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New Viewpoint on the Historic Link between Endocrine Disrupting Chemicals and Cancer Discussed

Thursday, May 25th, 2023

(Beyond Pesticides, May 25, 2023) A review of scientific literature published in the Journal of Endocrinological Investigation demonstrates exposure to past and current-use endocrine-disrupting chemicals (EDCs), like pesticides, have a long history of severe adverse human health effects. Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem) present in nearly all organisms and ecosystems. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Endocrine disruption can lead to several health problems, including hormone-related cancer development (e.g., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Therefore, studies related to pesticides and endocrine disruption help scientists understand the underlying mechanisms that indirectly or directly cause infertility, among other health issues. The review notes, “New evidence supports the role of other EDCs as possibly carcinogenic and pregnant women should avoid risk area and exposure. The relationship between EDCs and cancer supports the need for effective prevention policies increasing public awareness.” The review examines the relationship between EDCs and various hormone-mediated various (i.e., breast, prostate, testicle, ovary, and thyroid) to determine the carcinogenicity of the chemicals and their impact on public […]

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Research Further Associates Widespread Atrazine Exposure to Breast Cancer

Thursday, March 30th, 2023

(Beyond Pesticides, March 30, 2023) A study published in Ecotoxicology and Environmental Safety finds that the commonly used herbicide, atrazine, promotes breast cancer development through suppression of immune cell stimulation, and thus function, and upregulation of enzymes mediating tumor development. According to the Centers for Disease Control and Prevention (CDC), breast cancer is a disease that causes breast cells to grow out of control, with the type of breast cancer depending on the cells themselves. Several studies and reports, including U.S. Environmental Protection Agency (EPA) data, identify hundreds of chemicals as influential factors associated with breast cancer risk. Breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. Past studies suggest genetic inheritance factors influence breast cancer occurrence. However, genetic factors only play a minor role in the incidence of breast cancer, while exposure to external environmental factors (i.e., chemical exposure) appears to play a more notable role. One in ten women will receive a breast cancer diagnosis, and genetics can only account for five to ten percent of cases. There are grave concerns over exposure to endocrine (hormone) disrupting chemicals and pollutants that cause adverse health effects. Therefore, advocates point to the need for national […]

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Legal Case Opens To Stop Antibiotics in Citrus and Advance Organic, Given Resistant Bacteria Crisis

Tuesday, January 24th, 2023

(Beyond Pesticides, January 24, 2023) Oral arguments begin this week in a lawsuit challenging the U.S. Environmental Protection Agency’s (EPA) approval of the antibiotic streptomycin as a pesticide on citrus crops. Brought forth by a coalition of farmworker, health, and environmental groups, the lawsuit aims to stop the use of a critical medical treatment for agricultural purposes. “Humanity’s dwindling supply of medically effective antibiotics is not worth sacrificing for an industry that has safer alternatives available,” said Drew Toher, community resource and policy director at Beyond Pesticides. “Despite the challenges, we know from the elimination of this material in organic production that we don’t need antibiotics in order to produce a glass of orange juice.”  In 2020, the Lancet published an article that identifies several of the multiple and interacting crises the U.S. and world face, with a focus on another “looming potential pandemic . . . [a] rise in multidrug-resistant bacterial infections that are undetected, undiagnosed, and increasingly untreatable, [whose rise] threatens the health of people in the USA and globally.” It calls on leaders in the U.S. and beyond, asking that even as they address the current coronavirus pandemic, they also attend to the antimicrobial resistance (AMR) problem, […]

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Neonicotinoid Insecticides Adversely Affect Nervous System Health, According to Study

Thursday, January 19th, 2023

(Beyond Pesticides, January 19, 2023) Research published in Environmental Health Perspectives finds the presence of nine various neonicotinoids (neonics) and six neonic metabolites within human cerebrospinal fluid (CSF). CSF is an essential part of the central nervous system (CNS), especially for CNS development. Specific chemical biomarkers (measurable indicators of biological state), like pesticides, found in CSF are useful for diagnosing and evaluating numerous neurological diseases. The nervous system is an integral part of the human body and includes the brain, spinal cord, a vast network of nerves and neurons, all of which are responsible for many of our bodily functions—from sensed to movement. However, mounting evidence over the past years shows that chronic exposure to sublethal (low) levels of pesticides can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. The impacts of pesticides on the nervous system, including the brain, are hazardous, especially for chronically exposed individuals (e.g., farmworkers) or during critical windows of vulnerability and development (e.g., childhood, pregnancy). Researchers identify the role agricultural chemicals play in CNS impacts causing neurological diseases, like amyotrophic lateral sclerosis (ALS) and Parkinson’s disease, dementia-like diseases such as Alzheimer’s, and other effects on cognitive function. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood […]

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Glyphosate Weed Killer Crosses Blood-Brain Barrier, Linked to Alzheimer’s and Other Neurodegenerative Diseases

Thursday, August 4th, 2022

(Beyond Pesticides, August 4, 2022) An Arizona State University (ASU) study shows that the popular herbicide glyphosate can infiltrate the brain through the blood (blood-brain barrier), increasing neurological disease risk. The blood-brain barrier filters various molecules entering the brain from the circulatory system. However, the permeation of glyphosate molecules elevates the expression of TNFÎą and the accumulation of soluble beta-amyloid (Aβ) proteins in the brain and has associations with immune, inflammatory, and neurodegenerative diseases like Alzheimer’s disease (AD). More than 6 million people in the U.S. are living with Alzheimer’s, and cases are expected to double by 2050. Although Alzheimer’s research has focused heavily on finding genetic causes of the disease, fewer than half of cases are genetic. Thus, researchers are now evaluating how environmental contaminants may increase disease risk. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood and urine samples and can increase neurotoxicity risk when crossing the brain barrier. Therefore, studies like this highlight the importance of understanding how chemical accumulation in the body can impact long-term health and disease prognosis. The study notes, “Brain glyphosate correlates with increased TNFÎą levels, suggesting that exposure to this herbicide may trigger neuroinflammation in the brain, which may […]

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Common Fungicide Again Linked to Parkinson’s Disease with Molecular Disruption

Thursday, June 30th, 2022

(Beyond Pesticides, June 30, 2022) A study by Zhongnan University and Shandong University in China finds that the broad-spectrum fungicide maneb increases Parkinson’s disease (PD) risk and development through alterations in protein and metabolite pathways, resulting in neurotoxicity. Several studies find exposure to chemical toxicants, like pesticides, have neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, this study suggests neurological damage from oxidative stress, cell dysfunction, and synapses impairment, among others, increases the incidence of PD subsequent to pesticide exposure. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While only 10 to 15 percent of PD cases are genetic, PD is quickly becoming the world’s fastest-growing brain disease. Therefore, research like this highlights the need to examine molecular mechanisms involved in altering chemical […]

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Breakthrough Study Shows Organophosphate Nerve Gas Caused Gulf War Illness

Tuesday, May 24th, 2022

(Beyond Pesticides, May 24, 2022) New research is providing strong causal evidence that Gulf War Illness (GWI) is the result of exposure to sarin gas, an organophosphate nerve agent used by Saddam Hussein as a chemical weapon during the Gulf War. The findings, published earlier this month in Environmental Health Perspectives, have important implications for the hundreds of thousands of American service members suffering from a constellation of chronic symptoms without a true understanding of how they became sick. “Quite simply, our findings prove that Gulf War illness was caused by sarin, which was released when we bombed Iraqi chemical weapons storage and production facilities,” said Robert Haley, MD, lead author of the study and epidemiologist at University of Texas Southwestern. “There are still more than 100,000 Gulf War veterans who are not getting help for this illness and our hope is that these findings will accelerate the search for better treatment.” Sarin was first synthesized in the late 1930s by Nazi chemists working for IG Farben (a consortium that included Bayer) in an attempt to create stronger and more powerful insecticides. Sarin is a G-series organophosphate (named after the scientists that created them), characterized by high acute toxicity and […]

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Pesticides and Parkinson’s Disease: The Toxic Effects of Pesticides on the Brain

Thursday, December 16th, 2021

(Beyond Pesticides, December 16, 2021) A study by Shanghai Jiao Tong University, China, finds Parkinson’s Disease (PD) risk increases with elevated levels of organochlorine (OCP) and organophosphate (OP) pesticides in blood. Among patients with PD, specific organochlorine compounds have greater associations with cognitive impairments, including depression and brain function. Research finds exposure to chemical toxicants, like pesticides, can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, researchers suggest changes in protein enzyme composition and cellular dysfunction from pesticide exposure interrupt normal brain function. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses each year. The disease affects 50% more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While only 10 to 15 percent of PD incidences are genetic, PD is quickly becoming the world’s fastest-growing brain disease. Therefore, research like this highlights the need to examine alternate […]

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Degenerative Lung Diseases Associated with Atrazine Exposure, Worsened in Combination with Common Cancer Treatment

Friday, December 3rd, 2021

(Beyond Pesticides, December 2, 2021) A study published in Cellular Physiology and Biochemistry finds atrazine (ATR) exposure worsens lung disease outcomes in individuals with idiopathic (spontaneous) pulmonary fibrosis (IPF), a group of incurable lung diseases involving damaged/scarred lung tissue. Furthermore, chemotherapeutic products used to treat lymphoma (immune system cell cancer) like bleomycin can induce pulmonary fibrosis complications exacerbated by pesticide exposure. However, pesticide-related pulmonary fibrosis can have implications for neurological health, such as motor function. Scientific literature already finds an association between pesticide exposure and respiratory illnesses such as asthma, lung cancer, and chronic obstructive pulmonary disease (chronic bronchitis). Although IPF impacts over 5 million people a year globally, the disease is difficult to predict, which is concerning as the death rate is 50 to 56 percent within the first few years. Therefore, studies like this highlight the significance of evaluating how pesticide exposure impacts respiratory function, especially when exposure to respiratory toxicants increases vulnerability to existing respiratory-fixated illnesses like Covid-19. Advocate have urged the U.S. Environmental Protection (EPA) to incorporate scientific findings that these—where chemical exposures exacerbate an existing medical condition—into its pesticide registration review program. Researchers note, “[O]ur data represent an addition to the complex information on ATR-induced pulmonary toxicity. In particular, in this […]

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Endocrine (Hormone) Disrupting Chemicals, Including Pesticides, Also Affect the Nervous System

Thursday, September 9th, 2021

(Beyond Pesticides, September 9, 2021) A new study published in Toxicology Reports finds the same chemicals that disrupt the endocrine (hormone) system also disrupt the nervous system. Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem) present in nearly all organisms and ecosystems. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Past research shows exposure to endocrine-disrupting pesticides adversely affects human health, from reproductive function to cancer development, and effects can span generations. However, this study is one of the few to evaluate associations between endocrine-disrupting chemicals and neurological function. Although the etiology (cause) of many sporadic (non-heritable) neurological diseases are unknown, scientists suggest exposure to environmental toxicants plays a role in disease development. Therefore, government and health officials have been urged to consider how exposure to endocrine-disrupting chemicals can impact bodily function and development apart from hormone disruption.   In the body, cells communicate through electrical or chemical signals transmitted within the nervous or endocrine system. Studies find exposure to endocrine-disrupting chemicals has a direct and indirect impact on hormone function and development. However, researchers investigated whether […]

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Breakdown Products (Metabolites) from Pesticides May Be More Toxic than Parent Compound, Study Finds

Thursday, May 6th, 2021

(Beyond Pesticides, May 6, 2021) Nearly half of all breakdown products (transformation products) from four common-use environmental pesticides produce stronger endocrine (hormone) disrupting (ED) effects than the parent compound, according to new research published in Environment International. Over 300 environmental contaminants and their byproducts—from chemicals in plastics to cosmetic/personal care products—are commonly present in water bodies, food commodities, and human blood/urine samples. These toxicants can alter hormone metabolism, producing endocrine-disrupting effects that put the health of animals, humans, and the environment at risk. Many ecological and health risk assessments for pesticides focus on the effects of parent chemical compound products, overlooking the potential impacts of transformation products (TPs). Therefore, studies like these highlight the need to assess the implications of TPs to safeguard human, animal, and environmental health. The researchers note, “Since an increasing number of pesticide TPs have been detected in various environmental media, a more comprehensive understanding of the ecological risk of pesticide TPs is imperative for risk assessments more extensively and regulatory policy-making on pesticide restriction in the future.” Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem), including pesticides, bisphenols, phthalates, persistent organic pollutants (POPs), and heavy metals. Past research demonstrates exposure […]

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EPA Confirms Widespread PFAS Contamination of Pesticides, Announces “Investigation,” Stops Short of Action to Protect Public

Wednesday, January 20th, 2021

(Beyond Pesticides, January 20, 2021) The U.S. Environmental Protection Agency has confirmed that PFAS (per and polyfluorinated alykyl substances) ‘forever chemicals’ are contaminating containers that store pesticide products, and subsequently the products themselves. The confirmation comes after preliminary testing from the watchdog group Public Employees for Environmental Responsibility (PEER) found PFAS in the widely used mosquito pesticide Anvil 10+10. In response EPA announced further investigation and said, “EPA understands the need to provide guidance to states, tribes, and other users as they prepare to purchase mosquito control products for 2021 and will provide more information as it continues its investigation. EPA will update the following webpage with information as it becomes available: https://www.epa.gov/pesticides/pfas-packaging.” “EPA’s discovery has opened a Pandora’s Box of health risks,” stated PEER Science Policy Director Kyla Bennett, PhD, whose testing of the insecticide first raised the alarms, according to the EPA statement.  “Shipping containers may be a significant source of PFAS exposure through the entire U.S. agricultural sector.” According to EPA, high-density polyethylene (HDPE) containers used to store and transport pesticides are commonly treated with fluoride in order to create a “chemical barrier” that will “prevent changes in chemical composition.” The fluorinated container is supposed to be more stable, […]

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Defense Spending Bill Set to Expand Coverage for Veterans Harmed by Agent Orange

Wednesday, December 16th, 2020

(Beyond Pesticides, December 16, 2020) Part of U.S. Senator Jon Tester’s (D-MT) Fair Care for Vietnam Veterans Act is set to be included in the federal defense spending bill, providing hope that service members continuing to suffer from diseases related to Agent Orange exposure will receive long needed health coverage. The amendment to the National Defense Authorization Act (NDAA) received bipartisan support, and NDAA is expected to pass through both houses of Congress with a veto-proof majority. Nonetheless, President Trump has threatened a veto. “…I fought tirelessly for years alongside our friends over at [Veterans of Foreign Wars] and other veteran service organizations,” Senator Tester said during a recent press conference, per the Missoula Current. “And I’m proud to have waged this fight. Now, Vietnam veterans suffering from diseases associated with exposure to Agent Orange are on the cusp to receive critical care and benefits that they’ve earned.” The issue at hand is whether four Agent Orange-related diseases – Parkinsonism, bladder cancer, hypertension, and hypothyroidism, should be considered eligible for benefits and disability compensation by the Department of Veteran’s Affairs (the VA). According to the veteran advocacy group DAV, 83,000 former servicemembers suffer from these diseases. While the scientific literature […]

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PFAS ‘Forever Chemicals’ Found in Mosquito Pesticide, Raising Concerns Over Widespread Contamination

Wednesday, December 2nd, 2020

(Beyond Pesticides, December 2, 2020) PFAS (per and polyfluorinated alykyl substances) ‘forever chemicals’ are being detected in a commonly used mosquito pesticide known as Anvil 10+10, according to reporting from the Boston Globe based on independent testing from a watchdog group and state regulators. PFAS are a large family of nearly 5,000 chemicals that may never break down in the environment and have been linked to cancer, liver damage, birth and developmental problems, reduced fertility, and asthma. The chemicals already disproportionately contaminate people of color communities, and there is evidence they reduce the efficacy of vaccines. While many may be familiar with PFAS for its use in nonstick cookware, electrical wire insulation, personal care products, food packaging, textiles, and other consumer goods, its presence within an already toxic pesticide is alarming. Perhaps most concerning, neither the manufacturer nor regulators have a good understanding of how exactly PFAS chemicals made their way into pesticide products. “This is an issue that cuts to the core of what’s wrong with our federal system for regulating pesticides,” said Drew Toher, community resource and policy director at Beyond Pesticides. “The finding makes it imperative that EPA review and disclose full pesticide formulations before allowing the […]

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Work-Related Exposure to Pollutants Increases the Risk of Developing Heart Defects in among Hispanic/Latinx Communities

Thursday, September 3rd, 2020

(Beyond Pesticides, September 3, 2020) Occupational exposure to pollutants including, those from wood burning, pesticides, metals, and vehicle combustion, increases the risk of developing heart abnormalities among Latinx individuals, according to new research published in the Journal of the American Heart Association. Although previous research focuses on the impact of pollutants on human health from occupational or residential exposure, this study highlights the risk chemical exposure can have on communities, especially for those underrepresented in conventional occupational health studies, such as those with Hispanic or Latinx backgrounds. People of color communities are already at greater risk of exposure to environmental and health harms, such as pesticide pollution, which has been identified as environmental racism. Additionally, not only are people of color at risk of developing various, serious health issues associated with additional or cumulative pesticide exposure, they disproportionately face an elevated risk from Covid-19 as essential workers or family members of those workers. According to the researchers, “The objective of this study was to assess the relationship between occupational exposure to hazardous substances and cardiac structure and function in Hispanic/Latino participants in ECHO‐SOL (Echocardiographic Study of Latinos).” It is significant as it highlights the regular/routine exposure to environmental pollutants, including pollution from […]

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Court Decision Highlights Systemic Failure of Federal Pesticide Law to Protect Health and the Environment, Despite a Silver Lining and a Must-Read, Powerful Dissenting Opinion

Tuesday, August 11th, 2020

(Beyond Pesticides, August 11, 2020) Petitioners who mounted a legal challenge to the Environmental Protection Agency’s (EPA’s) registration of Enlist Duo, a relatively new and highly toxic pesticide product, recently learned of a mixed decision from the U.S. Ninth Circuit Court of Appeals in the case. The good news is that Judge Ryan D. Nelson, writing the opinion for the court, found that EPA, in registering the herbicide Enlist Duo, had failed to protect monarch butterflies, which are under consideration as a threatened species under the Endangered Species Act (ESA). On the other and disturbing hand, the court concluded that EPA registration of the product was otherwise lawful — which means that this toxic compound will for now remain on the market. As one of the plaintiffs in the case, Beyond Pesticides is adamant that this product should not be registered for use by EPA. George Kimbrell, Legal Director of Center for Food Safety and Lead Counsel for the plaintiffs, commented on the decision in the organization’s July 22 press release on the decision: “The panel majority’s unprecedented decision is contrary to controlling law and established science, and Center for Food Safety is analyzing all legal options, including seeking a full […]

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Insist that the Veterans Administration Cover Conditions Caused by Agent Orange

Monday, January 27th, 2020

(Beyond Pesticides, January 27, 2019) United States military veterans suffering from bladder cancer, hypothyroidism, hypertension, and Parkinson’s-like symptoms after their exposure to Agent Orange will remain unprotected and uncompensated until at least late 2020, according to a letter sent by Veterans Affairs (VA) Secretary Robert Wilkie to U.S. Senator Jon Tester (D-MT). Send a letter to Veterans Affairs (VA) Secretary Robert Wilkie insisting that bladder cancer, hypothyroidism, hypertension, and Parkinson’s-like symptoms be added to the VA’s list of eligible conditions. Congress included a provision in the must-pass December federal spending bill requiring VA to provide legislators “a detailed explanation” for the now multi-year delay in determining whether to list the diseases. The provision is intended to cut through the ongoing delays, but there is no indication VA is going to meet the 30-day deadline. “The longer VA continues to drag its feet on expanding the list of conditions associated with Agent Orange, the longer our veterans continue to suffer—and die—as a result of their exposure,” Senator Tester said in a statement to the news site Connecting Vets. He continued, “It’s time for VA to stop ignoring the overwhelming evidence put forth by scientists, medical experts and veterans and do right by those who served. Any prolonging of […]

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At a Time of Precarious Military Actions, Trump Administration Delays Benefits to Agent Orange Veterans

Thursday, January 9th, 2020

(Beyond Pesticides, January 9, 2020) United States military veterans suffering from bladder cancer, hypothyroidism, hypertension and Parkinson’s-like symptoms after their exposure to Agent Orange will remain unprotected and uncompensated until at least late 2020, a letter sent by Veterans Affairs (VA) Secretary Robert Wilkie to U.S. Senator Jon Tester (D-MT) indicates. Congress included a provision in the must-pass December federal spending bill requiring VA to provide legislators “a detailed explanation” for the now multi-year delay in determining whether to list the diseases. This is seen by advocates for veterans as a serious lack of support and compensation just at a time when the current administration mobilizes the military. According to Military Times, 83,000 veterans suffer from bladder cancer, Parkinson’s-like symptoms or hypothyroidism, and an untold number have high blood pressure. The paper interviewed Army Sgt. Maj. John Mennitto, who explained, “Since we first spoke in 2016, I have been diagnosed with bladder cancer. . . I also have hypothyroidism. My greatest concern for me and my fellow veterans who have debilitating diseases caused by exposure to Agent Orange is that our family members will be left with nothing.” A robust 2014 review by the National Academy of Medicine recommended including […]

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Deadly Dioxin, An Agent Orange By-Product, Continues to Contaminate Vietnam

Tuesday, March 12th, 2019

(Beyond Pesticides, March 12, 2019) Fifty years after the end of the Vietnam War, the Agent Orange byproduct dioxin continues to contaminate Vietnam’s soils and wildlife, and subsequently affect human health. In their review, scientists at Iowa State and the University of Illinois focus on the locations where hot spots and contaminated sediments have persisted after 130,000 fifty-five gallons drums of toxic herbicides were sprayed over Vietnam’s farm fields and jungle canopies during the war. “Existing Agent Orange and dioxin research is primarily medical in nature, focusing on the details of human exposure primarily through skin contact and long-term health effects on U.S. soldiers,” says Ken Olson, PhD, co-author on the article. “In this paper, we examine the short and long-term environmental effects on the Vietnamese natural resource base and how persistence of dioxin continues to affect soils, water, sediment, fish, aquatic species, the food supply, and Vietnamese health.” While public attention has generally focused on the “rainbow herbicides,” such as Agent Orange, used during the Vietnam war, it is the dioxin TCDD (2,3,7,8 tetrachlorodibenzodioxin), a byproduct of Agent Orange’s manufacturing process, that has caused the most lasting damage within the country. While the breakdown period for Agent Orange herbicides 2,4-D […]

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Evaluation Used to Support Registration of Neurotoxic Chlorpyrifos Found To Be Fundamentally Flawed

Tuesday, November 20th, 2018

(Beyond Pesticides, November 20, 2018) Scientific conclusions used to support the registration of the insecticide chlorpyrifos were flawed and omitted key health impacts, according to a fresh analysis of the original data by a team of independent scientists from northern Europe and the U.S. This re-review not only casts further doubt on the safety of the neurotoxic chlorpyrifos, it highlights a major flaw within federal pesticide regulation that allows pesticide producers to submit their own safety evaluations to the U.S. Environmental Protection Agency without public oversight. “One conclusion we draw is that there is a risk that the results of industry-funded toxicity tests are not reported correctly,” says co-author Axel Mie, PhD. “This makes it difficult for the authorities to evaluate the pesticides in a safe and valid way.” In both the U.S. and European Union, pesticide producers contract with laboratories to perform required safety tests of active ingredients they hope to register for use. While these studies are generally considered ‘confidential business information’ and not available to the public, using Swedish freedom of information laws, researchers were able to obtain two key studies relating to the developmental neurotoxicity of chlorpyrifos. Although not disclosed within the study, it is well […]

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Military Base Has Legacy of Pesticide and Other Toxic Chemical Exposure and Harm

Wednesday, September 19th, 2018

(Beyond Pesticides, September 19, 2018) “‘Don’t get pregnant at George Air Force Base’” was the advice imparted from one female Air Force member to another in 1975 at that base, located 100+ miles north of San Diego and used as an active military site from 1941–1992. From the start of their service at George AFB, both parties to this conversation came to be familiar with the shared horror stories of repeated infections, vaginal bleeding, ovarian cysts, uterine tumors, birth defects, and miscarriages among female Air Force members at the site. Many women who served at George AFB in the 1970s, ‘80s, and ‘90s suffered, but did not know what was causing, such health issues, which were frequent enough that even base doctors would sometimes privately warn women off of getting pregnant while serving there. Among the many contaminants found at George AFB and other military sites are organochlorine-based pesticides (OCPs), such as DDT, dieldrin/aldrin, heptachlor, lindane, endrin, chlordane, mirex, toxaphene, hexachlorobenzene, chlordane, and others. (A comprehensive list of OCPs is available here.) Most of these compounds were used on military bases for decades for vegetation control, as building pesticides or fumigants, or for personal pesticide treatments for lice and scabies, and […]

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Vietnam Demands Compensation from Monsanto for Devastating Harm Caused by Agent Orange During War

Tuesday, September 4th, 2018

(Beyond Pesticides, September 4, 2018) Close on the heels of the recent landmark California decision against Monsanto, maker of the glyphosate-based pesticide Roundup, Vietnam has demanded that the company pay damages to the many victims of its Agent Orange herbicide and defoliant, which Monsanto supplied to the U.S. military during the Vietnam War. (Monsanto was not the only U.S. manufacturer of the compound; there were nine in total.) U.S. forces, in a program dubbed Operation Ranch Hand, used more than 13 million gallons of the compound in Vietnam — nearly one-third of the 20 million gallons of all herbicides used during the war in Laos, Cambodia, and Vietnam. In Vietnam alone, 4.5 million acres were impacted by Agent Orange. Nguyen Phuong Tra, a spokesperson for Vietnam’s foreign ministry, said, “The [U.S.] verdict serves as a legal precedent which refutes previous claims that the herbicides made by Monsanto and other chemical corporations in the U.S. and provided for the U.S. army in the war are harmless. . . . Vietnam has suffered tremendous consequences from the war, especially with regard to the lasting and devastating effects of toxic chemicals, including Agent Orange.” Around the world, the U.S. case may be sparking […]

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U.S. Court Tells EPA to Ban Chlorpyrifos

Friday, August 10th, 2018

(Beyond Pesticides, August 10, 2018) The U.S. Environmental Protection Agency (EPA) must ban a widely used organophosphate pesticide linked to brain damage in children, the 9th Circuit Court of Appeals ruled yesterday. The appellate court ordered EPA to finalize its proposed ban on chlorpyrifos, produced by DowDupont, based on undisputed findings that the pesticide is unsafe for public health, and particularly harmful to children and farmworkers. The ruling comes in a lawsuit brought by a coalition of labor and health organizations, represented by Earthjustice. In the absence of EPA action, states have started to stand up. In May, the state legislature in  Hawaii passed legislation, which took effect in May, to become the first state to ban the chemical. On July 30, the California Department of Pesticide Regulation (DPR) released its scientific assessment concluding that the organophosphate insecticide, chlorpyrifos, should be listed as a Toxic Air Contaminant (TAC) in the state based on evidence of its neurological effects and exposure risks of concern. Legislation is also pending in Congress to ban chlorpyrifos and similar pesticides nationwide. Chlorpyrifos is a dangerous nerve agent pesticide that can damage the developing brains of children. Prenatal and early life exposure to chlorpyrifos is linked to lower birth weight […]

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