Gateway on Pesticide Hazards and Safe Pest Management
Trifluralin
Updated February 2019
General Information
- Product Names:
- Chemical Class: Dinitroaniline compound herbicide
- Uses: Annual grasses and broadleaf weeds on a variety of food crops and non-food uses, including residential use site
- Alternatives: Organic agriculture, Least toxic-weed managment
- Beyond Pesticides rating: Toxic
Health and Environmental Effects
- Cancer: Yes (66, 67, 68, 69)
- Endocrine Disruption: Probable (5, 36)
- Reproductive Effects: Yes (8)
- Neurotoxicity: Not documented
- Kidney/Liver Damage: Yes (4)
- Sensitizer/ Irritant: Yes (8)
- Birth/Developmental: Not documented
- Detected in Groundwater: Yes (37)
- Potential Leacher: Not documented
- Toxic to Birds: Not documented
- Toxic to Fish/Aquatic Organisms: Yes (8)
- Toxic to Bees: Not documented
Residential Uses as Found in the ManageSafe™ Database
Additional Information
- Supporting information:
- Extoxnet Trifluralin Factsheet (Extension Toxicology Network)
- PAN Pesticides Database:Trifluralin (Pesticide Action Network)
- Scorecard Trifluralin Factsheet (The Pollution Information Site)
- FAN Trifluralin Factsheet (Fluoride Action Network)
- Studies:
- Agricultural exposures and gastric cancer risk in Hispanic farm workers in California. Mills, P.K., and Yang, R.C. 2007. Environ Res 104(2):282-289.
- Assessment of genetic effects and pesticide exposure of farmers in NW Greece. Moshou, H., Karakitsou, A., Yfanti, F., Hela, D., Vlastos, D., Paschalidou, A.K., Kassomenos, P. and Petrou, I., 2020. Environmental Research, p.109558.
- Cancer incidence among pesticide applicators exposed to trifluralin in the Agricultural Health Study. . Kang, D. et al., 2008. Environmental research, 107(2), pp.271-276.
- Human exposure and risk assessment to airborne pesticides in a rural French community.. Coscollà C, López A, Yahyaoui A, Colin P, et al. 2017. Sci Total Environ. 584-585:856-868
- In vitro genotoxicity assessment of dinitroaniline herbicides pendimethalin and trifluralin.. Kılıç, Z.S., Aydın, S., Bucurgat, Ü.Ü. and Başaran, N., 2018. Food and chemical toxicology, 113, pp.90-98.
- A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides. Paul, K.C., Krolewski, R.C., Lucumi Moreno, E., Blank, J., Holton, K.M., Ahfeldt, T., Furlong, M., Yu, Y., Cockburn, M., Thompson, L.K. and Kreymerman, A., 2023. Nature Communications, 14(1), p.2803.
- Pesticide use and incident Parkinson’s disease in a cohort of farmers and their spouses. Shrestha, S. et al. (2020) Pesticide use and incident parkinson’s disease in a cohort of farmers and their spouses, Environmental research. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822498/.
- Pesticides and prostate cancer incidence and mortality: An environment-wide association study. Soerensen, S. et al. (2024) Pesticides and prostate cancer incidence and mortality: An environment-wide association study, Cancer. Available at: https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.35572.
- Pesticide exposure and risk of cardiovascular disease: A systematic review. Zago, A. M., Faria, N. M. X., Fávero, J. L., Meucci, R. D., Woskie, S., & Fassa, A. G. (2022). Pesticide exposure and risk of cardiovascular disease: A systematic review. Global public health, 17(12), 3944–3966. https://doi.org/10.1080/17441692.2020.1808693