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Beyond Pesticides Rating: Toxic

Sulfluramid was registered March 23, 1989 for indoor, nonfood use in bait stations on roaches and ants (U.S. EPA, 1989). It kills insects by disrupting energy metabolism (Cox, 1997). It is the active ingredient in Firstline ™ GT plus Termite Bait Station. 

Acute Toxicity

Sulfluramid is expected to be of low oral, dermal, and inhalation toxicity, and to be practically non-irritating to the skin and eyes.  Ingestion can produce symptoms such as diarrhea and abdominogenital staining (MSDS, 1998). The oral LD50 for rats is 500 mg/kg; the dermal toxicity for rabbits is LD50 >2000 mg/kg (U.S. EPA, 1989). 

Chronic Toxicity

The EPA has reported that, in laboratory animals, multiple exposures to relatively low levels of sulfluramid can cause adverse reproductive and developmental effects (Cox, 1997). The carcinogenicity status is not listed. Feeding studies in dogs suggested that ingestion of high doses for long periods of time might arrest spermatogenesis (MSDS, 1998). 

Environmental Fate

Sulfluramid is considered unlikely to enter groundwater (MSDS, 1998). 

Effects on Wildlife

Sulfluramid is highly toxic to birds and toxic to aquatic animals, with rainbow trout killed by concentrations of 2 ppm (Cox, 1997) 


Cox, C. 1997. "Subterranean Termites, Part 2." Journal of Pesticide Reform 17(2):21.  

Material Safety Data Sheet (MSDS): Firstline GT plus Termite Bait Station. 1998. FMC. Philadelphia, PA. 

U.S. EPA. 1989. Sulfluramid (GX-071) EPA Pesticide Fact Sheet 3/89. Office of Pesticide Programs. March. Washington, DC.