(Beyond Pesticides, January 14, 2025) Women with occupational pesticide exposure have elevated rates of breast cancer, according to a study in Immunopharmacology and Immunotoxicology. Based on an analysis of clinicopathological data from 188 affected women, the study authors demonstrate “that occupational exposure to pesticides modifies the clinical presentation of disease in breast cancer patients, depending on their age at disease onset, affecting cytokine production, especially in those exhibiting early age at diagnosis.”   “Breast cancer (BC) is the most common malignant neoplasm affecting women worldwide and the second leading cause of cancer-related death in this population,” the researchers report. They continue: “Aging is the primary risk factor associated with breast cancer development and mortality, resulting in a cumulative lifetime risk of 1 in 8 women developing the disease. Disease onset significantly impacts patient prognosis. While most cases are of late onset and occur in women over 50 years of age, early-onset BC is prevalent in certain populations and is associated with a poor prognosis and aggressive tumor behavior.”  Data was collected and analyzed from May 2015 to December 2022, with the study population in Brazil spanning “27 municipalities in the southwest of Paraná, a region characterized by extensive pesticide use, predominantly […]

(Beyond Pesticides, January 2, 2025) Adding to the body of scientific literature on the fast escalating antibiotic resistance crisis is a study published by Chinese scientists in Environmental Science & Technology, which shows that antibiotic resistance genes (ARGs) in soils move up through trophic levels via predation. Gut microbiomes of soil fauna have been found to be reservoirs of ARGs. How this process operates in soils is vital, because what happens in soil microbes does not stay there. If bacteria altered in soils move up trophic levels, ARGs may strengthen the multicellular agricultural pests the industry is trying to kill—insects, fungi, plants—not to mention bringing their libraries of resistant genes into the microbiomes of vertebrates, including humans. Antibiotic resistance is a natural phenomenon, but human activity has greatly increased its presence in ecosystems the world over, including in one of the ecological niches of greatest concern to the future of food and human health: soils. Soils are complexes of mineral and organic substrates populated by billions of microorganisms and tiny animals. They are rapidly being degraded by conventional agriculture, forestry, and land management practices generally—more than a third of the world’s agricultural land has already been severely damaged by pesticides, […]

(Beyond Pesticides, December 17, 2024) A systematic review of studies on pesticides as endocrine-disrupting chemicals (EDCs) on body weight, published in Biomedicines, evaluates 36 clinical and preclinical studies and links their agricultural use to obesity. The authors, with the lead researchers from the School of Medicine and Health Sciences at Catholic University of Valencia San Vincente, Valencia, Spain, assess studies on a range of pesticides, including organophosphates, pyrethroids, neonicotinoids, and others. In addition to concluding that the EDCs promote obesity, they report that the chemicals cause “other anthropometric changes by altering lipid and glucose metabolism, modifying genes, or altering hormone levels such as leptin.” Endocrine disruption and obesity are public health concerns, and there is a wide body of science linking pesticide exposure to these effects (see more here). “Obesity is considered to be a worldwide pandemic that leads to an increase in medical costs and thus becomes a public health problem,” the researchers share. They continue, “[Obesity] is also associated with the increased production of environmental chemicals, also called environmental obesogens, used mainly in agriculture, as disease vector control, helping to prevent harmful effects caused by fungi, bacteria, or even pests, using pesticides, insecticides, and herbicides, or endocrine disruptors […]

(Beyond Pesticides, November 20, 2024) The perpetual use of pesticide coated seeds and tillage changed the composition of various beetle, spider, and other epigeal arthropod communities on New Hampshire farmland, according to a recent study published in Agriculture, Ecosystems, and Environment. Researchers fell short of finding conclusive results about the multi-variable impacts of both practices on biodiversity but raise notable issues on the impact of treated seeds. This research builds on the existing peer-reviewed scientific literature that highlights the threats of toxic pesticides and pesticide-coated seeds. Environmental and public health advocates are in agreement with organic and agroecological farmers who reject chemical-intensive land management practices. “At the root of the cascading crises of public health collapse, biodiversity loss, and the climate crisis is a reliance on petrochemical-based toxic products, rather than public policy and investments that strengthen consumer and institutional trust of nature-based, organic systems,” says Max Sano, organic program associate at Beyond Pesticides. “This is consistent with various interactions I have had with advocates across New England who are demanding action to stymie the impending biodiversity collapse enabled by government inaction.” Background and Methodology This study was coauthored and led by environmental researchers at the Department of Natural Resources […]

(Beyond Pesticides, October 9, 2024) An agrichemical industry-funded study published in International Journal of Agricultural Sustainability dissects the development of national organic standards and opportunities that can be applied in expanding the use of “regenerative” agriculture. Not surprisingly, the study authors offer support for integrated pest management (IPM) and reassurance of a rigorous pesticide registration review process before the chemicals are marketed. The study included a survey of five farmers, who farm a total of 100,000 acres, but do not have extensive experience farming organically. For those practicing regenerative organic practices and organic advocates, the bottom line is that the study concludes that a list of criteria that would be needed for regenerative agriculture criteria (e.g., list of allowed substances) already exists within the standards and requirements of the 1990 Organic Foods Production Act (OFPA) and the National Organic Program. Environmental and public health advocates are concerned about this piece representing an industry position being cloaked in an academic journal serving as an obstacle to the widespread adoption and improvement of organic principles and practices. The study was written by four authors with varying levels of connections to CropLife America (the major agrichemical industry trade group), including academic researchers with […]

(Beyond Pesticides, October 7, 2024) American Academy of Pediatrics (AAP) released a newly revised technical report describing how antibiotic use in animal agriculture contributes to the development of antibiotic resistance in medical use and can adversely affect child health— in the context of this fast-emerging threat to U.S. and global health. This AAP finding comes just as the United Nations (UN) held its second High-Level Meeting on Antimicrobial Resistance (AMR) on September 26 (the first was held in 2016) at which global leaders committed “to a clear set of targets and actions, including reducing the estimated 4.95 million human deaths associated with bacterial antimicrobial resistance (AMR) annually by 10% by 2030.” The release from the UN, “World leaders commit to decisive action on antimicrobial resistance,” states, ”The Food and Agriculture Organization of the United Nations (FAO), the United Nations Environment Programme (UNEP), the World Health Organization (WHO) and the World Organisation for Animal Health (WOAH), known as the Quadripartite, welcome the declaration. The Quadripartite applauds countries for recognising the need for global, regional and national efforts to address AMR through a One Health approach, which recognizes that the health of people, animals, plants and the wider environment, including ecosystems, are closely […]

(Beyond Pesticides, October 3, 2024) The American Academy of Pediatrics published a technical report in September on antimicrobial resistance, which it calls a global public health threat, identifying the health implications of antibiotic use in animal agriculture. The lead authors, both medical doctors from the Department of Pediatrics at Vanderbilt University Medical Center, note the rise in antimicrobial-resistant infections that result in increased morbidity, mortality, and health care costs for not only adults, but infants and children as well. “[A]ll use of antimicrobial agents exerts selective pressure that increases the risk of development of resistance,” the authors state, highlighting the importance of limiting antimicrobial uses. “Antimicrobial resistance is an organism’s ability to survive exposure to an antimicrobial agent that was previously an effective treatment. Resistance traits can be acquired either through new mutations or through transfer of genetic material between organisms,” the authors report. Antimicrobial-resistant pathogens, such as bacteria and viruses, can be transmitted “through the food supply, direct contact with animals, environmental pathways, and contact with infected or colonized humans,” they continue. Use of antimicrobial agents, especially over extended periods of time or with repeated exposure, can cause resistance to not only that agent, but to multiple agents. As […]

(Beyond Pesticides, September 24, 2024) Recent commentary in Frontiers in Toxicology by two researchers, Maricel Maffini, PhD and Laura Vandenberg, PhD, highlights the pitfalls in the current regulatory systems in the United States (U.S.) for chemicals that threaten human health. Despite many advancements in science over the past few decades, and the wealth of studies that tie chemical exposure to negative health effects, risk assessments, and subsequent risk management, remain “static” and “outdated,” according to the authors. “There is increasing concern amongst public health professionals, environmental health scientists, and medical organizations about exposures to synthetic chemicals,” the researchers say. “These organizations’ concerns are based on the overwhelming evidence showing associations between chemical exposures and adverse health outcomes in human populations.” Such concerns have sparked a debate on current regulatory methods for chemicals that are present in highly used products, such as pesticides, plastic containers, and food.    The authors continue, “There are now thousands of studies showing associations between these chemicals and adverse health effects in humans including neurological disorders and learning disabilities, metabolic outcomes, infertility, thyroid dysfunction, and cancers.” Additional health effects can be seen in the Pesticide-Induced Diseases Database. Of the many harmful chemicals, per- and polyfluoroalkyl substances […]

(Beyond Pesticides, September 17, 2024) Today, International Microorganism Day, is a prime moment to focus on the complexity of billions of living beings that establish the foundation of land management and food production. Organic advocates, community members, and farmers identify the protection and enhancement of biological diversity in the soil as a key goal, especially in light of mounting concerns over rising microbial resistance to chemical-intensive practices. A recent article in British Journal of Environmental Sciences points to several microbial populations adversely affected by pesticide-contaminated soil on various farmland plots in Nigeria. There are significant variations in bacteria presence between pesticide-treated and control plots, with a lab analysis finding “[s]eventy-five percent (75%) of pesticide residue was detected in the soil samples,” which includes paraquat dichloride, endosulfan, diazinon, and N-(phosponomethyl)glycine [glyphosate]. This report builds on years of research from higher education institutions worldwide, including participatory research centering applied experiments on farmland, demonstrating the consequences of relying on pesticide-intensive agriculture and land management. The main goal of this report is to “determine the influence of pesticide contamination on the microbial population, physiochemical parameters and pesticide residue of soil of selected farmlands in Otuoke, Bayelsa State, Nigeria.” Researchers document the presence of eleven […]

(Beyond Pesticides, August 29, 2024) The Center for Agriculture and Bioscience International (CABI) earned the 2024 Innovators Award from The Better Cotton Initiative (Better Cotton) for its leadership in developing capacity and expansion of organic standards and practices in the Pakistani cotton sector, according to a press release by Better Cotton. Given the millions of pounds of some of the most toxic chemicals used to produce cotton, and Pakistan being an exporter of $3.5 billion worth of cotton (2021), including $240 million to the U.S. (2022), cotton production is a worldwide contamination problem. The U.S. is currently the fourth largest cotton producer (domestic and export) and the largest cotton exporter in the world, accounting for 30% of all cotton produced, valued at $5.7 billion (2021). The farm value of U.S. organic cotton is $35.55 million (2021). According to the Organic Trade Association, organic cotton comprises approximately 0.95% of global cotton production. “CABI, for its multifaceted work in Pakistan which has included the creation of a national organic agriculture policy for Pakistan that is currently being assessed by the country’s Ministry of Food Security and Research,” the release goes on to discuss the implications of the years-long initiative. “If approved, the policy […]

Image: Art Page submission from Max Sano, “Maryland Farmland“ (Beyond Pesticides, August 27, 2024) A recent entry in the Civil Eats investigative series, “Chemical Capture: The Power and Impact of the Pesticide Industry,” unpacks the troubling coordination between carbon markets, toxic pesticide products, and industrial agriculture to mutually reframe their business models under the guise of climate-smart agriculture. In recent years, powerful agribusiness corporations—including Corteva (chlorpyrifos) and Bayer/Monsanto (glyphosate)—have made significant progress in becoming leading providers of carbon markets based in the United States. Advocates, farmers, and communities view the misrepresentation of carbon offsets and trading as a climate solution in a strategy that undermines proven alternative systems of agriculture and land management (aka organic). The underlying concept of carbon markets began with the emissions trading program as a result of the Kyoto Protocol back in the 1990s. “Emissions trading, as set out in Article 17 of the Kyoto Protocol, allows countries that have emission units to spare—emissions permitted them but not “used”—to sell this excess capacity to countries that are over their targets,” according to the United Nations. Based on Civil Eats’ reporting, Bayer/Monsanto with Climate FieldView and Corteva with its Carbon Solutions program, cite their pesticide products as […]

(Beyond Pesticides, August 13, 2024) With novel methods to provide a big-picture view of the overlap between high pesticide use and cancer incidence across the U.S, a new study has again linked pesticide exposure to a range of cancers. The study by Jacob Gerkin, D.O. and colleagues, “Comprehensive assessment of pesticide use patterns and increased cancer risk,” published in Frontiers in Cancer Control and Society, examines the association between high-pesticide use and cancer diagnoses along with smoking incidence data and the Social Vulnerability Index, a measure used by the Centers for Disease Control and Prevention (CDC) that includes variables such as poverty, poor housing, and exposures to natural disasters and chemical spills. The researchers consider 69 pesticides used in agriculture that are monitored by the U.S. Department of Agriculture. They use U.S. Geological Survey data to map areas of similar crops and pesticide use patterns and incorporate public health data from the CDC to develop their final picture. In terms of threats to health, cancer remains top of mind for most people. Globally, about ten million people die of cancer each year. And while treatments for cancer and survival times have burgeoned over the years, many cancers—particularly colorectal and breast […]

(Beyond Pesticides, July 30, 2024) The U.S. Environmental Protection Agency (EPA) announced on July 15 what it described as a new process for evaluating the risks of spray drift—the migration of pesticides from their target area to off-site zones. According to a statement by EPA Chemical Safety and Pollution Prevention Assistant Administrator Michal Freedhoff, PhD in an Oregon Public Broadcasting story, the agency took the step so that “people don’t have to wait years for the protections they deserve and need.” However, EPA states, “The Agency is not making any changes to its chemical-specific methodology outlined in [its] 2014 document but has decided to extend the chemical-specific spray drift methodology to certain registration actions.” EPA has said, “Spray drift is governed by a variety of factors which govern how much of the pesticide application deposits on surfaces where contact with residues can eventually lead to indirect exposures (e.g., children playing on lawns that are next to treated fields and where residues have deposited).” The new policy will add spray drift evaluation to occasions when the agency receives an application for a new pesticide and when a registered pesticide is intended for a new use or applied to a new crop. […]

(Beyond Pesticides, July 26, 2024) Beyond Pesticides released the latest issue of Pesticides and You this week, a compendium of scientific research on pesticide threats to human and environmental health. The issue is a breathtaking warning from the science community that environmental, health, and labor laws are not protecting the public. Beyond Pesticides says in its introduction that a shift away from toxic pesticide use is urgently needed. Included in this issue are scientific reviews of research reported by Beyond Pesticides in 2023, providing a critique of the independent peer-reviewed literature with a shocking range of adverse effects, including cancer, neurotoxicity, brain effects, reproductive impacts, diabetes and obesity, chronic kidney and liver disease, Parkinson’s, respiratory illness and asthma, learning and behavioral abnormalities, and more, as well as disproportionate harm to people of color. In addition, the science documents pesticides’ catastrophic harm to the ecosystems that sustain life. In total, these dramatic findings call for an end to the use of toxic pesticides, incompatible with respect for living organisms and, to environmental, health, and labor advocates, unconscionable given the availability of viable, cost-effective organic practices. This issue adds to the body of knowledge from two previous issues of Pesticides and You (Transformative Change: […]

(Beyond Pesticides, July 17, 2024) National election results in the United Kingdom (UK) and France in recent weeks have shocked the world amidst concerns of a rising tide of right-wing authoritarianism on the eve of European Parliament election results—trending toward what was initially perceived as a conservative majority earlier in June. With new leadership in some of the biggest economies and policy leaders across the Atlantic, environmental and health advocates are hopeful that this will signal a new momentum to advance the mission of transitioning to a fully organic land management and food system that replaces the status quo reliant on toxic petrochemical-based pesticides and fertilizers that exacerbate the climate crisis, biodiversity collapse, and public health fragility. Citizens of the United Kingdom overwhelmingly voted for the center-left Labour Party, which won an unprecedented margin of 291 seats, winning 412 seats out of the 650 total seats up for grabs. The Conservative Party won just 121 seats, a clear rejection of their nearly fifteen-year leadership position in UK politics. UK-based advocates welcome the news given the Labour Party platform to “ban neonicotinoid pesticides imidacloprid, clothianidin, and thiamethoxam due to their impact on bees,” according to reporting by Politico. Neonicotinoids have long […]

(Beyond Pesticides, June 12, 2024) A study of pesticide contaminated algae finds that the disruption of algal communities has a devastating effect on the health of the aquatic food web. The study findings show that contact with pesticides can result in changes to “algal physiology, causing tissue injury, developmental delay, genotoxicity, procreative disruption, and tissue biomagnification” that alters the dominance of algae species in the environment. This in turn “can impact higher trophic levels and have a domino effect on the aquatic food web. It is possible for biodiversity to disappear, reducing ecosystem stability and resistance to environmental alterations,” the authors state. The study, a worldwide literature review conducted by researchers from India, South Korea, and Saudi Arabia, appears in Aquatic Toxicology.  The health of aquatic ecosystems is at risk with indirect effects on nontarget species from pesticides in the environment. This includes impacts on species of fish, invertebrates, microbial communities, and marine mammals. In explaining the importance of extensively studying effects of pesticides, the researchers note, “Different pesticide classes have different chemical structures, which define their modes of action and affect how they interact with both target and nontarget organisms.” Because of this, the range of effects seen from […]

(Beyond Pesticides, June 10, 2024) Expanding the planting of genetically engineered crops is the major focus of “The Coordinated Framework for the Regulation of Biotechnology – Plan for Regulatory Reform under the Coordinated Framework for the Regulation of Biotechnology” (Framework), released in May by three federal agencies. In its Framework, the U.S. Department of Agriculture (USDA), the Food and Drug Administration (FDA) and the U.S. Environmental Protection Agency (EPA) use the words “exempt” or “exemption” in reference to federal safety regulations 21 times. Then, another 21 times the agencies identify their efforts to “streamline” the process for bringing genetically engineered “plant-incorporated protectants” (PIPs) to market. Without including the word “resistance” even once, the Framework advances the interests of the biotech and allied industries, ignoring the serious scientific issues regarding health and environmental effects and the economic failure for farmers facing crop loss. Meanwhile, the issue of resistance is not new to EPA, which has for years acknowledged the resistance problem despite allowing continued weed resistance to weed killers used with herbicide-tolerant crops and insect resistance to the pesticides incorporated into plants.   >> Tell USDA, FDA, and EPA to replace agricultural provisions in the Framework with policies that discourage GE crops […]

(Beyond Pesticides, May 31, 2024) Among the many promises that have been made by agribusiness to farmers and consumers, the glories of crops genetically engineered (GE) to resist pests stand out. GE tools—genes—were touted as “natural,” and promised to reduce the use of toxic pesticides. The first such plants incorporating DNA or RNA from other organisms hit the market in the 1990s. Today more than 70% of all GE organisms are engineered to tolerate herbicides, and the overwhelming majority of corn, soybean and cotton varieties are engineered to to be toxic to insects. See Beyond Pesticides’ backgrounder on GE here. Despite a dramatic increase in the use of herbicides and the fast development of weed and insect resistance to plant incorporated pesticides, this month the U.S. Department of Agriculture (USDA), the Food and Drug Administration (FDA) and the U.S. Environmental Protection Agency (EPA) jointly released a document entitled “The Coordinated Framework for the Regulation of Biotechnology – Plan for Regulatory Reform under the Coordinated Framework for the Regulation of Biotechnology.” It responds to a 2022 executive order by President Biden to “accelerate biotechnology innovation” and “support the safe use of biotechnology products” by using a “science- and risk-based, predictable, efficient, […]

(Beyond Pesticides, May 29, 2024) A study from the Academy of Biology and Biotechnologies and the Federal Rostov Agricultural Research Centre adds to the body of science linking pesticide use with negative impacts on soil health and bacterial communities. Antibiotic-resistance genes (ARGs), considered a class of pollutants, are found in certain types of bacteria and can spread through the environment and subsequently to humans and animals. This study, performed by researchers and soil experts, found an increase in specific bacterial families that host ARGs with exposure to pesticides.  The study aims to identify the role of agricultural soils in ARG transfer and to assess the presence and prevalence of bacterial families with and without exposure to fertilizers and pesticides. Since soil serves as a habitat for a wide range of bacteria, including many that are resistant to antibiotics, analyzing the organisms within soil samples is an indicator of overall environmental health. Agricultural soils are essential in food production, and as this study states, “[I]ntensive exploitation of such soils implies the widespread use of various chemical plant protection products (insecticides, herbicides, fungicides) and mineral fertilizers, which contribute to pollution and a decrease in soil quality.”   Within this field study, there is […]

(Beyond Pesticides, May 14, 2024) As research continues to emerge on the value of organic farming, U.S. Congress debates its future as Farm Bill negotiations have been stalled for months. Recent studies published within the past few months show the significance of organic agriculture’s support of fungal and microbial life, which is essential to soil health. Meanwhile, last week the Democrat-led Senate and Republican-led House of Representatives presented their respective visions to amend the 2024 Farm Bill. The office of U.S. Senator Debbie Stabenow (D-MI), chair of the Senate Agriculture Committee, released an initial Senate framework for the (now 2024) Farm Bill. At the same time, U.S. Representative Glenn Thompson (R-PA), chair of the House Agriculture Committee, released an outline of the House version, then followed up with more details. While the Senate Democratic proposal includes more robust support for expanding and strengthening organic product supply chains and domestic production, the House Republican support for organic land management principles and practices demonstrates that the Farm Bill could recognize, across the political spectrum, its economic, ecological, and public health benefits in the United States. Despite this, a growing coalition of advocates is alerting the public and members of Congress that the […]

(Beyond Pesticides, May 7, 2024) The marginal user costs (MUC) of pesticide resistance for chemical-intensive farmers and the pest management industry are significantly affected by pesticide costs, density dependence (growth rate of a pest population impacted by its density), and dominant genetic mutations that cause resistance, according to a novel study published in Journal of the Agricultural and Applied Economics Association. Although the authors believe that integrated pest management (IPM) can be fine-tuned based on these findings, many advocates believe that these findings in fact underscore the importance of eliminating toxic pesticide use amidst compounding climate, biodiversity, and public health crises—which many IPM strategies do not adequately address. As the costs of petrochemical-based pesticides increase, organisms identified as pests continue to increase in population density as global and regional temperatures dually increase. Organic agriculture, and organic land management principles more broadly, are an economically and ecologically advantageous leap ahead in transitioning to a food system that moves beyond the status quo that poisons people and the planet. “This paper seeks to develop a better understanding of how the user costs of resistance are potentially determined by the interactions of heterogeneous bioeconomic factors that vary by context,” say the study authors. […]

(Beyond Pesticides, April 25, 2024) In a study from earlier this year, “Pesticides: An alarming detrimental to health and environment,” scientists compiled research from 154 articles regarding pesticide use and the adverse effects they have on the environment and human health. Among the effects of the harmful pesticides described is genotoxicity—the alteration of genetic material that results in the mutations in DNA that cause cancer.  The authors state that “genotoxins are mutagenic chemicals, and exposure to them increases the risk of developing tumors, hormonal changes, DNA damage, and changes in the ovaries and eggs, all of which leading to cancers… The risk of DNA damage surges with increased genotoxicity in people exposed to pesticides.” In addition, the National Institute of Health states that all “pesticides are highly biologically active chemicals. They may interact with DNA and damage its structure.” Despite these documented risks, pesticide use continues to surge.  While phased out to a considerable extent after being widely used in agriculture and residential areas, organochlorine pesticides (OCPs) like dichlorodiphenyltrichloroethane (DDT) or its breakdown compound dichlorodiphenyldichloroethylene (DDE) continue to show up as residues in the environment and food supply. Symptoms in humans that have been exposed to these chemicals include: seizures, […]

(Beyond Pesticides, March 20, 2024) A report by CBAN unpacks the ecosystem and wildlife health impacts of genetically engineered (GE) corn in the context of Mexico’s 2023 decision to stop its importation into the country. The phase out of genetically modified (GM) corn imports into Mexico was immediately challenged by the U.S. and Canadian governments as a trade violation under the 2020 U.S.-Mexico-Canada Agreement (USMCA), which replaced the North American Free Trade Agreement (NAFTA) as the primary vehicle for North American trade policy. In August 2023, the U.S. Trade Representative set up a dispute settlement panel under USMCA to stop Mexico from going forward with its ban. There has been no public update from the Office of the U.S. Trade Representative as of this writing. The CBAN report highlights the scientific rationale underpinning Mexico’s decision to “safeguard the integrity of native corn from GM contamination and to protect human health” with this ban. In 2020, Mexico announced a four-year phase-out of the weed killer glyphosate, which along with other petrochemical herbicides is integral to GM corn production. When Mexico’s Minister of the Environment announced the phase-out, he said it is part of an effort to transform the country’s food system […]