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Petrochemical Pesticides and Fertilizers Linked to “Shocking” Health and Environmental Crises

Tuesday, April 25th, 2023

Today, Beyond Pesticides released a special issue, Transformative Change: Informed by Science, Policy, and Action of its journal, Pesticides and You, with a compendium of “shocking scientific findings that compel us to act in our communities, states, and as a nation and world community.” The 168-page issue documents the last year of scientific, peer-reviewed articles, policy deficiencies, and action for change that intersect not only with petrochemical pesticides and fertilizers, but with existential health crises, biodiversity collapse, and the climate emergency.

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Protect Bees, Trees, You and Me This Earth Day 2023

Thursday, April 20th, 2023

(Beyond Pesticides, April 20, 2023) This Earth Day (Saturday, April 22, 2023), Beyond Pesticides urges individuals to spread awareness of the toxic pesticides that poison people and the environment and the safe alternatives that are available to safeguard communities and the surrounding environment. On Earth Day, reflecting on the beauty and wonder of the natural world highlights the importance of restoration and preservation to maintain the planet’s intricate web of life. However, the natural world on which life depends is under dire threat as the dependence on toxic chemicals (e.g., pesticides) enables ongoing environmental contamination. Mechanized and industrial human activity perpetuates ongoing toxic chemical contamination, resulting in massive die-offs of beneficial organisms, increased rates of autoimmune diseases, endocrine disrupting and transgenerational chemical effects, and widespread pollution of our air and waterways. Beyond Pesticides, has the tools needed to increase environmental awareness in your community. Therefore, this Earth Day, Beyond Pesticides continues to advocate for the adoption of organic practices and policies that alleviate threats to ecosystems and enhance biodiversity. Michigan State University professor Thomas Dietz, Ph.D. highlights, “Continuing the successes of environmentalism—an integration of science, a concern with human well-being and justice, and a recognition of the need to consider […]

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Two Pesticides Threaten Dozens of Endangered Species, EPA Proposes Failed Risk Mitigation Measures

Friday, April 14th, 2023

(Beyond Pesticides, April 14, 2023) In March, scientists at the National Marine Fisheries Service (NMFS) issued a draft Biological Opinion (BiOp) stating that carbaryl and methomyl — two commonly used carbamate insecticides — cause significant harm to dozens of already-endangered fish species in the Pacific Northwest’s Columbia, Willamette, and Snake rivers. The BiOp indicates that these toxic compounds, in wide use on orchards and field vegetables throughout the Willamette Valley, the Columbia River Gorge, and southeastern Washington, will likely threaten scores of species on the Endangered Species list: 37 species at risk from carbaryl and 30 from methomyl. In addition, the BiOp says, “both are likely to harm or destroy many areas designated as critical habitat for endangered species.” The mitigation measures proposed by NMFS and the U.S. Environmental Protection Agency (EPA), in light of this BiOp, are likely to be inadequate to the problem, given that both compounds can drift through air and/or migrate into groundwater and generate toxic runoff. These two neurotoxic insecticides, carbaryl and methomyl, are very toxic to bees, birds, fish, and other aquatic organisms. In addition, carbaryl is a likely human carcinogen and an endocrine disruptor, and has harmful impacts on multiple bodily systems. Methomyl is […]

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Pesticides and the Climate Crisis: Bumble Bee Behavior Thwarted by Temperature and Chemical Exposure

Thursday, April 6th, 2023

(Beyond Pesticides, April 6, 2023) A study published in Global Change Biology adds to research demonstrating that climate change can exacerbate the adverse impacts of pesticide exposure on managed and wild bees. Temperature can alter the sublethal effect pesticides, particularly the neonicotinoid (neonic) imidacloprid and the sulfoximine sulfoxaflor, have on bumble bee behavior tied to fitness and pollination services. Both an increase and decrease in temperature can cause diverging thermal responses in bumble bee behavior. However, increasing temperature bares more severe behavior abnormalities than cooler temperatures. The pervasiveness of pesticide exposure combined with climate change threatens global species biodiversity. As has been widely reported, pollinators (such as bees, monarch butterflies, and bats) are a bellwether for environmental stress as individuals and as colonies. Pesticides intensify pollinators’ vulnerability to health risks (such as pathogens and parasites), with pesticide-contaminated conditions limiting colony productivity, growth, and survival. Now more than ever, people are changing their sentiment toward sustainability, with two-thirds of consumers stating the importance of limiting climate change impacts and 88 percent supporting greater pollution reduction. The globe is currently going through the Holocene Extinction, Earth’s 6th mass extinction, with one million species of plants and animals at risk. With the increasing rate of biodiversity loss, advocates say it is essential for […]

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Mayan Beekeepers Implicating Bayer/Monsanto in Die-Off of 300,000+ Bees, Harming Their Livelihood

Wednesday, April 5th, 2023

(Beyond Pesticides, April 5, 2023) A collective of Mayan beekeepers (Colectivo de Comunidades Mayas) in Mexico are implicating chemical industry giant Bayer/Monsanto in a massive die-off of more than 300,000 bees among their combined apiaries. According to Mexico News Daily, the total value of losses represent a staggering $663,000 U.S. dollars (12 million pesos). The incident is the latest instance of the pesticide  and agrichemical industry setting up shop in a local community and wrecking the health of the local ecology. Mayan beekeepers explain that Bayer/Monsanto recently started operations on a ranch near Crucero OxĂĄ in the southern Mexican state of Campeche. A local businessman placed the 50 hectare ranch on loan to the company. Since that arrangement, the company has aerially sprayed row crops like corn and soy with undisclosed chemicals. “One of Bayer’s engineers or technicians allowed us to take samples from one of their crops after the bees started to die,” said beekeeper JosĂŠ Manuel Poot Chan, to the newspaper La Jornada Maya. “We are exhausting all possible legal instances, while members of the Welfare Ministry already came to offer humanitarian social aid to cover part of the damages.” Beekeepers suspect that the company is using the […]

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Implications for Human Health: Work-Related Pesticide Exposure Increases Sleep Disorder Risk

Tuesday, March 14th, 2023

(Beyond Pesticides, March 14, 2023) A study published in Environmental Research and Public Health finds occupational pesticide exposure increases the risk of sleep disorders among farmworkers and pesticide applicators. Specifically, many pesticides, like organophosphates (OPs), are detrimental to neurological function through inhibition of the enzyme acetylcholinesterase (AChE) responsible for ending a neurotransmission event after relaying the necessary information. Without an end to neurotransmission events, individuals experience a buildup of acetylcholine, resulting in convulsions, headaches, weakness, impacts on bodily senses, and other cognitive/mental changes. In addition to illnesses from chemical exposure, inadequate sleep has links to several chronic diseases like type 2 diabetes, cardiovascular disease, obesity, and depression. Therefore, given research links to sleep-related disorders and bodily functions, including endocrine, metabolic, neurological, and cognitive disorders, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The study notes, “The study’s findings can be used to create strategies for addressing mental health issues and promoting mental health and quality of life.” Researchers assess the sleep patterns among individuals living in southeast Spain, near the coast of Almeria, where chemical-intensive agriculture from greenhouses is prevalent. Of the 380 participants in the study, 189 were […]

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Prenatal Pesticide Exposure Threatens Children’s Language Development at 18 Months after Birth, Study Finds

Thursday, March 9th, 2023

(Beyond Pesticides, March 9, 2023) A study published in Environmental Research finds exposure to organophosphate (OP) compounds during pregnancy, or prenatal OP exposure can cause shortfalls in language development abilities at 18 months, stifling preschool-age language expression. Additionally, a timely and co-occurring study published in Environmental International confirms similar results, highlighting that chlorpyrifos (an organophosphate) impedes neurological and psychological development, including language communication and all motor skills of offspring at 12 and 18 months old. Prenatal development is one of the most vulnerable periods of exposure, as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. Given research links to pesticide exposure and neurological and cognitive development, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The Environmental Research authors note, “The etiology [cause] of language development is complex, and this work further highlights the importance of the prenatal environment as a mechanism of influence that are associated with deficits in early language acquisition and ability, which could signal increased behavioral problems and academic difficulties in later childhood that extend […]

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Pesticide Exposure and the Link to Irritable Bowel Syndrome (IBS)

Thursday, March 2nd, 2023

(Beyond Pesticides, March 2, 2023) Populations experiencing higher levels of environmental pollutant exposure, specifically pesticides, also experience a higher rate of irritable bowel syndrome (IBS), according to a study published in Environmental Toxicology and Pharmacology. IBS is a gastrointestinal disorder that causes abdominal pain or discomfort and changes in bowel behaviors. IBS affects 25 to 45 million individuals in the U.S., mostly female (two-thirds). Additionally, a quarter to half of all gastrointestinal-related visits are for IBS symptoms. Despite the unknown etiology of IBS, ample evidence demonstrates environmental contaminants, like pesticides, negatively affect the gut microbiota, causing a microorganism imbalance and resulting in inflammation associated with IBS. The gut, also known as the “second brain,” shares similar structural and chemical parallels to the brain. The microbiota in the gut plays a crucial role in lifelong digestion, immune and central nervous system regulation, as well as other bodily functions. Although studies show how chemical exposures affect overall human health, a growing body of peer-reviewed scientific literature is now questioning how these toxic chemicals influence gut health and the subsequent occurrence of diseases. The study notes, “These findings may help to understand the relationship between pesticide exposure and IBS; however, more epidemiological and experimental research is needed to understand […]

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Neonicotinoids Combined with Other Pesticides Elevate Hazards to Honey Bee

Wednesday, February 22nd, 2023

(Beyond Pesticides, February 22, 2023) Combining neonicotinoid insecticides with other commonly used pesticides can result in synergistic effects on honey bees, increasing toxicity more than any individual chemical could, according to research published in Scientific Reports earlier this month. The data highlight the grave inadequacy of the U.S. Environmental Protection Agency’s (EPA) process for evaluating pesticide risks. Under current regulations, EPA requires chemical manufacturers to submit data only on singular active ingredients. Yet, pesticide products may be packaged or ‘tank mixed’ with other, equally toxic pesticides without any obligation to determine the toxicity of the material that is actually being applied. Independent research is left to fill in these gaps, and the data increasingly shows that toxicity with pesticide mixtures amounts to a roll of the dice: sometimes combinations are less toxic, sometimes their toxicities are merely additive. But more often than not, pesticide mixtures result in synergistic effects that make the product significantly more toxic than either individual chemical alone. To understand how pesticide combinations are harming pollinators, scientists began with baseline data on the individual toxicity range  that common pesticides pose to honey bee colonies. Research was conducted on honey bees reared in the Stoneville Wildlife Management Area […]

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More Dramatic Insect Decline Confirms Inadequate Action on Pending Biodiversity Collapse

Thursday, February 16th, 2023

(Beyond Pesticides, February 15, 2023) Areas designated to protect insects fail to do so for over 75 percent of global species, according to a study, “Three-quarters of insect species are insufficiently represented by protected areas,” published in the online journal One Earth. Protected Areas (PAs) act as a safeguard for biodiversity. However, PAs in North America, Eastern Europe, Southeast Asia, and Australia do not meet the minimum coverage requirements to safeguard global insect species assessed in the study. PAs are discussed in the 2020 Nature article, “Area-based conservation in the twenty-first century,” in which the authors state that, in view of the global biodiversity crisis, national governments must do much more to increase protected areas with “coverage across different elements of biodiversity (ecoregions, 12,056 threatened species, ‘Key Biodiversity Areas’ and wilderness areas) and ecosystem services (productive fisheries, and carbon services on land and seas).” The authors write, citing the UN Convention on Biological Diversity (to which the United States is not a signatory), “To be more successful after 2020, area-based conservation must contribute more effectively to meeting global biodiversity goals—ranging from preventing extinctions to retaining the most-intact ecosystems—and must better collaborate with the many Indigenous peoples, community groups and private initiatives […]

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Local Authority to Restrict Pesticides Would Be Codified by Federal Reform Bill

Monday, February 13th, 2023

(Beyond Pesticides, February 13, 2023) As more and more communities across the country outlaw pesticides on their public land, parks, and playing fields, most states prohibit (or preempt) localities from restricting hazardous use on private property. As a result, pesticides used on landscapes—uses that can be replaced by organic management practices—result in chemical drift and runoff, putting the community in harms way and people involuntarily exposed. The Protect America’s Children from Toxic Pesticides Act of 2023 (PACTPA), S.269, includes a provision that grants communities under federal pesticide law (the Federal Insecticide, Fungicide, and Rodenticide Act—FIFRA) local authority to restrict pesticides on all property, public and private, within their jurisdiction. While the U.S. Supreme Court (in Wisconsin Public Intervenor v. Mortier) in 1991 found that FIFRA does not preempt local governments’ authority to restrict pesticide use in their town, cities, or counties, state governments have taken that authority away in 44 states at the behest of the pesticide lobby. Urge your Senators to co-sponsor PACTPA and reforms to the toxic core of FIFRA, including upholding the right of local governments to restrict pesticides. As local governments debate the hazards associated with pesticide use in their communities, many have decided to transition their […]

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Four Pesticides Restricted to Protect Salmon, Thousands of Other Endangered Species Imperiled

Friday, February 10th, 2023

(Beyond Pesticides, February 10, 2023) The U.S. Environmental Protection Agency (EPA) announced, on February 1, new measures to protect 28 endangered salmon species (including steelhead trout) from the use of four pesticides that threaten them and their critical habitats. Those compounds comprise three herbicides — metolachlor, bromoxynil, and prometryn, and one soil fumigant, 1,3-Dichloropropene. The protections, aimed at salmon populations in Washington, Oregon, and California, are meant to reduce impacts from pesticide runoff and spray drift, and to minimize potential “take.” (Under the Endangered Species Act (ESA), “take” means, essentially, the unintentional harming or killing of an individual of a protected species — in this case, harm or death from exposures to these toxic pesticide compounds.) Beyond Pesticides and other advocates have for years warned that multiple pesticides are threats to Northwest salmon and other species at risk. This EPA announcement is the second of two, recently, that offer slight redress to the agency’s historical failures to act (see more below). Indeed, advocates have engaged in multiple litigation efforts over the years to try to force EPA to take action; EarthJustice in 2001 noted some early instances. As Chemical and Engineering News says pointedly, “Environmental groups, which have been suing […]

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Pesticide Reform Bill Reintroduced in U.S. Senate, Advocates Call Changes Major But Not Systemic Ones Needed

Tuesday, February 7th, 2023

(Beyond Pesticides, February 7, 2023) U.S. Senator Cory Booker (D-N.J.) reintroduced legislation last week to increase protections against exposure to toxic pesticides. The Protect America’s Children from Toxic Pesticides Act of 2023 (PACTPA), S.269, addresses many of the controversial issues with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), which governs the registration and use of pesticides in the U.S. This major reform legislation tackles some of the documented deficiencies in the regulation of pesticides and removes a number of loopholes in the law. The legislation, introduced with Senators Kirsten Gillibrand (D-NY), Bernie Sanders (D-VT), Elizabeth Warren (D-MA) and Brian Schatz (D-HI), also includes a ban on all organophosphate and neonicotinoid insecticides, as well as  the weed killer paraquat, which is known to cause Parkinson’s disease and lung fibrosis. Despite these reform provisions, the legislation does not touch the core of FIFRA’s pesticide registration process and chart a path for the systemic, transformative change that Beyond Pesticides says is essential to meet the existential challenges of current times—devastating health threats, biodiversity collapse, and the climate crisis. FIFRA, which is under the jurisdiction of the agriculture committees of Congress, has long been criticized for failing to protect the public and workers […]

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Indoor Air Pollution: Pesticides Continue to Make their Way Into Homes

Wednesday, February 1st, 2023

(Beyond Pesticides, February 1, 2023) A study published in Environment International concurs with previous reports that agricultural pesticide treatment can contaminate nearby residential areas, resulting in indoor chemical exposure via concentrations of insecticide active ingredients in house dust. Pesticide contamination in homes has ties to higher levels of pesticide residue in both human and pet bodies. Some pesticides, like organochlorine compounds, have poor elimination from the body, leading to accumulation over a lifetime. Pesticide exposure can heighten risks of various cancers (i.e., prostate, hepatic, liver, etc.), mental health problems (i.e., depression), respiratory illnesses (asthma), endocrine disruption, and many other pesticide-induced diseases. Extensive pesticide use can predispose human pathogenic to antibiotic resistance, bolstering bacterial virulence. Studies like this are concerning as it reveals that individuals do not have to be in close contact (e.g., chemical manufacturers, farmworker, gardener, custodian, etc.) with pesticides for risky, health-harming exposures to occur. Despite stricter regulations and technological changes beginning to decrease air pollution from cars and other vehicles, scientists are finding that the use of pesticides and other household chemicals represents an increasing proportion of U.S. smog-forming air pollution. Personal care products, cleaning agents, perfumes, paints, printing ink, and pesticides warrant greater attention from regulators for their ability to form toxic fumes that can eventually make their way […]

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Neonicotinoid Insecticides Adversely Affect Nervous System Health, According to Study

Thursday, January 19th, 2023

(Beyond Pesticides, January 19, 2023) Research published in Environmental Health Perspectives finds the presence of nine various neonicotinoids (neonics) and six neonic metabolites within human cerebrospinal fluid (CSF). CSF is an essential part of the central nervous system (CNS), especially for CNS development. Specific chemical biomarkers (measurable indicators of biological state), like pesticides, found in CSF are useful for diagnosing and evaluating numerous neurological diseases. The nervous system is an integral part of the human body and includes the brain, spinal cord, a vast network of nerves and neurons, all of which are responsible for many of our bodily functions—from sensed to movement. However, mounting evidence over the past years shows that chronic exposure to sublethal (low) levels of pesticides can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. The impacts of pesticides on the nervous system, including the brain, are hazardous, especially for chronically exposed individuals (e.g., farmworkers) or during critical windows of vulnerability and development (e.g., childhood, pregnancy). Researchers identify the role agricultural chemicals play in CNS impacts causing neurological diseases, like amyotrophic lateral sclerosis (ALS) and Parkinson’s disease, dementia-like diseases such as Alzheimer’s, and other effects on cognitive function. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood […]

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Pesticides Not Only Linked to Parkinson’s Disease Development, But Accelerating Disease Symptoms

Thursday, January 12th, 2023

(Beyond Pesticides, January 12, 2023) Exposure to certain pesticides among individuals diagnosed with Parkinson’s disease (PD) can increase the risk of symptom progression. According to a study published in Science of the Total Environment, nearly 20 percent of pesticides associated with the onset of PD also increase the risk of faster decline in motor and non-motor function. Several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Past studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the association between PD onset via pesticide exposure patterns, few epidemiologic studies examine the influence pesticides have on worsening motor and non-motor symptoms in PD. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While […]

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Calling for Reform of Pesticide Regulation to Address Health, Biodiversity, and Climate Crises

Monday, January 9th, 2023

(Beyond Pesticides, January 9, 2023) The Biden EPA still needs a new vision in order to meet the existential crises in public health, climate change, and biodiversity. The Trump Environmental Protection Agency (EPA) reversed in four years much of the progress made by the EPA in decades. Despite a broad new perspective embodied in President Biden’s Executive Memorandum (EM) Modernizing Regulatory Review issued on his first day in office, the Biden EPA has not adopted a new direction for regulating pesticides. Tell President Biden, EPA, and Congress to adopt a new direction for pesticide regulation. Immediately following his inauguration, President Joe Biden issued the EM, which directs the heads of all executive departments and agencies to produce recommendations for improving and modernizing regulatory review, with a goal of promoting public health and safety, economic growth, social welfare, racial justice, environmental stewardship, human dignity, equity, and the interests of future generations. This EM could reverse the historical trend of status-quo regulatory reviews required by the White House Office of Management and Budget (OMB) that typically support vested economic interests of polluters (e.g., petroleum-based pesticide and fertilizer manufacturers). The President’s EM sets the stage for the adoption of agency policy across government to […]

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Neonicotinoid Insecticides Add to the Growing List of Chemicals that Transfer between Mother and Fetus

Wednesday, January 4th, 2023

(Beyond Pesticides, January 4, 2022) A study published in Environmental Science and Technology finds neonicotinoids (neonics) and their breakdown products (metabolites), like other chemical pesticide compounds, can readily transfer from mother to fetus. The National Health and Nutrition Examination Survey (NHANES) finds U.S. pregnant women experience frequent exposure to environmental pollutants that pose serious health risks to both mother and newborn. Many known pollutants (i.e., heavy metals, polychlorinated biphenyl, and pesticides) are chemicals that can move from the mother to the developing fetus at higher exposure rates. Hence, prenatal exposure to these chemicals may increase the prevalence of birth-related health consequences like natal abnormalities and learning/developmental disabilities. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Moreover, a mother’s pesticide exposure can have a stronger association with health disorders than childhood exposure, and a newborn can still encounter pesticides. Therefore, it is essential to understand how pesticides impact the health and well-being of individuals during critical developmental periods. Beyond Pesticides has covered a variety of pregnancy risks from pesticides and other toxic chemicals, including these in just the last three years: pesticides and children’s sleep disorders; prenatal exposures to a multitude of chemicals; insecticides and childhood leukemia; insecticides and Attention Deficit/Hyperactivity Disorder. The study […]

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Groups Again Call for Urgent Action to Eliminate Pesticide Industry’s Influence at the United Nations

Thursday, December 22nd, 2022

(Beyond Pesticides, December 22, 2022) International health and environmental groups submitted an urgent letter to  the United Nations Food and Agriculture Organization (FAO) late last month demanding “greater transparency and accountability” through termination of the agency’s two-year-old partnership with CropLife International (CLI), a global trade association representing the world’s biggest pesticide manufacturers. Addressed to FAO Deputy Director Beth Bechdol ahead of FAO Council 171 session in Rome and COP15, the letter outlines a unique opportunity for the organization to lead the phaseout of fossil-fuel based food systems and use of agrochemicals while upholding the agency’s responsibility to act in response to conflicts of interest and human rights violations.   The original Letter of Intent (LOI), signed between CLI President and CEO Guilia Di Tommaso and FAO Director-General Qu Dongyu in October 2020, framed the partnership as a means to ensure humanity’s freedom from hunger while advancing Sustainable Development Goals. However, according to PAN Europe Policy Officer Manon Rouby, “While the private sector has been working with FAO for years, this official agreement with CropLife directly threatens FAO’s work on supporting farmers in the transition towards agroecology, while reducing the harms of synthetic pesticides worldwide. With CropLife members being the largest agrichemical […]

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Mother and Child Health: Learning Disorders and Prenatal Pesticide Exposure Study Results Released

Tuesday, December 20th, 2022

(Beyond Pesticide, December 20, 2022) A meta-analysis published in Chemosphere finds prenatal pesticide exposure, or pesticide exposure during pregnancy has a positive association with autism spectrum disorder (ASD) and attention deficit/hyperactive disorder (ADHD). Particularly, exposure to chemical classes organophosphate (OP) and pyrethroid (PYR) insecticides, in addition to the mother’s age during pregnancy (≥30 years old), increased the risk factor of ASD. ADHD risk increases among offspring whose mothers encounter organochlorine pesticides (OCPs) during gestation. The etiology or cause of ASD and ADHD involves the interaction of multiple components, including lifestyle and genetics. However, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, solvents, dietary residues, etc.) play a role in disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues resulting in chronic health effects.  ADHD is estimated to affect 8-12% of school-age children worldwide. While it is a complex disease, and genetics may play a role, no specific genes have been identified, and there is increasing evidence that environmental factors like pesticide exposure facilitate the development of the condition. Additionally, U.S. Centers for Disease Control and Prevention (CDC) estimates that 1 in 54 children have been diagnosed with an autism spectrum […]

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Estrogen-Mediated Cancers in Humans Have Links to Endocrine Disrupting Pesticides

Tuesday, December 13th, 2022

(Beyond Pesticides, December 13, 2022) Pesticides have a long history associated with hormone (endocrine)-disrupting properties that induce various molecular changes, prompting disease development. Adding to the science, a review published in Environmental Exposure, Biomonitoring and Exposure Assessment highlights how specific estrogen-mimicking pesticides increase the risk of disease, particularly hormone-related cancers among women (i.e., breast, ovarian, endometrial cancer) and men (i.e., testicular, prostate cancer). Like pesticides, endocrine disruptors are xenobiotic (i.e., chemical substances foreign to an organism or ecosystem). Many reports demonstrate that exposure to endocrine-disrupting chemicals can adversely affect human, animal—and thus environmental—health by altering the natural bodily hormones responsible for conventional reproductive, physical, and mental development. Endocrine disruption can lead to several health problems, including hormone-related cancer development (i.e., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Therefore, studies related to pesticides and endocrine disruption help scientists understand the underlying mechanisms that indirectly or directly cause cancer, among other health issues. Pesticides are one of the most potent xeno-estrogenic compounds, as estrogenic strength and environmental half-life exceed those of other xeno-estrogenic compounds. Focusing on organochlorine pesticides (OCs), the study evaluates the chemical effects on the physiological (anatomic) system to increase cancer risk. Using human studies, researchers assessed how estrogen-medicated cancer develops in women and men. […]

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Childhood Pesticide Exposure Associated with Early Onset of Puberty

Thursday, December 8th, 2022

(Beyond Pesticides, December 8, 2022) Children with higher levels of certain pesticide metabolites are more likely to go through early puberty, according to research published recently in Environmental Pollution. The findings by a team of Spanish researchers speak to a need for greater protections for children from toxic pesticide exposure. Children are much more sensitive to pesticide exposure than adults as they take in greater amounts of toxics relative to their body weight and have developing organ systems. Managing homes and yards without chemicals and purchasing organic food whenever possible can significantly reduce childhood pesticide exposure.   Researchers began their investigation with children aged 7-11 participating in the Spanish state’s Environment and Childhood multicenter birth cohort stud, an ongoing project aimed at understanding the effect of environmental exposures on pregnancy, fetal, and childhood development in the country. Out of over 3,000 children enrolled in the project, 1,539 had their urine sampled for the presence of pesticide metabolites. Scientists focused on four insecticides breakdown products—a chlorpyrifos metabolite ‘TCPy’, a metabolite of the organochlorine diazinon ‘IMPy’, a general organophosphate metabolite ‘DETP’, the pyrethroid metabolite ‘3-PBA’, and a metabolite of ethylene-bis-dithiocarbamate fungicides ‘ETU’. Urinary levels of these pesticide metabolites were then compared against […]

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Ocean Health: Environmental Pollutants Threaten Humpback Whale Reproduction and Offspring

Tuesday, December 6th, 2022

(Beyond Pesticides, December 6, 2022) Persistent organic pollutants (POPs)—including banned pesticides—present a health risk to humpback whales (Megaptera novaeangliae), according to a study published in Environmental Pollution. Regarding female humpback whales, levels of POPs in blubber are higher in juveniles and subadults than in adults, primarily from the transference of contaminants from the mother to her calf.  Organochlorine compounds (OCs), such as organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), are well-known persistent organic pollutants. The international Stockholm Convention treaty (signed by 152 countries, but not the U.S.) banned these primary pollutants of concern (UNEP, 2009) in 2001 (taking effect in 2004) because of their persistence, toxicity, and adverse effects on environmental and biological health. These pollutants have a global distribution, with evaporation and precipitation facilitating long-range atmospheric transport, deposition, and bioaccumulation of hazardous chemicals in the environment. However, these chemicals can remain in the environment for decades and interact with various current-use pesticides, including organophosphates, neonicotinoids, and pyrethroids. Although various studies demonstrate the volatile, toxic nature of POPs, much less research evaluates the impact POPs have on maternal offloading or transfer of contaminates to offspring and respective health consequences. The globe is currently going through the Holocene Extinction, Earth’s 6th mass extinction, with one […]

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