(Beyond Pesticides, April 17, 2025) A literature review in Reproductive Sciences finds glyphosate (GLY) and glyphosate-based herbicides (GBH) impact women’s reproductive health, adding to the long list of documented harm from this widely used weed killer. The authors note, “Considering the widespread use of GLY, the controversy regarding its endocrine-disrupting potential and reproductive toxicity, and the innumerable lawsuits filed against Bayer and Monsanto by consumers for morbidities related to Roundup™ exposure, the purpose of this review is to summarize the current literature on the potential adverse effects of GLY and GBHs on the female reproductive tract and discuss possible clinical implications on reproductive health outcomes, including polycystic ovarian syndrome (PCOS), endometriosis, and female fertility.”  Glyphosate and aminomethylphosphonic acid (AMPA), the primary metabolite (breakdown product) of GLY, are found throughout the environment in soil and water, as well as in samples of blood, urine, seminal plasma, and breast milk. Studies have detected residues in farmworkers, as well as “in the urine of 60–80% of the general public in the USA, including pregnant women and children.” (See studies here, here, and here.) The ubiquitous use of GLY and GBH, and subsequent persistence, threatens the health and well-being of all.  Previous studies have […]

(Beyond Pesticides, April 11, 2025) In a new report by Save our Seeds/Foundation on Future Farming, a consortium of EU-based scientists and bioethicists raise concerns about the implications and threats of generative artificial intelligence (GAI) for genetic engineering. Artificial intelligence will impact all aspects of society, including the acceleration of genetic editing tools that may lead to increased risks of harmful traits/genetic data being incorporated into products on the global marketplace. Organic farmers, conservationists, and public health professionals who collaborate with Beyond Pesticides grow increasingly concerned about the long-term impacts of deregulation and ongoing federal funding freezes and firings on needed regulatory oversight of the tech sector, including AI. Review of Save our Seeds Report So, what is artificial intelligence (AI)? AI is a broad field that focuses on building machines and systems that can think, learn, and solve problems—incorporating elements of human behavior. It powers things like voice assistants, self-driving cars, and recommendation systems on apps like Netflix or Spotify. In short, AI is designed to understand information, make decisions, and complete tasks intelligently. Generative AI, however, is an extension of AI focused on creativity. The main goal is to generate new content—whether in writing, photography, video, music, or […]

(Beyond Pesticides, March 27, 2025) In Ecotoxicology, results of a study on Nile tilapia (Oreochromis niloticus) exposed to florpyrauxifen-benzyl (FPX) suggest the new herbicide causes oxidative stress (imbalances affecting the body’s detoxification abilities that lead to cell and tissue damage), with specific genotoxic (damage to genetic material) and hepatotoxic (damage to the liver) effects on nontarget species. The authors state: “According to the available literature, no data exist on the toxicity of FPX in fish. Therefore, this study aims to investigate, for the first time, the potential toxicity and associated mechanistic effects of the pyridine-carboxylic acid herbicide (FPX) on the non-target species, Nile tilapia.” According to the Wisconsin Department of Natural Resources, “Florpyrauxifen-benzyl is a systemic herbicide (i.e., it moves throughout the plant tissue). It is a WSSA Group 4 herbicide, meaning that the mechanism of action is by mimicking the plant growth hormone auxin and causing excessive elongation of plant cells, ultimately killing the plant.” The researchers, from Menoufia University, the Agricultural Research Center, and Cairo University in Egypt, focus on FPX as it is the active ingredient in Divixton 2.5% EC, a newly released herbicide used in rice fields and applied directly to freshwater aquatic bodies for emergent […]

(Beyond Pesticides, March 21, 2025) Sin maíz, no hay país – “Without corn, there is no country” (Mexican saying) In the face of U.S. efforts to require Mexico, under a trade agreement, to import genetically engineered corn, last week the Mexican legislature approved a constitutional amendment identifying native corn as “an element of national identity” and banning the planting of GE seeds. This brings to a head a clash over issues of food sovereignty and security, genetic integrity, health protection, and environmental safety. In 2020, the Mexican government committed to phasing out the importation of genetically engineered (GE) corn by 2024. Mexico had also planned to ban by April 1, 2025, the weed killer glyphosate, integral to GE corn production—but recently delayed its decision. These actions by Mexico triggered vigorous pushback by the U.S., resulting in the formation of a panel under the U.S.-Mexico-Canada Agreement (USMCA) to decide which country was in the right. The USMCA, negotiated in 2018 during President Trump’s first term, replaced the North American Free Trade Agreement. Under USMCA, parties can adopt measures to protect human animal or plant life or health. However, in December 2024, the USMCA panel ruled in favor of the U.S., rejecting […]

(Beyond Pesticides, March 4, 2025) A study in GeoHealth of pediatric cancers in Nebraska links exposure to agricultural mixtures with the occurrence of these diseases. The authors find statistically significant positive associations between pesticide usage rates and children with cancer, specifically brain and central nervous system (CNS) cancers and leukemia. “Our study is the first to estimate the effect of an agrichemical mixture on the pediatric cancer rate in Nebraska,” the study authors share. “One significant advantage of our study is that we identified the pesticide consistently applied over 22 years in Nebraska counties and then estimated the overall mixture effect of these pesticides on pediatric cancer.” The elevated effect of pesticide mixtures, a reality that is not evaluated in the U.S. Environmental Protection Agency’s (EPA) pesticide registration program, was reported in Oecologia (2008), documenting harm to amphibian populations even if the concentration of the individual chemicals is within limits considered acceptable. (See additional coverage here.) There is a wide body of science highlighting the disproportionate risk of adverse health effects in children with pesticide exposure. Their small size and developing organ systems, propensity to crawl and play near the ground, tendency for frequent hand-to-mouth motion, and greater intake of […]

(Beyond Pesticides, December 23, 2024) As the U.S. Fish and Wildlife Services (FWS) proposes to list the Monarch butterfly as a threatened species under the Endangered Species Act, a look at the factors contributing to the butterfly’s catastrophic decline includes a stunning failure of the U.S. Environmental Protection Agency’s (EPA) regulation of pesticides to protect biodiversity and the ecosystems necessary to its survival. While there are many factors affecting the survival of Monarchs, EPA’s Office of Pesticide Programs (OPP) has allowed pesticide use to continue unabated, with only rhetorical attention to the problem. Meanwhile, the science shows a range of pesticide effects associated with insecticides and herbicides. A study published in PLOS One in June identifies insecticides as the primary driver in butterfly’s decline, as EPA points, almost exclusively to herbicide use and the destruction of Monarchs’ food source, milkweed habitat. While two or several factors can be true at the same time, EPA has failed to consider the confluence of factors, including the impacts of climate, as rising temperatures are exacerbated by the production and use of petrochemical pesticides. FWS is stepping in at a critical time with looming biodiversity collapse and in the absence of EPA taking the reins […]

(Beyond Pesticides, December 18, 2024) A bombshell investigation conducted by Canada’s National Observer finds that Bayer, which acquired the Monsanto chemical company in 2018, colluded with environmental and public health regulators in Canada to obstruct a proposed neonicotinoid insecticide ban originally introduced in 2018. Advocates were stunned back in 2021 when Canada’s Pest Management Regulatory Agency (PMRA)—the Canadian counterpart to the U.S. Environmental Protection Agency (EPA)—reversed its decision to phase out imidacloprid, clothianidin, and thiamethoxam by 2023. The weaponization of scientific institutions and regulatory processes is commonplace in the U.S. context, with U.S. Right to Know publishing a report earlier this year on the corrupting impact of pesticide manufacturers at the Entomological Society of America 2023 annual meeting. (See Daily News here.) There are numerous Office of Inspector General (OIG) reports signaling EPA corruption and failures, including persisting industry influence in the cancer risk assessment process, inadequate leadership in addressing community harms of a former creosote-treated wood preservative plant turned Superfund site in Pensacola, Florida, and failure to protect the public from endocrine-disrupting chemicals, to name several examples. In a recent press release, the David Suzuki Foundation, alongside numerous medical, legal, and civil society organizations, is calling on Health Canada […]

(Beyond Pesticides, December 13, 2024) In October, the U.S. Environmental Protection Agency (EPA) approved the registration applications of BASF Corporation and Mitsui Chemicals Crop & Life Solutions, Inc. for the use of different formulations of the L-isomer of glufosinate (also known as “L-glufosinate” and “glufosinate-P”) as new active herbicidal ingredients. This decision marks one of the first times that EPA has employed its new Herbicide  Strategy Framework to determine the level of mitigation necessary to protect listed species and critical habitat under the Endangered Species Act (ESA). Glufosinate is an organophosphate, with known neurotoxic, reproductive/developmental effects, toxic to aquatic life, and mobile in soils (see Beyond Pesticides Gateway). Scientists have found that formulated glufosinate is generally more toxic to aquatic and terrestrial animals than the technical grade active ingredient. Manufacturers are introducing newer glufosinate products as alternatives for glyphosate-based herbicides, like Bayer/Monsanto’s ‘Roundup’ and dicamba. The Center for Biological Diversity notes in comments submitted to EPA on this decision, “L-glufosinate has the potential to be used on tens of millions acres of land every year given the crops EPA has proposed to register it on. The scale of potential use is far above most new active ingredients.” This first significant application […]

(Beyond Pesticides, November 13, 2024) A study in Chemosphere, conducted by researchers from the Institute of Biochemistry and Molecular Biology in Germany, reveals the varied lethal and sublethal effects of different glyphosate mixtures through tests on the South African clawed frog, Xenopus laevis (X. laevis). After exposing embryos to four glyphosate formulations, mortality, morphological defects, altered heartbeat rate, and impaired heart-specific gene expression are observed. Glyphosate, an herbicide and popular weed killer in many Roundup® products, is one of the most commonly detected pesticides in waterbodies worldwide, threatening aquatic organisms and overall biodiversity. This study investigates the effects of Glyphosat TF, Durano TF, Helosate 450 TF, and Kyleo, four formulations containing glyphosate, as compared to the effects of pure glyphosate on embryonic development in amphibians. The formulations consist of varying concentrations of the active ingredient glyphosate, as well as other active and inert ingredients. The authors share that, “Glyphosat TF contains 34% glyphosate and 10–20% d-glucopyranose, while Durano contains 39–44% glyphosate and 1–5% N–N-dimethyl-C12-C14-(even numbered)-alkyl-1-amines. In Helosate most of the ingredients are listed – 50–70% glyphosate, 1–10% isopropylamine, 1–3% lauryl dimethyl betaine, 0.25–1% dodecyl dimethylamine. Kyleo only lists the active ingredients glyphosate (27.9%) and 2,4-D (32%).” 2-cell stage embryos (early […]

(Beyond Pesticides, September 30, 2024) Public Comment Period on Issues of Organic Integrity Closes Today. Farming is a notoriously risky enterprise, and organic farming presents further challenges along with its multiple benefits. Generally, organic has made great strides over the last several years and is strongly supported by American consumers, findings in the latest U.S. Department of Agriculture (USDA) Census. Even late this year, there is the prospect of several more important changes that will improve the organic certification process and some issues that will take more policy changes to resolve in the future. As a part of this process to ensure the integrity of the USDA organic label and the permitted production practices, Beyond Pesticides urges that the public submit comments TODAY (the last day for the comment period) on issues currently before the National Organic Standards Board (NOSB). See two sets of comments on key issues that can be submitted with one click each. Click here on issues related to use of plastic, nonorganic ingredients in processed food, and seeds and plant starts. Click here on inert ingredients, contaminants in compost, and drugs in livestock production. U.S. agriculture overall has remained fairly robust between the USDA Census in […]

Image: EneasMx, CC-BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0/>, via Wikimedia Commons (Beyond Pesticides, July 19, 2024) Former mayor of Mexico City and climate scientist Claudia Sheinbaum, PhD was elected President of Mexico on June 2, making her the first female and Jewish citizen to hold the highest political office in the nation. She will be inaugurated on October 1, 2024. Dr. Sheinbaum’s ascension to the presidency comes at a time of increasing pressure from the United States government to acquiesce to its demands to open agricultural markets to genetically engineered (GE) crops (particularly corn) and the use of the carcinogenic weed killer glyphosate. With the formal review of the United States-Mexico-Canada Agreement (USMCA) approaching in 2026, Mexico will soon decide under Dr. Sheinbaum’s leadership whether it will be an international stalwart against the unfettered spread of GE corn amidst pressure from the U.S. Trade Representative and as industry continues to enable the cascading crises of the climate emergency, public health crisis, and biodiversity collapse. With new administrations in the United Kingdom and France, and the upcoming election in the U.S., how governments around the world, independently and collectively, choose to seriously confront or soft-pedal the existential environmental crises will determine the livability of […]

(Beyond Pesticides, June 10, 2024) Expanding the planting of genetically engineered crops is the major focus of “The Coordinated Framework for the Regulation of Biotechnology – Plan for Regulatory Reform under the Coordinated Framework for the Regulation of Biotechnology” (Framework), released in May by three federal agencies. In its Framework, the U.S. Department of Agriculture (USDA), the Food and Drug Administration (FDA) and the U.S. Environmental Protection Agency (EPA) use the words “exempt” or “exemption” in reference to federal safety regulations 21 times. Then, another 21 times the agencies identify their efforts to “streamline” the process for bringing genetically engineered “plant-incorporated protectants” (PIPs) to market. Without including the word “resistance” even once, the Framework advances the interests of the biotech and allied industries, ignoring the serious scientific issues regarding health and environmental effects and the economic failure for farmers facing crop loss. Meanwhile, the issue of resistance is not new to EPA, which has for years acknowledged the resistance problem despite allowing continued weed resistance to weed killers used with herbicide-tolerant crops and insect resistance to the pesticides incorporated into plants.   >> Tell USDA, FDA, and EPA to replace agricultural provisions in the Framework with policies that discourage GE crops […]

(Beyond Pesticides, May 21, 2024) In a first-of-its kind series of biomonitoring studies published in Agrochemicals, researchers identified the presence of the herbicides dicamba and 2,4-D in all pregnant participants from both cohorts in 2010-2012 and 2020-2022. The findings from this research are not surprising given the explosion of toxic petrochemical pesticides in the Midwest region of the United States. “The overall level of dicamba use (kilograms applied in one hundred thousands) in the U.S. has increased for soybeans since 2015 and slightly increased for cotton and corn,” the authors report, based on U.S. Department of Agriculture National Agriculture Statistics Service surveys. “The overall level of 2,4-D use (kilograms applied in one hundred thousands) in the U.S. was highest in 2010 for wheat, soybeans, and corn. The amount of 2,4-D applied increased the most for soybeans and corn from 2010 to 2020.” The researchers focused on the states of Illinois, Indiana, and Ohio, given the increase in dicamba and 2,4-D during the study period for both cohorts (2010-2022). The researchers are based at Indiana University School of Medicine in the Department of Biostatistics and Health Data Science and Department of Obstetrics and Gynecology, Quebec Toxicology Center within the Institut national […]

(Beyond Pesticides, March 26, 2024) The authors of a case study in Canale D’Aiedda, Taranto, Italy, published in Scientific Reports, conclude that, “[T]he results of monitoring and modeling activities revealed a chronic risk associated with the presence of Cu [copper] from November to April in several river reaches and acute risk associated to the presence of glyphosate in several reaches mainly in the wet season.”  According to the authors, “The most important factor influencing the chronic risk for Cu were the combination of two factors: the high surface runoff and the Cu applications. The most important factor influencing the glyphosate peaks of concentration is the streamflow.” The authors of the study measure the flow of pesticide concentrations through the soil and water assessment tool (SWAT). The ecotoxicological data was collected at two stations in Germany that flow into Italy, within the Canale d’Aiedda basin. The streamflow was monitored between August 2017 and December 2019. Out of hundreds of pesticides and six metabolities investigated in this study, “only traces of copper and glyphosate were found.” The authors continue, “The banks and the bed of the river system are almost all covered by concrete. The hydrological regime is natural and intermittent in […]

(Beyond Pesticides, March 20, 2024) A report by CBAN unpacks the ecosystem and wildlife health impacts of genetically engineered (GE) corn in the context of Mexico’s 2023 decision to stop its importation into the country. The phase out of genetically modified (GM) corn imports into Mexico was immediately challenged by the U.S. and Canadian governments as a trade violation under the 2020 U.S.-Mexico-Canada Agreement (USMCA), which replaced the North American Free Trade Agreement (NAFTA) as the primary vehicle for North American trade policy. In August 2023, the U.S. Trade Representative set up a dispute settlement panel under USMCA to stop Mexico from going forward with its ban. There has been no public update from the Office of the U.S. Trade Representative as of this writing. The CBAN report highlights the scientific rationale underpinning Mexico’s decision to “safeguard the integrity of native corn from GM contamination and to protect human health” with this ban. In 2020, Mexico announced a four-year phase-out of the weed killer glyphosate, which along with other petrochemical herbicides is integral to GM corn production. When Mexico’s Minister of the Environment announced the phase-out, he said it is part of an effort to transform the country’s food system […]

(Beyond Pesticides, February 28, 2024) The U.S. Environmental Protection Agency (EPA) is putting on hold its Vulnerable Species Project (VSP) after vociferous comments from the petrochemical pesticide industry to instead, “create a narrow, tailored policy rather than a sweeping, burdensome one,” according to a recent op-ed in the Wall Street Journal. Upon heavy pushback from the petrochemical pesticide industry and agribusiness, EPA is hosting a variety of workshops and openings for the public to provide feedback not just on VSP, but the Endangered Species Act (ESA) Workplan the Biden Administration originally introduced in 2021 in its entirety. Advocates are calling for the strengthening of pesticide regulation given the impending decisions that may shape the fate of ESA-FIFRA (Federal Insecticide, Fungicide, and Rodenticide Act) compliance for years to come. As EPA continues through its pesticide registration program to advance continued dependency on pesticides through its interpretation of FIFRA, despite the availability of nontoxic alternatives, endangered species extinction and biodiversity collapse has never been a high priority. While EPA has initiated efforts to address a significant backlog of pesticide evaluations, Civil Eats has reported that the agency faces a task so extensive that it may require several additional decades to fully catch up. EPA officials stated, “Even if EPA completed […]

(Beyond Pesticides, February 13, 2024) Last week, the United States District Court for the District of Arizona struck down the U.S. Environmental Protection Agency’s (EPA) 2021 approval of three dicamba-based herbicides. This is the second lawsuit since 2020 to call out EPA’s violation to both the Endangered Species Act (ESA) and the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) to authorize the use of over-the-top (OTT) dicamba-based herbicide products from Bayer and other petrochemical pesticide companies. This rejection of dicamba-based herbicides fuels advocates’ push for stronger regulatory actions by EPA for all petrochemical pesticides and their push for the more widespread adoption of organic practices that do not use these chemicals. The case was filed by Center for Food Safety (CFS), Center for Biological Diversity, National Family Farm Coalition, and Pesticide Action Network North America. Beyond Pesticides has covered the dicamba tragedy for years, including the EPA Office of the Inspector General’s critical 2021 report, EPA Deviated from its Typical Procedures in Its 2018 Dicamba Pesticide Registration Decision. The report identifies EPA’s abandonment of science and assault on agency integrity. In addition to citing adverse impact on nontarget crops and the environment, the Court zeroes in on EPA’s failure to adequately manage […]

(Beyond Pesticides, February 1, 2024) A study published in Science of The Total Environment finds an insecticide ban would be economically beneficial in preventing Parkinson’s disease (PD). Despite differing pesticide exposure scenarios, PD risk lowers without pesticide exposure, especially insecticides that elicit neurotoxicity. In fact, a study published in 2023 notes high exposure to household pesticides, which are primarily insecticides, increases the risk of developing Parkinson’s disease (PD) two-fold. There is a multitude of epidemiologic research on Parkinson’s disease demonstrating several risk factors, including specific genetic mutations and external/environmental triggers (e.g., pesticide use, pollutant exposure, etc.). However, several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the widespread commercialized use of household pesticides among the general population, few epidemiologic studies examine the influence household pesticides, mainly insecticides or disinfectants, have on the risk of PD. Additionally, many studies demonstrate the association between PD onset and occupational (work-related) pesticide exposure patterns. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans […]

(Beyond Pesticides, October 30, 2023) TAKE ACTION. It is said that the definition of insanity is doing the same thing over and over again and expecting a different result. And so it goes with the U.S. Environmental Protection Agency’s (EPA) proposal to register a new genetically engineered pesticide for the Colorado Potato Beetle (CPB); this time with a pesticide that has not been fully evaluated for its adverse effects to people and the environment. [Submit a public comment before comment period ends today, October 30, 2023.] Chemical-intensive agriculture has failed to control CPB since resistance to DDT was identified in 1952 and has continued with every family of pesticides since then. CPB has been dubbed the billion-dollar-bug because of the investment in failed attempts of chemical manufacturers to control the insect, the profits generated by chemical companies despite this failure, and the resulting losses for chemical-intensive farmers—not to mention government expenditures for the registration of chemicals that have short efficacy, pollution costs associated with chemical production and use, and lost ecosystem services. But, EPA is at it again, registering a new novel pesticide active ingredient, Ledprona, which raises the stakes on potential harm. The only winners in this ongoing failure […]

(Beyond Pesticides, October 27, 2023) In a typical move, EPA proposes to greenlight a type of genetic engineering to solve a problem created by the industrial paradigm for pest control, i.e. vast acreages of monoculture treated with millions of tons of toxic pesticides leading to rapid resistance among crop pests. In this case EPA wants to approve using a nucleic acid—double-stranded RNA (dsRNA)–called “interfering RNA,” or RNAi—to silence a gene crucial to the survival of the Colorado Potato Beetle (CPB), the scourge of potato farmers around the world. But EPA has skipped over important steps in its decision-making process and rushed to judgment. Like chemical pesticides, genetically-based pesticides are regulated under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). In 2020, Massachusetts-based GreenLight Biosciences applied for registration of its RNAi active ingredient, Ledprona, and its end-use product, Calantha. The company executive heading the effort is an alumnus of Monsanto and several other major chemical companies. Last May EPA granted GreenLight an Experimental Use Permit (EUP) authorizing field studies in states that produce tons of potatoes. A mere five months later, EPA announced its decision to approve the registration based almost entirely on incomplete EUP data and giving the public very […]

(Beyond Pesticides, September 7, 2023) During Organic Month, the importance of organic practices is brought into sharp focus by a study published in July in Environmental Health Perspectives, which emphasizes the importance of an organic diet and location to residues of pesticides in the body. The study finds urinary levels of the weed killer glyphosate significantly decrease through an organic diet for pregnant individuals living further than 0.5km (~1640ft) from an agricultural field. However, the study finds that adopting an organic diet among pregnant individuals living closer than 0.5km to an agricultural area does not significantly decrease glyphosate levels, indicating alternative sources of contamination outside of diet. Although past studies prove time and time again that an organic diet can reduce the levels of pesticides in the body, far too few studies investigate how the intervention of the organic diet can alter glyphosate levels among pregnant individuals living near or far from agricultural fields on which the herbicide is used. Furthermore, pesticides’ presence in the body affects human health, especially during vulnerable life stages like childhood, puberty, pregnancy, and old age. The study raises the complexity of fully tracking multiple exposures to glyphosate and other pesticides and the need for […]

(Beyond Pesticides, July 28, 2023) A study published in Science of the Total Environment finds glyphosate can adversely impact sensory and cognitive processes in bumblebees (Bombus terrestris). Glyphosate exposure impairs bees’ learning of aversive stimuli like electric shocks paired with specific color discrimination. Additionally, the pesticide reduces attraction to UV (ultraviolet) light, specifically the color blue, and temporarily impacts locomotion and phototaxis (movement in response to light). These impairments to sensory and cognitive processes render foraging difficult for these glyphosate-exposed pollinators and vulnerable to unavoidable predators. The study highlights that symptoms of widespread chemical exposure may reduce foraging efficiency and adversely affect ecosystems, especially those dependent on insect pollinators.  Pollinator decline directly affects the environment, society, and the economy. Without pollinators, many plant species, both agricultural and nonagricultural, will decline or cease to exist as U.S. pollinator declines, particularly among native wild bees, limit crop yields. In turn, the economy will take a hit, since much of the economy (65%) depends upon the strength of the agricultural sector. As the science shows, pesticides are one of the most significant stressors for pollinators. In a world where habitat loss and fragmentation show no sign of abating, scientists have concluded that the globe cannot afford to continue […]

(Beyond Pesticides, July 11, 2023) A study published in Parkinsonism & Related Disorders finds high exposure to household pesticides increases the risk of developing Parkinson’s disease (PD) two-fold. There is a multitude of epidemiologic research on Parkinson’s disease demonstrating several risk factors, including specific genetic mutations and external/environmental triggers (i.e., pesticide use, pollutant exposure, etc.). However, several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Past studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the widespread commercialized use of household pesticides among the general population, few epidemiologic studies examine the influence household pesticides have on the risk of PD, although many studies demonstrate the association between PD onset via occupational (work-related) pesticide exposure patterns. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. Alzheimer’s ranks first. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and […]