to Women’s Health Call for Urgent Transition to Organic

Friday, March 7th, 2025

(Beyond Pesticides, March 7, 2025) In honor of International Women’s Day on Saturday, March 8, 2025, Beyond Pesticides sheds light on the disproportionate risks to women from toxic chemicals that are often unaccounted for and even dismissed throughout pesticide regulatory review and the underlying statutes. In a roundup of Daily News coverage in 2024, as well as the most recent scientific studies in 2025, on the scientific links between pesticide exposure and adverse effects in women, this article highlights the growing inequities in pesticide threats to women’s health.  Women farmers and farmworkers are particularly excluded when assessing pesticide risks. As previously reported by Beyond Pesticides, a study published in Occupational and Environmental Medicine finds that pesticide exposure, especially during puberty, can play a role in ovarian cancer development among female farmers. Although there are many studies that evaluate the risk for cancers among farmers, very few scientific articles cover the risk of ovarian cancer from pesticide exposure.  Additionally, this study suggests the role of hormones in ovarian cancer prognosis and development, highlighting an association with endocrine disruption. Endocrine disruption can lead to numerous health problems in multiple organ systems, including hormone-related cancer development (e.g., thyroid, breast, ovarian, prostate, testicular), reproductive […]

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Children Exposed to Pesticides Experience “Cellular Distress” and Chronic/Acute Diseases, Study Finds

Friday, February 28th, 2025

(Beyond Pesticides, February 28, 2025) It is well established that children are more vulnerable than adults to environmental insults such as pesticides, from conception onward. Children living in agricultural areas are exposed differently from those in urban areas. A study of rural children by researchers at Mexico’s Universidad AtĂłnoma de Nayarit compared two communities located less than a quarter of a mile from agricultural fields with one control community located more than a mile away. The study shows that children in the field-adjacent towns are clearly exposed to pesticides and are experiencing cellular distress as a result. The state of Nayarit is on the west coast of Mexico near Mazatlan. Rural children encounter aerial application, spray drift, and erosion. If their parents are agricultural workers and especially if they apply pesticides, they bring home residues on their clothes. Residential storage of pesticides and small children’s propensity to play in the dirt and put things in their mouths exacerbate their exposure. Urban children get hit by pesticides in their homes, schools, and parks. The researchers took blood and urine samples from 431 children aged six to 12 and collected questionnaires as to pesticide exposures from the parents or guardians. They assayed the […]

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Exposure to Glyphosate Herbicide Adversely Affects Perinatal Health, Study Finds

Thursday, February 20th, 2025

(Beyond Pesticides, February 20, 2025) Researchers at the University of Oregon found that the rollout of genetically engineered corn in the early 2000s, followed by exponential increases in glyphosate-based herbicides, “caused previously undocumented and unequal health costs for rural U.S. communities over the last 20 years.” Their results “suggest the introduction of GM [genetically modified] seeds and glyphosate significantly reduced average birthweight and gestational length.” The conclusions of this study emerge as fossil fuel advocates, including President Donald Trump, are mobilizing to pioneer “energy dominance” despite the market movement toward renewable energy. Just as chemical-intensive farmers and land managers continue to spray synthetic fertilizers and pesticides, a successful rollout of alternatives must rely on feeding the soil rather than the plant. Advocates continue to demand that elected officials and regulators embody the precautionary principle and scientific integrity in decision-making. Given the hostile federal climate on anything relating to holistic solutions, communities are coming together to move beyond input-dependent land management systems and adopt organic criteria of allowed and prohibited substances, mandatory public comment process, independent third-party certification, and a federal advisory board (National Organic Standards Board) consisting of farmers, environmentalists, consumers, scientists, economists, researchers, and other stakeholders, with binding recommendations […]

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Love Your Heart This Valentine’s Day by Following the Science on Pesticides

Friday, February 14th, 2025

(Beyond Pesticides, February 14, 2025) A study in the European Journal of Preventive Cardiology finds that organic food consumption lowers the risk of developing atherosclerotic cardiovascular disease (ASCVD). Heart health is important not just on Valentine’s Day, but every day. While celebrating with friends and family, consider spreading love in ways that promote long-term health and wellness with an organic meal paired with organic flowers and chocolates. Eliminating exposure to petrochemical pesticides and synthetic fertilizers, such as with an organic diet, mitigates disease risks including brain and nervous system disorders, cancer, endocrine disruption, and cardiovascular disease (CVD). In this latest study, the scientists and doctors analyze registered diagnoses of ASCVD from the Danish National Patient Register in comparison with the diets of a cohort of middle-aged women and men from the Danish Diet, Cancer and Health study. The eligible study participants, including 41,407 men and women of which 5,365 developed ASCVD, filled in a detailed 192-item food frequency questionnaire and a lifestyle questionnaire on their consumption of organic vegetables, fruit, dairy products, eggs, meat, and bread and cereal products. The authors report that the results show overall organic food consumption is associated with a 6% lower incidence rate of ASCVD. […]

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Pesticides that Adversely Affect Cell Function Linked to Brain Cancer

Friday, February 7th, 2025

(Beyond Pesticides, February 7, 2025) With the strong associations established in epidemiologic studies and a dearth of evidence on the actual mechanisms by which pesticides inflict their damage on the brain, a new meta-analysis identifies studies that pesticides can overwhelm cells’ defenses against them, interfere with cell communication in the brain, and disrupt the epigenetic (gene function) regulation of gene expression. In the journal Nucleus, Bilal Ahmad Mir, PhD and colleagues at the University of Kashmir in Srinagar, India, review what is known at the molecular level about pesticides’ role in brain cancer. Brain cancer is a heavy burden for its victims and their families, and attributing a cause is, as with many diseases, fraught with difficulty. But there are strong clues: For example, farming is a known risk factor. In a 2021 meta-analysis of epidemiologic studies between 1998 and 2019, analyzed here by Beyond Pesticides, farming was associated with a 13% increase in the risk of brain cancer. For farmers whose specific exposure to pesticides was documented in the studies, the increase jumped to 20 percent. So there is some reason to point a finger at synthetic chemicals. But agricultural workers are not the only ones at risk. According […]

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Revealing “Dirty Weed”: Pesticides in Cannabis Raises Health Concerns, as Advocates Advance Organic Solution

Thursday, February 6th, 2025

(Beyond Pesticides, February 6, 2025) Months after publishing a June 2024 study regarding concentrations of pesticides discovered in legal (and illegal) cannabis products in California, the Los Angeles Times has released a follow-up exposĂŠ highlighting extensive pesticide contamination, including from “hidden” pesticides that regulators have not monitored. The authors conclude that in California’s legal weed market, over half of available smoking products are found to contain hidden chemicals—toxic pesticides present in products but not regulated or monitored by state authorities. Since 2015, Beyond Pesticides has laid out health, safety, and environmental concerns related to the contamination of cannabis by pesticides (and fertilizers) alongside an imperative need to mandate an organic systems approach to cannabis production. Yet ten years later, it appears nationally that California state regulators are alone in moving forward in 2021 with state organic cannabis certification. There are other marketplace-based cannabis certification labels that require comparable organic certification practices (see Beyond Pesticides reporting here and here). For more information, please see past Pesticides and You reporting here and here. The Los Angeles Times analyzed the results from state licensed laboratory testing of more than 370 legal cannabis products, representing 86 brands. In addition to the 66 chemicals required […]

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Study Demonstrates Health Benefits of Organic Diet Over That Consumed with Toxic Pesticides

Tuesday, February 4th, 2025

(Beyond Pesticides, February 4, 2025) Adopting a fully organic diet can reduce pesticide levels in urine within just two weeks “by an average of 98.6%” and facilitate faster DNA damage repair relative to a diet of food grown with chemical-intensive practices, according to findings from a randomized clinical trial published in Nutrire. The authors explain that their finding “is likely due to two main factors: the presence of compounds characteristic of [an organic] diet, which may have high levels of antioxidants that can protect DNA and also induce DNA repair [], and the absence or decrease in the incidence of pesticides in this type of diet, which are recognized for their genotoxic effects and have the ability to affect the genetic repair system of organisms [].” Public health professionals and affected families continue to sound the alarm on the unprecedented rates of chronic illnesses, many linked to pesticide exposure, as well as the urgency in developing solutions that acknowledge the connection to policies governing agriculture, nutrition policies, and public health. Background and Methodology The purpose of this study is to identify any relationships in health effects of chemical-intensive versus organic diets in a two week-period. More specifically, the authors say […]

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Sleep Disorders in Farmers and Farmworkers Linked to Pesticide Exposure in Study Supporting Similar Findings

Friday, January 31st, 2025

(Beyond Pesticides, January 31, 2025) A recent cross-sectional study in Heliyon highlights the link between sleep disorders in Thai farmers and pesticide exposure. The authors find pesticide exposure as an important risk factor for sleep disorders after surveying 27,334 farmers over the age of 20 who had work experience for at least five years. The importance of sleep health is reflected both physically and mentally, as studies find “sleep deficiency increase[s] mortality and various health complications, including hypertension, obesity and type 2 diabetes, cardiovascular diseases, mood disorders, and neurodegenerative disorder.” Additional studies find that these issues are compounded when sleep health is affected by environmental factors such as pesticide exposure. (See previous Beyond Pesticides’ coverage here and here.) The researchers report: “The study found a positive association of 19 individual pesticides (twelve insecticides, two herbicides, and five fungicides). Some associations demonstrated a dose-response pattern. Additionally, the study revealed that women are at a higher risk of sleep-related issues with pesticide exposure compared to males. These results not only substantiate existing literature but also unveil several new individual pesticides that may impact sleep health.” Focusing on study participants in Thailand, which is “characterized by heavy pesticide use and minimal protective measures, […]

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Lit Review Shows Depth of Research Linking Pesticide-Induced Effects on Immune System, Leading to Disease Outcomes

Wednesday, January 15th, 2025

(Beyond Pesticides, January 15, 2025) There is robust scientific literature that unpacks the adverse human health effects of pesticide exposure, however immunological impacts do not receive adequate attention in regulatory review processes, according to an in-depth literature review. In a piece published in Frontiers in Immunology (2024) critiquing recent peer-reviewed scientific studies, as well as unpublished research produced by the Institute of Biology and Experimental Medicine in partnership with the National Scientific and Technical Research Council in Argentina, researchers assess immune system effects of pesticide exposure, which creates the conditions for deadly health conditions including various forms of cancer. The focus of this study, according to the authors, is “to critically review fundamental aspects of toxicological studies conducted on PPPs [Plant Protection Products] to provide a clearer understanding of the risks associated with exposure to these compounds on human health.” PPPs are pesticide products that contain more than one active ingredient, and can include synergistic ingredients that supercharge them alongside inert ingredients that pesticide companies are not legally required to disclose under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), but are often manipulated biologically and chemically active. Most studies analyze the toxicological impacts of active ingredients in isolation rather […]

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Initiative in the European Union Embraces Organic as a Climate Solution, as Fires Accelerate in the U.S.

Friday, January 10th, 2025

(Beyond Pesticides, January 10, 2025) [Beyond Pesticides grieves for those tragically harmed by the Los Angeles fires.] As the new year begins with the bleak and devastating reminder brought on by the Los Angeles fires, the nation and world are reminded once again that dramatic land management changes are necessary to address the erratic weather conditions contributing to the force and effect of the fires and the length of the fire season. This is only the most recent reminder, as Beyond Pesticides and many organizations call for an urgent end to land management practices and inputs that rely on the production and use of petrochemical pesticides and fertilizers, which contribute to the global climate crisis. Often incorrectly referred to as natural disasters, environmental disasters, including fires, floods, and severe weather events, are brought on or exacerbated by widespread reliance on disruptive chemicals, which played a role in a delayed start to the southern California rainy season, hurricane-force winds, and low humidity levels—all elevated by climate change. As organic is increasingly understood to be a climate solution, OrganicClimateNet last year launched an aggressive effort to build the base of organic farmers in the European Union (EU).   As the climate crisis […]

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Deadly Poisoning of Dozens of Children in South Africa Highlights Global Pesticide Threat to Human Life  

Thursday, December 19th, 2024

(Beyond Pesticides, December 19, 2024) As The New York Times reported last month, the government in South Africa declared a national emergency—23 children died and nearly 900 people were sickened from pesticide poisoning in Johannesburg’s Soweto township. The illnesses and fatalities have been traced to small amounts of highly neurotoxic pesticides, including the insecticides terbufos and aldicarb, found in local food items. These chemicals, described by South African President Cyril Ramaphosa as “street pesticides,” are being increasingly used (legally and illegally) for pest infestations in the townships and informal settlements of South Africa’s poorest communities, where poverty and inadequate waste collection exacerbates the pest management challenges. Without formal electricity, running water, or municipal garbage collection, many residents rely on highly toxic pesticides for pest infestations in their homes and makeshift markets, resulting in food inadvertently being contaminated with pesticides.  The announcement highlights the dangers of allowing these highly toxic agricultural chemicals to be used in farming, with tragic consequences for vulnerable communities when they are diverted for use in urban settings. This tragic situation also draws attention to the elevated threat that pesticides pose when stringent enforcement mechanisms are not in place to ensure compliance with pesticide restrictions, even with […]

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Study Links Numerous Chemical Families of Pesticides to Endocrine Disrupting Effects, Including Obesity

Tuesday, December 17th, 2024

(Beyond Pesticides, December 17, 2024) A systematic review of studies on pesticides as endocrine-disrupting chemicals (EDCs) on body weight, published in Biomedicines, evaluates 36 clinical and preclinical studies and links their agricultural use to obesity. The authors, with the lead researchers from the School of Medicine and Health Sciences at Catholic University of Valencia San Vincente, Valencia, Spain, assess studies on a range of pesticides, including organophosphates, pyrethroids, neonicotinoids, and others. In addition to concluding that the EDCs promote obesity, they report that the chemicals cause “other anthropometric changes by altering lipid and glucose metabolism, modifying genes, or altering hormone levels such as leptin.” Endocrine disruption and obesity are public health concerns, and there is a wide body of science linking pesticide exposure to these effects (see more here). “Obesity is considered to be a worldwide pandemic that leads to an increase in medical costs and thus becomes a public health problem,” the researchers share. They continue, “[Obesity] is also associated with the increased production of environmental chemicals, also called environmental obesogens, used mainly in agriculture, as disease vector control, helping to prevent harmful effects caused by fungi, bacteria, or even pests, using pesticides, insecticides, and herbicides, or endocrine disruptors […]

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EPA’s Registration of Herbicide under New Framework Puts Endangered Species at Elevated Risk, Advocates Say

Friday, December 13th, 2024

(Beyond Pesticides, December 13, 2024) In October, the U.S. Environmental Protection Agency (EPA) approved the registration applications of BASF Corporation and Mitsui Chemicals Crop & Life Solutions, Inc. for the use of different formulations of the L-isomer of glufosinate (also known as “L-glufosinate” and “glufosinate-P”) as new active herbicidal ingredients. This decision marks one of the first times that EPA has employed its new Herbicide  Strategy Framework to determine the level of mitigation necessary to protect listed species and critical habitat under the Endangered Species Act (ESA). Glufosinate is an organophosphate, with known neurotoxic, reproductive/developmental effects, toxic to aquatic life, and mobile in soils (see Beyond Pesticides Gateway). Scientists have found that formulated glufosinate is generally more toxic to aquatic and terrestrial animals than the technical grade active ingredient. Manufacturers are introducing newer glufosinate products as alternatives for glyphosate-based herbicides, like Bayer/Monsanto’s ‘Roundup’ and dicamba. The Center for Biological Diversity notes in comments submitted to EPA on this decision, “L-glufosinate has the potential to be used on tens of millions acres of land every year given the crops EPA has proposed to register it on. The scale of potential use is far above most new active ingredients.” This first significant application […]

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Review Cites Memory and Learning Impairments; Children, Workers, and Nontarget Organisms at Risk

Thursday, December 12th, 2024

(Beyond Pesticides, December 12, 2024) A literature review of 161 articles in Discover Toxicology finds that pesticides with different mechanisms of action cause memory and learning impairments. These effects are noted in nontarget species including humans. Pesticide “[e]xposure during development, as well as chronic environmental and occupational exposure, can contribute to decreased cognitive performance,” the researchers say. With a focus on organophosphate pesticides, synthetic pyrethroids, and neonicotinoid insecticides, the authors highlight neurological impacts. Both learning and memory are crucial for the survival of many species. “Considering the importance of learning and memory for human and non-human animal behavior and the growing association between pesticide exposure and cognitive impairment, the aim of this review was to describe the studies showing the impact of pesticide exposure on memory and learning abilities in nontarget species, providing evidence of the impact of pesticides in central nervous system function,” the researchers state. The 161 articles included in the review were identified through database searches in PubMed/Medline and Scielo. The authors note, “Inclusion criteria for article selection included all articles published in English between 2015 and 2024 containing original studies in animals or humans with single or multiple pesticides exposure.” The articles consist of 132 preclinical […]

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Reflection: Highly Neurotoxic Insecticide Chlorpyrifos To Continue on Major Crops, EPA Defers to Industry

Friday, December 6th, 2024

(Beyond Pesticides, December 6, 2024) On December 2, the U.S. Environmental Protection Agency (EPA) announced yet another milestone in the convoluted life span of the insecticide chlorpyrifos. Under the deceptive headline “EPA Proposes Rule to Revoke Most Food Uses of the Insecticide Chlorpyrifos,” EPA stated that it is improving environmental protection by revoking all usages of chlorpyrifos except for 11 food and feed crops. The proposal was deemed “unconscionable” by Beyond Pesticides executive director Jay Feldman in an article in The New Lede. EPA claims this plan would reduce annual chlorpyrifos application by 70% compared to “historical usage.” Chlorpyrifos is a known neurological and reproductive toxicant. EPA has been cutting back on approved uses for years but is far behind other environmental authorities—the European Food Safety Authority and Thailand have banned it altogether, and California has banned its agricultural use. The trouble with EPA’s latest attempt is that it does nothing to clarify and rationalize EPA’s process, and it will not protect the public, because those 11 remaining products are among the most extensively grown and used in the world: soybeans, sugar beets, cotton, wheat, apples, citrus fruits, strawberries, alfalfa, cherries, peaches, and asparagus. Chlorpyrifos is an organophosphate chemical. These […]

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Pesticide Exposure in Early Childhood Linked to Neurobehavioral Disorders, Study Finds

Tuesday, November 26th, 2024

(Beyond Pesticides, November 26, 2024) A study in Environment International finds that young children who exhibit higher levels of pesticide metabolites in their urine show more pronounced neurobehavioral problems at the age of ten. Researchers in China document how exposure during early childhood, especially during the sensitive window before the age of two, is linked to hyperactivity/inattention problems such as attention deficit hyperactivity disorder (ADHD). While adding to the body of science connecting pesticide exposure to learning and developmental disorders, this study offers a “novel perspective on characterizing the fluctuation in repeated measurements of multiple environmental chemicals and identifying the potential critical windows,” the authors share. (See previous Daily News coverage here, here, and here.) The researchers analyze data from questionnaires and urine samples through the ongoing Sheyang Mini Birth Cohort Study (SMBCS), which is a long-term prospective cohort study that associates environmental chemical exposure during pregnancy and childhood to negative health effects. This data addresses combined pesticide exposures in young children with neurobehavior analyses at the age of ten to determine any correlation. Within the SMBCS, a total of 1303 pregnant women are enrolled. When the children reached ages one, two, three, six, seven, eight, nine, and ten years […]

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