(Beyond Pesticides, December 21, 2023) A new study published in Environmental Toxicology and Pharmacology adds to prior research indicating glyphosate promotes the occurrence of nonalcoholic fatty liver disease (NAFLD) through diet by causing liver inflammation and oxidative stress. More importantly, the predisposition for NAFLD occurred at levels within toxicological limits, which are doses of glyphosate classified as causing no adverse effects or No Observed Adverse Effect Level (NOAEL). NAFLD is a condition that causes swelling of the liver and can eventually lead to cirrhosis, cancer, or liver failure. This study highlights the Westernized diet (WD), comprised of foods enriched in saturated fats, cholesterol, and simple carbohydrates (e.g., fructose, glucose, and sucrose), plays a role in the nearly 40 percent increased risk of NAFLD. Although glyphosate disrupts gut microbes and induces liver inflammation, oxidative stress, and fatty acid levels that promote NAFLD, the combination of WD and glyphosate reduces the threshold risk for NAFLD development. NAFLD is a growing worldwide epidemic, becoming the most prevalent form of liver disease and impacting at least 25 percent of the globe. Therefore, studies like this shed light on how diet and chemical exposure can work synergistically (together) to exacerbate disease risk. The study evaluates whether choric […]

(Beyond Pesticides, December 20, 2023) A federal district court decision last week (December 13) found illegal the U.S. Environmental Protection Agency’s (EPA) decision to register the antibiotic streptomycin for use in Florida citrus to control Huanglongbing (HLB), also known as “citrus greening,” a plant disease spread by the Asian citrus psyllid. This decision comes just as EPA may allow yet another controversial pesticide, aldicarb, whose registration faces similar issues of agency malfeasance. The streptomycin lawsuit, filed in 2021 by a coalition of farmworker and public interest groups including Beyond Pesticides, raises critical issues of antibiotic resistance, public health protection, and impacts on bees. The case was filed by: Natural Resources Defense Council and U.S. PIRG, represented by NRDC; Beyond Pesticides, Environmental Confederation of Southwest Florida (ECOSWF), Farmworker Association of Florida, Farmworker Justice, and Migrant Clinicians Network, represented by Earthjustice; and the Center for Biological Diversity, represented by in-house counsel. The Ninth Circuit Court of Appeals took EPA to task for its failure to conduct required analyses and issue findings to support the use of streptomycin for citrus greening. The court is particularly concerned about the agency’s failure to reach findings on the impacts on bees and the agency’s responsibility for […]

(Beyond Pesticides, December 19, 2023) Last week, farmworker organizations and Beyond Pesticides, represented by the Center for Food Safety, filed a petition with the U.S. Environmental Protection Agency (EPA) urging that the weed killer glyphosate be removed from the market. The petition cites 200 studies, which represent a fraction of the independent scientific literature on the hazards of glyphosate and formulation ingredients of glyphosate products. This action follows previous litigation in 2022 in which a federal court of appeals struck down EPA’s human health assessment, finding that the agency wrongfully dismissed glyphosate’s cancer risk. The farmworker groups petitioning include Farmworker Association of Florida, Organización en California de Lideres Campesinas, Alianza Nacional de Campesinas, and the Rural Coalition.   Meanwhile, verdicts against glyphosate’s manufacturer, Bayer, continue to pile up with a December jury verdict in Pennsylvania awarding $3.5 million and a November jury in Missouri ordering $1.56 billion to be paid to four plaintiffs. All link their cancer to use of the Roundup. Bayer has lost almost all of the cases filed against it for compensation and punitive damages associated with plaintiffs’ charge that its product (previously manufactured by Monsanto) caused them harm.  The petition summarizes its purpose and justification as […]

(Beyond Pesticides, December 15, 2023) Drawing on a recent gathering of international scientists, a group of 34 scientists published a call for much stricter scrutiny of researchers’ conflicts of interest by agencies that regulate and register chemicals, with recommendations for the newly formed Intergovernmental Science Policy Panel. Writing in Environmental Science & Technology, the authors, led by Andreas Schäffer of Aachen University in Germany and Martin Scheringer of Masaryk University in the Czech Republic, cite an abundance of examples of chemical companies and their trade associations manufacturing doubt via an array of techniques, resulting in agencies such as the U.S. Environmental Protection Agency (EPA) dropping certain provisions from rulemaking, ignoring scientific consensus, and keeping chemicals on the market—and in the environment—that many scientists say should be entirely banned. The authors produced the article in response to this webinar to discuss how to ensure that U.N. panels dealing with global crises get the most sound scientific advice conducted by the International Panel on Chemical Pollution. Over the last four decades or so, the notion that conflicts of interest affect the validity of scientific research and professional opinions has been steadily eroded. Regulators wallow in compromised research, hamstrung by political pressure and […]

(Beyond Pesticides, December 14, 2023) It has been reported that the U.S. Environmental Protection Agency (EPA) is again considering allowing the use of the highly neurotoxic, carbamate insecticide aldicarb for use in Florida citrus, 13 years after the agency and the chemical’s manufacturer, Bayer Crop Science, announced that it was being banned (technically voluntarily canceled). A version of the current EPA proposal and the resource-intensive review process in EPA’s Office of Pesticide Programs—all being done at taxpayers’ expense—was rebuffed, first by the Florida Department of Agriculture and Consumer Services (April 2021), then by a U.S. Court of Appeals (June 2021). Internal EPA emails, as reported in The New Lede (November 21, 2023), expose the extent to which the agency’s science and political staff have tried to downplay aldicarb’s adverse health and environmental outcomes in order to meet the EPA’s broad, and often described as loose, risk parameters.  This Daily News piece on aldicarb is part of an ongoing story of the politicization of science by political appointees to an agency that is charged with protecting public health and the environment. The degree to which agency scientific staff are complicit in advancing agency positions that are not supported by the scientific […]

(Beyond Pesticides, December 8, 2023) Nine pesticides have been found in nearly 40% of nonorganic conventional baby foods tested, according to a study conducted by Environmental Working Group (EWG). The study found no residues of the pesticides studied in a sample of certified organic baby food. While the study finds no traces of the highly neurotoxic insecticide chlorpyrifos, associated with brain damage in children, the chemical has been allowed back on the agricultural market after being removed in 2021—raising an alarm for parents who purchase baby food with ingredients grown in chemical-intensive (“conventional”) agriculture. In November 2023, a three-judge panel of the Eighth Circuit Court of Appeals reversed a 2021 U.S. Environmental Protection Agency (EPA) decision to ban chlorpyrifos’ agricultural uses, which came after a 2021 Ninth Circuit Court of Appeals decision found that the agency’s inaction violated federal pesticide law. Because of its neurotoxic effects on children, EPA had in 2000 negotiated Dow Chemical’s voluntary cancellation of most residential uses of the chemical, but left virtually all of the chemical’s agricultural uses in place. While the EWG study focuses on pesticide residues in food and the hazards associated with ingestion of dangerous chemicals, raising alarms, purchasing baby food processed with nonorganic […]

(Beyond Pesticides, December 7, 2023) A new review published in Ecotoxicology reiterates what past studies have repeatedly stated: the herbicide paraquat (PQ) has profound adverse effects on wildlife at environmentally relevant concentrations. Moreover, these adverse effects span beyond the wilderness, as exposure to this highly toxic herbicide also impacts the health of people working with this chemical (e.g., pesticide applicators) or living adjacent to areas of chemical use. Current data gaps regarding the effects of environmentally relevant concentrations and exposure times, population- or ecosystem-level effects, and biomagnification potential contribute to the uncertainty of predicting risk from environmental PQ exposure. Furthermore, Beyond Pesticides has previously pointed out deficiencies in the U.S. Environmental Protection Agency’s (EPA) ecological risk assessments for paraquat, highlighting failures to perform complete evaluations of the impacts of pesticides on threatened and endangered species. All this occurs amid documented threats to biodiversity from the combined effects of pesticides and climate change.  The review investigated paraquat in the environment, the chemical’s toxicity to nontarget species, and significant data gaps. Overall, the long-term risks of environmental PQ contamination for human and ecological communities can be challenging since the potential chronic effects from extended use are nearly unstudied. Most concerning is that PQ is […]

(Beyond Pesticides, December 6, 2023) A study published in Antioxidants finds prenatal and early life exposure, usually after birth (perinatal), to glyphosate-based herbicides (GBH) induce oxidative stress in the brain, causing damage and negatively affecting melatonin levels. Melatonin is a hormone responsible for regulating circadian rhythm to mitigate sleep disorders. Disruption of melatonin levels also has implications for the development of age-associated neurodegenerative diseases, as melatonin is a neuroprotector against neurodegenerative diseases associated with aging. Additionally, GBH can alter molecules in the pineal gland in the brain, resulting in neurodegenerative diseases like Alzheimer’s disease (AD) and Parkinson’s disease (PD). Levels of inadequate sleep patterns are rising among the global population. Reports find variability in sleep duration results in higher rates of depression, anxiety, and fatigue. Since sleep is an essential factor in normal brain development, disturbance in sleep patterns, such as sleeping too much or too little, can result in long-term associations with the brain’s white matter integrity (responsible for age-dependent cognitive function). The study warns, “Since decreased levels of the important antioxidant and neuroprotector melatonin have been associated with an increased risk of developing neurodegenerative disorders, this demonstrates the need to consider the melatonin hormone system as a central […]

Upcoming EPA Review of Nitrates in Waterways Raises Health and Environmental Questions About Synthetic Nitrogen Fertilizer Use. In  a quiet reversal of a 2018 Trump administration decision, EPA is resuming an evaluation of the health impacts of nitrate in water, reflecting the long-standing and mounting evidence of synthetic nitrogen’s adverse effects on human health and the environment, particularly in vulnerable communities.

(Beyond Pesticides, November 29, 2023) A study published in Environment International finds high pesticide exposure incidence associated with shingles, a varicella-zoster virus (the same highly contagious virus that causes chickenpox) that reactivates in the body after having chicken pox. Shingles is a painful condition with a blistering rash that can lead to vision and hearing loss, brain and lung inflammation, and even death if not treated. Since shingles manifest decades after initial exposure, and the association is strongest among individuals already hospitalized for pesticide-related illnesses, researchers find the long-term/chronic effects most concerning. Although dermal pesticide exposure can cause a range of adverse reactions, including dermatitis, allergic sensitization, and cancer, any route of exposure can exacerbate dermal manifestations through immune system response, causing virus-based skin reactions like shingles. People encounter toxic chemicals daily. However, frequent use of pesticides, including the use of everyday products like cleaning supplies, personal care products, agricultural chemicals, fabrics, non-stick cookware, and general airborne pollution, exacerbate chemical exposure risks. Dermal exposure is the most common pesticide exposure route, composing 95 percent of all pesticide exposure incidents, and is a significant concern for occupational (work-related) health. The study notes, “[The] findings of elevated shingles risk associated with acute, clinically relevant pesticide exposures also highlights […]

With the elevated adverse impacts associated with pesticides and reproductive health, the Pregnant Workers Fairness Act (PWFA) law may be used to improve protections for farmworkers and other high-risk employees.

(Beyond Pesticides, November 22, 2023) As a leading organization in advocating for organic and sustainable land management, Beyond Pesticides is honored to host the third and final webinar of the National Forum Series: Transformative Community-Based Change from the Ground Up on November 29, 2023, at 2 PM EST! This event, focusing on managing parks and playing fields with organic practices and policies, invites concerned citizens, elected officials, and land managers to learn about effective strategies for implementing organic land management in their communities. The panel discussion will highlight activists like Avery Kamila, who was instrumental in establishing Portland, Maine’s pioneering ordinance—the strongest local ordinance in the United States—that restricts the use of synthetic pesticides and fertilizers on both public and private properties, with few exceptions. This landmark ordinance establishes organic land care practices as the primary means to maintain properties within Portland’s city limits, including lawns, gardens, sports fields, parks, and playgrounds. Kamila’s efforts, alongside other concerned citizens, led to significant policy changes in Portland, demonstrating the powerful impact of grassroots advocacy. While Maine is one of a handful of states that allow citizens and local governments the right to control their exposure to pesticides through local government pesticide regulation […]

(Beyond Pesticides, November 21, 2023) According to a study in the Scientific Reports Journal, plant-forward diets might increase exposure to pesticide residues compared to meat-heavy diets. However, a switch to organic plant-based options significantly reduces this risk, with a separate research study indicating that vegetarians and vegans—often favoring organic products—are generally less exposed to synthetic pesticides than omnivores. The study also corroborates other research emphasizing the environmental benefits of plant-based diets, advocating for policies that make organic plant-based foods more widely accessible and emphasizing their crucial role in enhancing both environmental and human health.   Plant-based diets are increasingly popular—and with good reason. The intensification of animal agriculture is a major cause of deforestation, greenhouse gas emissions, and high water usage. In particular, Brazil accounts for one-third of global tropical deforestation, with 80% of this deforestation in the Amazon due to cattle ranching. Additionally, animal products like fish, eggs, and meat, responsible for about 83% of land use, supply only 37% of the global protein. Numerous studies suggest that reducing meat and animal product consumption can significantly mitigate environmental impacts, particularly regarding land use and greenhouse gas emissions. However, managed grazing in organic animal agriculture reduces many of the hazards […]

Join Us on November 29, 2023 for our final session centered on grassroots action: Transformative Community-Based Change from the Ground Up: Managing Parks and Playing Fields with Organic Practices and Policies  (Beyond Pesticides, November 17, 2023) Since the beginning of this fall and our first webinar in September, the aim of the National Forum Series has been and continues to be enabling a collective strategy to address the existential health, biodiversity, and climate threats and chart a path for a livable and sustainable future. We come together to empower effective action. You are part of the solution!  Click here to register!  Change is driven by grassroots action of local people, elected officials, and land managers. In this context, the third session of the National Forum will share model approaches to grassroots advocacy, public policy, and land management that teach and implement respect for nature and ecosystem services, such as the natural cycling of nitrogen and disease resistance—resulting in resilient plants, landscapes, parks and playing fields, and control the existential threats to health, biodiversity, and climate. The panelists in this session will focus on organic land management systems that do not utilize petrochemical pesticides and fertilizers but focus on building organic matter […]

(Beyond Pesticides, November 16, 2023) A study published in the Journal of Endocrinological Investigation finds exposure to the insecticide chlorpyrifos and other organophosphates (OPs) has a positive association with the development of erectile dysfunction (ED). Erectile dysfunction, also known as impotence, is the difficulty of getting or keeping an erection. Despite occurring in males later in life (between 40 and 70 years), recent studies highlight this issue emerging among adolescents, highlighting possible hormone imbalances not associated with age. Scientists and health officials already associate pesticide exposure with a decrease in male fertility, including reduced sperm count, quality, and abnormal sperm development. Exposure to many pesticides also profoundly impacts the endocrine (hormone) system, including reproductive health. Globally, ED is increasing, with over 300 million men expected to have ED by 2025. Although age and comorbid conditions (e.g., obesity, diabetes, and hypertension) play a role in ED prognosis, studies, including this one, suggest environmental contaminant exposure can also explain the increasing trend in ED. The study notes, “Future studies are warranted to corroborate these findings, determine clinical significance, and to investigate biological mechanisms underlying these associations.” Using data from the National Health and Nutrition Examination Survey (NHANES), researchers investigated urinary levels of 3,5,6-trichloro-2-pyridinol (TCPy), […]

(Beyond Pesticides, November 15, 2023) A study previously published in the Federation of American Societies for Experimental Biology (FASEB) is drawing renewed attention to the gut microbiome in the scientific community. The study, involving a team including Demetrio Sierra-Mercado, PhD, of the University of Puerto Rico School of Medicine, initially established a link between glyphosate exposure and increased anxiety and fear-related behavior in rats. Glyphosate, a widely-used herbicide, has been detected in trace amounts in fruits, vegetables, grains, and other food and beverages, according to the U.S. Environmental Protection Agency (EPA). Originally deemed safe for humans due to the way it interacts with the shikimic acid pathway—a metabolic route that is absent in humans—glyphosate’s indirect effects on human health are now under scrutiny as the research linking it to anxiety-like behavior grows.  Dr. Sierra-Mercado’s team is expanding on his previous research to take a closer look at the compound’s potential disruption of the gut microbiome, which plays a pivotal role in regulating both physical and mental health. His upcoming study, anticipated in August 2024, aims to delve into the intricate relationship between glyphosate exposure and the gut-brain axis, with a focus on how this may influence neurological and emotional health […]

(Beyond Pesticides, November 14, 2023) One of the Environmental Protection Agency’s (EPA) strongest tools for avoiding responsibility is delay—a tactic that kept cancellation of the neurotoxic pesticide chlorpyrifos at bay for 21 years—until May 2021, when a three-judge panel of the Ninth Circuit Court of Appeals, responded to a petition filed in 2007 by the Natural Resources Defense Council, Pesticide Action Network, and numerous other groups. The Ninth Circuit ordered the agency to quit lollygagging and acknowledge chlorpyrifos’s threat to human health, something the agency had acknowledged already. The Ninth Circuit instructed EPA to either revoke the “safe” tolerances the agency had set for chlorpyrifos’s residue in various foods or demonstrate that they are actually safe. Finally capitulating, EPA issued a final rule in August 2021 revoking all food tolerances for the neurotoxicant. Tell your governor and mayor to adopt policies that support organic land management.  This looked like progress until February 2022, when a different set of petitioners—pesticide companies, U.S. farmer groups, and other countries’ agricultural interests—filed an action in the Eighth Circuit Court of Appeals. On November 3 of this year, a three-judge panel of the Eighth Circuit reversed EPA’s decision, thereby neutralizing the Ninth Circuit’s opinion. Chlorpyrifos, […]

(Beyond Pesticides, November 13, 2023) The news of a federal Appeals Court’s reversal of a U.S. Environmental Protection Agency (EPA) decision in early November calls into question the value of the basic structures, processes, and authorities of pesticide law that the public has been told are protective of health and the environment. After decades of review and litigation, this reversal, especially on a highly neurotoxic insecticide like chlorpyrifos, identifies a fundamentally flawed system that does not protect the health of people, in this case, children’s brains. >>Tell your governor and mayor to adopt policies that support organic land management.  It was EPA’s finding that chlorpyrifos was destructive of the nervous system, particularly in children, and the functioning of the brain that led to an EPA-negotiated chemical company (Corteva/Dow Chemical) settlement in 1999 (took effect in 2000) that removed residential uses of chlorpyrifos from the market. The 2020 EPA decision, 21 years later, to stop agricultural uses followed another Appeals Court decision, departing from the agency’s usually long drawn-out negotiations that ultimately compromise health and the environment. EPA banned agricultural uses of chlorpyrifos in 2016 in the Obama Administration, but the decision was reversed by the Trump Administration in 2017. Because […]

(Beyond Pesticides, November 8, 2023) A study published in Environmental Science and Pollution Research finds organophosphate pesticides (OPs) are linked to an increased asthma prevalence. The study was released just before an 8th Circuit U.S. Court of Appeals November 3 decision vacating EPA’s 2021 decision to cancel all food tolerances for chlorpyrifos and sending it back to the agency. (Required by a 9th Circuit Court of Appeals decision in April 2021 to take action, EPA issued a final rule in August, 2021—in full effect February 28, 2022—after an earlier 9th Circuit decision, concluding that, “EPA is unable to conclude that the risk from aggregate exposure from the use of chlorpyrifos meets the safety standard of the Federal Food, Drug, and Cosmetic Act (FFDCA). Accordingly, EPA is revoking all tolerances for chlorpyrifos.”  Using urinary metabolites of OPs, the study highlights that diethyl phosphate (DEP, the breakdown chemical of chlorpyrifos) has the strongest association with asthma. However, individual and combined exposure to all OPs have a significant link to respiratory disease. The respiratory system is essential to human survival, regulating gas exchange (oxygen-carbon dioxide) in the body to balance acid and base tissue cells for normal function. Damage to the respiratory system can […]

(Beyond Pesticides, November 7, 2023) Two decades after the introduction of genetically engineered, herbicide-resistant crops and the consequential exponential growth in weed killers, Brazil is seeing an increase in childhood cancer. This is the conclusion reached in a comprehensive study spanning 15 years (2004-2019), “Agriculture Intensification and Childhood Cancer in Brazil,” published in Proceedings of the National Academy of Sciences (PNAS) in October. For the past 20 years, soybean herbicides have been killing and sickening children in the Cerrado and Amazon regions–where soybean cultivation is concentrated. The study reveals a link between an increase in soy cultivation and a spike in cases of acute lymphoblastic leukemia (ALL), the most common cancer affecting children, among indirectly exposed populations. Researchers identify pesticide-contaminated drinking water as the driving force behind the increased cancer rates occurring downstream from soybean sites.  In 2003, Brazil legalized its first official genetically modified (GM) crop, welcoming the era of GM soybeans and sparking a radical transformation in its agricultural landscape–for better or worse. The introduction of Monsanto’s Roundup Ready soybean seed promised farmers an efficient and herbicide-resistant alternative to traditional crops. A significant shift occurred in the areas dedicated to soy cultivation in the Cerrado region, tripling from […]

(Beyond Pesticides, November 3, 2023) California joined 10 other states that have laws partially restricting use of bee-toxic neonicotinoid (neonic) insecticides with the enactment of CA AB 363 into law in October, 2023.  California’s new law will ban over-the-counter sales of lawn and garden neonics by 2025, limiting their use to licensed pesticide applicators. The legislation gives the state’s Department of Pesticide Regulation (CA EPA) until June 30, 2029 to take broader action on neonics, if it determines restrictions are necessary. CA 363 will take neonics out of the hands of homeowners, while allowing lawn care companies to continue use. The California law falls short of the strongest state laws in Nevada, New Jersey, and Maine that eliminate all outdoor (nonagricultural) uses of these chemicals, even by lawn care companies. In June, 2023 Nevada became the third state to ban lawn and garden uses of neonics, while Colorado prohibited homeowner use of land and garden neonic products, similar to laws in Maryland, New York, Massachusetts, Rhode Island, and Vermont.  Minnesota recently banned neonic use on state lands and granted its home-rule subdivisions the authority to ban “pollinator-lethal pesticides” (those with bee warning labels) under its state law preempting local authority […]

(Beyond Pesticides, October 31, 2023) With cooler weather setting in and people heading indoors and closing windows, the issue of COVID-19 transmission escalates, as do concerns about toxic chemicals filling the indoor ambient air. As a recent segment of 60 Minutes (October 29, 2023) stresses, COVID-19 spreads elevated public concern and understanding about the importance of ventilation, filtration, and air exchange to indoor air quality. Unfortunately, the concerns about indoor air are not limited to COVID-19 as volatile organic compounds (VOCs) invade most spaces where people live and work. These invisible toxic substances can be found in common household products, furniture, mattresses, and more, including pesticides in and around the house. Recognizing the risks associated with VOCs and the potentially hazardous off-gassing process is crucial for protecting public health.  VOCs are a group of chemicals that can easily vaporize into the air at room temperature. These compounds are found in many everyday items, including furniture, cleaning products, pesticides, cosmetics, and even air fresheners. Some household products, particularly pesticides, can introduce their own set of risks in addition to the risks they pose due to their VOC content. VOCs can range from harmless to harmful, and their presence can have a […]

(Beyond Pesticides, October 30, 2023) TAKE ACTION. It is said that the definition of insanity is doing the same thing over and over again and expecting a different result. And so it goes with the U.S. Environmental Protection Agency’s (EPA) proposal to register a new genetically engineered pesticide for the Colorado Potato Beetle (CPB); this time with a pesticide that has not been fully evaluated for its adverse effects to people and the environment. [Submit a public comment before comment period ends today, October 30, 2023.] Chemical-intensive agriculture has failed to control CPB since resistance to DDT was identified in 1952 and has continued with every family of pesticides since then. CPB has been dubbed the billion-dollar-bug because of the investment in failed attempts of chemical manufacturers to control the insect, the profits generated by chemical companies despite this failure, and the resulting losses for chemical-intensive farmers—not to mention government expenditures for the registration of chemicals that have short efficacy, pollution costs associated with chemical production and use, and lost ecosystem services. But, EPA is at it again, registering a new novel pesticide active ingredient, Ledprona, which raises the stakes on potential harm. The only winners in this ongoing failure […]