(Beyond Pesticides, July 29, 2022) Perhaps attempting to capitalize on the recent U.S. Supreme Court decision limiting the U.S. Environmental Protection Agency’s (EPA’s) ability to regulate carbon emissions, Senator Roger Marshall of Kansas (R) has filed a bill in the Senate that seeks to limit the agency’s ability to regulate pesticide use. The so-called EPA Transparency for Agriculture Products Act of 2022 is touted, on Senator Marshall’s website, as “a comprehensive bill to prevent . . . EPA . . . from overregulating essential pesticides that the ag industry heavily depends upon.” In truth — and perversely, given that he is a medical doctor — the bill aims to provide more license to use toxic pesticides that harm human health, the environment broadly, and ecosystems already under assault from toxic, synthetic pesticides and fertilizers, habitat destruction, and climate change. Couched in language about “feeding the world,” the bill’s central concern seems to be financial impacts or challenges that farms (a good portion of which, let us remember, are giant, well-resourced agribusinesses) may face because of EPA pesticide regulations. Those regulations, of course, are promulgated by the agency to protect people, organisms, ecosystems, and natural resources from harmful impacts and risks […]

(Beyond Pesticides, June 21, 2022) June 20-24 is Pollinator Week, during which we recognize—and take action to protect—this important ecosystem link. Pollinators––bees, butterflies, birds, bats, and other organisms––make a critical contribution to plant health, crop productivity, and the preservation of natural resources, but their existence is threatened by their pesticide-contaminated habitat. Pesticides have consistently been implicated as a key contributor to dramatic pollinator declines. Of the 100 crop varieties that provide 90% of the world’s food, 71 are pollinated by bees. Honey bees alone pollinate 95 kinds of fruits, nuts and vegetables, such as apples, avocados, almonds, and cranberries. Take action to protect pollinators. Providing protection for pollinators also protects the ecosystem in which they live. That protection requires eliminating harm as well as providing safe habitats where they can live and reproduce.  Provide organic habitat on your own property and encourage your town to go organic. Since plant starts in many garden centers across the country are grown from seeds coated with bee-toxic neonicotinoid pesticides, or drenched with them, Beyond Pesticides has compiled a comprehensive directory of companies and organizations that sell organic seeds and plants to the general public. Included in this directory are seeds for vegetables, flowers, and herbs, as well as […]

(Beyond Pesticides, May 27, 2022) In a U.S. Environmental Protection Agency (EPA) court document filed on May 16, the agency signaled potential changes to the labeling it requires for “over the top” (OTT, or post-emergent) herbicides containing dicamba, a very problematic pesticide. The filing — in U.S. District Court for the District of Arizona, where EPA currently faces litigation about its 2020 dicamba registrations — comes as a result of Bayer, Inc.’s March 2022 proposed amendments to EPA registration for its XtendiMax herbicide, which contains dicamba and glyphosate. Beyond Pesticides has covered the dicamba saga for years, including the EPA Office of the Inspector General’s critical 2021 report citing an abandonment of science and assault on agency integrity for EPA’s dicamba decisions during the Trump years. Dicamba has been linked to cancer, reproductive effects, neurotoxicity, birth defects, and kidney and liver damage. It is toxic to birds, fish, and other aquatic organisms, and is known to leach into waterways after application. Dicamba also causes serious damage to non-GE (genetically engineered), non-target plants, damaging habitat and food sources for various organisms, especially for birds and insects. According to Progressive Farmer, EPA is currently considering some dicamba use restrictions after Bayer submitted them to […]

(Beyond Pesticides, May 12, 2022) A report published in Environmental Health finds that exposure to environmentally relevant concentrations of pesticides can alter gut microbial communities, as demonstrated through fecal samples. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood and urine samples. Ample evidence demonstrates that environmental contaminants, including pesticides, negatively affect the human mouth and gut microbes. However, fecal samples provide an accurate representation of the microbial community existing in the gut. These toxicants can alter hormone metabolism, which adversely affects health outcomes. Adverse health effects of environmental contaminants include reproductive and developmental defects, diabetes, cardiovascular disease, liver disease, obesity, thyroid disorders, and improper immune operation. Although studies show how chemical exposures affect human health, more research is now questioning how these toxic chemicals influence gut health. Therefore, studies like these highlight the importance of evaluating how chemical contaminants deregulate normal bodily function through microbiome changes. The report notes, “Our results highlight the need for future dietary intervention studies to understand effects of pesticide exposure on the gut microbiome and possible health consequences.” Researchers examined dietary exposure to 186 common pesticide residues in the fecal excrement to determine impacts on the microbiome among 65 twins in the United Kingdom. […]

(Beyond Pesticides, May 10, 2022) Widespread weed resistance on chemical corn and soybean farms is leading farmers to till their fields more often, significantly increasing greenhouse gas (GHG) emissions. These findings were published late last month in the journal Nature Food by a team of Iowa State University researchers. With agricultural practices accounting for roughly 10% of U.S. GHG emissions, and 25% of worldwide releases, farming practices that preserve soil health and sequester GHGs are essential for the future of food production. Tillage is a farming practice that can provide a range of benefits for crop production, but only in the right conditions. A range of tillage practices exist, ranging from yearly conventional tillage, where most crop residue is plowed into the soil, to conservation tillage where some residue remains, and no-till systems where the soil remains covered. Repeated tillage causes significant harm to soil structure and biology, and result in erosion and the release of GHGs like carbon dioxide, methane, and nitrous oxide from soil into the atmosphere. The harms of tillage have led both chemical and organic farmers toward no-till or reduced tillage systems. Organic no-till farming, as practiced by farming groups like the Rodale Institute, employs the […]

(Beyond Pesticides, April 28, 2022) A study in Environmental Research finds that glyphosate’s primary metabolite (breakdown product), aminomethylphosphonic acid (AMPA), induces DNA damage through oxidative stress among subpopulations of primary school children. Although pyrethroid and chlorpyrifos metabolites can induce oxidative stress, this study is the first to investigate AMPA’s association with adverse health effects, rather than solely the effects of the active ingredient, glyphosate, in Roundup and other formulations. Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulations, readily contaminating soil, water, food, and other resources. Chemical use has been increasing since the inception of crops genetically modified to tolerate glyphosate. However, studies demonstrate glyphosate is among the most prevalent pesticide contributors to human, biotic, and ecosystem harm. According to research, herbicide toxicity to invertebrates has doubled since 2004. Although research links glyphosate exposure to cancer, specifically non-Hodgkin lymphoma, much less research considers the effects that metabolites have on children who are more vulnerable to chemical exposure. Ecological and health risk assessments primarily focus on active ingredients in pesticide products, overlooking the potential impacts of metabolites. Thus, studies like these highlight the need to assess the implications of metabolite exposure to protect human, animal, and environmental health. The study notes, “Our […]

(Beyond Pesticides, April 5, 2022) A meta-analysis by the Federal University of Technology – Paraná finds the herbicide 2,4-D causes indiscriminate harm, increasing the mortality rate among exposed animals. The severity of chemical exposure relies on species sensitivity, exposure rate, and lifecycle stage. However, commercial formulations of 2,4-D, commonly used in the environment, prompt a higher species mortality rate than technical (pure) 2,4-D alone. Like many other common herbicides such as glyphosate, 2,4-D has global uses that allow the chemical to accumulate in the environment, including soils, waterways, and tissues of non-target species. Therefore, meta-analyses like this help local and government officials make holistic decisions regarding environmental contaminants that incorporate conclusions from various studies. Using the Web of Science and Scopus databases, researchers compiled various studies (or meta-analyses) on the lethality of 2,4-D in different animal species (e.g., vertebrates, invertebrates). Researchers evaluated each study regarding the mortality rate of control and experimental groups, animal sensitivity to chemical exposure during a specific life stage, chemical formulation (e.g., commercial or technical), and exposure routes causing mortality. The analysis demonstrates that vertebrates experience higher mortality rates from 2,4-D exposure, with fish and birds presenting the highest mortality rate. Regarding life stages, larval and adult […]

(Beyond Pesticides, March 10, 2022) Glyphosate and glyphosate-based herbicides (GBH) like Roundup® induce DNA damage and alter biological mechanisms (gene regulatory microRNAs [miRNAs or miRs]) associated with cancer development. According to the study published in Toxicological Sciences, DNA damage mainly occurs through oxidative stress from GBH exposure. Moreover, DNA damage and other biological mechanisms that cause carcinogenicity (cancer) occur at doses assumed “safe” by pesticide regulators such as the U.S. Environmental Protection Agency (EPA). Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulas, not just Bayer’s (formerly Monsanto) Roundup®. The use of this chemical has been increasing since the inception of crops genetically modified to tolerate glyphosate over two decades ago. The toxic herbicide readily contaminates the ecosystem with residues pervasive in food and water commodities. In addition to this study, literature proves time and time again that glyphosate has an association with cancer development, as well as human, biotic, and ecosystem harm.  Study lead author Michael Antoniou, Ph.D., cautions, “Our results are the first to simultaneously show glyphosate and Roundup toxicity in a whole mammalian animal model system and provide a mechanism – oxidative stress – by which DNA damage has been observed in other systems, such as mammalian […]

(Beyond Pesticides, March 4, 2022) An article in My London reported by Finn Byrne, finds labeling on conventionally grown fruits and vegetables marked as non-vegan. The non-vegan label shocked many shoppers who buy the produce with chemical-intensive practices, as fruits and vegetables are inherently vegan. However, pesticides used in the production of fruits and vegetables render these foods non-vegan because of the harm that pesticides cause to animals and since a wax coating on fruits and vegetables made of shellac, a resin secreted from female lac beetles and thus non-vegan. Recent studies indicate plant-based diets can mitigate excessive pesticide use and exposure if they are organically grown. However, a plant-based diet reliant on pesticides does little to lessen the health and ecological effects of conventional agriculture. Fungicides are ubiquitous in agricultural and residential settings puts human and animal health at risk. Exposure to fungicides can manifest adverse health effects, including reproductive dysfunction, birth/developmental effects, kidney/liver damage, and cancer. Several researchers find that fungicide use promotes more drug-resistant fungal infections in humans as these fungicides are structurally similar to medical antifungal medications. After investigating fruits and vegetables at various United Kingdom (UK) grocery stores (i.e., Tesco, Morrisons, and Marks and Spencer), the report finds fungicides imazalil and propiconazole present […]

(Beyond Pesticides, March 1, 2022) A report by the Independent finds chemical-intensive farming of crops for animal feed puts thousands of endangered species at risk. U.S. farmlands use more than 235 million pounds of pesticide (i.e., herbicides and insecticides) solely for animal feed production, many of which are highly hazardous pesticides (HHPs). Several HHP hazard categories include acutely toxic, chronic health hazards, and environmental hazards. Therefore, animal feed production intensifies global pollution, increases pesticide exposure, and degrades human, animal, and ecological health.  Although the report demonstrates a need to eliminate toxic pesticide use for the sake of human, animal, and ecosystem health, it will take more than eliminating the worst chemicals to address the impending biodiversity collapse and the climate crisis. Experts highlight the need for an urgent shift to organic land and agricultural management practices. The study notes, “These pesticides are taking a toll on our environment and biodiversity. Endangered species like the highly imperiled whooping crane, monarch butterflies, all species of salmon, the rusty-patched bumble bee, the San Joaquin kit fox, and the northern long-eared bat, as examples, all face significant threats from industrial agricultural operations and the chemicals applied. In order to conserve biodiversity and better protect vulnerable species and their habitats, […]

(Beyond Pesticides, February 23, 2022) Fungicide use in agriculture is driving the spread of multi-fungicide resistant human pathogens, finds a recent study conducted by scientists at the University of Georgia. While this occurrence has long been an assumption based on the rampant overuse of fungicides in chemical-dependent farming, scientists have now found clear evidence linking the development of widespread fungal resistance to farming practices, rather than health care use. Despite strong evidence that commonly used synthetic pesticides in chemical-intensive farming are driving resistance that threatens human health on a global scale, the U.S. government has not only failed to take action, it has fought against international efforts to slow the crisis, at the behest of the agrichemical industry.   Scientists focused their research on Aspergillus fumigatus, a common mold that can infect humans and cause aspergillosis. Although some have problems with mild sensitivity to the fungus, virulent infections called invasive aspergillosis can occur in immunocompromised individuals and are on the rise. Cases of invasive aspergillosis increased 3% per annum between 2000 and 2013, and roughly 300,000 worldwide are diagnosed each year. On both farms and in human medical settings, antifungal compounds called azole fungicides are used in attempts to kill […]

(Beyond Pesticides, February 15, 2022) A synthetic weed killer linked to cancer, endocrine (hormone) disruption, reproductive harm and birth defects can be found in the bodies of 1 in 3 Americans, according to research published in Environmental Health by scientists at George Washington University. The chemical in question is not glyphosate (though current data indicate similar results are likely) but 2,4-D, an herbicide that is increasingly used when weeds growing near genetically engineered  (GE) crops have developed resistance to the repeated use of Roundup and other glyphosate-based weed killers. “Our study suggests human exposures to 2,4-D have gone up significantly and they are predicted to rise even more in the future,” Marlaina Freisthler, a PhD student and researcher at the George Washington University, said. “These findings raise concerns with regard to whether this heavily used weed-killer might cause health problems, especially for young children who are very sensitive to chemical exposures.” Researchers conducted their analysis based on data from the National Health and Nutrition Examination Survey, which includes urinary concentrations of 2,4-D from 14,395 participants spanning 2001 to 2014. Between those years, the use of 2,4-D increased rapidly from its relative low point at the beginning of the century. “Roundup […]

(Beyond Pesticides, December 10, 2021) In a win for pollinators, a California Superior Court has issued a ruling that sulfoxaflor, a systemic pesticide that is “field legal” but “bee lethal,” can no longer be used in the state. The suit was brought by the Pollinator Stewardship Council and the American Beekeeping Federation. The ruling of the Superior Court of the State of California for Alameda County finds that the argument of the petitioners — that sulfoxaflor approval decisions by the California Department of Pesticide Regulation (DPR) violated the California Environmental Quality Act (CEQA) — is valid. Eliminating this highly bee-toxic pesticide from use in the state is expected to protect not only native bees and other pollinators (including Monarch butterflies in early Spring), but also, the many millions of managed-colony bees that are transported to California for pollination of almond and other crops. The suit was filed against DPR, Corteva inc., Dow Agrosciences LLC, the Siskiyou County Department of Agriculture, and James E. Smith as Siskiyou County Agricultural Commissioner. Having found for the petitioners’ request for a Writ of Mandate (a court order requiring a lower court or public authority to perform its statutory duty), the court instructed the petitioners to […]

  (Beyond Pesticides, November 24, 2021) On Thanksgiving, thank you for being a part of Beyond Pesticides and sharing and contributing to the vision necessary to protect the web and fragility of life. We believe that there is no time like Thanksgiving to think about how we can more effectively join together as families and communities across divisions and different points of view to find a common purpose in protecting the health of the environment and all that inhabit it. Unfortunately, there are a host of pesticides, genetically engineered materials, and others in conventional Thanksgiving foods that not only impact human health, but threaten the environment. With far too many adverse health and ecological effects associated with toxic chemicals, organic practices are viable solutions to mitigate pesticide contamination and subsequent exposure. Read on as we consider the range of challenges we must confront, and the solutions that can bring us all together. The Climate As climate impacts grow, an increase in uses of synthetic pesticides in agriculture is likely — because of waning efficacy (pesticide resistance) of these compounds, and mounting pest pressure (i.e., increasing insect population and metabolism). Production of pesticides contributes to greenhouse gas emissions gas (e.g., nitrous […]

(Beyond Pesticides, November 23, 2021) The U.S. Environmental Protection Agency (EPA) announced, in mid-October, a revision of its guidance on the evaluation of antimicrobial pesticides used against Candida auris (C. auris). This pathogen is a type of fungus (a yeast) that can cause serious infection, and can spread readily among patients and staff in hospitals and other congregate healthcare settings (such as nursing homes). C. auris has developed resistance to what used to be the therapeutic impacts of major antifungal medications. (Resistance is a major and growing problem in healthcare and in agriculture, with the latter exacerbating the former.) Another moving part in this unholy development of “chemical compounds no longer working” is EPA’s failure to assess the efficacy of any pesticides that are not used for public health purposes; for example, EPA evaluates the efficacy of only those antimicrobial compounds whose use patterns classify them as human-health-related. This failure to evaluate efficacy of all other pesticide products leaves many people in the dark about whether what they may be using actually works — never mind the potential risks associated with that use. The antifungal medications that have been used for many years to treat Candida infections often no longer work for C. auris; […]

(Beyond Pesticides, November 12, 2021) Omnivorous readers may have encountered an article, in the November 15 issue of The New Yorker magazine, titled — at best misleadingly, and certainly sensationally — “The Great Organic-Food Fraud.” The subhead comports with the tone of the headline: “There’s no way to confirm that a crop was grown organically. Randy Constant exploited our trust in the labels — and made a fortune.” The piece, by Ian Parker, tells a complex tale of the machinations of dishonest and greedy people who saw, in the commerce in organic grains, an opportunity to misrepresent nonorganic crops as organic and make a boatload of money in doing so. What the article fails to do is render any comprehensive picture of how National Organic Program certification and inspection work, and the underlying principles, values, and standards in federal law (the Organic Foods Production Act), nor does it review either the benefits of organic agriculture broadly or the massive harmful impacts of conventional, chemical-intensive agriculture in the U.S. Beyond Pesticides provides ballast, in this Daily News Blog article, to the failings of the New Yorker article and the damage it might do to the organic movement. It is worth noting […]

(Beyond Pesticides, October 28, 2021) A study published in Frontiers in Environmental Science finds the popular herbicide glyphosate negatively affects microbial communities, indirectly influencing plant, animal, and human health. Exposure to sublethal concentrations of glyphosate shifts microbial community composition, destroying beneficial microorganisms while preserving pathogenic organisms. Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulas, including Bayer’s (formerly Monsanto) Roundup®. The use of this chemical has been increasing since the inception of crops genetically modified to tolerate glyphosate over two decades ago. The toxic herbicide readily contaminates the ecosystem with residues pervasive in both food and water commodities. In addition to this study, the scientific literature commonly associates glyphosate with human, biotic, and ecosystem harm, as a doubling of toxic effects on invertebrates, like pollinators, has been recorded since 2004. The authors caution, “[O]utbreaks of several animal and plant diseases have been related to glyphosate accumulation in the environment. Long-term glyphosate effects have been underreported, and new standards will be needed for residues in plant and animal products and the environment.” With an increasing number of reports on the relationship between glyphosate and human health, including potential effects on the human gut microbiome, advocates are calling on global leaders to eliminate chemical […]

(Beyond Pesticides, October 13, 2021) Pesticide use in conventional chemical-intensive farming is so pervasive that weeds are developing resistance to herbicides they have never encountered before. According to research published in Plant and Cell Physiology and New Phytologist, the notoriously difficult-to-control weed waterhemp (Amaranthus tuberculatus) is outpacing commercial crops in its ability to detoxify after herbicide exposure. “This is probably the first known example where waterhemp has evolved a detox mechanism that a crop doesn’t have. It’s using a completely different mechanism, adding to the complexity of controlling this weed,” says Dean Riechers, PhD, study co-author and professor at University of Illinois. Researchers found waterhemp resistant to the chemical syncarpic acid-3 (SA3). SA3 is one of the earliest versions of a 4-Hydroxyphenylpyruvate dioxygenase (HPPD) inhibiting herbicide. HPPD inhibiting herbicides, which include herbicides like isoxaflutole and mesotrione, are selective (ie plant-specific) and break down amino acids that are required for plant growth and development. Corn generally tolerates HPPD-inhibiting chemicals, detoxifying them through different channels depending upon the specific type of HPPD herbicide. Weeds that grow in and around corn fields where these chemicals are regularly sprayed, like waterhemp, have likewise evolved the ability to detoxify HPPD-inhibitors, mostly mimicking the process that […]

(Beyond Pesticides, October 8, 2021) Taking a page from the playbook of Trump Administration Secretary of Agriculture Sonny Perdue, the current secretary, Tom Vilsack, used a September G20 summit in Italy to target the European Union’s “Farm to Fork” (F2F) strategy, a part of its European Green Deal. Mr. Perdue had said that F2F is “more . . . ‘political science’ than demonstrated agricultural science”; Secretary Vilsack called it “a path very different from the one the U.S. is pursuing.” The F2F initiative aims to transition the EU to a sustainable food system such that it also achieves significant mitigation of climate change. But Mr. Vilsack chose to counter the F2F efforts by promoting an “alternative strategy” — under the moniker “Coalition for Productivity Growth” — through which “other nations pledge not to follow the European path on farm policy.” He has described this alternative, U.S.-led strategy as “a market-oriented, incentive-based, voluntary system [that] is effective” at slashing agricultural carbon emissions. Climate, pesticide, organics, and other environmental and health advocates, including Beyond Pesticides, are troubled by these actions. Mother Jones poses the central question in the headline of its September 30 article: Why is Secretary Vilsack So Afraid of a Plan to Cut […]

(Beyond Pesticides, September 16, 2021) A study published in Chemosphere finds persistent organic pollutants (POPs), including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs), are present in the serum and placenta of pregnant mothers, as well as multiple fetal organs. Many studies indicate prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. However, this study is one of the first to demonstrate the presence of chemical toxicants in fetal tissue that are not present in maternal serum or placental samples. Prenatal development is one of the most vulnerable periods of exposure when the fetus is most susceptible to the harmful effects of chemical contaminants. Therefore, studies like these help government and health officials better identify fetal exposure contaminants and subsequent health concerns otherwise missed by current chemical monitoring methods. The researchers note, “These findings call for further evaluation of the current matrices used to estimate fetal exposure and establish a possible correction factor for a more accurate assessment of exposure in utero. We disclose the full data set on individual exposure concentrations to assist in building in silico models for prediction of human fetal exposure to chemicals.” Several studies associate early-life exposure to toxic chemicals […]

(Beyond Pesticides, September 2, 2021) A McMaster University (Canada) study demonstrates exposure to the recently banned, commonly used insecticide chlorpyrifos promotes obesity development, even at low doses. Obesity generally occurs following a caloric imbalance between food intake, absorption, and energy expenditure. Although various factors can promote obesity, researchers suggest environmental toxicants like chlorpyrifos play a role in obesity development through protein/enzyme suppression. According to the Center for Disease Control, 42 percent of the U.S. population is obese and at risk for type two diabetes, cardiovascular (heart) disease, stroke, several cancers, and other critical health issues. Therefore, research like this highlights the significance of investigating how toxic chemical exposure can impact health to prevent adverse disease outcomes. Researchers note, “These studies suggest that the effects of environmental toxicants on the development of obesity may have been underestimated as all studies to date have been conducted in mice housed at RT [room temperature]. Future studies examining the mechanisms driving reductions in β-AR [beta adrenergic receptors] signaling and whether there are associations between BAT [brown adipose tissue] metabolic activity and CPF [chlorpyrifos] in humans will be important.” Several environmental pollutants have links to obesity development via the effects on gut health, endocrine (hormone) and metabolic system, […]

(Beyond Pesticides, August 26, 2021) A recent study published in Environmental Research demonstrates that exposure to the herbicide glyphosate and its breakdown product reduces pregnancy length, increasing the risk of preterm birth. Preterm births occur when a fetus is born early or before 37 weeks of complete gestation. Premature births can result in chronic (long-term) illnesses among infants from lack of proper organ development and even death. Birth and reproductive complications are very common among individuals exposed to environmental toxicants, like pesticides. Considering the Center for Disease Control (CDC) reports the preterm birth rate is increasing annually, studies like this can help government and health officials safeguard human health by assessing adverse health effects following prevalent chemical exposure. The study notes, “Given the prevalent and rising exposures to glyphosate and GBHs [glyphosate-based herbicides], confirmatory studies are needed to explore reproductive effects of glyphosate and GBHs to re-assess their safety on human health and to explore possible programming consequences to lifelong health.” GBHs are the most commonly used herbicides, readily contaminating soil, water, and food globally. Although GBHs’ ubiquitous nature has been linked to carcinogenic effects, specifically non-Hodgkin lymphoma, much less research considers exposure effects on reproductive health. The study’s scientists aimed to examine the relationship […]

(Beyond Pesticides, July 1, 2021) Yellow fever mosquitoes (Aedes aegypti) are evolving resistance to the pyrethroid insecticide permethrin, according to a study published by Colorado State University, highlighting the need to adopt ecologically-based mosquito management. Widespread, intensive use of the pesticide in mosquito control has allowed genetic mutations to persist among these mosquito populations, causing subsequent resistance to permethrin. Pyrethroids are one of the few remaining classes of insecticides available to control yellow fever mosquitos, and resistance threatens the ability to prevent disease outbreaks with chemical-intensive methods. Yellow fever mosquitoes are a vector for numerous untreatable diseases in humans, including dengue, chikungunya fever, and Zika viruses. Hence, this study highlights the significance of addressing pest resistance to pesticide control, particularly to mitigate disease exposure and effects. The researchers note, “This knowledge can help scientists understand how mosquitoes have evolved resistance and when a population can no longer be controlled with permethrin. This understanding will be necessary to develop tools to support future insecticide management strategies.” Researchers sequenced the genome of resistant and knockdown (either recovered or dead) mosquitoes after permethrin exposure using a bottle bioassay. The aim was to identify genomic variants/biomarkers associated with specific resistance mechanisms. Two common pyrethroid resistance mechanisms occur among […]