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Daily News Blog

25
Mar

Review Links Pesticide-Induced Mechanisms of Cell Death to Increased Risks of Liver Diseases

(Beyond Pesticides, March 25, 2026) A literature review, published in Diseases, showcases the wide body of scientific literature linking pesticide exposure to liver disease through both apoptotic (programmed cell death without triggering inflammation) and non-apoptotic (regulated cell death with an inflammatory response) pathways. “In summary, our study confirms that pesticides carry significant health risks and sheds light on the underreported mechanisms that can drive their overall toxicity as a whole and hepatotoxicity [liver] in particular,†the researchers state.  In addition to analyzing the science on pesticide-induced apoptosis, the researchers “systematically illustrated an underappreciated mechanism of pesticide-induced overall and hepatic toxicity, i.e., the ability to induce non-apoptotic regulated cell death (RCD) pathways such as ferroptosis, necroptosis, and pyroptosis.†They continue, saying, “Importantly, our review stresses the contribution of pesticide-induced cell death modes to inflammation and immunity regulation in hepatic pathology.†Background Pesticides, as a comprehensive group, can be subdivided into classes based on their targets: rodenticides (rodents), herbicides (weeds), insecticides (insects), fungicides (fungi), nematicides (nematodes), acaricides (mites and ticks), and bactericides (bacteria). The use of these pesticides, particularly in agriculture, has skyrocketed over recent decades. As the authors state: “In 2019, the total pesticide . . .

24
Mar

Pesticides in Drinking and Irrigation Water in Floriculture Region of Ecuador, Large Exporter of Flowers

(Beyond Pesticides, March 24, 2026) Published in Environmental Pollution, study results in the floriculture region of Ecuador find detections of neonicotinoid insecticides (NNI) and the herbicide atrazine in drinking and irrigation water. The biomonitoring data reported in an earlier journal article in the same region found a total of 23 compounds used as herbicides, insecticides, and fungicides, their associated metabolites (breakdown products), which include organophosphates, pyrethroids, and neonicotinoids. (See Daily News here.) Researchers from the University of Iowa, University of California, San Diego State University, and Universidad de San Francisco in Quito, Ecuador, determined that 1 in 5 households (20.5%) have detectable levels of one or more neonicotinoids in drinking water samples surrounding floricultural agricultural operations. This builds on previous research underscoring the nontarget pesticidal effects in communities near agricultural operations where the chemicals drift through the air and move into soil and water. Methodology and Results The authors report that, “This study focused on household tap water in proximity to floricultural plantations and in the ESPINA [Secondary Exposures to Pesticides among Children and Adolescents] participants’ homes with a range of NNI and total pesticides in urinary metabolite samples of the children.†They continue: . . .

23
Mar

Bipartisan Bill Challenges Trump Giving Bayer/Monsanto Liability Immunity for Glyphosate Harm

(Beyond Pesticides, March 23, 2026) After President Trump invoked the Defense Production Act of 1950 and issued an Executive Order (EO), Promoting the National Defense by Ensuring an Adequate Supply of Elemental Phosphorus and Glyphosate-Based Herbicides, U.S. Representatives Thomas Massie (R-KY) and Chellie Pingree (D-ME) stood up to say “no.†They introduced the No Immunity for Glyphosate Act (HR 7601) to undo the February 18 Executive Order, which is now being supported by a campaign to urge Congressional Representatives to cosponsor the bill.  With the EO’s declaration that contains no supporting documentation or findings, the U.S. government is granting Bayer/Monsanto immunity from lawsuits for adverse health effects or damage associated with the production, transportation, use, and disposal of the weed killer glyphosate. The executive order proclaims: “There is no direct one-for-one chemical alternative to glyphosate-based herbicides. Lack of access to glyphosate-based herbicides would critically jeopardize agricultural productivity, adding pressure to the domestic food system, and may result in a transition of cropland to other uses due to low productivity.  Given the profit margins growers currently face, any major restrictions in access to glyphosate-based herbicides would result in economic losses for growers and make it untenable for them . . .

20
Mar

“Biopesticides†Critiqued as Poorly Defined and Regulated, Challenging Safety Assumptions and Use

(Beyond Pesticides, March 20, 2026) Biopesticides represent a kind of Utopian destination in the landscape of agricultural sustainability. If only they could ensure planetary harmony. A review of botanical biopesticides in the March 11 issue of Toxics raises important questions that require scrutiny and review under the pesticide registration process and when used in organic systems under the Organic Foods Production Act. The term biopesticide can be misleading, and any replacements for synthetic pesticides cannot be taken only on faith. As Beyond Pesticides has noted previously, the U.S. Environmental Protection Agency’s (EPA) definition of biopesticides—“derived from such natural materials as animals, plants, bacteria, and certain mineralsâ€â€”is broad, vague, and used differently by different interests. EPA regulates biopesticides under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) in three categories: Substances that interfere with mating, such as insect sex pheromones, as well as various scented plant extracts that attract insect pests to traps; Microbial pesticides consisting of a microorganism (e.g., a bacterium, fungus, virus, or protozoan) as the active ingredient; and Plant-Incorporated-Protectants (PIPs), pesticidal substances that plants are genetically engineered to produce. The review by Sandra Petrovic, PhD, and Andreja Leskovac, PhD, of the University . . .

19
Mar

Pesticide Contamination of Important Microorganism Communities Moves to Protected Areas through Environment

(Beyond Pesticides, March 19, 2026) A study of water contamination in Protected Areas (PAs) in Brazil, published in Science of The Total Environment, highlights the pervasiveness of pesticides. “Our objective was to evaluate the effectiveness of these PAs in mitigating pesticide contamination in watercourses and to investigate how land use patterns influence the presence of pesticide residues,†the authors state. “We found pesticide compounds in biofilms [mutually beneficial community of microorganisms] both inside and outside PAs’ streams, with no buffer effect of these protected lands against herbicides, insecticides and fungicides, contrary to our expectations.†In analyzing epilithic biofilms, which are communities of microorganisms that adhere to submerged rocks and surfaces in aquatic ecosystems, the researchers find residues of 14 pesticide compounds and one metabolite across the 19 sampling sites, threatening aquatic organisms and ecosystem functioning. The authors say, “[M]onitoring epilithic biofilms in PAs provides valuable information by detecting pesticide compounds that analysis of surface water and sediments might miss.†Through various routes, such as runoff to waterways, leaching into groundwater, and aerial drift, pesticides are ubiquitous in the environment, even in remote and protected areas. As the testing of the freshwater epilithic biofilms in . . .

18
Mar

Study Highlights Benefits of Organic Agriculture for Pollinator Health, Building on Existing Research

(Beyond Pesticides, March 18, 2026) Researchers in Germany and Brazil investigated the biodiversity of agricultural landscapes in organic and non-organic areas in “bee hotels,†finding that there is a positive correlation between organically managed fields and numerous indicators of improved pollinator health, including an “increase in bee abundance, species richness, and diversity.†This study, published in Global Ecology and Conservation, builds on the breadth of existing research in recent years that underscores the adverse public health and biodiversity effects associated with a food system that is drenched in synthetic chemicals, as well as additional evidence of the ecological and economic benefits of organic agriculture. Methodology and Results Research for this study “was conducted at 17 sites in the southern part of Germany, Baden-Württemberg, including eight conventional and nine organic farming systems.†Researchers for this study are based at the Institute of Evolutionary Ecology and Conservation Genomics at Ulm University in Germany and the Laboratory for Bee Studies at the Federal University of Maranhão in São Luís, Maranhão in Brazil. The authors signed a “declaration of competing interest,†stipulating that “that they have no known competing financial interests or personal relationships that could have . . .

17
Mar

Genetically Modified Microorganisms Threaten Human and Soil Health; Full Extent of Hazards Not Regulated

(Beyond Pesticides, March 17, 2026) An article in Microorganisms by researchers from the U.S., Israel, and Australia analyzes the adverse health and environmental effects of genetic engineering and genetically modified organisms (GMOs), specifically genetically modified microorganisms (GMMs). As the authors state, the prevalence of genetic engineering has “accelerated the creation and large-scale environmental release†of GMMs, which “present unique, long-term risks to human and environmental health.†One of the authors, André Leu, DSc, spoke at the first session of Beyond Pesticides’ National Forum Series: Forging a Future with Nature in 2023. (See recording here.) This review provides risk scenarios of GMMs, showing the threat to ecological systems, particularly within the soil, and human health. As GMMs are “biologically active, self-replicating entities capable of rapid mutation and global dispersal†they present greater risks, and current regulatory frameworks do not adequately assess their potential harm. Genetically altering microorganisms, the most complex and diverse systems in biology, and creating new gene combinations with unknown implications, “has the potential to disrupt the functions, diversity, interactions, and impacts of microbes and microbiomes,†the researchers note. They continue: “This puts human and environmental health at risk. Worst-case scenarios include the . . .

16
Mar

Introduction of New Genetically Engineered Wheat Tied to Dangerous Pattern of Hazardous Pesticide Use

(Beyond Pesticides, March 16, 2026) On the brink of the first genetically engineered (GE) wheat to be introduced into the U.S. market, after the U.S. Department of Agriculture (USDA) approved it in August, 2024, groups are calling on Congress to instruct USDA to prohibit HB4 wheat and instruct EPA to prohibit the use of glufosinate herbicides on wheat. The herbicide on which the crop is dependent, glufosinate, is a highly toxic herbicide banned in the European Union because of its links to reproductive and developmental harm. The drought- and herbicide-tolerant wheat, known as HB4 GMO wheat, follows a long line of genetically engineered crops that have been allowed to be grown in the U.S., with Roundup ReadyTM (glyphosate-tolerant) soybeans being among the first crops allowed in 1996. While the introduction of this technology promised to reduce pesticide use (herbicides are included under the definition of pesticide), the exact opposite occurred, with the skyrocketing of herbicide use. (See Daily News review of a study by Charles Benbrook, PhD, “Impacts of genetically engineered crops on pesticide use in the U.S.—the first sixteen years.â€) The extraordinary increase in herbicide use associated with GE crops has been accompanied by . . .

13
Mar

Study Shows Widely Used Weed Killer To Contain PFAS, Further Threatening Health and the Environment

(Beyond Pesticides, March 13, 2026) In a press release on March 10, 2026, Public Employees for Environmental Responsibility (PEER) cites independent test data on the herbicide indaziflam with detections of per- and poly-fluoroalkyl substances (PFAS), the “forever chemicals†known for significant toxicity at low level exposure and high persistence. The product, Rejuvraâ„¢, is produced by Envu (a former division of Bayer) and “is being sprayed and considered for use across millions of acres of Bureau of Land Management (BLM) and US Forest Service land.†Scientific literature connects indaziflam and PFAS with adverse effects to human, soil, and biodiversity health, raising serious concerns about their wide use in agriculture and general land management of lawns, parks, playing fields, ornamentals, fence lines, rights-of-way, rangeland, open space, and Christmas trees. Background As a pre-emergent weed killer used to kill annual grasses and unwanted broadleaf plants, the fluoroalkyltriazine herbicide is broadly labeled for use in residential areas, commercial ornamental and sod production, forestry, and mostly orchard crops. While indaziflam is considered a “selective†herbicide, it actually kills and prevents germination of a wide range of broad-leaved plants and grasses and comes close to being a soil sterilant. . . .

12
Mar

Pesticide Exposure Again Linked to Neurotoxic Effects in Humans and Wildlife in Comprehensive Review

(Beyond Pesticides, March 12, 2026) The science connecting pesticide exposure to neurotoxicity continues to mount. A study in Discover Toxicology highlights neurotoxic pollutants as significant environmental threats, showcasing the adverse impacts on vertebrates’ neurological health from pesticides, including organophosphates, carbamates, and organochlorines. “These substances disrupt normal neurophysiological functions by impairing neurotransmission, generating oxidative stress, provoking neuroinflammation, and initiating neuronal cell death,†the authors say. They continue, “Such disturbances are linked to cognitive deficits, motor impairments, and abnormal neural development.†Neurological conditions can manifest as headaches, muscle weakness, tremors, paralysis, coordination challenges, vision loss, hallucinations, vertigo, seizures, memory loss, slurred speech, trouble breathing with minimal exertion, and more. The range of adverse effects from low-dose, long-term exposure and low-dose (or subchronic) exposure during developmental phases of life raises serious questions about the adequacy of the regulatory review of pesticides, which focuses on acute high and lethal dose exposure. One study on the neurotoxicity of pesticides, published in Chemosphere, concludes, “New regulatory and preventive measures to mitigate the neurotoxic effects of pesticides are needed.†(See also Daily News.) Even at low concentration, chronic exposure to pesticides and other environmental contaminants “poses serious ecological and health concerns†that . . .

11
Mar

Monsanto Brief Introduced as U.S. Supreme Court Considers Liability Immunity for Pesticide Manufacturers

(Beyond Pesticides, March 11, 2026) The Monsanto Company, founded in 1901 and acquired by the multinational corporation Bayer AG in 2018, submitted its opening brief to the Supreme Court of the U.S. (SCOTUS) last month, seeking liability immunity from lawsuits filed by product users who have been harmed but not warned about potential product hazards. The question before SCOTUS is: “Whether the Federal Insecticide, Fungicide, and Rodenticide Act, 7 U.S.C. 136 et seq., preempts a state-law failure-to-warn claim concerning a pesticide registered by the U.S. Environmental Protection Agency (EPA), where EPA has determined that a particular warning is not required and the warning cannot be added to a product label without EPA approval.â€Â If successful, the Court would be overturning (reversing) its 2005 decision in Bates v. Dow Agrosciences, 544 U.S. 431, which upheld EPA and state registration of pesticides as a floor of protection, without releasing manufacturers of the responsibility to warn for potential harm that is not required by EPA. Pesticide manufacturers propose the text for their product labels and EPA ensures compliance with its minimum requirements, which does not preclude them from disclosing potential adverse effects they know of or should have known. The Missouri case before the Supreme Court, Durnell v. Monsanto, on the cancer causing effects of the weed killer glyphosate (RoundupTM) resulted in a jury verdict (in 2023) of $1.25 million and the total number of jury verdicts and settlements may . . .

10
Mar

Pesticide and Antibiotic Resistance Genes: An Escalating Global Health Crisis

(Beyond Pesticides, March 10, 2026) An article in the Journal of Agricultural and Food Chemistry identifies pesticides, often neglected, as a core factor in the spread of antibiotic resistance genes (ARGs) in agricultural environments. With antibiotic and antimicrobial resistance growing and infections becoming untreatable and deadly, the World Health Organization (WHO) has identified the problem as a “silent pandemic.” The authors, from Yangzhou University in China, highlight the persistence of both pesticide residues and ARGs throughout the environment, with both being found in water, soil, air, animal manure, and the human gut. “Existing studies have fully confirmed that pesticides are not isolated in the agricultural ecosystem but deeply participate in the proliferation and spread of ARGs through direct coselection, indirect induction of multiple resistances, and promotion of horizontal gene transfer, forming a combined pollution risk that superimposes on the traditional sources,†the authors note. The now well-known phenomenon of horizontal gene transfer—the movement of genes in bacteria from one bacterial species to another, which is facilitated by phages—means that ARGs in those (possibly harmless) bacteria can move to bacteria that cause disease in plants or humans. As stated in previous Daily News posts, . . .

09
Mar

EPA Asked to Deny Proposal To Use a New Not-Registered PFAS Pesticide under “Emergency†Waiver

(Beyond Pesticides, March 9, 2026) Policy and toxicology are slated to collide as the U.S. Environmental Protection Agency (EPA) considers allowing the use of a PFAS pesticide by invoking an emergency waiver process in federal pesticide law. If authorized, EPA’s decision will permit the use of an unregistered pesticide under an emergency waiver provision—in this case an emergency caused by weed resistance to weed killers (herbicides) on the market. EPA is accepting public comments until March 16, 11:59pm EDT. Beyond Pesticides is urging the public to object to EPA approval by writing to EPA and Congress stating that herbicide resistance is not an emergency and PFAS chemicals must not be broadcast in the environment.  The pesticide that is being requested for use is a new not yet registered, herbicide tetflupyrolimet (TFP), which is a PFAS chemical according to the definition of the Organisation for Economic Co-operation and Development (OECD). The fact that the chemical is not registered by EPA means that it has not been reviewed in accordance with all the safety assessments reviewed under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). The states applying for the exemptions under Section 18 of FIFRA—Missouri and Arkansas—claim that there is an . . .

06
Mar

Farm Bill Strips Protections from Pesticides for Farmers, Consumers, and the Environment

(Beyond Pesticides, March 6, 2026) The Farm Bill—the Farm, Food, and National Security Act of 2026, H.R. 7567—reported out of the Agriculture Committee in the U.S. House of Representatives yesterday strips environmental and public health protections from pesticides, reversing over 90 years of environmental laws adopted by Congress to protect farmers, consumers, and the environment that stretch back to the first Farm Bill in 1933. The Committee rejected the Protect Our Health Amendment, sponsored by Rep. Chellie Pingree (D-ME), which would have ensured that the final bill maintain three core safeguards in current law: (i) Judicial review of chemical manufacturers‘ failure to warn about pesticide hazards; (ii) Democratic right of local governments in coordination with states to protect residents from pesticide use; and, (iii) Local site-specific action to ensure protection—the safety of air, water, and land from pesticides under numerous environmental statutes. All Republicans and one Democrat (Rep. Adam Gray, D-CA) on the Committee blocked the Pingree amendment. The Agriculture Committee bill adversely affects a wide range of social and conservation issues, including the protection of family farms, food security, environmental and public health, local and state authority, and judicial review, according to a cross-section . . .

06
Mar

North American Birds’ Decline Associated with Agriculture

(Beyond Pesticides, March 6, 2026) Does humanity want to live in a world without birds? This may seem like an extreme question, but a new study in Science concludes that, without changes in human behavior, just such a world may be on the horizon. This would be a tragedy of colossal proportions, not only for the ecosystem services birds provide, but for the meaning of human life and a healthy biosphere. The oldest human-made image of a bird is 40,000 years old. The new study, by Czech environmental scientist François Leroy, PhD, and two colleagues from The Ohio State University, measured local population abundances of 261 North American bird species between 1987 and 2021. They also measured the speeds at which the species’ populations rose or fell. The study was based on data from the North American Breeding Bird Survey, a program of the U.S. Geological Survey in coordination with the Canadian Wildlife Service. This survey involves direct observations of bird populations along roadsides during breeding season. The program was created in the mid-20th century in response to the severe mortalities associated with the use of DDT, highlighted by Rachel Carson in her . . .

05
Mar

USRTK Spotlights Bayer-Monsanto Ties to Trump Administration, as Company Pushes for Immunity from Lawsuits

(Beyond Pesticides, March 5, 2026) In a deep analysis of public records, U.S. Right to Know (USRTK), a nonprofit newsroom and public health research group, discloses significant financial ties between Bayer-Monsanto, lobbying firms, and the second Trump Administration, raising concerns about basic safeguards to curb corporate influence over federal policymakers. The USRTK tracker and report, “Tracing Bayer’s ties to power in Trump’s Washington,†(see more) finds that there have been significant lobbying investments by the multinational pesticide corporation just in the past year, including:  “At least $9.19 million on federal lobbying in [2025]â€;   “16 key administration officials with ties to Bayer’s lobbying or legal network. Bayer and its lobbyists have access to people in power at the White House, U.S. Department of Agriculture, the Environmental Protection Agency and even those in high level positions closest to Trumpâ€;  “45 people registered to lobby for Bayer under the Lobbying Disclosure Act, and at least 13 outside lobby firms – seven of which are now among the highest-paid firms in D.Câ€; and,  “More than 30 senior officials at lobby firms retained by Bayer have direct ties to Trump, having worked in one or both of his administrations or political campaigns.â€Â  The report . . .

04
Mar

Agricultural Pesticide Exposure Heightens Risks of Kidney Cancer in Men and Women, Study Finds

(Beyond Pesticides, March 4, 2026) In the International Journal of Epidemiology, researchers from France assess the risks of kidney cancer with a wide range of agricultural activities and tasks, finding that occupational exposure heightens kidney cancer risk. In studying participants from the French AGRIculture and CANcer cohort (AGRICAN) with incident kidney cancer, elevated risks of disease development between 25-56% are documented for both men and women engaging in agricultural activities. In men, the authors find increased kidney cancer in those “working with rapeseed and sunflowers, and tasks related to other crops such as corn, wheat/barley, beet, and tobacco.†In women, an increased risk is noted for winegrowers and corn growers. “Pesticide use (on fields and/or seeds) was associated, for both sexes, with these crops, showing exposure-response relationships with crop area and work duration,†the researchers state. This study, of a large cohort of agricultural workers, highlights the disproportionate risks of adverse kidney health to farmworkers directly handling pesticides or encountering pesticide residues on recently treated products. According to the World Cancer Research Fund, kidney cancer is the 14th most common cancer worldwide, affecting men more often than women. Kidney cancer incidence and mortality have . . .

03
Mar

Studies Find Genetic and Epigenetic Effects from Pesticide Exposure, Threatening Future Generations

(Beyond Pesticides, March 3, 2026) Research published in Critical Reviews in Toxicology (CRT) and Proceedings of the National Academy of Sciences (PNAS) documents the genetic and epigenetic (changes to gene function without altering the DNA sequence) effects to pesticide-exposed groups through early-life exposure and from transgenerational inheritance (passed down through generations). These studies highlight the complex nature of mechanisms of toxicity, as well as the various pesticide exposure routes that begin even prior to conception. The analyses evaluate general and specific pesticide exposure as reported in observational and laboratory research. Through a systematic review and meta-analysis of studies on “DNA damage, cytogenetic damage, DNA methylation, or gene expression outcomes associated with prenatal and early childhood pesticide exposure,†the CRT authors link genotoxic mechanisms and epigenetic alterations to adverse health outcomes while the PNAS study shows pesticide-induced epigenetic alterations in mammals across 20 generations that “suggest the maternal and paternal lineages can both induce and inherit epigenetic alterations that influence disease (e.g., kidney, testis, ovary, prostate) incidence, reproductive health (e.g., parturition, infertility), and overall fitness generationally.†As the CRT study states: “One of the main ways pesticides can cause harm is through genotoxicity—their ability to . . .

02
Mar

GOP Farm Bill Goes to Committee Amid Broad Opposition to Provisions that Eliminate Protections from Pesticides

(Beyond Pesticides, March 2, 2026) In advance of deliberations on the Farm Bill tomorrow, March 3, in the Agriculture Committee of the U.S. House of Representatives, opposition to the GOP-proposed legislation has been widely expressed by farm, environmental, consumer, and social justice organizations. The bill, the Farm, Food, and National Security Act of 2026, H.R. 7567, is a dramatic departure from previous Farm Bills going back to the first one in 1933, which began a process of integrated policy to address family farmers’ sustainability, land conservation, energy, climate, and food security. Discarding the traditional bipartisan process used to draft the Farm Bill, the Republican leadership has instead proposed a measure that has garnered across-the-board disapproval, except from those representing the vested interests of chemical companies and agribusiness. In order to uphold fundamental protections from pesticides for farmers, consumers, and the environment, a campaign has emerged to urge U.S. Representatives to support Rep. Pingree’s Protect Our Health Amendment (removes Sections 10205-10207), move to strike Sections 10201-10204 and 102011, and support the No Immunity for Glyphosate Act provisions. Without a comprehensive overhaul, this campaign is urging a vote against the Farm Bill. Central to the GOP Farm Bill, released by . . .

27
Feb

Benefits of U.S. Organic Production Highlighted in Evidence-Based Research that Supports an Expedited Transition

(Beyond Pesticides, February 27, 2026) Researchers at Prairie View A&M University in Texas published in the journal Sustainability a study of organic agricultural systems from 1960 to 2021, concluding that “the outlook for U.S. organic fruit and vegetables is encouraging, supported by expanding consumer demand, government support, and improved conditions for international trade.†While delivering upbeat findings, including health benefits, the study identifies tremendous obstacles to entry into organic farming, including the limited support for alternative pest management and pest control systems in the United States in recent modern history, compared to the assistance provided for highly subsidized, petrochemical-dependent agricultural practices. Public health and environmental advocates continue to advocate for a wholesale transition to organic pest management, including calls for U.S. Representatives and Senators to cosponsor the Opportunities in Organic Act! Study Methodology, Background, and Findings The authors of this literature review arrived at the following conclusions on research trends for human health and environmental impacts of organic systems (for further analysis, the numbers below list citations from their report): “[O]rganic food has been documented to have higher antioxidant capacity, acidity, and phosphorus as well as lower levels of cadmium, pesticides, and other chemicals (18–22). . . .

26
Feb

Women in Agriculture at Elevated Risk of More Aggressive Breast Cancer from Pesticides, Study Finds

(Beyond Pesticides, February 26, 2026) Published in PLOS ONE, research in Brazil “analyzed the impact of occupational/household chronic exposure to pesticides on the clinicopathological profile of breast cancer in rural women from Paraná southwest, a predominantly rural landscape with large pesticide uses,†finding that “pesticide exposure favors the occurrence of more aggressive breast cancer.†The study highlights the disproportionate risks of pesticides to farmworkers, focusing on women, as it compares exposed and unexposed populations and breast cancer tumor/disease characteristics. One of the study authors, Carolina Panis, PhD, discussed her earlier research at the Beyond Pesticides’ 42nd National Forum Series, The Pesticide Threat to Environmental Health: Advancing Holistic Solutions Aligned with Nature. In her previous work, Pesticide exposure and increased breast cancer risk in women population studies, Dr. Panis documents a number of pesticides that “can increase the risk of BC [breast cancer] development through various mutagenic [genetic mutations] and nonmutagenic mechanisms and can act directly as carcinogens or indirectly as biochemical modifiers and hormonal deregulators. The underlying mechanisms include endocrine disruption; genotoxicity; epigenetic changes [changes to gene function without changing DNA]; enhanced cell migration, invasion, and…†more. Dr. Panis and other researchers at the Forum . . .
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