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Crusade for Local Democracy; The Saga of State Preemption Continues Into 2024

Tuesday, January 23rd, 2024

(Beyond Pesticides, January 23, 2024) Earlier this month, a coalition of over 140 local and state elected officials from over 30 states sent a letter to ranking members of the House and Senate Agriculture committees to reject the proposed Agricultural Labeling Uniformity Act (H.R. 4288), which would preempt local governments’ authority to protect their constituents from toxic pesticides. Members of Congress are negotiating language in the Farm Bill that would preempt local and state authority to restrict pesticides. “We write to express our strong opposition to any efforts to limit longstanding state and local authority to protect people, animals, and the environment by regulating pesticides,” says the signatories. “As Congress considers legislation related to agriculture, including the reauthorization of the Farm Bill and Fiscal Year 2024 appropriations bills, we urge you to ensure that state, county, and local governments retain the right to protect their communities and set policies that best suit our local needs.” The question of local rights to adopt more stringent restrictions on pesticide use has historically been left to the states. However, after the U.S. Supreme Court (Wisconsin v. Mortier, 1991) affirmed the rights of local communities under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), […]

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Study Shines Light on Common Herbicides 2,4-D and Glyphosate Impacts on Behavioral Function

Friday, January 19th, 2024

(Beyond Pesticides, January 19, 2024) A study published in Environmental Health Perspective is one of the first to indicate a link between exposure to the herbicides 2,4-D and glyphosate and the impairment of behavioral performance (i.e., attention/inhibitory control, memory/learning, language, visuospatial processing, and social perception). These adverse effects associated with the neurotoxic impacts of pesticides on behavior have been previously documented. For example, a study in August 2023 finds oral intake (e.g., eating contaminated foods), inhalation, and dermal exposure to glyphosate lowered cognitive function scores, increased the likelihood of severe depressive symptoms, and impaired auditory (hearing) function. Although previous studies find neurotoxic effects from exposure to these herbicides, very few until now have evaluated how this neurotoxic exposure impacts neurotypical behavior among youth (children and teenagers). The ubiquitous use of glyphosate and 2,4-D use in agriculture—which leaves residues of the toxic chemicals in food and in public areas (e.g., parks and walkways) creates a creates a significant risk for exposure. Glyphosate is already implicated in or proven to lead to the development of numerous health anomalies, including cancer, while 2,4-D also has a range of potential hazards, including cancer. Therefore, studies like this help local and government officials make holistic decisions regarding the use […]

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Researchers Raise Alarm about Ingested Nanoscale Microplastic Particles Not Previously Evaluated

Thursday, January 18th, 2024

(Beyond Pesticides, January 18, 2024) Research continues to raise alarms about the hazards associated with the use of plastic, including the microplastic particles that are distributed in alarming amounts throughout the environment and taken up by organisms, including humans. A study published by researchers at Columbia and Rutgers universities (see article in the Proceedings of the National Academy of Sciences, January 2024) reports that the average liter of three brands of bottled water in the U.S. contains almost a quarter of a million tiny plastic pieces, of which 90 percent are at the nanoscale. The other ten percent are slightly larger, at microscale. Last December, researchers at Norway’s MicroLEACH project published a study that analyzes the components of 50 items in common use—plastic bags, disposable cups, dishwashing gloves, car tire granules, children’s toys and balloons. (See summary.) The researchers found, like in previous studies, that many hazardous chemicals in the plastics as well as many that could not be identified because they were not listed in the major chemical substance databases. Only 30 percent of the chemical compounds identified in the study were present in two or more products. This suggests that most plastics contain many unidentified chemicals, far beyond […]

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Mental Health: Pesticides Continue to Impact the Body and Mind, Especially for Farmers

Wednesday, January 17th, 2024

(Beyond Pesticides, January 17, 2024) Science continues to find a link between mental health and occupational (work-related) chemical exposure, with a study published in Toxicology finding an increased risk of depression among farmers exposed to pesticides. Conventional, chemical-intensive farming is a profession notorious for higher-than-average pesticide exposure occurrences, thus explaining why the study concludes that individuals within this occupation can suffer from chemically induced oxidative stress, inflammation, and lower education-based cognition that exacerbate depressive symptoms. However, besides psychological symptoms, the study indicates potential physiological issues from pesticide exposure, such as renal (kidney) and hepatic (liver) issues. Studies like this one can directly pinpoint risks of developing depression, especially among agricultural workers and landscapers who use pesticides. Usually, research on pesticide-induced diseases commonly investigates pesticide exposure concerning the development of various physical illnesses. However, previous studies show that occupational risks of developing depression are high in agriculture, where pesticide use is rampant. Acute exposure to chemicals, including organophosphate, organochlorine, triazine, and carbamate pesticides, tends to put farmers at greater risk of suicide than the general population. There is a lack of information connecting pesticide exposure to the subsequent psychological (psychiatric) effects on the general population. Although the etiology of depression—and many other psychiatric disorders—is often genetic, […]

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Take Action: EPA Challenged for Not Assessing Claimed Pesticide “Benefits,” Opens Public Comment Period

Tuesday, January 16th, 2024

(Beyond Pesticides, January 16, 2024) The U.S. Environmental Protection Agency (EPA) has long been criticized for its failure to evaluate the effectiveness (or efficacy) of all the pesticides it registers. A petition, for which there is now an open public comment period (submit comments by January 22, 2024), challenges what advocates call a basic failure of the agency to evaluate the claimed benefits of pesticides. Because of this long-standing situation, those who purchase pesticides do not know that the pesticides they buy will meet expectations for control. For farmers, that means that EPA has not evaluated whether the pesticide’s use actually increases productivity of the treated crops and/or whether over time the target pest (weed, insect, fungus) will become resistant. For consumers, it also means that there is not an independent analysis of whether the pesticide products work. As EPA implements the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), not only is there no agency assessment of whether the pesticide’s use will achieve its intended purpose, there is not a determination as to whether there is a less toxic way of achieving the pest management goal. As Beyond Pesticides cited last year, a piece published in the Proceedings of the […]

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Pesticides’ Role in Lower Sperm Counts and Reproductive Harm in Men Again in Science Literature

Wednesday, January 10th, 2024

(Beyond Pesticides, January 10, 2024) Exposure to endocrine-disrupting chemicals (EDCs) negatively impacts testicular function and may cause sperm count declines over time, according to a 2022 review published in Endocrine. The findings indicate that this occurs regardless of whether exposure is prenatal (before birth) or postnatal (after birth). More recent work from October 2023 confirms the connection between male reproductive health and exposure to organophosphate and carbamate insecticides and the weed killer glyphosate—as many pesticide products containing these chemicals are classifiable as endocrine disruptors (ED). Just last year, a meta-analysis from researchers at Mount Sinai Medical Center, the Hebrew University of Jerusalem, and the University of Copenhagen, among others, finds that the drop in global sperm count is accelerating, dropping by 51.6 percent from 1973 through 2018. The U.S. regulatory system, under the authority of the U.S. Environmental Protection Agency (EPA), has not kept pace with the science and does not fully evaluate pesticides in wide use for endocrine disruption, despite a requirement in 1996 law (the Food Quality Protection Act) to begin that testing and evaluation nearly three decades ago. In 2021, Beyond Pesticides reported that the Office of the Inspector General (OIG) for EPA issued a damning report on the […]

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Field Study of Bumble Bees Finds Exposure to Chemical Mixtures, High Hazard, Flawed Regulation

Tuesday, January 9th, 2024

(Beyond Pesticides, January 9, 2024) A “landscape-level” study finds that typical risk assessment studies used by the U.S. Environmental Protection Agency (EPA) and European regulators fail to “safeguard bees and other pollinators that support agricultural production and wild plant pollination.” The study, published in Nature (November 2023), evaluates the health of bumble bees (Bombus terrestris) as a sentinel species placed in 106 agricultural landscapes across Europe. The authors’ conclusions challenge “the current assumption of pesticide regulation—that chemicals that individually pass laboratory tests and semifield trials are considered environmentally benign”—calling into question EPA’s persistent failure to adequately regulate mixtures of chemicals to which organisms are exposed in the real world. This study adds to the body of science on pesticide mixtures adversely affecting bee and pollinator health. See here, here, and here. The failure to capture real-world exposure to pesticide mixtures in its regulatory assessments extends to EPA’s systemic failure to evaluate a range of serious adverse impacts, as noted by the agency’s Office of Inspector General (OIG) report. And, aquatic environments also have documented mixtures of pesticides, with the U.S. Geological Survey finding 90 percent of water samples containing at least five or more different pesticides. “We can take no comfort […]

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Commentary: We Can and Must Stop Antibiotic Pesticide Use in the Interest of Public Health Worldwide

Monday, January 8th, 2024

(Beyond Pesticides, January 8, 2024) Despite successful litigation that stopped the unnecessary use of an antibiotic (streptomycin) in citrus production in December 2023, the court’s reasoning fails to grasp the science behind the biggest emerging threat to U.S. and global health—antibiotic resistance. What is most disturbing and challenging is that the U.S. Environmental Protection Agency (EPA), responsible for applying science in the protection of the public’s health, misled the court on the overwhelming worldwide scientific consensus on the contribution of agricultural antibiotic use to the human death and disability rate linked to antibiotic resistance. On this subject, Beyond Pesticides has written extensively about horizontal gene transfer, which explains the movement of antibiotic resistant bacteria throughout the environment, ultimately making their way to people, as medically necessary drugs become ineffective. As we’ve written, “The human pathogenic organisms themselves do not need to be sprayed by the antibiotic because movement of genes in bacteria is not solely “vertical,” that is from parent to progeny—but can be “horizontal”— from one bacterial species to another.” [Regarding the reliance of the court on EPA’s misrepresentation of the science, the court found, ”EPA emphasized that ‘there is no data that antibiotic use in agriculture leads to […]

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UN Climate Crisis Conference Calls for Phaseout of Fossil Fuels, which Are Used to Produce Pesticides and Fertilizers

Friday, January 5th, 2024

(Beyond Pesticides, January 5, 2023) The 28th United Nations Climate Change Conference of the Parties (COP28) wrapped up in Dubai on December 13 with what some hailed as a breakthrough agreement among almost 200 countries to reduce fossil fuel consumption that signals “the eventual end of the oil age.” To be successful and assure human survival, eliminating oil, gas, and coal use, Beyond Pesticides is calling for the elimination of petrochemical pesticides and fertilizers and support for organic, regenerative agriculture around the world. Because of the insurmountable crises that are caused or exacerbated by petrochemical pesticides and fertilizers, the adoption of organic land management practices and the need for foundational change in federal, state, and local policies and practices has come into focus. Under organic management, healthy soil can absorb and store 1,000 pounds of carbon per acre foot of soil annually. This translates to about 3,500 pounds of carbon dioxide per acre drawn down from the air and sequestered into organic matter in soil. (It is noteworthy that use of synthetic fertilizers actually compromises the carbon-capture ability of some kinds of terrain, such as salt marshes.) A fact often overlooked by policy makers in generating climate strategies is that carbon-sequestering soil practices […]

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Work-Related Pesticide Exposure Puts Farmers at Risk of Cognitive (Intellectual) Harm

Thursday, January 4th, 2024

(Beyond Pesticides, January 4, 2024) A review published in the Journal of Neurosciences in Rural Practice finds an association between farmers’ pesticide exposure and cognitive impairment. Specifically, farmers suffer from attention deficit, lack of information processing, non-comprehension of verbal cues, slow processing speed, memory loss, sluggishness, speech difficulties, and impaired motor function. Additionally, the risk of adverse effects from exposure increases with time spent around pesticides, like in other occupational (work-related) settings. Although pesticide exposure may not be the only factor involved in cognitive impairment, exposure can work synergistically (together) with other factors, triggering neurotoxicity. Pesticides play various roles in causing or exacerbating adverse health outcomes like neurotoxic effects and chemical damage to the brain. Numerous pesticides impair neurological function, especially for chronically exposed individuals (e.g., farmworkers) or during critical windows of vulnerability and development (e.g., childhood, pregnancy). Mounting evidence over the past years shows that chronic exposure to sublethal (low) levels of pesticides adversely affects the central nervous system (CNS) and neural receptors, such as connections between nerves, the brain, enzymes, and DNA. Specifically, researchers identify agricultural chemical exposure as a cause of many adverse CNS impacts and neurological diseases, including Alzheimer’s, amyotrophic lateral sclerosis (ALS), and Parkinson’s disease. The researchers reviewed scientific articles published in […]

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Loss of Chromosome Y in Male Farmers Genotoxic Implications for Cancer

Wednesday, January 3rd, 2024

(Beyond Pesticides, January 3, 2024) A study published in Environmental Health Perspectives finds elevated, chronic exposure to glyphosate throughout one’s lifetime increases the risk of mosaic loss of chromosome Y (loss of chromosome Y occurs to many men in some cells due to aging [mLOY]) that impacts a noticeable fraction of cells. Although the loss of this sex chromosome does not cause cell death, like the loss of autosomal chromosomes, the risk of mLOY is a biomarker for genotoxicity (the damage of genetic information within a cell causing mutations from chemical exposure, which may lead to cancer) and expansion of cellular response to glyphosate, resulting in the precursor for hematological (blood) cancers. This study is one of the first to identify sex-specific chromosome degradation, with stark evidence demonstrating links to various cancers, including non-Hodgkin lymphoma. The International Agency for Research on Cancer (IARC) has classified the glyphosate as a probable carcinogen or cancer-causing chemical. However, the U.S. Environmental Protection Agency’s (EPA) allowance of widespread use of glyphosate allows for adverse impacts, especially among vulnerable individuals, like pregnant women, infants, children, and the elderly. Glyphosate exposure levels and resulting residues in urine has been documented with recent data showing that four out of five (81.6%) […]

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Commentary: New Year Calls for Transformational Change Starting with Chemical Use Rejection

Tuesday, January 2nd, 2024

(Beyond Pesticides, January 2, 2024) [photo credit: Alessandro Marongui, Bhopal Medical Appeal, Bhopal, 2009] The new year begins with numerous critical decisions before the U.S. Environmental Protection Agency (EPA) and its Office of Pesticide Programs, along with other federal agencies and the U.S. Congress, that determine whether the agency will continue to erode its leadership position in meeting the existential crises that threaten health, biodiversity, and climate. Given these crises, EPA under its current authority could take the action necessary to advance a transition away from the use of petrochemical pesticides, since under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) the hazards associated with pesticides are “unreasonable”—given the availability and viability of organic systems that do not utilize toxic pesticides. As EPA fails to meet the catastrophic environmental and health challenges of the day, communities and states across the U.S. are increasingly exercising their authority to restrict pesticides more stringently than the federal government. FIFRA, as affirmed by the U.S. Supreme Court in Wisconsin Public Intervenor v. Mortier (1991), does not prohibit or preempt local municipalities from adopting more stringent pesticide restrictions throughout their jurisdictions than the federal government. The U.S. Congress over the next several weeks will continue […]

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Holiday Season and New Year Greetings as We Move Ahead Together for a Sustainable Future

Friday, December 22nd, 2023

On behalf of the Beyond Pesticides team, we wish you and your loved ones a happy and healthy holiday season! We deeply appreciate the vital community-based work taking place across the country as we join together to confront the existential health and environmental challenges of our time. Meeting the challenges ahead with a transformative strategy  Beyond Pesticides shares the vision of people and communities that are striving to ensure a future that protects health and sustains life. We are facing existential crises—the climate crisis, biodiversity collapse, and severe public health threats—from cancer to neurological, reproductive, and endocrine system effects, including brain and behavioral impacts. To reverse these threats —which we can do— we advance model organic solutions that eliminate billions of pounds of fossil fuel-based pesticides and synthetic fertilizers and nurture biological systems that take dangerous pollutants out of our environment, protecting health and the ecosystems that sustain life.     Our audacious goal: to phase out petrochemical pesticides and fertilizers by 2032. Our solution: to provide hands-on assistance, funded by our supporters, to assist in the transition to organic land management in community parks, playing fields, and schoolyards.  The path moving forward: Advancing sustainable, organic practices and policies to […]

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Low-Dose Chronic Glyphosate Exposure Increases Diet-Induced Non-Alcoholic Fatty Liver Disease

Thursday, December 21st, 2023

(Beyond Pesticides, December 21, 2023) A new study published in Environmental Toxicology and Pharmacology adds to prior research indicating glyphosate promotes the occurrence of nonalcoholic fatty liver disease (NAFLD) through diet by causing liver inflammation and oxidative stress. More importantly, the predisposition for NAFLD occurred at levels within toxicological limits, which are doses of glyphosate classified as causing no adverse effects or No Observed Adverse Effect Level (NOAEL). NAFLD is a condition that causes swelling of the liver and can eventually lead to cirrhosis, cancer, or liver failure. This study highlights the Westernized diet (WD), comprised of foods enriched in saturated fats, cholesterol, and simple carbohydrates (e.g., fructose, glucose, and sucrose), plays a role in the nearly 40 percent increased risk of NAFLD. Although glyphosate disrupts gut microbes and induces liver inflammation, oxidative stress, and fatty acid levels that promote NAFLD, the combination of WD and glyphosate reduces the threshold risk for NAFLD development. NAFLD is a growing worldwide epidemic, becoming the most prevalent form of liver disease and impacting at least 25 percent of the globe. Therefore, studies like this shed light on how diet and chemical exposure can work synergistically (together) to exacerbate disease risk. The study evaluates whether choric […]

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Court Finds EPA Allowance of Antibiotic Streptomycin Use on Citrus Illegal

Wednesday, December 20th, 2023

(Beyond Pesticides, December 20, 2023) A federal district court decision last week (December 13) found illegal the U.S. Environmental Protection Agency’s (EPA) decision to register the antibiotic streptomycin for use in Florida citrus to control Huanglongbing (HLB), also known as “citrus greening,” a plant disease spread by the Asian citrus psyllid. This decision comes just as EPA may allow yet another controversial pesticide, aldicarb, whose registration faces similar issues of agency malfeasance. The streptomycin lawsuit, filed in 2021 by a coalition of farmworker and public interest groups including Beyond Pesticides, raises critical issues of antibiotic resistance, public health protection, and impacts on bees. The case was filed by: Natural Resources Defense Council and U.S. PIRG, represented by NRDC; Beyond Pesticides, Environmental Confederation of Southwest Florida (ECOSWF), Farmworker Association of Florida, Farmworker Justice, and Migrant Clinicians Network, represented by Earthjustice; and the Center for Biological Diversity, represented by in-house counsel. The Ninth Circuit Court of Appeals took EPA to task for its failure to conduct required analyses and issue findings to support the use of streptomycin for citrus greening. The court is particularly concerned about the agency’s failure to reach findings on the impacts on bees and the agency’s responsibility for […]

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Groups Petition EPA to Remove from the Market the Weed Killer Glyphosate

Tuesday, December 19th, 2023

(Beyond Pesticides, December 19, 2023) Last week, farmworker organizations and Beyond Pesticides, represented by the Center for Food Safety, filed a petition with the U.S. Environmental Protection Agency (EPA) urging that the weed killer glyphosate be removed from the market. The petition cites 200 studies, which represent a fraction of the independent scientific literature on the hazards of glyphosate and formulation ingredients of glyphosate products. This action follows previous litigation in 2022 in which a federal court of appeals struck down EPA’s human health assessment, finding that the agency wrongfully dismissed glyphosate’s cancer risk. The farmworker groups petitioning include Farmworker Association of Florida, OrganizaciĂłn en California de Lideres Campesinas, Alianza Nacional de Campesinas, and the Rural Coalition.   Meanwhile, verdicts against glyphosate’s manufacturer, Bayer, continue to pile up with a December jury verdict in Pennsylvania awarding $3.5 million and a November jury in Missouri ordering $1.56 billion to be paid to four plaintiffs. All link their cancer to use of the Roundup. Bayer has lost almost all of the cases filed against it for compensation and punitive damages associated with plaintiffs’ charge that its product (previously manufactured by Monsanto) caused them harm.  The petition summarizes its purpose and justification as […]

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Int’l Group of Scientists Calls for Restraints on Conflicts of Interest in Publications and Regulation

Friday, December 15th, 2023

(Beyond Pesticides, December 15, 2023) Drawing on a recent gathering of international scientists, a group of 34 scientists published a call for much stricter scrutiny of researchers’ conflicts of interest by agencies that regulate and register chemicals, with recommendations for the newly formed Intergovernmental Science Policy Panel. Writing in Environmental Science & Technology, the authors, led by Andreas Schäffer of Aachen University in Germany and Martin Scheringer of Masaryk University in the Czech Republic, cite an abundance of examples of chemical companies and their trade associations manufacturing doubt via an array of techniques, resulting in agencies such as the U.S. Environmental Protection Agency (EPA) dropping certain provisions from rulemaking, ignoring scientific consensus, and keeping chemicals on the market—and in the environment—that many scientists say should be entirely banned. The authors produced the article in response to this webinar to discuss how to ensure that U.N. panels dealing with global crises get the most sound scientific advice conducted by the International Panel on Chemical Pollution. Over the last four decades or so, the notion that conflicts of interest affect the validity of scientific research and professional opinions has been steadily eroded. Regulators wallow in compromised research, hamstrung by political pressure and […]

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EPA May Allow Highly Neurotoxic Insecticide, Aldicarb, for Citrus Despite Ban in 2010 for Same Use

Thursday, December 14th, 2023

(Beyond Pesticides, December 14, 2023) It has been reported that the U.S. Environmental Protection Agency (EPA) is again considering allowing the use of the highly neurotoxic, carbamate insecticide aldicarb for use in Florida citrus, 13 years after the agency and the chemical’s manufacturer, Bayer Crop Science, announced that it was being banned (technically voluntarily canceled). A version of the current EPA proposal and the resource-intensive review process in EPA’s Office of Pesticide Programs—all being done at taxpayers’ expense—was rebuffed, first by the Florida Department of Agriculture and Consumer Services (April 2021), then by a U.S. Court of Appeals (June 2021). Internal EPA emails, as reported in The New Lede (November 21, 2023), expose the extent to which the agency’s science and political staff have tried to downplay aldicarb’s adverse health and environmental outcomes in order to meet the EPA’s broad, and often described as loose, risk parameters.  This Daily News piece on aldicarb is part of an ongoing story of the politicization of science by political appointees to an agency that is charged with protecting public health and the environment. The degree to which agency scientific staff are complicit in advancing agency positions that are not supported by the scientific […]

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Pesticides Used in Production of Baby Food Ingredients Raise Alarm. . . Again

Friday, December 8th, 2023

(Beyond Pesticides, December 8, 2023) Nine pesticides have been found in nearly 40% of nonorganic conventional baby foods tested, according to a study conducted by Environmental Working Group (EWG). The study found no residues of the pesticides studied in a sample of certified organic baby food. While the study finds no traces of the highly neurotoxic insecticide chlorpyrifos, associated with brain damage in children, the chemical has been allowed back on the agricultural market after being removed in 2021—raising an alarm for parents who purchase baby food with ingredients grown in chemical-intensive (“conventional”) agriculture. In November 2023, a three-judge panel of the Eighth Circuit Court of Appeals reversed a 2021 U.S. Environmental Protection Agency (EPA) decision to ban chlorpyrifos’ agricultural uses, which came after a 2021 Ninth Circuit Court of Appeals decision found that the agency’s inaction violated federal pesticide law. Because of its neurotoxic effects on children, EPA had in 2000 negotiated Dow Chemical’s voluntary cancellation of most residential uses of the chemical, but left virtually all of the chemical’s agricultural uses in place. While the EWG study focuses on pesticide residues in food and the hazards associated with ingestion of dangerous chemicals, raising alarms, purchasing baby food processed with nonorganic […]

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Paraquat—The Continuing Environmental Threat Among All Species

Thursday, December 7th, 2023

(Beyond Pesticides, December 7, 2023) A new review published in Ecotoxicology reiterates what past studies have repeatedly stated: the herbicide paraquat (PQ) has profound adverse effects on wildlife at environmentally relevant concentrations. Moreover, these adverse effects span beyond the wilderness, as exposure to this highly toxic herbicide also impacts the health of people working with this chemical (e.g., pesticide applicators) or living adjacent to areas of chemical use. Current data gaps regarding the effects of environmentally relevant concentrations and exposure times, population- or ecosystem-level effects, and biomagnification potential contribute to the uncertainty of predicting risk from environmental PQ exposure. Furthermore, Beyond Pesticides has previously pointed out deficiencies in the U.S. Environmental Protection Agency’s (EPA) ecological risk assessments for paraquat, highlighting failures to perform complete evaluations of the impacts of pesticides on threatened and endangered species. All this occurs amid documented threats to biodiversity from the combined effects of pesticides and climate change.  The review investigated paraquat in the environment, the chemical’s toxicity to nontarget species, and significant data gaps. Overall, the long-term risks of environmental PQ contamination for human and ecological communities can be challenging since the potential chronic effects from extended use are nearly unstudied. Most concerning is that PQ is […]

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Prenatal and Early Life Exposure to Glyphosate Herbicides Induce Hormonal Effects Disrupting Sleep and Neurodegenerative Diseases

Wednesday, December 6th, 2023

(Beyond Pesticides, December 6, 2023) A study published in Antioxidants finds prenatal and early life exposure, usually after birth (perinatal), to glyphosate-based herbicides (GBH) induce oxidative stress in the brain, causing damage and negatively affecting melatonin levels. Melatonin is a hormone responsible for regulating circadian rhythm to mitigate sleep disorders. Disruption of melatonin levels also has implications for the development of age-associated neurodegenerative diseases, as melatonin is a neuroprotector against neurodegenerative diseases associated with aging. Additionally, GBH can alter molecules in the pineal gland in the brain, resulting in neurodegenerative diseases like Alzheimer’s disease (AD) and Parkinson’s disease (PD). Levels of inadequate sleep patterns are rising among the global population. Reports find variability in sleep duration results in higher rates of depression, anxiety, and fatigue. Since sleep is an essential factor in normal brain development, disturbance in sleep patterns, such as sleeping too much or too little, can result in long-term associations with the brain’s white matter integrity (responsible for age-dependent cognitive function). The study warns, “Since decreased levels of the important antioxidant and neuroprotector melatonin have been associated with an increased risk of developing neurodegenerative disorders, this demonstrates the need to consider the melatonin hormone system as a central […]

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Upcoming EPA Review of Nitrates in Waterways Raises Health and Environmental Questions About Synthetic Nitrogen Fertilizer Use

Tuesday, December 5th, 2023

Upcoming EPA Review of Nitrates in Waterways Raises Health and Environmental Questions About Synthetic Nitrogen Fertilizer Use. In  a quiet reversal of a 2018 Trump administration decision, EPA is resuming an evaluation of the health impacts of nitrate in water, reflecting the long-standing and mounting evidence of synthetic nitrogen’s adverse effects on human health and the environment, particularly in vulnerable communities.

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Study Confirms Connection Between Exposure to Pesticides and Male Reproductive Problems

Friday, December 1st, 2023

(Beyond Pesticides, December 1, 2023) Even though researchers have noted since the 1970s that human fertility appears to be declining globally, doubt is still circulating that it is really happening and that pesticides could have anything to do with it. Very recently published studies, however, make it clear that, even without exact elucidation of the mechanisms by which pesticides damage male fertility, there is an unmistakable association of pesticides and many aspects of male reproductive health. One of the new studies, a meta-analysis of 25 studies on the connection between pesticides and male reproductive problems, finds that men exposed to organophosphate (such as glyphosate and malathion) and carbamate (such as carbaryl and methiocarb) insecticides have lower sperm concentrations than the general population. This is especially true of men exposed in work settings. The senior author of the study, Melissa J. Perry,ScD of the George Mason University College of Public Health, told HealthNews, “The evidence available has reached a point that we must take regulatory action to reduce insecticide exposure.” Human infertility is defined as “the failure to achieve pregnancy after 12 months or more of regular unprotected sexual intercourse.” Most public attention regarding infertility focuses on women’s difficulties in getting […]

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