(Beyond Pesticides, November 14, 2025) A literature review in Ecotoxicology and Environmental Safety finds a sex-specific relationship between pesticide exposure and thyroid cancer, with heightened risks for women. “Thyroid cancer (TC) is one of the most common endocrine malignancies worldwide, yet the association between pesticide exposure and TC has not been systematically summarized,” the authors state. “This study aimed to elucidate the relationship between pesticide exposure and TC, focusing on insecticides, herbicides, and fungicides.” In the U.S., approximately 44,020 new cases and 2,290 deaths are estimated for 2025, according to the American Cancer Society, with thyroid cancer as the ninth most common cancer in women. (See research here.) TC ranks globally as the tenth most common cancer, representing a worldwide threat to both men and women. (See here.) The current study considers scientific literature on thyroid cancer and pesticide exposure by pesticide type to extract data and statistically analyze the link between exposure and risk of TC. The results indicate a positive association between exposure to insecticides, herbicides, and fungicides and thyroid cancer, with the sex-based analysis revealing the risk of TC is higher in females. Study Background and Importance As the researchers write, thyroid cancer “is one of the […]

(Beyond Pesticides, November 13, 2025) A study in Environmental Science & Technology shows that maternal exposure to organophosphate (OP) and pyrethroid insecticides adversely affects newborn health. Through amino acid and acylcarnitine metabolomics (the study of small molecules known as metabolites) with over 400 mother-infant pairs, this research analyzes metabolic pathways linking pesticide exposure to negative birth outcomes. “To our knowledge, this study is the first to reveal the effect of OP and pyrethroid insecticide exposure on neonatal metabolic signatures, which may elucidate a key role of metabolites in insecticide exposure and birth outcomes,” the authors state. In collecting maternal urine samples in the first and third trimesters, as well as neonatal blood samples after birth, OP and pyrethroid metabolites and metabolomic biomarkers are assessed. Notably, the authors report: “Results indicated that third-trimester maternal urinary levels of 3- phenoxybenzoic acid (3-PBA) and diethyl dithiophosphate (DEDTP) were negatively associated with birth weight. Specifically, a one-unit increase in their ln-transformed [natural logarithm form] concentrations was associated with a 1.508% decrease in birth weight for 3-PBA and a 1.366% decrease for DEDTP.” Additionally, the analyses show that OP and pyrethroid exposure is associated with “disrupted neonatal amino acids and acylcarnitine profiles, with patterns varying […]

(Beyond Pesticides, November 11, 2025) A study published in Cardiovascular Toxicology (July 2025) finds significant associations between Gulf War deployment-related toxic chemical exposure hazards and various adverse health outcomes, including heightened risk of atherosclerotic cardiovascular diseases (ASCVDs), such as “heart attack, coronary heart disease, stroke, transient ischemic attack, and peripheral vascular disease.” While there were no significant associations found directly between pesticide products and these adverse health effects, researchers attribute this to limited sample sizes and wide confidence intervals as part of the study methodology. Further research is necessary to build on this study, given the preponderance of scientific evidence linking pesticide exposure to heightened health risks to the cardiovascular system. On the issue of statistical significance, the authors state the following: “There may be difficulty [for survey respondents] remembering the[ir] military exposure history since the survey was completed nearly 25 years after the Gulf War.” While it is difficult to pinpoint pesticide exposure as a cause of illness among the toxic mixtures to which service members are exposed, there has been recognition by the Veterans Administration (VA) of diseases that are directly related to military service. Beyond Pesticides previously reported that the VA has established 20 burn pit and […]

(Beyond Pesticides, November 7, 2025) There is little dispute that modern industrial culture has produced a constellation of related chronic conditions contributing powerfully to human disease. In recent decades, attention has begun to focus on the developmental origins of health and disease—prenatal exposures to pesticides, for example, that contribute to diseases in adulthood, such as cardiovascular and metabolic problems, along with the combination, known as cardiometabolic syndrome. Cardiometabolic disorders include obesity, hypertension, cholesterol imbalances, and insulin resistance. The usual suspects blamed for the syndrome are poor diet, physical inactivity, and genetic predisposition. These are all well-established risk factors, but they fail to fully account for the sharp rise in cardiometabolic syndrome globally. Obesity prevalence has doubled and diabetes quadrupled over the last 40 years, according to the Non-Communicable Diseases (NCD) Risk Factor Collaboration. In a study on early life exposure to a pesticide mixture, researchers analyze sex differences in cardiometabolic outcomes from prenatal and early life. The study was conducted by an international team of scientists led by Ana M. Mora, M.D., of the Center for Environmental Research and Community Health at the University of California, Berkeley, using data from the Center for the Health Assessment of Mothers and Children of […]

(Beyond Pesticides, November 6, 2025) The report, Designed to Kill: Who Profits from Paraquat, and accompanying interactive storymap, unpacks the supply chain of the infamous herbicide paraquat and underscores the true costs of pesticide products, from manufacturing to use in the fields. This report is part of a larger initiative, the Pesticide Mapping Project—“a collaborative research series that illustrates the health and climate harms of pesticides across their toxic lifecycle: including fossil fuel extraction, manufacturing, international trade, and application on vast areas of U.S. land.” Top Highlights This report highlights, among other notable points, “that every stage of the paraquat supply chain—which spans the globe—emits greenhouse gases and toxic air pollutants.” With SinoChem as the lead producer and player in the paraquat market, the Chinese government-owned pesticide company’s supply chain “includes fossil fuel extraction in Equatorial Guinea and Saudi Arabia, chemical manufacturing in India, Germany, and the United Kingdom, international chemical shipping, and final formulation and distribution in the United States.” Paraquat is not currently manufactured in the U.S., accounting for imports of “between 40 and 156 million pounds of paraquat each year, according to the last eight years of pesticide import records available from the private database.” Despite the […]

(Beyond Pesticides, November 4, 2025) A study of earthworms published in Environmental Science & Technology highlights how chemical mixtures can have both synergistic and species-specific effects, threatening the soil microbiome and overall soil health. In exposing two species, Eisenia fetida and Metaphire guillelmi, to the weed killer glyphosate alone and in combination with urea, a form of synthetic nitrogen fertilizer, the researchers find enhanced toxicity with co-exposure as well as varying health effects between the two species. These results emphasize the need to test a wide variety of nontarget organisms for impacts from environmental contaminants, since species, even within the same genus or family, can exhibit vastly different effects. Glyphosate, as one of the most widely used herbicides worldwide, is highly researched, with a multitude of studies linking the weed killer to effects on humans, wildlife, and soil ecosystems. Since simultaneous application of glyphosate and urea frequently occurs in agriculture, the effects of this mixture on earthworms are crucial for understanding the overall impacts on soil health. In exposing the two species to the individual compounds and as a mixture, the authors report increased glyphosate residues in earthworm gut contents, reduced body weight, aggravated intestinal tissue damage, sharply decreased digestive […]

(Beyond Pesticides, October 31, 2025) A review in Lancet Neurology provides a clear snapshot of the state of scientific understanding of Parkinson’s disease and how medicine and policy could be improved by shifting focus to the primary causes of the disease, namely environmental toxicants, and to emphasize prevention rather than devoting resources only to treatments and a cure. The study, led by Ray Dorsey, M.D. of the Atria Research and Global Health Institute and the University of Rochester Medical Center, focuses on three classes of environmental toxicants: pesticides, dry cleaning and degreasing chemicals, and air pollution. Because these are pollutants introduced by humans, the authors say, they should be controllable, and “Parkinson’s disease could be thus largely preventable.” According to the review, in the last five years, new evidence has accumulated about three types of pesticides of particular concern. They are not all insecticides, which is the pesticide category most associated with neurological damage. Paraquat is a herbicide used on corn, soybeans, and cotton. Rotenone is used to kill rats and insects. Organochlorine insecticides comprise the third class. The review notes that there are many other pesticides that are neurotoxic and may have common mechanisms of action leading to Parkinson’s and […]

(Beyond Pesticides, October 29, 2025) A study published in Environment International evaluates residues of individual and mixtures of endocrine-disrupting chemicals (EDCs), including pesticides, and finds an association between exposure and hyperactive behavior in children. The researchers evaluated urine samples from over 800 preschoolers, identifying and statistically analyzing concentrations of 22 EDCs, and finding that nine of these chemicals are significantly associated with hyperactivity trajectories and EDC mixtures are positively associated with hyperactive behavior, noting the strongest association in girls.  “The current study indicates the adverse health effects of exposure to mixtures of EDCs among preschoolers, and suggests gender specificity in these effects,” the researchers state. They continue, “This highlights the importance of focusing on multi-pollutant exposure in early childhood.”  Study Importance  “Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children, which has become one of the main factors leading to the burden of disease in children and adolescents worldwide.” The authors continue: “Its core symptoms are high levels of inattention and/or hyperactivity/impulsivity during the preschool period. A meta-analysis showed that the overall prevalence of ADHD in children in China over the past 15 years was as high as 6.2%, and has been increasing over recent years.”  In comparison, according […]

(Beyond Pesticides, October 24, 2025) A literature review published in Science of the Total Environment reports numerous peer-reviewed studies associating prenatal and childhood pesticide exposure to measurable alterations to children’s immune systems, including indicators of immunosuppression and increases in pro-inflammatory cytokines, among other adverse health effects. These immune system alterations are linked to higher infection risk and potentially contribute to autoimmune diseases and allergies later in life. For over four decades, Beyond Pesticides has tracked the peer-reviewed science and identified a preponderance of evidence linking pesticide and chemical-dependent pest management to adverse human and ecological health effects. In this spirit, public health and environmental advocates continue to call for a wholesale transition to organic land management and organic pest management as biodiversity, public health, and climate crises continue to mount. This mission supports the growth of the Parks for a Sustainable Future Program, where nineteen cities in eleven states across the country engage in pilot projects to transition parks, playing fields, and schoolyards to organic management practices and protect the health of children. Background and Methodology “This study aimed to evaluate the extent of immunotoxicity and correlation between exposure to pesticides and immune system alterations in children under five years […]

(Beyond Pesticides, October 21, 2025) A study, published in International Journal of Hygiene and Environmental Health, calculates cumulative dietary pesticide exposure and finds a significant positive association between pesticide residues in food and urine when analyzing over 40 produce types. The research uses data for 1,837 individuals from the 2015–2016 National Health and Nutrition Examination Survey (NHANES) and compares them to biomonitoring samples of the participants. According to the researchers, “Here we show that consumption of fruits and vegetables, weighted by pesticide load, is associated with increasing levels of urinary pesticide biomarkers.” They continue, “When excluding potatoes, consumption of fruits and vegetables weighted by pesticide contamination was associated with higher levels of urinary pesticide biomarkers for organophosphate, pyrethroid, and neonicotinoid insecticides.” The NHANES data is derived from a national biomonitoring survey from the U.S. Centers for Disease Control and Prevention (CDC), which collects information about consumption of fruits and vegetables as well as urine samples. Background As the study authors explain: “Hundreds of millions of pounds of synthetic pesticide active ingredients are used every year in the United States, and pesticide exposure can occur through food, drinking water, residential proximity to agricultural spraying, household pesticide use, and occupational use. Pesticide […]

(Beyond Pesticides, October 3, 2025) A study published in European Journal of Nutrition finds that consumption of organic animal-based and plant-based foods is positively associated with higher cognitive scores. Among women, there was both better cognitive function before testing (at baseline) and up to a 27 percent lower MCI [mild cognitive decline] score over the course of the study period for participants identifying as organic consumers, even if there was consumption of just one of the seven food categories. Over the 3.7-year study period, the authors conclude, “Our study found that organic food consumption was associated with higher cognitive scores for both sexes, yet the association with reduced incidence of MCI was observed exclusively in female participants.” While it is important to note that additional research is necessary to corroborate these results, these findings support the calls of environmental and public health advocates across the country who are calling for political leaders to take action by mandating organic-sourced meals for public institutions and programs, including National School Breakfast and School Lunch Program, hospitals, public universities, and other institutions. Background and Methodology The data for this study is drawn from robust datasets for the U.S. population, including 2012 data from University […]

(Beyond Pesticides, October 1, 2025) A novel study in Scientific Reports combines computational analyses with toxicological data to identify pathways affected by exposure to the weed killer glyphosate. The analyses identify glyphosate targets that correlate with kidney injury and kidney cancer, revealing pathways with significant glyphosate-induced alterations, including the dysregulation of nitrogen metabolism that leads to ammonia accumulation and oxidative stress, both of which contribute to renal (kidney) damage and carcinogenesis (development of cancer). “This study provides a comprehensive investigation into the molecular mechanisms by which glyphosate may contribute to kidney injury and kidney cancer, employing an array of bioinformatics tools for target prediction, toxicity assessment, pathway enrichment analysis, molecular docking and molecular dynamics simulation,” the researchers state. The results of the analyses and simulations highlight the molecular mechanisms underlying glyphosate’s nephrotoxic (damaging to kidneys) and carcinogenic (cancer-causing) effects. Study Importance and Background Glyphosate, known as a broad-spectrum systemic herbicide, has been used for agricultural and nonagricultural purposes for decades and is the most extensively used herbicide worldwide. This widespread use is largely due to its application to genetically engineered, glyphosate-tolerant crops. Both glyphosate and its main metabolite (breakdown product), aminomethylphosphonic acid (AMPA), are detected in water, soil, and food, […]

(Beyond Pesticides, September 24, 2025) A novel study of chronic toxicity of the neonicotinoid insecticide thiamethoxam to honey bees (Apis mellifera), published in Insects, finds sublethal effects that threaten the survival of bee larvae and the health of bee colonies. “We evaluated the effects of thiamethoxam on the entire larval development cycle of reproductive bees and conducted a comparative analysis, demonstrating that thiamethoxam significantly alters ecdysone [a hormone that controls molting in insects] and juvenile hormone titers [hormones for insect growth] in both queen and drone larvae, impairing metamorphosis and reproductive development,” the authors state. Risk assessments and scientific literature focus primarily on honey bee workers, rarely including how pesticides can impact queen and drone bees that are necessary for stable colonies. In focusing on this data gap, the researchers reveal that the survival rate of bee larvae decreases gradually with increasing doses of thiamethoxam, adding to the wide body of science on pesticide-related threats to honey bee health. (See Beyond Pesticides’ What the Science Shows on Biodiversity page for more information, as well as Daily News coverage on risk assessments here, here, and here.) Honey bees provide crucial ecosystem services as pollinating insects and play a vital role in […]

(Beyond Pesticides, September 18, 2025) Published in Environmental Toxicology and Pharmacology, a study of earthworms (Eisenia fetida) evaluates the toxicity of environmentally relevant levels of three fluorinated pesticides (fluxapyroxad, fluopyram, and bixafen) through a 56-day soil exposure experiment. The dose- and time-dependent results reveal that effects on growth and reproduction occur at elevated concentrations, with weight loss and reduced offspring occurring from energy depletion and reproductive organ damage. Other implications escalate with concentration as well, including antioxidant system failure and DNA damage. As the authors summarize, “These findings highlight the mechanisms of fluorine-containing pesticide toxicity in earthworms, emphasizing their potential to disrupt soil ecosystems.” Fluorine-containing pesticides are widely used in agriculture, yet the chronic effects on soil and soil organisms are not fully considered in regulatory review. Research comparing the similarities and differences in the impacts on nontarget organisms from fluorinated pesticides is lacking, with the current study beginning to address the urgent need to close this gap. “Data indicate that among more than 100 newly developed pesticides, fluorine-containing pesticides constitute nearly half, making them a focal point in the development of the global pesticide industry,” the researchers state. As representatives of the fluorinated pesticides class, particularly succinate dehydrogenase inhibitors […]

(Beyond Pesticides, September 10, 2025) Published earlier this year, a review of over 1,700 studies in Nature Communications finds pesticides affect a diverse range of nontarget organisms and contribute to global biodiversity loss. The authors* reveal “negative responses of the growth, reproduction, behaviour and other physiological biomarkers within terrestrial and aquatic systems” for nontarget plants, animals, and microorganisms. “To our knowledge, there has been no systematic and overarching synthesis of how different types of pesticides affect the diversity of multiple non-target eukaryotic and prokaryotic organisms across all trophic levels,” the researchers write. They continue, “Furthermore, current syntheses have not considered how the impacts of pesticides differ globally across climatic zones or for major mechanisms of exposure, such as those acting in aquatic or terrestrial environments.” In particular, pesticide regulatory risk assessments analyze a limited range of model species, including rats, zebrafish, clawed frogs, honeybees, and earthworms, among others. As such, they are unlikely to capture the variety of responses to pesticide exposure seen across the diversity of species and communities found in both managed and natural systems,” the authors state. *Authors include Beyond Pesticides 2023 National Forum speaker Dave Goulson—see the Daily News on his keynote address here. Research Results […]

(Beyond Pesticides, September 5, 2025) A study in Journal of Agricultural and Food Chemistry finds permethrin, a commonly used synthetic pyrethroid insecticide, to be disruptive to the gut microbiome, altering microbiota and leading to increased formation of fat cells (adipogenesis) and metabolic disorders. With an aim to “comprehensively elucidate the effects of permethrin on gut microbiota, lipogenesis, and the associated molecular mechanisms,” the study explores the adverse effects of permethrin exposure in adult mice through multiple experiments. “Our study provides the first in vivo [in a living organism] evidence suggesting a potentially causal relationship between permethrin exposure and the development of obesity, potentially mediated by specific gut microbiota-derived metabolites,” the researchers explain. They continue, “Notably, this work is the first to define a distinct microbiota−metabolite−host axis as a critical mediator of environmental toxicant-induced metabolic dysfunction.” Permethrin is widely used as an insecticide on crops, such as cotton, corn, and wheat, as well as on livestock, in indoor and outdoor areas, and for treating lice and scabies. Mosquito abatement programs often utilize permethrin, further adding to the various exposure routes of this neurotoxic chemical. (See additional uses and health effects of permethrin in Beyond Pesticides’ Gateway on Pesticide Hazards and Safe […]

(Beyond Pesticides, August 28, 2025) The U.S. Environmental Protection Agency (EPA) on August 12, 2025, released a statement, “EPA Announces Action to Protect Endangered Species from Insecticide Methomyl,” in which the agency announced label changes for methomyl, a carbamate insecticide, with mitigation measures that are being criticized as allowing great risks to biodiversity and human health. The label changes, following the National Marine Fisheries Service’s (NMFS) final biological opinion issued on January 1, 2024, actually establish mitigation measures to be determined by applicators using the Bulletins Live! Two website prior to use. EPA claims that this grower determined action will meet the standards of the Endangered Species Act (ESA) by “reduc[ing] runoff and spray drift from treated areas into species’ habitats.” However, the process does not include monitoring and oversight to determine whether the rigorous standards of ESA are being met. The agency says that mitigation tracking is “at the field or farm level,” but it is not required to be submitted to the agency. EPA announced on August 20 that it is holding a 90-minute public webinar on September 16, 2025, at 2:00 PM ET to provide information on the ecological runoff/erosion and spray drift mitigation measures that can […]

(Beyond Pesticides, August 26, 2025) A scientific review in World’s Poultry Science Journal highlights the adverse health effects on avian species from exposure to the widely used weed killer glyphosate (Roundupᵀᴹ) throughout the process of poultry production. The herbicide enters the poultry production system through residues in genetically engineered feed. An earlier article in Scientific Reports concludes that glyphosate’s (GLP) “widespread application on feed crops leaves residues in the feed,” while residues are “found to be common in conventional eggs acquired from grocery stores.” In analyzing the biochemical, toxicological, and ecological impacts of glyphosate on poultry, particularly chickens, the authors find a wide body of evidence linking glyphosate and its metabolite (breakdown product) aminomethylphosphonic acid (AMPA) to debilitating hazards that extend beyond mortality. These sublethal effects include disruption of the gut microbiome and gastrointestinal disease; decreased productivity and diminished reproductive health; hepatic and kidney toxicity; growth and developmental impacts, including teratogenicity and embryotoxicity; endocrine disruption and oxidative stress; and impaired immune functions. The effects of glyphosate, as have long been documented in the scientific literature and covered by Beyond Pesticides here, range from negative impacts on biodiversity and the environment to food safety risks and human health implications. Residues of […]

(Beyond Pesticides, August 19, 2025) A new study from Argentina highlights the importance of applying the concept of the exposome (total exposures over lifetime) as a scientific framework, the value of biomonitoring, and findings of adverse pregnancy outcomes. The study documents the presence and effects of pesticides on maternal and fetal health during pregnancy. The results show that pregnant Argentine women are exposed to dozens of pesticides, and that certain mixtures of these chemicals are associated with harm to pregnancy outcomes, especially among rural women. The exposome, the authors write, comprises the “non-genetic factors that may be involved in the development or aggravation of human disease. The prenatal exposome includes all environmental chemicals that the mother is exposed to during pregnancy (maternal exposome) and those chemicals that reach the placenta and fetus from the maternal circulation (fetal exposome).” The authors emphasize that understanding the exposome almost by definition requires studying mixtures of environmental chemicals rather than analyzing the effects of each in isolation. The second important aspect of the study is its use of biomonitoring. The researchers analyzed urine samples from 90 pregnant women in various gestational stages from rural and urban regions of Argentina. The researchers also collected demographic […]

(Beyond Pesticides, August 18, 2025)  With pesticide manufacturers pushing to stop cancer victims (and others suffering adverse effects) from suing them under longstanding ”failure to warn law,“ U.S. Senator Cory Booker (D-NJ) is proposing to uphold this unequivocal right to protection. Senator Booker has introduced the Pesticide Injury Accountability Act (S. 2324) to protect the rights of farmers and consumers to hold pesticide manufacturers responsible for the harm caused by their toxic products. This effort comes in the wake of congressional and state legislative attacks on “failure-to-warn” liability claims that are taking place in response to extraordinary jury verdicts against Bayer/Monsanto for harm caused by glyphosate weed killer products like Roundup.ᵀᴹ 📣 Beyond Pesticides, with allied organizations across the U.S., is asking the public to “Tell your U.S. Senator to co-sponsor S. 2324, the Pesticide Injury Accountability Act.” This bill will amend the Federal Insecticide, Fungicide, and Rodenticide Act of 1972 (FIFRA) to create a federal right of action for anyone who is harmed by a toxic pesticide.  Despite growing peer-reviewed scientific evidence linking widely used pesticides to a host of health harms, including cancers, birth defects, endocrine disruption, Parkinson’s disease, and infertility, the chemical industry and its allies in elective office are pushing to deny victims access to […]

(Beyond Pesticides, August 14, 2025) A review in Clinical and Experimental Obstetrics & Gynecology links various classes of environmental pollutants including pesticides and per- and polyfluoroalkyl substances (PFAS), both of which Beyond Pesticides has extensively covered, to adverse effects on the female reproductive system and common mechanisms of toxicity. These chemicals “disrupt the hypothalamic-pituitary-gonadal axis (HPG), impair ovarian function, and contribute to reproductive dysfunction through mechanisms such as oxidative stress, hormonal disruption, and epigenetic [gene expression or behavior] modifications,” the authors say. This leads to menstrual irregularities, infertility, and pregnancy complications, as well as increases in the risk of reproductive system disorders such as endometriosis, polycystic ovary syndrome (PCOS), and ovarian cancer, among others. “Additionally, transgenerational effects mediated by epigenetic modifications, germ cell damage, and placental transfer may adversely affect offspring health, increasing the risk of reproductive dysfunction, neurodevelopmental disorders, metabolic diseases, and cancer,” the researchers explain. This study, integrating recent epidemiological and experimental findings, provides an overview of major chemical classes that threaten women’s health and highlights the need for immediate action. As the authors point out, female reproductive health is important not only for those who choose to plan for a family but also for the overall well-being […]

(Beyond Pesticides, August 13, 2025) The data on the adverse effects of the insecticide chlorpyrifos, still widely used in food production, continued to accumulate with the latest being a study published in PLOS One that finds perinatal exposure to the chemical in mice can alter sleeping patterns, lead to brain inflammation (particularly in female individuals), and impact gene expression linked to immune response and epigenetic effects. The adverse health effects are greater overall in female mice than male mice, emphasizing the significance of disproportionate impacts across species. Chlorpyrifos has been a threat to human and ecological health for decades, originally as a general-use pesticide for homes, gardens, and agriculture, and then restricted to most nonresidential uses in 2000. Currently, the chemical’s permitted uses include food and feed crops, golf courses, as a non-structural wood treatment, and adult mosquito control for public health (insect-borne diseases) uses only. According to health and environmental advocates, there is a long history of U.S. Environmental Protection Agency (EPA) failure to adequately protect human and environmental health from chlorpyrifos, which is linked to endocrine disruption, reproductive effects, neurotoxicity, brain, kidney, and liver damage, and birth and developmental effects. It took 21 years after negotiating a stop […]

(Beyond Pesticides, August 7, 2025) The novel study published in Arthritis & Rheumatology is the largest investigation of rheumatoid arthritis (RA) in women to date, finding evidence of heightened risks when exposed to insecticides through data collected from over 400 eligible women in the Agricultural Health Study (AHS). AHS participants include a cohort of thousands of licensed pesticide applicators and their spouses from Iowa and North Carolina, with this particular study as the first to consider the link between pesticide exposure and RA as it affects women’s health.   “Growing evidence suggests farming and agricultural pesticide use may be associated with rheumatoid arthritis (RA), but few studies have examined specific pesticides and RA among farm women, who may personally use pesticides or be indirectly exposed,” the study authors explain. The findings reveal that organochlorine insecticides that continue to persist in the environment, as well as organophosphate and synthetic pyrethroid pesticides used in public health or residential settings, correlate with RA diagnoses in women.  As shared in previous Daily News, for the most part organochlorine pesticides, including dichlorodiphenyltrichloroethane (DDT), are no longer used worldwide, but the legacy of their poisoning and contamination persists. These compounds are primarily made up of chlorine atoms, […]