Daily News Archive
From December 23, 2004
Linked to Inflammatory Disease
The study appears in the second issue for December 2004 of the American Thoracic Society's peer-reviewed American Journal of Respiratory and Critical Care Medicine. The investigators, Anthony Newman Taylor and Paul Cullinan, studied 706 newly diagnosed sarcoidosis patients, together with an equal number of age, race, and sex-matched control subjects. The goal of the study was to understand what environmental and occupational exposures were associated with the disease.
strong positive associations between the disease sarcoidosis and occupational
exposure to insecticides in both agricultural and industrial settings,
as well as with occupational exposure to "moldy" and "musty"
environments. The authors noted that one of the strongest positive associations
in the study was for occupational exposure to insecticides at any time
before participation in the study, particularly in the 3 years preceding
diagnosis. They point out that agricultural workers encounter high levels
of exposure to chemicals and aerosolized particulates, including grains,
bedding materials, silicates, animal proteins, insect proteins, fungi,
bacteria, mycotoxins, and endotoxins.
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