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Daily News Blog

Archive for the 'MCPA' Category


12
Jan

Pesticides Not Only Linked to Parkinson’s Disease Development, But Accelerating Disease Symptoms

(Beyond Pesticides, January 12, 2023) Exposure to certain pesticides among individuals diagnosed with Parkinson’s disease (PD) can increase the risk of symptom progression. According to a study published in Science of the Total Environment, nearly 20 percent of pesticides associated with the onset of PD also increase the risk of faster decline in motor and non-motor function. Several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Past studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the association between PD onset via pesticide exposure patterns, few epidemiologic studies examine the influence pesticides have on worsening motor and non-motor symptoms in PD. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While […]

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16
Oct

Agricultural Crop Density Linked to Childhood Cancer in Midwest

(Beyond Pesticides, October 16, 2015) According to a new study, living in crop-dense regions is linked to increased leukemia and central nervous system cancers in children. Although there is a litany of scientific literature that highlights the link between pesticide exposure and childhood illness, this study is one of few that examines the relationship between residential exposures to agricultural pesticides via crop density and adverse health outcomes, and may serve as a basis for further investigation into childhood cancer rates in areas where agricultural pesticides are highly used. The study, titled Agricultural crop density and the risk of childhood cancer in the Midwestern United States: an ecologic study,  was published in the journal Environmental Health. Using crop density as a surrogate for residential exposure to agricultural pesticides, the study linked county-level agricultural census data and cancer incidence data for children between the ages 0 to 4 in six Midwestern states and found evidence of an association between childhood cancer incidence and the production of crops such as dry beans, oats, and sugar beets. Researchers found statistically significant exposure-response relationships for dry beans and total leukemias and acute lymphoid leukemias, oats and acute myeloid leukemias, and sugar beets and total leukemias. […]

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10
Nov

GAO Report Sounds Alarm Again on Poor Pesticide Controls

(Beyond Pesticides, November 10, 2014) According to a new Government Accountability (GAO) report, the U.S. Food and Drug Administration (FDA) does not test food for several commonly used pesticides with established tolerance levels —including glyphosate, one of the most commonly used pesticides in the U.S. This and other disturbing findings documented in GAO’s report,  Food Safety: FDA and USDA Should Strengthen Pesticide Residue Monitoring Programs and Further Disclose Monitoring Limitations,  issued last Thursday, sounds an alarm that GAO began sounding  in the 1980’s in several reports that identify shocking limitations of  FDA’s approach to monitoring for pesticide residue violations in food. GAO sharply criticizes FDA for not using statistically valid methods consistent with Office of Management and Budget (OMB) standards to collect information on the incidence and level of pesticide residues. In fact, GAO states that it “was unable to find publicly available estimates of the overall toxicity or risk associated with the use of agricultural pesticides in the United States.” According to GAO, FDA is testing less than one-tenth of one  percent of all imported fruits and vegetables and less than 1 percent of domestic fruits and vegetables.  The report is also critical of U.S. Department of Agriculture’s (USDA) […]

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02
May

Review Links Glyphosate to non-Hodgkin’s Lymphoma

(Beyond Pesticides, May 2, 2014) A recent review, published in the International Journal of Environmental Research and Public Health, examines the interaction between widely used agricultural herbicides, like glyphosate, the active ingredient of Roundup products, and the risk of developing non-Hodgkin’s lymphoma (NHL). The study represents one of the most comprehensive reviews on the topic of occupational exposure to pesticides in scientific literature, demonstrating their clear harm to human health. The study, “Non Hodgkin lymphoma and occupational exposure to agricultural pesticide chemical groups and active ingredients: A systematic review and meta-analysis,” reviews almost thirty years of epidemiological research, examining occupational exposure of farmers to 80 active ingredients, and 21 chemicals groups to clarify their role in the development of NHL. Analyzing 44 papers, the study opens its discussion by mentioning the ”˜striking increase’ in incidents of NHL over the past 30 years. The study attempts to reconcile apparent trends of low mortality but high incidents of cancer among farm workers, pointing out that exposure to agricultural pesticides are often associated with signficint sub-lethal impacts. Researchers Maria Leon Roux, PhD., and Leah Schinasi, PhD. at the International Agency for Research on Cancer in the Environment and Radiation section, said that the […]

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15
Oct

Common Herbicides Block Important Nutrient Sensor in Humans

(Beyond Pesticides, October 15, 2009) New research from the Monell Center and the Mount Sinai School of Medicine reveals that phenoxy herbicides block T1R3, a nutrient-sensing taste receptor found in the pancreas and intestines of humans. These commonly used herbicides were not previously known to act on the T1R3 receptor, nor has any animal testing revealed any indication of this. The specific effects are unique to humans; thus, phenoxy herbicides may have adverse metabolic effects in humans that would have gone undetected in studies on rodents. The T1R3 receptor is a critical component of both the sweet taste receptor and the umami (amino acid) taste receptor. First identified on the tongue, emerging evidence indicates that T1R3 and related taste receptors also are located on hormone-producing cells in the intestine and pancreas. These internal taste receptors detect nutrients in the gut and trigger the release of hormones involved in the regulation of glucose homeostasis and energy metabolism. “Compounds that either activate or block T1R3 receptors could have significant metabolic effects, potentially influencing diseases such as obesity, type II diabetes and metabolic syndrome,” noted Monell geneticist and study leader Bedrich Mosinger, M.D., Ph.D. The study, co-authored by Emeline Maillet from the Department […]

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29
Sep

Children Living Near Agricultural Pesticide Use Have Higher Cancer Rate

(Beyond Pesticides, September 29, 2009) A new study reveals that children exposed to agricultural pesticides applied near their home have up to twice the risk of developing the most common form of childhood leukemia, according to the Northern California Cancer Center (NCCC). The study, “Residential proximity to agricultural pesticide applications and childhood acute lymphoblastic leukemia,” published in the October issue of Environmental Research, used a unique California database to reveal an elevated risk in acute lymphoblastic leukemia (ALL) among children living near applications of certain categories of pesticides used in agriculture. The study, led by Rudolph Rull, Ph.D., shows an elevated risk of ALL associated with moderate exposure, but not high exposure, to pesticides classified as organophosphates (odds ratio (OR) 1.6), chlorophenoxy herbicides (OR 2.0), and triazines (OR 1.9), and with agricultural pesticides used as insecticides (OR 1.5) or fumigants (OR 1.7). California is one of the few states in the country that requires active reporting of pesticide applications, including time, place, and the type and amount of pesticide used. For this study, researchers were able to link children’s entire residential histories from birth to the time of case diagnosis to this pesticide-use reporting database and identify agricultural pesticides that […]

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14
Oct

Study Shows Herbicides Increase Risk of Non-Hodgkin’s Lymphoma

(Beyond Pesticides, October 14, 2008) Exposure to glyphosate or MCPA can more than double one’s risk of developing non-Hodgkin lymphoma (NHL), according to a new epidemiological study published in the October issue of the International Journal of Cancer. The case-control study finds a 2.02 odds ratio (OR) for exposure (two times the chance of contracting the illness) to glyphosate, a 2.81 OR for exposure to MCPA, and a 1.72 OR for exposure to herbicides. According to EPA, glyphosate is the most commonly used pesticide in the U.S. with 103 to 113 million pounds used annually. MCPA is a phenoxyacetic acid pesticide, a family of pesticides that has previously been linked to cancer and includes 2,4-D and mecoprop (MCPP). NHL is a cancer of the immune system. There are several different types of NHL, which are differentiated by the type of immune cell that is cancerous, the characteristics of the cancerous cell, and different genetic mutations of the cancerous cells. Treatment for NHL varies depending on NHL type, patient age, and other existing medical conditions. The incidence of NHL has been increasing over the past several decades. The link between pesticides and cancer has long been a concern. While agriculture has […]

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