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Study Provides First Combined Assessment of Multiple Classes of Pesticides in Human Blood

Friday, March 8th, 2024

(Beyond Pesticides, March 8, 2024) A major problem has vexed pesticide regulators and researchers for decades: Humans and other organisms almost always have multiple pesticides in their bodies, but techniques for assessing their combined effects, or cumulative body burden from multiple chemical classes are not typically available. A new study from Chinese and British researchers provides the first combined assessment of multiple classes of pesticides in human blood. The authors believe they are the first to develop a way to quantify multiple types of pesticides in human serum (clear liquid part of blood) as opposed to urine or from other sample collection methods. This is a tool that authors say is a more accurate way of assessing the real world exposure and ultimately the adverse impact of pesticide use on human health. The researchers had a small sample of 31 men and 34 pregnant women in Wuxi, China. They chose 73 pesticides and a few of their breakdown products to identify from three categories: fungicides, neonicotinoid insecticides, and triazine herbicides. Their testing protocol confirms their expectation that food—primarily produce—is the major source of pesticide exposures. This result reinforces Beyond Pesticides’ mission of supporting the shift in agriculture to pesticide-free methods […]

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Take Action: Federal Food Program Asked to Stop Feeding Children Pesticides that Contribute to Obesity

Monday, March 4th, 2024

(Beyond Pesticides, March 4, 2024) With 14.7 million children and adolescents in the U.S. recognized as obese by the Centers for Disease Control and Prevention (CDC) and the established connection with endocrine disrupting contaminants, including many pesticides, Beyond Pesticides is calling on federal food assistance programs to go organic. The problem of childhood obesity is higher in people of color and, as a result, is an environmental justice issue. According to CDC, the prevalence of childhood obesity is “26.2% among Hispanic children, 24.8% among non-Hispanic Black children, 16.6% among non-Hispanic White children, and 9.0% among non-Hispanic Asian children.” While childhood obesity is recognized as a serious problem, the National School Lunch Program of the U.S. Department of Agriculture (USDA)—although improved by the Healthy, Hunger-Free Kids Act of 2010—still provides lunches laced with obesogenic pesticides. To take meaningful steps against childhood obesity, school lunches must be organic. The program served 4.9 billion meals in fiscal year 2022 in over 100,000 public and nonprofit schools, grades Pre-Kindergarten-12. Contrary to popular opinion, the blame for the obesity epidemic cannot be attributed solely to diet and exercise broadly, but relates directly to pesticide and toxic chemical exposures, including residues in food, that may lead […]

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Literature Review on Obesogens Highlights the Long-Term Metabolic Impacts of Pesticide Exposure

Friday, March 1st, 2024

(Beyond Pesticides, March 1, 2024) A comprehensive research review published in Environment & Health analyzes existing research demonstrating the link between an increase in obesity and the proliferation of synthetic chemicals that “interfere with lipid metabolism.” The study documents over 50 obesogens with high-level human exposure rates, including per- and poly-fluoroalkyl substances (PFASs), phthalates (PAEs), and polybrominated diphenyl ethers (PBDEs), that can lead to lipid metabolism disruption including health impacts on the liver and insulin resistance, among other metabolic conditions such as diabetes, hypertension, cardiovascular disease, and dyslipidemia. Authors in this study highlight the scientific research community’s focus on adipose tissue and the liver, and a need to further explore effects on cardiovascular and kidney health. This anthology of research demonstrates the complexity of the threats associated with toxic pesticides, the severe limitations of their regulatory review, and the failure to consider organic practice and product alternatives that eliminate their use. Environmental obesogens are chemicals that are proven to have a health impact on metabolic systems relating to obesity. This review evaluates literature, going back to the 2006 obesogen hypothesis, on the metabolic impacts of environmental obesogens, including epidemiologic data, in vitro studies, and bioassays. Researchers scanned Web of Science, […]

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Take Action: Advocates Ask Congress to Include Protections from PFAS Contamination in Farm Bill

Tuesday, February 20th, 2024

(Beyond Pesticides, February 20, 2024) With health risks including developmental, metabolic, cardiovascular, and reproductive harm, cancer, damage to the liver, kidneys, and respiratory system, as well as the potential to increase the chance of disease infection and severity, per- and polyfluoroalkyl substances (PFAS) and their toxic trail of contamination in the environment is wreaking havoc with all life. The use of PFAS in industrial and commercial applications has led to widespread contamination of water and biosolids used for fertilizer, poisoning tens of millions of acres of land and posing a significant threat to the biosphere, public health, gardens, parks, and agricultural systems. Farmers and rural communities, in particular, bear the brunt of this contamination, as it affects their drinking water, soil quality, and livestock health.   Tell Congress that the Farm Bill must include the Relief for Farmers Hit with PFAS Act and the Healthy H2O Act to protect farmers and rural communities from PFAS contamination.  Led by Chellie Pingree (D-ME), U.S. Senators Tammy Baldwin (D-WI), and Susan Collins (R-ME), a bipartisan and bicameral bill—the Relief for Farmers Hit with PFAS Act—has been introduced to provide assistance and relief to those affected by PFAS. A second bill, the Healthy H2O Act, introduced by Representatives Pingree and David Rouzer (R-NC) and Senators Baldwin […]

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Study Finds Novel Relationship Between Shingles and Pesticide Exposure

Wednesday, November 29th, 2023

(Beyond Pesticides, November 29, 2023) A study published in Environment International finds high pesticide exposure incidence associated with shingles, a varicella-zoster virus (the same highly contagious virus that causes chickenpox) that reactivates in the body after having chicken pox. Shingles is a painful condition with a blistering rash that can lead to vision and hearing loss, brain and lung inflammation, and even death if not treated. Since shingles manifest decades after initial exposure, and the association is strongest among individuals already hospitalized for pesticide-related illnesses, researchers find the long-term/chronic effects most concerning. Although dermal pesticide exposure can cause a range of adverse reactions, including dermatitis, allergic sensitization, and cancer, any route of exposure can exacerbate dermal manifestations through immune system response, causing virus-based skin reactions like shingles. People encounter toxic chemicals daily. However, frequent use of pesticides, including the use of everyday products like cleaning supplies, personal care products, agricultural chemicals, fabrics, non-stick cookware, and general airborne pollution, exacerbate chemical exposure risks. Dermal exposure is the most common pesticide exposure route, composing 95 percent of all pesticide exposure incidents, and is a significant concern for occupational (work-related) health. The study notes, “[The] findings of elevated shingles risk associated with acute, clinically relevant pesticide exposures also highlights […]

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Commentary and Action: Court Decision and History Calls into Question Value of Pesticide Law

Monday, November 13th, 2023

(Beyond Pesticides, November 13, 2023) The news of a federal Appeals Court’s reversal of a U.S. Environmental Protection Agency (EPA) decision in early November calls into question the value of the basic structures, processes, and authorities of pesticide law that the public has been told are protective of health and the environment. After decades of review and litigation, this reversal, especially on a highly neurotoxic insecticide like chlorpyrifos, identifies a fundamentally flawed system that does not protect the health of people, in this case, children’s brains. >>Tell your governor and mayor to adopt policies that support organic land management.  It was EPA’s finding that chlorpyrifos was destructive of the nervous system, particularly in children, and the functioning of the brain that led to an EPA-negotiated chemical company (Corteva/Dow Chemical) settlement in 1999 (took effect in 2000) that removed residential uses of chlorpyrifos from the market. The 2020 EPA decision, 21 years later, to stop agricultural uses followed another Appeals Court decision, departing from the agency’s usually long drawn-out negotiations that ultimately compromise health and the environment. EPA banned agricultural uses of chlorpyrifos in 2016 in the Obama Administration, but the decision was reversed by the Trump Administration in 2017. Because […]

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A Very Slow EPA Settlement Process Keeps a Harmful Herbicide on the Market

Friday, September 15th, 2023

(Beyond Pesticides, September 15, 2023) The U.S. Environmental Protection Agency suspended the registration of the herbicide dimethyl tetrachloroterephthalate (DCPA) (also widely known as Dacthal), effective August 22, 2023 and leaves existing stocks (products containing DCPA manufactured before August 22) available on the market. The decision is one of a series of EPA attempts dating to 2013 to get more data from the manufacturer as the agency considers reregistration of DCPA. The suspension is toothless, however, since EPA did not totally close the book on this chemical. Six days before the suspension, EPA signed a settlement agreement with the sole manufacturer, AMVAC Corporation, to reinstate the registration upon receipt of the complete toxicological data—that is, animal and laboratory tests— needed to determine the chemical’s safety and how and where it can be used. DCPA is currently classified by EPA as a possible human carcinogen and has also been shown to be a thyroid hormone disrupter. DCPA is regulated under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). Pesticides are supposed to undergo reregistration every 15 years to take new science into consideration, but this process is glacial. Congress amended FIFRA in 1988 to speed up reregistration of products registered before 1984, and […]

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EPA’s Failure to Assess Multiple Chemical Exposure Threat Creates Environmental Injustice, Says Inspector General

Wednesday, September 6th, 2023

(Beyond Pesticides, September 6, 2023) In late August, the Office of the Inspector General (OIG) at the U.S. Environmental Protection Agency (EPA) released a report concluding that EPA “took a siloed approach” to the cumulative impacts of chemical exposures and the disproportionate nature of those exposures. This approach keeps different parts of the EPA from coordinating their efforts and hinders understanding of the breadth and depth of chemical exposures. OIG reached this disturbing finding despite the issuance of several executive orders by President Biden requiring EPA to develop policies and actions to assess cumulative impacts of chemical exposures across departments, laws, and environmental media (air, water, bodies, food etc.) and to pay more attention to environmental justice. Beyond Pesticides has stressed that the whole constellation of chemical exposures and effects should be considered when governments set public policies and regulations. Just last March, Daily News covered another OIG report castigating EPA for betraying its mission by failing to address the fact that very high levels of per- and polyfluoroalkyl compounds known as “forever chemicals” have been found in some common pesticides. OIG also berated EPA for succumbing to Donald Trump’s interference with setting toxicity values for the “forever chemical” perfluorobutane […]

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Biosolids/Sewage Sludge Widely Used without Complete Safety Assessment

Monday, July 24th, 2023

(Beyond Pesticides, July 24, 2023) Sewage sludge, also known as biosolids, is a byproduct of sewage treatment and is used as a source of organic matter for amending soil in nonorganic agriculture and landscaping. EPA has published a list of 726 chemicals found in biosolids in the National Sewage Sludge Surveys. This list does not include the per- and polyfluoroalkyl substances (PFAS), which are emerging contaminants of biosolids. Tell your Governor and local officials to ban the use of biosolids in farms and parks, until there is adequate testing of toxic residues—which does not currently exist. In addition to PFAS (also referred to as “forever chemicals”), persistent toxic pollutants found in biosolids include: inorganic chemicals such as metals and trace elements; organic chemicals such as polychlorinated biphenyls or PCBs, dioxins, pharmaceuticals, and surfactants; and pathogens including bacteria, viruses, and parasites. Regulation of biosolids by the U.S. Environmental Protection Agency (EPA) has been found by the EPA Office of Inspector General (OIG), in its report EPA Unable to Assess the Impact of Hundreds of Unregulated Pollutants in Land-Applied Biosolids on Human Health and the Environment, to be inadequate. Lacking sufficient oversight at the federal level, action to protect health and the environment falls […]

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Deadly Pesticide Poses an Increased Risk of Hormone-Associated Reproductive Cancers in Women

Thursday, July 13th, 2023

(Beyond Pesticides, July 13, 2023) A study published in Environmental Science and Pollution Research finds exposure to p-Dichlorobenzene (p-DCB), a chlorophenol compound with uses as an insecticide, disinfectant, repellent, fumigant, fungicide, and deodorizer, can increase the risk of common endocrine (hormone)-mediated reproductive cancers (i.e., breast, uterine, and ovarian) in women. P-DCB or paradichlorobenzene has carcinogenic (cancer-causing) properties and the chemical has been banned in the European Union (EU) since 2005 for air fresheners and 2008 for mothballs. Being a chlorinated aromatic hydrocarbon (with benzene) compound (chlorobenzene), in addition to its cancer-causing properties, p-DCB can cause acute illnesses like headaches, numbness, sleepiness, nausea and vomiting and chronic effects like nervous system disorders leading to depression, and impact on the brain, birth outcomes, reproductive system, liver, and kidneys. Pesticides have a long history associated with endocrine-disrupting properties that induce various molecular changes, prompting disease development. Adding to the science, a similar review published in Environmental Exposure, Biomonitoring, and Exposure Assessment highlights how specific estrogen-mimicking pesticides increase the risk of disease, particularly hormone-related cancers among women (e.g., breast, ovarian, and endometrial cancer) and men (i.e., testicular, prostate cancer).PDCB, also known as para-dichlorobenzene, contains the carcinogen benzene and is chlorine-based (a chlorinated aromatic hydrocarbon compound), which in December 2019 […]

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High Frequency of Household Pesticide Exposure Can Double the Risk of Parkinson’s Disease Among the General Population

Tuesday, July 11th, 2023

(Beyond Pesticides, July 11, 2023) A study published in Parkinsonism & Related Disorders finds high exposure to household pesticides increases the risk of developing Parkinson’s disease (PD) two-fold. There is a multitude of epidemiologic research on Parkinson’s disease demonstrating several risk factors, including specific genetic mutations and external/environmental triggers (i.e., pesticide use, pollutant exposure, etc.). However, several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Past studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the widespread commercialized use of household pesticides among the general population, few epidemiologic studies examine the influence household pesticides have on the risk of PD, although many studies demonstrate the association between PD onset via occupational (work-related) pesticide exposure patterns. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. Alzheimer’s ranks first. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and […]

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New Viewpoint on the Historic Link between Endocrine Disrupting Chemicals and Cancer Discussed

Thursday, May 25th, 2023

(Beyond Pesticides, May 25, 2023) A review of scientific literature published in the Journal of Endocrinological Investigation demonstrates exposure to past and current-use endocrine-disrupting chemicals (EDCs), like pesticides, have a long history of severe adverse human health effects. Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem) present in nearly all organisms and ecosystems. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Endocrine disruption can lead to several health problems, including hormone-related cancer development (e.g., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Therefore, studies related to pesticides and endocrine disruption help scientists understand the underlying mechanisms that indirectly or directly cause infertility, among other health issues. The review notes, “New evidence supports the role of other EDCs as possibly carcinogenic and pregnant women should avoid risk area and exposure. The relationship between EDCs and cancer supports the need for effective prevention policies increasing public awareness.” The review examines the relationship between EDCs and various hormone-mediated various (i.e., breast, prostate, testicle, ovary, and thyroid) to determine the carcinogenicity of the chemicals and their impact on public […]

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Allowance of “Forever” or “Legacy” Chemicals Causes Insurmountable Multi-Generational Poisoning

Monday, May 15th, 2023

(Beyond Pesticides, May 15, 2023) Say “legacy contaminant” or “forever chemical” and most people today think “PFAS” (perfluoroalkyl substances), but PFAS are just the latest persistent toxic chemicals recognized as presenting an alarmingly difficult cleanup problem. Fortunately, steps are being taken by governments and businesses to eliminate use of PFAS. (Organic farmers concerned about the integrity of their products have been leaders in these efforts.) Although government officials often devote considerable energy and resources to cleaning up contamination, the continued manufacturing of these chemicals and their release into the environment creates a futile situation. The U.S. is a signatory to the 2001 Stockholm Convention, which provides an international framework for moving persistent organic pollutants out of commerce, but the U.S. Senate never ratified it.     Ask your Senators to ratify the Stockholm convention. Tell EPA that persistent toxic pesticides must be considered to pose an “unreasonable risk to the environment under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA),” which must result in cancellation of their registrations.  PFAS contamination is just the latest chapter of a very old story. Legacy contamination of our bodies and the environment is partly a result of a slow piecemeal approach to eliminating these toxic chemicals. […]

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Persistent Pesticides and Other Chemicals Have Made “Legacy” a Dirty Word as “Forever” Chemicals

Friday, May 12th, 2023

(Beyond Pesticides, May 12, 2023) With the growth of chemical-intensive land management over the last century, the world has been held captive by pesticide companies. For part of that time, it could be said the modern society has suffered from Stockholm Syndrome, a theory about abusive relationships in which one party exerts power over the other using threats, fear, and lies and the victim comes to depend on the perpetrator emotionally. During the so-called “Green Revolution” (circa 1945-1985), the world came to depend on vast amounts of fertilizers and herbicides, insecticides, and fungicides. Many people believed that food, clothing, and shelter made from naturally-occurring materials such as fruit, flax and wood could not be provided to the world without pesticides. It seemed that science and commerce could indefinitely raise the standard of living around the world, perhaps leading to world peace. This is not what happened. Soon observers noticed the harmful effects of many pesticides, including their persistence in the environment, their tendency to accumulate in the bodies of humans and wildlife, and their influence on the risk of contracting many diseases, from cancer to asthma—not to mention the Darwinian inevitability of pest resistance. By the turn of the 20th […]

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Research Further Associates Widespread Atrazine Exposure to Breast Cancer

Thursday, March 30th, 2023

(Beyond Pesticides, March 30, 2023) A study published in Ecotoxicology and Environmental Safety finds that the commonly used herbicide, atrazine, promotes breast cancer development through suppression of immune cell stimulation, and thus function, and upregulation of enzymes mediating tumor development. According to the Centers for Disease Control and Prevention (CDC), breast cancer is a disease that causes breast cells to grow out of control, with the type of breast cancer depending on the cells themselves. Several studies and reports, including U.S. Environmental Protection Agency (EPA) data, identify hundreds of chemicals as influential factors associated with breast cancer risk. Breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. Past studies suggest genetic inheritance factors influence breast cancer occurrence. However, genetic factors only play a minor role in the incidence of breast cancer, while exposure to external environmental factors (i.e., chemical exposure) appears to play a more notable role. One in ten women will receive a breast cancer diagnosis, and genetics can only account for five to ten percent of cases. There are grave concerns over exposure to endocrine (hormone) disrupting chemicals and pollutants that cause adverse health effects. Therefore, advocates point to the need for national […]

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Neonicotinoid Insecticides Adversely Affect Nervous System Health, According to Study

Thursday, January 19th, 2023

(Beyond Pesticides, January 19, 2023) Research published in Environmental Health Perspectives finds the presence of nine various neonicotinoids (neonics) and six neonic metabolites within human cerebrospinal fluid (CSF). CSF is an essential part of the central nervous system (CNS), especially for CNS development. Specific chemical biomarkers (measurable indicators of biological state), like pesticides, found in CSF are useful for diagnosing and evaluating numerous neurological diseases. The nervous system is an integral part of the human body and includes the brain, spinal cord, a vast network of nerves and neurons, all of which are responsible for many of our bodily functions—from sensed to movement. However, mounting evidence over the past years shows that chronic exposure to sublethal (low) levels of pesticides can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. The impacts of pesticides on the nervous system, including the brain, are hazardous, especially for chronically exposed individuals (e.g., farmworkers) or during critical windows of vulnerability and development (e.g., childhood, pregnancy). Researchers identify the role agricultural chemicals play in CNS impacts causing neurological diseases, like amyotrophic lateral sclerosis (ALS) and Parkinson’s disease, dementia-like diseases such as Alzheimer’s, and other effects on cognitive function. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood […]

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Take Action: Bill Addresses PFAS; Remediation Needed for All Legacy Chemicals

Monday, November 7th, 2022

(Beyond Pesticides, November 7, 2022) The Maine Congressional delegation — Senators Collins (R) and Angus King (I), and Representatives Chellie Pingree (D) and Jared Golden (D), along with New Hampshire Senator Jeanne Shaheen (D) — have  introduced a bipartisan bill — the Relief for Farmers Hit with PFAS Act — to help farmers who have been adversely affected by the scourge of PFAS (perfluoroalkyl and polyfluoroalkyl substances) chemicals. The bills are the identical S. 5070 and H.R. 9186, both titled “Relief for Farmers Hit with PFAS Act.” Tell your U.S. Senators and Representative to cosponsor the Relief for Farmers Hit with PFAS Act. If they are already cosponsors, thank them. Tell EPA to stop the spread of legacy chemicals. PFAS chemicals, also known as “forever chemicals,” are legacy contaminants or those whose historical use, including many decades ago in some instances, has led to their toxic persistence in the environment and in organisms. PFAS chemicals are not the only legacy contaminants. Others include wood preservatives, DDT, dioxins, and the termiticide chlordane. Unfortunately, some of these continue to be added to the environment, sometimes inadvertently, but also intentionally, particularly through pesticide use. As indicated by the title of these bills, farmers […]

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Advocates Urge Elimination of Toxic Pesticide Use to Prevent Breast Cancer

Monday, October 24th, 2022

(Beyond Pesticides, October 24, 2022) We need prevention of the causes of breast cancer, not just awareness. In 1985, Imperial Chemical Industries and the American Cancer Society declared October “Breast Cancer Awareness Month” as part of a campaign to promote mammograms for the early detection of breast cancer. Unfortunately, most of us are all too aware of breast cancer. Detection and treatment of cancers do not solve the problem. Tell EPA to evaluate and ban endocrine-disrupting pesticides, and make organic food production and land management the standard that legally establishes toxic pesticide use as “unreasonable.”  Next to skin cancer, breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. Genetic factors only play a minor role in breast cancer incidence, while exposure to external environmental factors such as pesticides plays a more notable role. For breast cancer, one in eight women will receive a diagnosis, and genetics can only account for five to ten percent of cases. Therefore, it is essential to understand how environmental exposure to chemicals like pesticides can drive breast cancer development. Several studies and reports, including U.S. Environmental Protection Agency (EPA) data, identify hundreds of chemicals as influential factors associated with breast cancer […]

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Ingestion of Real-World Pesticide Residues in Grain Threatens Bird Offspring More than Parents

Thursday, September 8th, 2022

(Beyond Pesticides, September 8, 2022) A study published in Environmental Pollution finds parental exposure to real-world, sublethal concentrations of pesticide residues on grains is a major contributor to unfavorable offspring development among foraging birds. Parents’ ingestion of grains with conventional pesticide residues, whether from contaminated or pesticide-treated seeds, results in chronic exposure that adversely affects offspring health, even at low doses. The adverse effects pesticides and other environmental pollutants have on birds are amply documented and researched. Although many studies evaluate acute or chronic health implications associated with pesticide exposure in a single generation, there is a lack of information on multi-generational impacts that can provide vital information on the fundamental survivability or fitness of bird species. Considering this study emphasizes parental exposure to environmental pollutants can have adverse consequences for future generations, it is necessary that future risk assessments for birds address these implications when implementing agricultural pesticide policies. The study notes, “[S]ublethal effects of such compounds [pesticides] on non-target species should be included in the regulation. Moreover, as agroecosystem pollution is not resulting only from pesticides, there is an urgent need to analyze cocktail effects, not only between molecules of pesticides but also between pesticides and other pollutants such as […]

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Glyphosate Weed Killer Crosses Blood-Brain Barrier, Linked to Alzheimer’s and Other Neurodegenerative Diseases

Thursday, August 4th, 2022

(Beyond Pesticides, August 4, 2022) An Arizona State University (ASU) study shows that the popular herbicide glyphosate can infiltrate the brain through the blood (blood-brain barrier), increasing neurological disease risk. The blood-brain barrier filters various molecules entering the brain from the circulatory system. However, the permeation of glyphosate molecules elevates the expression of TNFα and the accumulation of soluble beta-amyloid (Aβ) proteins in the brain and has associations with immune, inflammatory, and neurodegenerative diseases like Alzheimer’s disease (AD). More than 6 million people in the U.S. are living with Alzheimer’s, and cases are expected to double by 2050. Although Alzheimer’s research has focused heavily on finding genetic causes of the disease, fewer than half of cases are genetic. Thus, researchers are now evaluating how environmental contaminants may increase disease risk. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood and urine samples and can increase neurotoxicity risk when crossing the brain barrier. Therefore, studies like this highlight the importance of understanding how chemical accumulation in the body can impact long-term health and disease prognosis. The study notes, “Brain glyphosate correlates with increased TNFα levels, suggesting that exposure to this herbicide may trigger neuroinflammation in the brain, which may […]

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Common Fungicide Again Linked to Parkinson’s Disease with Molecular Disruption

Thursday, June 30th, 2022

(Beyond Pesticides, June 30, 2022) A study by Zhongnan University and Shandong University in China finds that the broad-spectrum fungicide maneb increases Parkinson’s disease (PD) risk and development through alterations in protein and metabolite pathways, resulting in neurotoxicity. Several studies find exposure to chemical toxicants, like pesticides, have neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, this study suggests neurological damage from oxidative stress, cell dysfunction, and synapses impairment, among others, increases the incidence of PD subsequent to pesticide exposure. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While only 10 to 15 percent of PD cases are genetic, PD is quickly becoming the world’s fastest-growing brain disease. Therefore, research like this highlights the need to examine molecular mechanisms involved in altering chemical […]

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Farmed Salmon Just as Toxic to Human Health as Junk Food

Thursday, June 16th, 2022

(Beyond Pesticides, June 16, 2022) Farmed salmon serves as an inferior food source, accumulating more toxic chemicals in fatty tissue with fewer healthy nutrient properties based on a study from the University of Bergen, Norway and Alternative Medicine Review. However, the issue of toxic chemical contamination in fish dates back decades with investigations demonstrating high levels of persistent organic pollutants (POPs), including polybrominated diphenyl ethers (PBDEs) flame retardants restricted or banned in the U.S. and U.K., polychlorinated biphenyl (PCBs), dioxin (a by-product of pesticide manufacturing), and ethoxyquin (a pesticide preservative in fish feed). The aquaculture industry (e.g., farmed seafood/fish) repeatedly faces sustainability issues, failing to adhere to environmental regulations and threatening marine health. Extensive use of pesticides in local marine ecosystems has induced coastal habitat loss and increased genetic and health risks to wild marine populations. Moreover, insecticides used to kill salmon parasites (e.g., fish lice) has led to widespread disease persistence and pest resistance. Marine species biodiversity is rapidly declining due to overfishing, global warming, pathogens, and pollution. Thus, further biodiversity loss can change aquatic and terrestrial ecosystem functions and reduce ecosystem services. Food analysis results find the consumption of farmed salmon fillets contributes to higher rates of metabolic disorders, including diabetes and obesity. These farmed salmon also contain levels […]

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Plastic Coated Pesticides Adding to Soil and Ecosystem Contamination with Microplastics

Friday, June 3rd, 2022

(Beyond Pesticides, June 3, 2022) It is hardly news that plastics are a huge environmental problem, but three features of the plastic saturation of our planet are not well or widely recognized. One is the exacerbation of the climate emergency via emissions from the feedstocks for, and production and use of, plastics. Another is that proffered in a late 2021 report by the Food and Agriculture Organization of the United Nations: “the land we use to grow our food is contaminated with even larger quantities of plastic pollutants” than the well-publicized amount of plastics in our oceans. The third is the little-known issue of the plastic coating of some synthetic pesticides and fertilizers, as investigated by a recent report from the Center for International Environmental Law (CIEL). Beyond Pesticides has written about the “contributions” of plastics to the climate crisis, as well as issues related to uses of plastics in organic agriculture and the scourge of chemically intensive farming. An enormous amount of plastic in thousands of forms is produced globally each year. Toxic plastic pollution is now found, as The Guardian puts it, “from the summit of Mount Everest to the deepest oceans.” A frequently cited and chilling metric is this: the total mass of plastics […]

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