(Beyond Pesticides, June 11, 2025) Researchers developed a novel tool* in a recent study published in Nature Communications this year that successfully creates a map of the “pesticide-gut microbiota-metabolite network,” identifying “significant alterations in gut bacteria metabolism.” While the study authors acknowledge that this is not a complete map, since they selected specific pesticides and bacterial partners, the research adds to the body of peer-reviewed scientific literature that underscores the relationship between pesticide residues and human gut health. Organic farmers, as well as any land steward invested in agroecological practices and soil health, understand that microbial life (both in the body and in the soil) is dangerously undermined by the status quo of chemical-intensive land management. Background and Methodology The researchers leverage mass spectrometry to test metabolite (metabolomics) and lipid (lipidomics) relationships with pesticide residues, as well as an in vivo mouse model. *The map itself is a form of computational biology, which advocates have warned could be a false solution if not accompanied by other proven scientific methods. See here for analysis by the Natural Resources Defense Council on risks of unproven methods such as New Approach Methodologies [NAMs]. All major phylogenetic (“evolutionary relationships among biological entities”) groups are […]

(Beyond Pesticides, June 3, 2025) Chemical contaminants in wastewater have long been of concern, especially given the significant costs of upgrading wastewater treatment facilities to remove existing and emerging chemicals. In advancing chemical safety, one of the many regulatory determinations that Beyond Pesticides advocates for, prior to the allowance of any toxic chemical use, is the establishment of a realistic cleanup or disposal strategy. Yet, a plethora of petrochemical pesticides flood the market and contaminate the air, soil, water, and crops before poisoning humans and wildlife. A study in the Journal of Environmental Chemical Engineering uses the detectable levels of metabolites (breakdown products) of pesticides in wastewater to gauge exposure to populations living near flower bulb fields throughout the Netherlands. Wastewater samples were collected from five wastewater treatment plants (WWTPs) located in different parts of the Netherlands, with two of the locations (Tollebeek and Lisse) located near flower bulb fields and the other three representing control areas. The study finds that higher levels of chemicals correlate with proximity to agricultural fields and present a heightened health risk. The authors describe wastewater-based surveillance (WBS) as a complementary approach to human biomonitoring that they use “to assess the spatial differences in human […]

(Beyond Pesticides, May 1, 2025) Pesticides by themselves are a grave threat to global health. As is global warming. As is antibiotic resistance. Each of these problems has to be analyzed in its own silo to reveal the mechanisms driving its dynamics. But eventually, it must be acknowledged that they actually converge. A common soil arthropod has clearly illustrated how this convergence creates synergistic effects: warming increases pesticide toxicity; pesticide toxicity triggers antibiotic resistance; antibiotic resistance spreads through horizontal gene transfer (movement through the environment to people) and predation. The consequences, not yet fully understood, are nevertheless emerging from accumulating research. A study published in the Journal of Hazardous Materials by scientists at six Chinese universities and research centers examines the convergence in springtails (Folsomia candida)—tiny insect-like animals that live in soils worldwide and are commonly used as laboratory subjects. The researchers exposed springtails to the neonicotinoid insecticide imidacloprid at three concentrations and three temperatures. In addition to measuring the springtails’ direct mortality, the researchers also investigated the microbes in the animals’ guts, checking for expression of genes involved in antibiotic resistance. The evidence is unequivocal: imidacloprid exposure at a soil temperature consistent with current and expected warming (30°C, or […]

(Beyond Pesticides, March 3, 2025) When the United Nations (UN) adjourned the fifth session of the Intergovernmental Negotiating Committee to develop an international legally binding instrument on plastic pollution, including in the marine environment, Inger Andersen, executive director of the United Nations Environment Programme (UNEP), said, “The world’s commitment to ending plastic pollution is clear and undeniable.” She continued, “Here in Busan [Korea], talks have moved us closer to agreeing on a global legally binding treaty that will protect our health, our environment, and our future from the onslaught of plastic pollution.” In March 2022, the UN Environment Assembly adopted UNEA Resolution 5/14 entitled “End plastic pollution: Towards an international legally binding instrument.”  With the Trump Administration shutting down environmental programs and exiting from collaborative international environmental agreements, the work of the world community has taken on elevated importance, given the urgency of health, biodiversity, and environmental crises; so, too, has the work going on at the state level and in local communities across the United States. The interconnectedness of the pesticide and plastic problems was brought into focus recently with a scientific review of articles showing elevated pesticide hazards linked to plastic contamination. A literature review in Agriculture, covering over 90 scientific […]

(Beyond Pesticides, February 25, 2025) A literature review of over 90 scientific articles in Agriculture documents microplastics’ (MPs) increase in the bioavailability, persistence, and toxicity of pesticides used in agriculture. The interactions between MPs and pesticides enhance the threat of pesticide exposure to nontarget organisms, perpetuates the cycle of toxic chemical use, and decreases soil health that is vital for productivity. “The increasing presence of MPs in agricultural ecosystems has raised concerns about their impact on pesticide bioavailability, efficacy, and environmental behavior,” says study author Kuok Ho Daniel Tang, PhD, a global professor in the Department of Environmental Science at the University of Arizona. He continues, “These synthetic particles interact with pesticides through adsorption and desorption processes, altering their distribution, persistence, toxicity, and uptake by plants and other organisms.” Microplastics in the Environment As Beyond Pesticides has previously reported, microplastics are ubiquitous and threaten not only human health but all wildlife in both aquatic and terrestrial ecosystems. The universal distribution of plastics means that they cannot be avoided. Humans and other organisms take up plastics in the form of microparticles and nanoparticles by inhalation, ingestion, and skin contact every day. Microplastics are about the width of a human hair; nanoplastics […]

(Beyond Pesticides, February 24, 2025) The sweeping firing of federal workers, including an estimated 200,000 probationary employees (under one to two years of employment), will have a broad impact on programs to protect health and safety as well as the environment, leaving a critical need for local and state government to fill some of the gaps in critical programs, where possible. A headline in Science magazine warns, “Mass firings decimate U.S. science agencies,” and the dean of the College of Agricultural Sciences at Oregon State University told Oregon Public Broadcasting, “We’ve lost half of our teams, and all of these up-and-coming young scientists. . .so it’s like we’ve lost the next generation of scientists in agriculture and natural resources.” The same applies to important positions across the federal government, affecting every aspect of work necessary to protect public health and biodiversity and address the climate crisis. In response to President Trump’s executive orders and actions, there has been, as The New York Times reports, “new lawsuits and fresh rulings emerging day and night,” raising what experts fear may become a constitutional crisis. With the upheaval in the federal government, attention turns to the importance of state and local policies and […]

(Beyond Pesticides, January 2, 2025) Adding to the body of scientific literature on the fast escalating antibiotic resistance crisis is a study published by Chinese scientists in Environmental Science & Technology, which shows that antibiotic resistance genes (ARGs) in soils move up through trophic levels via predation. Gut microbiomes of soil fauna have been found to be reservoirs of ARGs. How this process operates in soils is vital, because what happens in soil microbes does not stay there. If bacteria altered in soils move up trophic levels, ARGs may strengthen the multicellular agricultural pests the industry is trying to kill—insects, fungi, plants—not to mention bringing their libraries of resistant genes into the microbiomes of vertebrates, including humans. Antibiotic resistance is a natural phenomenon, but human activity has greatly increased its presence in ecosystems the world over, including in one of the ecological niches of greatest concern to the future of food and human health: soils. Soils are complexes of mineral and organic substrates populated by billions of microorganisms and tiny animals. They are rapidly being degraded by conventional agriculture, forestry, and land management practices generally—more than a third of the world’s agricultural land has already been severely damaged by pesticides, […]

(Beyond Pesticides, November 25, 2024) When the U.S. Department of Agriculture (USDA) announced at the end of October a $15 million program to expand access to organic dairy products in schools, it added funds to an agency effort underway that is intended to support and incentivize farmers to grow organic and make organic food more widely available. While the millions being invested is a fraction of what organic advocates say is necessary, Congress and USDA have established a framework that recognizes the need to address the current health, biodiversity, and climate crises with accelerated adoption of organic. The issue now is whether organic will garner the support necessary to meet the life-sustaining challenges in the next Farm Bill, which may not be taken up until the next Congress is sworn in and the new administration is inaugurated. The U.S commitment to organic has been building since the adoption of the Agricultural Productivity Act in 1983, which established the Low Input Sustainable Agriculture program (later becoming the Sustainable Agriculture Research and Education (SARE) program) at USDA, and then the passage of the Organic Foods Production Act in 1990. However, among the articles published on the subject, research reported in Environmental Science & […]

(Beyond Pesticides, November 21, 2024) Be it Patagonia Provisions or Brooklyn Brewery, there is a buzz around organic beer that is increasingly evident given interest by brewing and food companies. The expansion of the organic beer market in the United States would not have been possible without the leadership of advocates, farmers, breweries, and the National Organic Standards Board (NOSB), which led to the strengthening of organic standards for beer back in 2010. The growth of this sector and transition to truly organic beer speaks to the spirit of “continuous improvement,” the original design of the Organic Foods Production Act (OFPA), and the importance of mobilizing the public to engage in the public input process that continues to keep organic law strong in opposition to those seeking an easier path to the organic label. Continuous Improvement and Organic Hops In the original drafting of OFPA, advocates came together to determine how to encourage the development of certified organic sectors despite the lack of available, verifiable organic inputs for many products—beer included. With this spirit in mind, the improvement of standards for beer encapsulates the significance of OFPA in the context of its flexibility, incentives, and the statutory intent to encourage […]

(Beyond Pesticides, October 28, 2024) STARTS WEDNESDAY—NATIONAL FORUM: IMPERATIVES FOR A SUSTAINABLE FUTURE. As scientific articles and regulatory reviews by the U.S. Environmental Protection Agency (EPA) focus on individual pesticides or families of pesticides and specific health outcomes associated with exposure, legislation introduced by U.S. Senator Cory Booker (D-NJ), S. 5084, Safe School Meals Act (SSMA), proposes a holistic response to the protection of children by banning pesticides in school lunches. While focused on the elimination of certain individual pesticides and other chemicals of known concern, the bill unilaterally allows children to be served food from certified organic farms. The overwhelmingly large body of scientific findings on the adverse effects of pesticides in the food that children eat in schools and generally. For example, last week Beyond Pesticides commented on EPA’s Draft Human Health and/or Ecological Risk Assessments for Several Pesticides, citing scientific findings that, “Neonicotinoids . . .have been found to affect mammalian nicotinic acetylcholine receptors (nAChRs) [which] are of critical importance to human brain function, especially during development and for memory, cognition, and behavior.” (See more here.) This month, Jennifer Sass, PhD, et al., in Frontiers in Toxicology, published a review of  unpublished rodent developmental neurotoxicity (DNT) studies […]

(Beyond Pesticides, October 24, 2024) When U.S. Senator Cory Booker (D-NJ) introduced S. 5084, Safe School Meals Act (SSMA) in September, he identified four objectives: Directing the Food and Drug Administration (FDA) to set safe limits for heavy metals in school meals. The limits will be based on a threshold of reasonable certainty of no harm to school-age children from aggregate exposure. If the agencies fail to set these limits within two years, the limits will automatically be set to non-detectable until the agencies can determine a safe level of exposure. Banning glyphosate, paraquat, and organophosphate pesticide residues in school meals. Certified organic farms would automatically meet this requirement. Banning PFAS, phthalates, lead, and bisphenols in food packaging in school meals. Directing FDA to reevaluate food additives with known carcinogenic, reproductive, or developmental health harms, such as artificial food dyes, and ban their use in school meals prior to the completion of FDA’s analysis. While groups like Beyond Pesticides applaud Senator Booker’s initiative to restrict exposure to some of the most hazardous toxicants, especially the most vulnerable subpopulation of children, their goal is to provide organic food to school children. In this spirit, groups have advocated that the U.S. Department […]

(Beyond Pesticides, October 7, 2024) American Academy of Pediatrics (AAP) released a newly revised technical report describing how antibiotic use in animal agriculture contributes to the development of antibiotic resistance in medical use and can adversely affect child health— in the context of this fast-emerging threat to U.S. and global health. This AAP finding comes just as the United Nations (UN) held its second High-Level Meeting on Antimicrobial Resistance (AMR) on September 26 (the first was held in 2016) at which global leaders committed “to a clear set of targets and actions, including reducing the estimated 4.95 million human deaths associated with bacterial antimicrobial resistance (AMR) annually by 10% by 2030.” The release from the UN, “World leaders commit to decisive action on antimicrobial resistance,” states, ”The Food and Agriculture Organization of the United Nations (FAO), the United Nations Environment Programme (UNEP), the World Health Organization (WHO) and the World Organisation for Animal Health (WOAH), known as the Quadripartite, welcome the declaration. The Quadripartite applauds countries for recognising the need for global, regional and national efforts to address AMR through a One Health approach, which recognizes that the health of people, animals, plants and the wider environment, including ecosystems, are closely […]

(Beyond Pesticides, October 3, 2024) The American Academy of Pediatrics published a technical report in September on antimicrobial resistance, which it calls a global public health threat, identifying the health implications of antibiotic use in animal agriculture. The lead authors, both medical doctors from the Department of Pediatrics at Vanderbilt University Medical Center, note the rise in antimicrobial-resistant infections that result in increased morbidity, mortality, and health care costs for not only adults, but infants and children as well. “[A]ll use of antimicrobial agents exerts selective pressure that increases the risk of development of resistance,” the authors state, highlighting the importance of limiting antimicrobial uses. “Antimicrobial resistance is an organism’s ability to survive exposure to an antimicrobial agent that was previously an effective treatment. Resistance traits can be acquired either through new mutations or through transfer of genetic material between organisms,” the authors report. Antimicrobial-resistant pathogens, such as bacteria and viruses, can be transmitted “through the food supply, direct contact with animals, environmental pathways, and contact with infected or colonized humans,” they continue. Use of antimicrobial agents, especially over extended periods of time or with repeated exposure, can cause resistance to not only that agent, but to multiple agents. As […]

(Beyond Pesticides, September 18, 2024) A literature review in Trends in Analytical Chemistry analyzes scientific articles from the last ten years from around the globe that identify more than 300 pesticides in bee pollen. Bee pollen, often used as an edible dietary supplement, is not regulated for pesticide residues, which sparks concern for human exposure due to contamination with pesticides, heavy metals, metalloids, and mycotoxins. “Bee pollen is a food supplement that is receiving increasing attention for its nutraceutical and therapeutic properties. However, several uncertainties on the safety of this beekeeping product still exist. The present work addressed this issue through the critical evaluation of 61 studies, published over the 2014–2024 period,” the Spanish authors state. Bee pollen is produced by honey bees. After they forage on flowers and gather pollen on their hind legs (in pollen baskets or corbiculae) to transport back to the hive, it is moistened with nectar and salivary secretions to create bee pollen in the form of pellets. While the composition of bee pollen can vary between geographical locations with different flowers, the studies reviewed all utilize mass spectrometry to pinpoint pesticides, as well as mycotoxins (created by naturally occurring mold spores), that threaten human […]

(Beyond Pesticides, September 17, 2024) Today, International Microorganism Day, is a prime moment to focus on the complexity of billions of living beings that establish the foundation of land management and food production. Organic advocates, community members, and farmers identify the protection and enhancement of biological diversity in the soil as a key goal, especially in light of mounting concerns over rising microbial resistance to chemical-intensive practices. A recent article in British Journal of Environmental Sciences points to several microbial populations adversely affected by pesticide-contaminated soil on various farmland plots in Nigeria. There are significant variations in bacteria presence between pesticide-treated and control plots, with a lab analysis finding “[s]eventy-five percent (75%) of pesticide residue was detected in the soil samples,” which includes paraquat dichloride, endosulfan, diazinon, and N-(phosponomethyl)glycine [glyphosate]. This report builds on years of research from higher education institutions worldwide, including participatory research centering applied experiments on farmland, demonstrating the consequences of relying on pesticide-intensive agriculture and land management. The main goal of this report is to “determine the influence of pesticide contamination on the microbial population, physiochemical parameters and pesticide residue of soil of selected farmlands in Otuoke, Bayelsa State, Nigeria.” Researchers document the presence of eleven […]

(Beyond Pesticides, September 12, 2024) In a year with 74 national elections on the calendar, legislators and executive branches alike are in contention on the future of business-as-usual pesticide use and manufacturing. Be it Kenya or Brazil, the European Union and Mercosur (South American Trade Bloc), there is a growing contingency of farmers, advocates, researchers, and public leaders who desire a pathway forward in strengthening pesticide restrictions and supporting alternatives to chemical-intensive agriculture and land management, including organic. As leadership shifts and domestic conversations mount ahead of the 2024 United Nations Climate Change Conference (COP29) in Azerbaijan and the 2024 National Organic Standards Board meeting this fall, environmental and health advocates say it is vital that world leaders acknowledge the decades of grassroots advocacy and market development that led to the growth of organic systems in service of building capacity for nutrition, public health, biodiversity, and climate resilience while advancing food security. Kenya Earlier this month, the Kenyan parliament introduced a resolution to ban hazardous pesticides including glyphosate-based herbicide products such as RoundUp sold by Bayer/Monsanto, leading to a fiery debate on the state of agricultural uses. Hon. Gladys Boss, Deputy Speaker for the National Assembly, speaks to the rationale […]

(Beyond Pesticides, September 4, 2024) A study in the Journal of Environmental Science and Public Health adds to the body of science that highlights the ecological decline threatening all species as a result of hazardous chemicals in the environment. “When environmental changes undermine a species’ or population’s ability to survive, it is said to be in an ecological crisis,” the authors state. They continue, “Pesticides, particularly persistent organic pollutants (POPs), are among the top ten chemicals and hazardous compounds that the WHO [World Health Organization] has recognized as being a concern for global health. The overuse and improper handling of agrochemicals is the primary driver of the ecological disaster.”   The researchers, from the Post Graduate Institute of Medical Education and Research in India, conducted a literature review to look broadly and comprehensively at the range of factors that contribute to adverse health effects (from breast cancer to genotoxic effects, chronic kidney disease, neurotoxicity, and more). They searched PubMed and Google Scholar for studies between 2004-2024 for relevant information on soil health, sustainable agriculture, food security, soil security, and the associations with human health. Their scientific findings lead the authors to conclude that the building of healthy soils will eliminate the need […]

(Beyond Pesticides, August 21, 2024) A literature review, published this month in the Journal of Agricultural and Food Chemistry, explores levels of pesticide residues found in samples of human urine with environmental exposure and dietary intake and confirms prior findings about the benefits of an organic diet. Similar to past findings, lower concentrations of chemicals are detected in the urine of participants who report eating an organic diet. By analyzing 72 scientific research studies published between 2001 to 2023, the review assesses routes of exposure and “explores urinary concentrations and detection frequency of metabolites of organophosphates and pyrethroids, as well as herbicides such as 2,4-D and glyphosate,” the authors say. While “exposure to pesticide residues is influenced by a variety of demographic factors, including occupation, agricultural practices, seasonal variations, residence, diet, age, and gender,” the authors say, the concentrations of pesticides and their metabolites in human urine highlights the disproportionate risk to certain groups as well as the overall threat to the health of humans and the environment. Pesticide exposure can occur from dermal/skin contact or inhalation, through residence or work, and with dietary intake. “Pesticides in urine can be detected as parent compounds, specific metabolites corresponding to a specific […]

(Beyond Pesticides, July 15, 2024) It is hot. Really hot. A serious response to this climate emergency requires, according to environmental advocates, a dramatic transformation in land management and an end to the use of petrochemical pesticides and fertilizers. Beyond the real-world adverse effects of the climate crisis— more intense and frequent fires, floods, hurricanes and hail storms, as well as the harm to health and biodiversity—the rising insurance premiums imposed by the insurance industry speaks to the need for an urgent systemic response. According to the paper, Pricing of Climate Risk Insurance: Regulation and Cross-Subsidies, “The unprecedented rise in natural disasters has led to catastrophic losses of more than $600 billion in the United States over the last two decades, roughly twice the losses of the previous 40 years combined.” While the events associated with climate are more accurately described as “human-made” rather than “natural” disasters, a 2023 Washington Post article reports that, “U.S. insurers have paid out $295.8 billion in natural disaster losses from 2020 to 2022, a record for a three-year period.” This has led to dramatic changes in the cost of insurance coverage and the decision of many carriers to deny coverage. The Washington Post writes, “At least […]

(Beyond Pesticides, July 28, 2024) Most people don’t like bugs, but the fact is that insects form the foundation of human flourishing, both for their ecosystems services, like pollination of food crops, and for their aesthetic joys. But insect populations globally are declining two to four percent a year, with total losses over 20 years of 30-50 percent, according to a new study of the interacting effects of pesticides, climate, and land use changes on insects’ status in the Midwest. Teasing out the relative influence of these stressors has been a major obstacle in determining the causes of the declines and ways to mitigate them. The icon of insect beauty in the U.S. is the monarch butterfly, whose vibrant coloring, elegant form, and spectacular migrations inspire everyone. Beyond Pesticides has covered the distressing decline of these creatures, most recently in the June 24 Daily News. Monarchs prefer milkweed plants, but also visit many other flowers. Milkweed often grows along the margins of fields, so monarchs are widely exposed to pesticides and habitat disturbances associated with agriculture. The new study was published in PLoS One by a team of scientists from the Washington Department of Fish and Wildlife, Michigan State University, […]

(Beyond Pesticides, June 27, 2024) Earlier this month, Public Employees for Environmental Responsibility (PEER) filed a lawsuit against the U.S. Environmental Protection Agency (EPA) on behalf of a group of ranchers and farmers in Texas harmed by biosolids contaminated with per- and polyfluoroalkyl substances (PFAS). The plaintiffs charge that their health and livelihoods were severely damaged due to contaminated biosolids leaching from neighboring properties onto their land. Despite EPA’s responsibility under the Clean Water Act (Section 405(d) and 40 CFR Part 503) to identify toxic pollutants in biosolids and regulate them to protect human health and the environment, the agency has not effectively addressed the dangers posed by PFAS in biosolid fertilizers. EPA’s failure has dramatic impacts on farmers as well as the public, who are eating or drinking PFAS-contaminated crops, dairy milk, beef, or other meat products. The shortcomings of federal regulations underscore the urgent need for a shift in how federal and state agencies approach these issues, prioritizing precaution to prevent future harm. The persistence of these legacy or “forever” chemicals in the environment illustrates the severe consequences of a historically lax regulatory framework in the U.S.  The National Association of State Departments of Agriculture (NASDA) has identified […]

(Beyond Pesticides, May 29, 2024) A study from the Academy of Biology and Biotechnologies and the Federal Rostov Agricultural Research Centre adds to the body of science linking pesticide use with negative impacts on soil health and bacterial communities. Antibiotic-resistance genes (ARGs), considered a class of pollutants, are found in certain types of bacteria and can spread through the environment and subsequently to humans and animals. This study, performed by researchers and soil experts, found an increase in specific bacterial families that host ARGs with exposure to pesticides.  The study aims to identify the role of agricultural soils in ARG transfer and to assess the presence and prevalence of bacterial families with and without exposure to fertilizers and pesticides. Since soil serves as a habitat for a wide range of bacteria, including many that are resistant to antibiotics, analyzing the organisms within soil samples is an indicator of overall environmental health. Agricultural soils are essential in food production, and as this study states, “[I]ntensive exploitation of such soils implies the widespread use of various chemical plant protection products (insecticides, herbicides, fungicides) and mineral fertilizers, which contribute to pollution and a decrease in soil quality.”   Within this field study, there is […]

(Beyond Pesticides, May 28, 2024) Public comments are due May 29, 2024. With 40 percent of all vegetables grown in the U.S. coming from the state of California, the current state level process to define “regenerative agriculture” could have major impact on land management practices that address the current climate, biodiversity, and health crises. That is, according to advocates, if the process, directed by the California Department of Food and Agriculture (CDFA) departs from a history of poorly defined and unenforceable terms like Integrated Pest Management (IPM) and Sustainable Agriculture. Virtually all consumers of food have a stake in the outcome of the definition of “regenerative,” so the current public comment period, which closes tomorrow, May 29, 2024, can help influence the outcome. As Beyond Pesticides has reported previously, the term “regenerative” is now increasingly being advanced as a loosely defined alternative to the organic standard and label, which is transparent, defined, certified, enforced, and subject to public input. The  publication AgFunderNews (AFN) in February published its updated “2024 list of agrifood corporates making regenerative agriculture commitments,” a who’s who of the largest food and agribusiness corporations worldwide. The list includes companies such as ADM, Cargill, Danone, General Mills, Tyson, Unilever, Walmart, and more with commitments […]