.Pesticide Gateway Index

.About the Gateway

.Eating with a Conscience

.Home

Gateway on Pesticide Hazards and Safe Pest Management
Read about the Gateway

Fipronil

General Information

• Beyond Pesticides Fipronil ChemWatch Factsheet
• Fipronil product names
• Chemical Class:Phenyl pyrazole insecticide
• Uses and Alternatives: Residential baits and gels, Agriculture, Golf courses
• Beyond Pesticides rating: Toxic

Health Effects

• EPA Acute Toxicity Class: II (moderately toxic)
• Cancer: Possible (10)
• Endocrine Disruption: Yes (7)
• Reproductive Effects: Yes (7)
• Neurotoxicity: Yes (7)
• Kidney/ Liver Damage:Yes (7)
• Sensitizer/ Irritant: Yes (7)
• Birth/ Developmental Defects: Not documented

Environmental Effects

• Detected in Groundwater: Not documented
• Detected in Streams: Not documented
• Potential Leacher: Not documented
• Toxic to Birds: Yes (7, 27)
• Toxic to Fish/ Aquatic Organisms: Yes (7, 27)
• Toxic to Bees: Yes (7, 27)
• Toxic to Mammals: Not documented
• Long-Range Transport: Not documented

Additional Information

• Regulatory Information:
  • Not yet reviewed
• Supporting information:
  • Daily News Blog entries (Beyond Pesticides)
  • NCAP Fipronil Factsheet (Northwest Coalition for Alternatives to Pesticides)
  • NPIC Fipronil Factsheet (National Pesticide Information Center)
  • PAN Pesticides Database:Fipronil (Pesticide Action Network)
  • PAN-UK Fipronil Factsheet (Pesticide Action Network UK)
  • CHEJ Fipronil Factsheet (Children's Health Environmental Coalition)
• Key Studies:
  • Fipronil-induced disruption of thyroid function in rats is mediated by increased total and free thyroxine clearances concomitantly to increased activity of hepatic enzymes. Leghait J, et al. 2009. Toxicology
  • Reproductive adverse effects of fipronil in Wistar rats. Ohi et al. 2004. Toxicology Letters
  • Human exposure to fipronil from dogs treated with frontline. Jennings, K.A. 2002. Vet Hum Toxicol