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Metabolic Diseases, Including Diabetes and Obesity, Driven by Pesticide Exposure

Wednesday, September 27th, 2023

(Beyond Pesticides, September 27, 2023) A study published in Pesticide Biochemistry and Physiology finds organophosphate (OP), organochlorine (OC), and pyrethroid (PYR) pesticides have links to insulin resistance (IR) associated with metabolic disorders like diabetes, obesity, chronic kidney disease (CKD), and hypertension. Metabolic disorders are among the leading causes of morbidity and mortality, with over 11 percent (>37 million) of individuals in the U.S. having diabetes, and cases are growing by millions annually. Additionally, there is a rise in metabolic disorders among young people. Studies even find low levels of pesticide exposure during pregnancy or childhood cause adverse health effects, including metabolic disorders tied to gut microbiome disruption (dysbiosis). With increasing rates of diabetes and obesity, the two most prominent metabolic diseases in the study, cases among the global population, studies like these highlight the importance of evaluating how chemical contaminants deregulate normal bodily function through metabolic changes.  To investigate the association between pesticide exposure and insulin-related metabolic disorders in humans, researchers searched the PubMed database for articles, performing a systematic review. The study notes, “IR is defined as a pathological state in which a higher-than-normal level of insulin is required to produce the optimal response in cells.” The search generated 4,051 articles related to the topic. However, after excluding duplicates and […]

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Popular Pyrethroid Insecticides, Already Linked to Rheumatoid Arthritis, Associated with Osteoarthritis

Wednesday, September 20th, 2023

(Beyond Pesticides, September 20, 2023) Higher concentrations of a pyrethroid metabolite (3-PBA) in the body have an association with increased osteoarthritis (OA) risk among US adults, according to a study published in BMC Public Health. Regardless of analysis sensitivity and population subgroup (e.g., sex, socioeconomic status, etc.), the association between pyrethroid exposure and OA remains. Osteoarthritis is a degenerative joint disease resulting from the degradation (breakdown) of joint cartilage and underlying bone. This disease affects 1 in 7 U.S. adults and is the fourth leading cause of disability in the U.S. Unfortunately, OA is one of the most recently attributed pesticide-induced diseases associated with this dangerous class of chemical insecticides—harm to individual Americans that the U.S. Environmental Protection Agency (EPA) is not considering when it registers pesticides. To remedy the significant deficiencies in EPA’s reviews and protect residents from chronic disease, more and more communities are transitioning to safer, organic pest management practices that do not require pyrethroids and other toxic synthetic pesticides. Thus, this study and others like it highlight the need for increased monitorization of pyrethroid exposure among the general population. Using data from the 1999–2002 and 2007–2014 National Health and Nutrition Examination Survey (NHANES), this study explores the relationship between pyrethroid exposure and osteoarthritis. NHANES is […]

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Pollinator Health: The Climate Crisis Weakens Bees’ Ability to Withstand Pesticide Exposure

Wednesday, September 13th, 2023

(Beyond Pesticides, September 13, 2023) A study published in Global Change Biology finds climate change increases bees’ sensitivity to pesticide exposure, impairing the pollinators’ ability to respond to light (Ultra-Violet [UV] stimuli), reducing floral syrup consumption, and lessening longevity (length of life) up to 70 percent. Notably, the reduction in floral syrup consumption indicates nutritional stress that further impacts bee species’ fecundity (productiveness), driving bee declines. Unless more is done to combat the climate crisis, the current global warming scenario increasing bees’ sensitivity to pesticide exposure will continue to threaten all pollinator health. The pervasiveness of pesticide exposure, combined with climate change, threatens global species biodiversity. As has been widely reported, pollinators (such as bees, monarch butterflies, and bats) are a bellwether for environmental stress as individuals and as colonies. Pesticides intensify pollinators’ vulnerability to health risks (such as pathogens and parasites), with pesticide-contaminated conditions limiting colony productivity, growth, and survival. The globe is currently going through the Holocene Extinction, Earth’s 6th mass extinction, with one million species of plants and animals at risk, including pollinators. Pollinator declines directly affect the environment, society, and the economy. Without pollinators, many agricultural and nonagricultural plant species will decline or cease to exist as U.S. pollinator declines, particularly […]

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Illness Tied to Petrochemicals’ Impact on Body’s Essential Mast Cells (immune system regulators), Study Finds

Tuesday, August 22nd, 2023

A recently completed study (available in preprint before peer review) identifies the development of what the authors term Toxicant-Induced Loss of Tolerance (TILT), the constellation of symptoms associated with chemical exposures.

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Pesticide Exposure with Disproportionate Effects Increases Risk of Asthma

Wednesday, August 16th, 2023

(Beyond Pesticides, August 16, 2023) A study published in Environmental Science and Pollution Research further supports the indication that exposure to organophosphate insecticides (OPs) increases the risk of asthma among the U.S. general population. According to the Asthma and Allergy Foundation of America, “The burden of asthma in the United States falls disproportionately on people with low-income, senior adults, and Black, Hispanic and American Indian/Alaska Native people,” making these groups more susceptible to developing this chronic lung disease upon OP exposure.   Organophosphorus pesticides have a wide range of biological uses—from insecticides to flame retardants—that make these chemicals ubiquitous, significantly contributing to ecosystem contamination. Furthermore, while organophosphates have less bioaccumulation potential, residues are consistently present in human and animal blood, urine, tissues, and milk. Although research demonstrates that OPs are highly toxic, there remains an inadequate understanding of how OP exposure impacts body systems like the repository system. The respiratory system is essential to human survival, regulating gas exchange (oxygen-carbon dioxide) in the body to balance acid and base tissue cells for normal function. However, damage to the respiratory system can cause several issues—from asthma and bronchitis to oxidative stress that triggers the development of extra-respiratory manifestations like rheumatoid arthritis and cardiovascular disease. Therefore, the rise in respiratory illnesses and organophosphate […]

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Legislation Upholds Local Authority to Restrict Pesticide Use, Advances Other Reforms

Monday, August 14th, 2023

(Beyond Pesticides, August 14 2023) The Protect America’s Children from Toxic Pesticides Act of 2023 (PACTPA), introduced on July 28, 2023 in the U.S. House of Representatives (H.R. 5085) and previously introduced on February 2, 2023 in the U.S. Senate (S.269), seeks to improve federal pesticide law. Many advocates, while endorsing the Congressional effort, maintain that the law (Federal Insecticide, Fungicide, and Rodenticide Act—FIFRA) is structurally flawed in not requiring restrictions and the elimination of pesticides for which there are safer alternative practices and products. A key provision in the legislation includes language that affirms local authority to restrict pesticides. Both the House and Senate bills retain the basic structure of FIFRA, while strengthening various aspects of the current risk assessment-based approach to pesticide restrictions. Risk assessment in the current policy context assumes that pesticides are necessary and sets allowable levels of harm based on inadequate information on chemical effects—and margins of safety that allow for numerous uncertainties and disproportionate effects to vulnerable population groups. Importantly, the legislation does include a provision that grants communities local authority to restrict pesticides on all property, public and private, within their jurisdiction, allowing towns, cities, and counties to move society away from pesticide dependency and […]

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Chronic Kidney Disease of Unknown Origins Linked to Indoor Pesticide Use, Disproportionally Affecting Women

Tuesday, August 8th, 2023

(Beyond Pesticides, August 8, 2023) A study published in PLOS ONE finds a pointed, positive association between chronic kidney disease (CKD) of unknown origins (CKDu) and the use of indoor pesticides. Longer exposure times have an especially detrimental impact on kidney function, even among individuals without underlying diseases like diabetes mellitus and hypertension. The innovation of this study’s purpose highlights the lack of exposure-related studies on kidney health outcomes associated with indoor pesticide use. Although CKD risk increases with age and is associated with other health factors like smoking, heart disease, and diabetes, cases without clear causes are increasingly common, indicating that environmental factors are likely playing a role. Over six million people in the U.S. have kidney disease (i.e., nephritis [kidney inflammation], nephrotic syndrome [improper protein filtration], and nephrosis). Although many studies find an association between exposure to outdoor environmental contaminants like pesticides and CKD, the association between CKDu and indoor pesticides—whose uses are more commonly concentrated in homes— remains unclear. Therefore, studies like this highlight the need for comprehensive information regarding co-occurring exposure patterns and disease prevalence that can have global implications.  The study notes, “Previous research has highlighted the potential harm of pesticides on kidney function, particularly in outdoor uses. Our findings raise […]

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Regulators Ignore Mosquito Resistance to Pesticides, Promoting Disease Transmission

Monday, August 7th, 2023

(Beyond Pesticides, August 7, 2023) Why is the U.S. Environmental Protection Agency (EPA) allowing the use of pesticides under the “unreasonable adverse effects” to health or the environment standard of the federal pesticide law (Federal Insecticide, Fungicide, and Rodenticide Act [FIFRA]) if the pesticides quickly lose their efficacy? Pest resistance to pesticides is a well-known biological mechanism that becomes problematic when farmers are faced with crop failure and economic loss. It becomes especially threatening when the goal is to manage insects that are a disease vector and when the regulatory process ignores nonchemical management strategies that are efficacious and sustainable. Tell EPA, Governors, and Congress that given the certainty of pesticide resistance, ecologically-based mosquito management must replace a reliance on pesticides. Insect resistance to insecticides has been an issue since the introduction of DDT in the 1940s. Although most countries currently ban DDT use, several currently used insecticides pose the same threat. In fact, resistance is predicted by elementary population genetics, and the speed of its evolution is directly related to the toxicity—that is, strength of selection pressure—and inversely related to the generation length of the organism. When that target organism of the pesticide is a disease vector, like West […]

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The Growing Insecticide Resistance Issue Increases Concerns Over Deadly Disease Transmission Through Mosquitos

Wednesday, August 2nd, 2023

(Beyond Pesticides, August 2, 2023) A study published in Pest Management Science finds resistance to insecticides like pyrethroids are challenging attempts to control the mosquito Aedes aegypti (Ae. aegypti), the primary transmitter (vector) of dengue fever. While this study takes place in Bangladesh, resistance to biocides—whether to antibiotics, antimicrobials, or pesticides—is growing globally. Prevention of disease outbreaks is threatened by reliance on chemical biocides to which pathogens and their vectors develop resistance. In fact, resistance is predicted by elementary population genetics, and the speed of its evolution is directly related to the toxicity—that is, the strength of selection pressure—and inversely related to the generation length of the organism. (See PAY articles here and here, a PBS article here.) Insecticide resistance has been an issue since the introduction of DDT (dichlorodiphenyltrichloroethane) in the 1940s. Although most countries currently ban DDT use, the compound is not the only chemical pesticide promoting pest resistance. Several current-use insecticides pose the same threat. Areawide, indiscriminate spraying of insecticides is causing resistance to develop among many pests. Mosquitoes have become increasingly resistant to synthetic pyrethroids, in addition to other classes of insecticides, such as carbamates and organophosphates. Thus, this study demonstrates the need for sustainable and practical strategies […]

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Another Study Adds to Science Indicating Mothers’ Exposure to Pesticides During Pregnancy Increases Adverse Birth Outcomes

Wednesday, July 26th, 2023

(Beyond Pesticides, July 26, 2023) An exploratory study published in Environment International adds to the many studies demonstrating residential prenatal pesticide exposure can result in adverse birth outcomes. Residential exposure to five active pesticide ingredients (Ais) fluroxypyr-meptyl, glufosinate-ammonium, linuron, vinclozolin, and picoxystrobin has adverse effects on gestational age (GA), birth weight (BW), mortality after birth, child’s sex, premature development, low birth weight (LBW), small for gestational age (SGA), and large for gestational age (LGA). Pesticides’ presence in the body has implications for human health, especially during vulnerable life stages like childhood, puberty, pregnancy, and old age. Pesticide exposure during pregnancy is of specific concern as health effects for all life stages can be long-lasting. Birth and reproductive complications are increasingly common among individuals exposed to environmental toxicants like pesticides. The Centers for Disease Control and Prevention (CDC) reports birth defects are the leading cause of infant mortality, with one in every 33 infants born with an abnormality that results in death. Therefore, studies like this can help government and health officials safeguard human health by assessing adverse effects following prevalent chemical exposure.  Using a Dutch birth registry from 2009 to 2013, the researchers selected pregnant mothers over 16 years who were living in non-urban areas (who […]

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High Frequency of Household Pesticide Exposure Can Double the Risk of Parkinson’s Disease Among the General Population

Tuesday, July 11th, 2023

(Beyond Pesticides, July 11, 2023) A study published in Parkinsonism & Related Disorders finds high exposure to household pesticides increases the risk of developing Parkinson’s disease (PD) two-fold. There is a multitude of epidemiologic research on Parkinson’s disease demonstrating several risk factors, including specific genetic mutations and external/environmental triggers (i.e., pesticide use, pollutant exposure, etc.). However, several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Past studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the widespread commercialized use of household pesticides among the general population, few epidemiologic studies examine the influence household pesticides have on the risk of PD, although many studies demonstrate the association between PD onset via occupational (work-related) pesticide exposure patterns. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. Alzheimer’s ranks first. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and […]

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Prenatal Exposure to Organophosphate Pesticides Have Links to Behavior

Thursday, July 6th, 2023

(Beyond Pesticides, July 6, 2023) A study published in Environmental Health Perspectives finds concentrations of organophosphate (OP) metabolites in urine during the prenatal phase have links to adolescent/young adult externalizing (e.g., hyperactivity, aggression, attention problems) and internalizing (e.g., depression) behavior problems. Thus, prenatal exposure to OP pesticides can permanently affect behavioral health as children mature into adulthood. This study adds to the growing body of research reinforcing the adverse effects of organophosphate (OP) exposure on cognitive health and neurological development, especially for infants and children. Prenatal development is one of the most vulnerable periods of exposure, as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. Given research links to pesticide exposure and neurological and cognitive development, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns.  Researchers gathered two urine samples from mothers during pregnancy (at weeks 13 and 26) and five urine samples from offspring from the ages of six months to five years old to measure urinary dialkylphosphates (DAPs) (nonspecific OP metabolites). Subsequently, the study also assesses reports of […]

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Zebrafish Study Links Glyphosate Exposure to Heart Damage Through Aging and Reduced Creation of Cardiac Muscle Cells

Friday, June 30th, 2023

(Beyond Pesticides, June 30, 2023) Exposure to environmentally relevant concentrations of the herbicide glyphosate (GLY) has the potential to induce heart damage (cardiotoxicity) through the aging (senescence) of cells and a reduction of the number of rapidly increasing (proliferating) cells, according to a study published in Ecotoxicology and Environmental Safety. Specifically, glyphosate induces toxic effects on cardiomyocytes (cardiac muscles) responsible for contractions that pump the blood. Cardiovascular (heart) disease (CVD) is one of the leading causes of death in the U.S., with approximately 700,000 people dying annually of heart disease, equating to 25% of all U.S. deaths. Additionally, heart conditions are one leading cause of disability in the U.S. Research has shown that environmental pollutant exposure can increase the risk of developing cardiovascular disease, including stroke, heart attack, heart failure, atrial fibrillation, and cardiac arrest. Considering chemical exposure exacerbates adverse disease effects, reviews like these highlight the significance of evaluating synergism between diseases and toxic chemicals to safeguard human health. The study warns, “Our findings offer important information regarding the potential mechanisms of GLY cardiotoxicity toxicity. Notably, our study provides new insights into the relationship between GLY and senescence. Cardiac dysfunction of GLY to non-target organisms need to be noted in future study. Our study raises concerns about the […]

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Ecosystem Critical to All Pollinators: Popular and Unpopular Pollinator Guide

Friday, June 23rd, 2023

(Beyond Pesticides, June 23, 2023) Pollinators are especially important to the ecosystem. They pollinate plants by going from flower to flower and transferring pollen. Without pollinators, availability would be severely limited or cut off to many delicious foods, such as apples, almonds, cherries, blueberries, pumpkins, and many others. Many types of pollinators, like honey bees, bumble bees, and butterflies, are declining due to loss of habitat, widespread use of toxic pesticides, parasites, and disease. Help these important beneficial creatures by Not using toxic pesticides Planting pollinator habitats, like colorful flowers, gardens, and trees Telling your friends and family all about the importance of pollinators. Wild and Managed Bees Wild and managed bees play a crucial role in the global food system. About two-thirds of the world’s most important crops benefit from bee pollination, including coffee, cacao, and many fruits and vegetables. Wild pollination is becoming increasingly important with the growing instability of managed honey bee colonies. According to one study, wild bees’ agricultural value is now similar to that of honey bees, which are no longer considered wild in many regions due to their intense management. While many may prefer butterflies and birds to pay a visit to their gardens […]

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Pesticide Threat to Pollinators Decreases Agricultural and Economic Productivity, and Food Security

Thursday, June 22nd, 2023

(Beyond Pesticides, June 22, 2023) Since the early twentieth century, ‘migratory’ beekeepers have provided a critical service to U.S. agriculture by moving their hives seasonally to pollinate a variety of crops. Annually, commercial beekeeping adds between $15 and $20 billion in economic value to agriculture, which is a major industry in the United States, with 21.1 million full- and part-time jobs related to the agricultural and food sectors—10.5 percent of total U.S. employment. Before insects and pollinators like bees evolved to pollinate, pollination occurred through the wind, scattering the pollen from the plants and landing on other flowers that could reproduce. However, commercial pollination services contribute to increased yields. Without commercial pollination, food prices would rise, the farm sector would suffer globally, and the security and variety of the food supply would diminish. With the wild insect pollinator populations already in serious decline, commercial, migratory beekeeping is more than ever a vital piece of the agricultural economy. With pollinator decline, as an integral part of worldwide biodiversity collapse and the “insect apocalypse,” commercial beekeepers face collapse as well. The United Nations states that 80 percent of the 115 top global food crops depend on insect pollination, with one-third of all U.S. crops depending on pollinators, according to the U.S. […]

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National Pollinator Week 2023—Preserve and “BEE-Protective” of Pollinators!

Tuesday, June 20th, 2023

(Beyond Pesticides, June 20, 2023) Welcome to National Pollinator Week, during which time we recognize—and take action to protect—this important ecosystem link. Pollinators—bees, butterflies, birds, bats, and other organisms—make a critical contribution to plant health, crop productivity, and the preservation of natural resources, but their existence is threatened by their pesticide-contaminated habitat.   Check out this week’s calendar of activities and actions below! On social media, we will be featuring Pollinator Artwork submitted by the community, as well as the numerous cute (and “not so cute!”) pollinators that live in the world around us!  Also, check out our live Pollinator Poll! Follow us and like our page on Facebook, Twitter, Instagram and LinkedIn!  Monday: Juneteenth and Environmental Justice  As Pollinator Week launches with the celebration of Juneteenth, it is time to renew our commitment to environmental justice while seeking the adoption of transformational policies and practices that recognize the urgency to address disproportionate harm inflicted by toxic pesticide use.   Those fighting for environmental justice understand that the harms inflicted by toxic chemical production and use cause disproportionate adverse effects on people of color—from fenceline communities near chemical production plants to the hazardous and inhumane working conditions in agricultural fields, to […]

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This Juneteenth, We Highlight the Ongoing Fight for Environmental Justice

Friday, June 16th, 2023

(Beyond Pesticides, June 16, 2023) Juneteenth is a celebration of freedom for the last 250,000 enslaved people in Galveston, Texas, but it is also a reminder that justice has not historically been “swift” or complete for Black Americans. The holiday commemorates the abolition of slavery in Texas on June 19, 1865, two and a half years after the Emancipation Proclamation.  According to a 2022 Gallup Poll, 40 percent of Americans know “a little bit” or “nothing at all” about Juneteenth. While this is a significant improvement in comparison to the 60 percent for the aforementioned metric in the previous year (when the holiday was federally recognized), greater public awareness is needed. This holiday is a time for individuals and organizations to acknowledge and reflect on their past and current actions or inactions that perpetuate systemic racism. As known from the history books, the Emancipation Proclamation was signed on January 1, 1863, and the civil war ended on April 9, 1865. Juneteenth is a lesser-known anniversary commemorating the emancipation of enslaved people who received news of their freedom two and a half years after Abraham Lincoln’s freedom proclamation. While the technologies in the 19th century had a much slower travel time, […]

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Study Links Recurring Pregnancy Loss (RPL) with Pesticide Exposure

Wednesday, June 14th, 2023

(Beyond Pesticides, June 14, 2023) A study published in Scientific Reports finds a link between pesticide exposure and recurrent pregnancy loss (RPL) through oxidative stress and apoptosis (cell death) in the placenta. Recurrent pregnancy loss (RPL) is the loss of three or more successive pregnancies before 24 weeks of gestation (pregnancy) and signifies an underlying reproductive health issue. The study highlights that pesticides’ endocrine-disrupting (ED) properties can have varying adverse impacts on biological processes, including immunology, metabolism, and reproduction. Pregnant women experience frequent exposure to environmental pollutants that pose serious health risks to both mother and newborn. Many known pollutants (e.g., heavy metals, polychlorinated biphenyl, and pesticides) are chemicals with ED properties that can move from the mother to the developing fetus at higher exposure rates. Additionally, pregnant women are experiencing exposure to an increasing number of dangerous industrial chemicals. With a range of scientific data highlighting chemical exposures during pregnancy as a critical window of vulnerability, public awareness of these threats is growing. The study notes, “They are associated with an increasing placental OS [oxidative stress] and placental apoptosis. Specific measures should be taken to decrease maternal exposure to these pollutants’ sources, especially in underdeveloped and developing countries.” For RPL, the research investigated pesticide components in blood plasma, […]

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Pesticides and Neurotoxicity: The Link Between Mood Disorders and Pesticides Exposures

Wednesday, June 7th, 2023

(Beyond Pesticides, June 7, 2023) A systematic review of scientific literature published in Environmental Research on the development of mood disorders among pesticide applicators (farmers, landscapers, etc.) finds an increased risk of depression symptoms over the last decade. The evidence in the review highlights the presence of pesticide-specific biomarkers and biomarkers of depression that determine the positive association between pesticide exposure and the development of depressive symptoms. With more high-quality longitudinal studies to control sociocultural variables, researchers can directly pinpoint risks of developing depression, especially among agricultural workers and landscapers who use pesticides. Research on pesticide-induced diseases commonly investigates pesticide exposure concerning the development of various physical illnesses. However, previous studies show that occupational (work-related) risks of developing depression are high in agriculture, where pesticide use is rampant. Acute exposure to chemicals, including organophosphate, organochlorine, triazine, and carbamate pesticides, tends to put farmers at greater risk of suicide than the general population. There is a lack of information connecting pesticide exposure to the subsequent psychological (psychiatric) effects on the general population. Additionally, household pesticide exposure varies from occupational exposure via exposure frequency, duration, intensity, and type.   According to the World Health Organization (WHO), depression affects 322 million people globally, with the number of diagnosed patients increasing by 18.4% from 2005 to […]

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Scientists Identify 97 Pesticides and Chemical Pollutants in Study of Primate Population

Friday, June 2nd, 2023

(Beyond Pesticides, June 2, 2023) Scientists have identified 97 different types of pesticides and flame retardants in primate fecal samples, recently reporting their results in the journal Biology Letters. In Uganda’s Kibale National Park, researchers studied the chemical exposure of four species of primates (chimpanzees, Ugandan red colobus, olive baboons and red-tailed monkeys), adding to previous research on the subject. The chemicals demonstrate a measurable effect on primate growth and development, sparking considerable unease as to the future health of these critical species. This study shows how even within a protected national park, wildlife species are at risk from chemical pollution. According to advocates, the use of dangerous pesticides and flame retardants, therefore, must be entirely stopped in order to protect the future viability of wildlife species.  Scientists collected a total of 71 fecal samples from the four chosen species to measure levels of chemicals and hormones in a noninvasive manner. After sample analysis, researchers highlight three main groups of chemical pollutants: organochlorine pesticides (OCPs), brominated flame retardants (BFRs), and organophosphate esters (OPEs). Although in a protected area, wildlife species encounter humans through tourism, research, and human development surrounding the park. As these pesticides are so prevalent in areas of […]

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Residential Areas and Early Postnatal Complications for Pregnant Women Tied to Banned and Current Pesticides

Wednesday, May 31st, 2023

(Beyond Pesticides, May 31, 2023) A study published in Chemosphere supports accumulating scientific research confirming that prohibited and current use pesticides are readily detectable in the human placenta. All pregnant women experience exposure to a mixture of complex pesticides like DDT (prohibited organochlorine pesticide [OCP]) and chlorpyrifos (current use organophosphate [OP]), with concentrations high enough to increase possible adverse health risks to the fetus through a placental transfer of chemicals. Prenatal development in the intrauterine environment is one of the most vulnerable periods of exposure, as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. Given the over 1,300 research studies that demonstrate the link between pesticide exposure and general health effects, studies like this can help government and health officials identify how pesticides’ impact on the body elevates health concerns, especially for future and developing generations. The authors note, “This study highlights the urgent requirement for implementing alternative pest-control methods in agriculture, involving a reduction of chemical pesticides application. Due to the vital role of the placenta in fetal development and its non-invasive sampling, this kind of […]

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Beehive Products Contain Concentration of Pesticide Residues High Enough To Be a Risk to Consumer Health

Thursday, May 18th, 2023

(Beyond Pesticides, May 18, 2023) A study published in Food and Chemical Toxicology finds pesticide residues in beehive products pose a safety risk from dietary consumption. Beehive products (i.e., bee bread, propolis, beeswax, and royal jelly) from beekeeping or apiculture are said to have nutraceutical (health and medicinal benefits) properties. However, a wide range of pesticide residues (i.e., tau-fluvalinate, coumaphos, chlorfenvinphos, chlorpyrifos, and amitraz), especially acaricides for killing ticks and mites in hives, may accumulate in beehive products up to concentrations that pose a potential health risk. Environmental contaminants like pesticides are ubiquitous in the environment, with 90 percent of Americans having at least one pesticide compound in their body. Many of these chemical compounds remain in soils, water (solid and liquid), and the surrounding air at levels exceeding U.S. Environmental Protection Agency (EPA) standards. Therefore, individuals still encounter pesticide compounds at varying concentrations, adding to the toxic body burden of those harmful chemicals currently in use. The research methodology includes a review of the scientific literature on pesticide contamination in hive products and a dietary risk assessment. The risk assessment calculation uses scientific studies to determine the recommended daily intake values and concentration data. Researchers compare exposure values in products to health-based guidance, determining the potential acute and […]

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Pesticide Exposure Increases the Risk of All Seizure Disorders, Especially Epilepsy

Thursday, May 11th, 2023

(Beyond Pesticides, May 11, 2023) A study published in NeuroToxicology finds occupational (work-related), chronic exposure to pesticides increases risk factors of epilepsy, a neurological disorder causing unprovoked, reoccurring seizures. Mounting evidence over the past years shows that chronic exposure to sublethal (low) levels of pesticides can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, this study suggests environmental pesticide exposure increases seizure risk through mechanisms at molecular or subcellular levels. Approximately 3.4 million individuals in the U.S. live with epilepsy, and mortality from this disorder is rising nationwide. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood and urine samples and can increase neurotoxicity risk when crossing the brain barrier. Considering half of all epilepsy etiologies (causes) are of idiopathic (unknown) origins, studies like this highlight the importance of understanding how consistent chemical exposure can impact long-term health and disease prognosis. The study notes, “[The] approach to a real-world exposure scenario to pesticides in a large agriculture area over 17 years; […] can be linked to the novel approaches proposed for simulating real-life exposures, thus contributing to a better understanding of the real-life risk associated with long-term […]

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